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Inflammaging

Id Subject Object Predicate Lexical cue
T1 0-125 Sentence denotes Autoantibodies against galectins are associated with antiphospholipid syndrome in patients with systemic lupus erythematosus.
T2 126-263 Sentence denotes The presence of autoantibodies against immunoregulatory effectors can be relevant for onset and/or the progression of autoimmune disease.
T3 264-498 Sentence denotes Emerging insights into an immunological activity profile including a role as opsonins give reason to systematically monitor sera of patients for immunoglobulin G (IgG) autoantibodies, preferably for several galectins at the same time.
T4 499-770 Sentence denotes Here, we report on a study of chronic inflammatory rheumatic diseases, i.e. systemic lupus erythematosus (SLE; pilot cohort p, n = 40; confirmation cohort c, n = 109), rheumatoid arthritis (RA; p, n = 32; c, n = 25) and primary antiphospholipid syndrome (APS; c, n = 64).
T5 771-1004 Sentence denotes Enzyme-linked immunosorbent assay-based series using galectin-1, -2, -3, -4, -7, -8 and -9 and natural processing products, i.e. the truncated version of galectin-3 and the N-terminal domains of galectin-4, -8 and -9, were performed.
T6 1005-1112 Sentence denotes Normal healthy donors (p, n = 20; c, n = 21) and patients with paraproteins (c, n = 19) served as controls.
T7 1113-1307 Sentence denotes Highly significant optical density-value readings for IgG autoantibodies were consistently detected for the proto-type galectin-7 (SLE) and the tandem repeat-type galectin-8 and -9 (SLE and RA).
T8 1308-1480 Sentence denotes Their presence was independent from the autoantibody status against double-stranded DNA (for patients with SLE) or a rheumatoid factor (for patients with RA), respectively.
T9 1481-1685 Sentence denotes Importantly, anti-galectin-2 autoantibodies highly significantly correlated with the appearance of a secondary APS in patients with SLE so that this parameter may serve as an additional biomarker for APS.
T10 1686-1893 Sentence denotes Equally of note, the presence of IgG autoantibodies against galectins capable to act as an opsonin may contribute to a sustained immune dysregulation in patients with chronic inflammatory rheumatic diseases.
T1 0-125 Sentence denotes Autoantibodies against galectins are associated with antiphospholipid syndrome in patients with systemic lupus erythematosus.
T2 126-263 Sentence denotes The presence of autoantibodies against immunoregulatory effectors can be relevant for onset and/or the progression of autoimmune disease.
T3 264-498 Sentence denotes Emerging insights into an immunological activity profile including a role as opsonins give reason to systematically monitor sera of patients for immunoglobulin G (IgG) autoantibodies, preferably for several galectins at the same time.
T4 499-770 Sentence denotes Here, we report on a study of chronic inflammatory rheumatic diseases, i.e. systemic lupus erythematosus (SLE; pilot cohort p, n = 40; confirmation cohort c, n = 109), rheumatoid arthritis (RA; p, n = 32; c, n = 25) and primary antiphospholipid syndrome (APS; c, n = 64).
T5 771-1004 Sentence denotes Enzyme-linked immunosorbent assay-based series using galectin-1, -2, -3, -4, -7, -8 and -9 and natural processing products, i.e. the truncated version of galectin-3 and the N-terminal domains of galectin-4, -8 and -9, were performed.
T6 1005-1112 Sentence denotes Normal healthy donors (p, n = 20; c, n = 21) and patients with paraproteins (c, n = 19) served as controls.
T7 1113-1307 Sentence denotes Highly significant optical density-value readings for IgG autoantibodies were consistently detected for the proto-type galectin-7 (SLE) and the tandem repeat-type galectin-8 and -9 (SLE and RA).
T8 1308-1480 Sentence denotes Their presence was independent from the autoantibody status against double-stranded DNA (for patients with SLE) or a rheumatoid factor (for patients with RA), respectively.
T9 1481-1685 Sentence denotes Importantly, anti-galectin-2 autoantibodies highly significantly correlated with the appearance of a secondary APS in patients with SLE so that this parameter may serve as an additional biomarker for APS.
T10 1686-1893 Sentence denotes Equally of note, the presence of IgG autoantibodies against galectins capable to act as an opsonin may contribute to a sustained immune dysregulation in patients with chronic inflammatory rheumatic diseases.

