Id |
Subject |
Object |
Predicate |
Lexical cue |
T1 |
0-77 |
Sentence |
denotes |
Fatigue in ankylosing spondylitis: treatment should focus on pain management. |
T2 |
78-89 |
Sentence |
denotes |
OBJECTIVES: |
T3 |
90-166 |
Sentence |
denotes |
Fatigue is an important symptom associated with ankylosing spondylitis (AS). |
T4 |
167-310 |
Sentence |
denotes |
This study examines patients' perspectives and clinical associations of fatigue to help inform potential strategies to alleviate fatigue in AS. |
T5 |
311-319 |
Sentence |
denotes |
METHODS: |
T6 |
320-404 |
Sentence |
denotes |
A mixed methods approach was taken to examine fatigue in a cohort of people with AS. |
T7 |
405-477 |
Sentence |
denotes |
Fatigue levels were evaluated from 3 consecutive monthly questionnaires. |
T8 |
478-610 |
Sentence |
denotes |
Open-ended questions on fatigue were analyzed using thematic analysis and logistic regression was used to examine quantitative data. |
T9 |
611-750 |
Sentence |
denotes |
In addition, fatigue levels were examined before and after treatment with anti-tumor necrosis factor (TNF) compared to nontreated controls. |
T10 |
751-759 |
Sentence |
denotes |
RESULTS: |
T11 |
760-840 |
Sentence |
denotes |
Three hundred forty-eight of 385 participants completed a fatigue questionnaire. |
T12 |
841-926 |
Sentence |
denotes |
Fatigue was reported to have significant physical, social, and psychological effects. |
T13 |
927-1108 |
Sentence |
denotes |
A third of the participants reported that there was nothing they could do to reduce their fatigue, whereas other participants reported that medication, exercise, and resting helped. |
T14 |
1109-1173 |
Sentence |
denotes |
The main factor associated with fatigue was pain [β-coefficient: |
T15 |
1174-1187 |
Sentence |
denotes |
0.74 (95% CI: |
T16 |
1188-1257 |
Sentence |
denotes |
0.66 to 0.81)], whereas depression was much less strongly associated. |
T17 |
1258-1335 |
Sentence |
denotes |
However, these factors only explained 40% of the variation in fatigue levels. |
T18 |
1336-1460 |
Sentence |
denotes |
Starting anti-TNF therapy reduced fatigue and pain levels compared to the period of time before taking anti-TNF [difference: |
T19 |
1461-1474 |
Sentence |
denotes |
14.4 (95% CI: |
T20 |
1475-1574 |
Sentence |
denotes |
5.3 to 23.5) on a scale of 0-100] and this reduction was not seen in controls over the same period. |
T21 |
1575-1587 |
Sentence |
denotes |
CONCLUSIONS: |
T22 |
1588-1721 |
Sentence |
denotes |
Fatigue is not strongly associated with anxiety, motivation, and depression; instead the factor most associated with fatigue is pain. |
T23 |
1722-1914 |
Sentence |
denotes |
This suggests that in addition to treatments to reduce disease activity, strategies for alleviating fatigue in AS should focus on pain management techniques and actively treating inflammation. |
T1 |
0-77 |
Sentence |
denotes |
Fatigue in ankylosing spondylitis: treatment should focus on pain management. |
T2 |
78-89 |
Sentence |
denotes |
OBJECTIVES: |
T3 |
90-166 |
Sentence |
denotes |
Fatigue is an important symptom associated with ankylosing spondylitis (AS). |
T4 |
167-310 |
Sentence |
denotes |
This study examines patients' perspectives and clinical associations of fatigue to help inform potential strategies to alleviate fatigue in AS. |
T5 |
311-319 |
Sentence |
denotes |
METHODS: |
T6 |
320-404 |
Sentence |
denotes |
A mixed methods approach was taken to examine fatigue in a cohort of people with AS. |
T7 |
405-477 |
Sentence |
denotes |
Fatigue levels were evaluated from 3 consecutive monthly questionnaires. |
T8 |
478-610 |
Sentence |
denotes |
Open-ended questions on fatigue were analyzed using thematic analysis and logistic regression was used to examine quantitative data. |
T9 |
611-750 |
Sentence |
denotes |
In addition, fatigue levels were examined before and after treatment with anti-tumor necrosis factor (TNF) compared to nontreated controls. |
T10 |
751-759 |
Sentence |
denotes |
RESULTS: |
T11 |
760-840 |
Sentence |
denotes |
Three hundred forty-eight of 385 participants completed a fatigue questionnaire. |
T12 |
841-926 |
Sentence |
denotes |
Fatigue was reported to have significant physical, social, and psychological effects. |
T13 |
927-1108 |
Sentence |
denotes |
A third of the participants reported that there was nothing they could do to reduce their fatigue, whereas other participants reported that medication, exercise, and resting helped. |
T14 |
1109-1173 |
Sentence |
denotes |
The main factor associated with fatigue was pain [β-coefficient: |
T15 |
1174-1187 |
Sentence |
denotes |
0.74 (95% CI: |
T16 |
1188-1257 |
Sentence |
denotes |
0.66 to 0.81)], whereas depression was much less strongly associated. |
T17 |
1258-1335 |
Sentence |
denotes |
However, these factors only explained 40% of the variation in fatigue levels. |
T18 |
1336-1460 |
Sentence |
denotes |
Starting anti-TNF therapy reduced fatigue and pain levels compared to the period of time before taking anti-TNF [difference: |
T19 |
1461-1474 |
Sentence |
denotes |
14.4 (95% CI: |
T20 |
1475-1574 |
Sentence |
denotes |
5.3 to 23.5) on a scale of 0-100] and this reduction was not seen in controls over the same period. |
T21 |
1575-1587 |
Sentence |
denotes |
CONCLUSIONS: |
T22 |
1588-1721 |
Sentence |
denotes |
Fatigue is not strongly associated with anxiety, motivation, and depression; instead the factor most associated with fatigue is pain. |
T23 |
1722-1914 |
Sentence |
denotes |
This suggests that in addition to treatments to reduce disease activity, strategies for alleviating fatigue in AS should focus on pain management techniques and actively treating inflammation. |