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-125 Sentence denotes Autoantibodies against galectins are associated with antiphospholipid syndrome in patients with systemic lupus erythematosus.
TextSentencer_T2 126-263 Sentence denotes The presence of autoantibodies against immunoregulatory effectors can be relevant for onset and/or the progression of autoimmune disease.
TextSentencer_T3 264-498 Sentence denotes Emerging insights into an immunological activity profile including a role as opsonins give reason to systematically monitor sera of patients for immunoglobulin G (IgG) autoantibodies, preferably for several galectins at the same time.
TextSentencer_T4 499-770 Sentence denotes Here, we report on a study of chronic inflammatory rheumatic diseases, i.e. systemic lupus erythematosus (SLE; pilot cohort p, n = 40; confirmation cohort c, n = 109), rheumatoid arthritis (RA; p, n = 32; c, n = 25) and primary antiphospholipid syndrome (APS; c, n = 64).
TextSentencer_T5 771-1004 Sentence denotes Enzyme-linked immunosorbent assay-based series using galectin-1, -2, -3, -4, -7, -8 and -9 and natural processing products, i.e. the truncated version of galectin-3 and the N-terminal domains of galectin-4, -8 and -9, were performed.
TextSentencer_T6 1005-1112 Sentence denotes Normal healthy donors (p, n = 20; c, n = 21) and patients with paraproteins (c, n = 19) served as controls.
TextSentencer_T7 1113-1307 Sentence denotes Highly significant optical density-value readings for IgG autoantibodies were consistently detected for the proto-type galectin-7 (SLE) and the tandem repeat-type galectin-8 and -9 (SLE and RA).
TextSentencer_T8 1308-1480 Sentence denotes Their presence was independent from the autoantibody status against double-stranded DNA (for patients with SLE) or a rheumatoid factor (for patients with RA), respectively.
TextSentencer_T9 1481-1685 Sentence denotes Importantly, anti-galectin-2 autoantibodies highly significantly correlated with the appearance of a secondary APS in patients with SLE so that this parameter may serve as an additional biomarker for APS.
TextSentencer_T10 1686-1893 Sentence denotes Equally of note, the presence of IgG autoantibodies against galectins capable to act as an opsonin may contribute to a sustained immune dysregulation in patients with chronic inflammatory rheumatic diseases.
T1 0-125 Sentence denotes Autoantibodies against galectins are associated with antiphospholipid syndrome in patients with systemic lupus erythematosus.
T2 126-263 Sentence denotes The presence of autoantibodies against immunoregulatory effectors can be relevant for onset and/or the progression of autoimmune disease.
T3 264-498 Sentence denotes Emerging insights into an immunological activity profile including a role as opsonins give reason to systematically monitor sera of patients for immunoglobulin G (IgG) autoantibodies, preferably for several galectins at the same time.
T4 499-770 Sentence denotes Here, we report on a study of chronic inflammatory rheumatic diseases, i.e. systemic lupus erythematosus (SLE; pilot cohort p, n = 40; confirmation cohort c, n = 109), rheumatoid arthritis (RA; p, n = 32; c, n = 25) and primary antiphospholipid syndrome (APS; c, n = 64).
T5 771-1004 Sentence denotes Enzyme-linked immunosorbent assay-based series using galectin-1, -2, -3, -4, -7, -8 and -9 and natural processing products, i.e. the truncated version of galectin-3 and the N-terminal domains of galectin-4, -8 and -9, were performed.
T6 1005-1112 Sentence denotes Normal healthy donors (p, n = 20; c, n = 21) and patients with paraproteins (c, n = 19) served as controls.
T7 1113-1307 Sentence denotes Highly significant optical density-value readings for IgG autoantibodies were consistently detected for the proto-type galectin-7 (SLE) and the tandem repeat-type galectin-8 and -9 (SLE and RA).
T8 1308-1480 Sentence denotes Their presence was independent from the autoantibody status against double-stranded DNA (for patients with SLE) or a rheumatoid factor (for patients with RA), respectively.
T9 1481-1685 Sentence denotes Importantly, anti-galectin-2 autoantibodies highly significantly correlated with the appearance of a secondary APS in patients with SLE so that this parameter may serve as an additional biomarker for APS.
T10 1686-1893 Sentence denotes Equally of note, the presence of IgG autoantibodies against galectins capable to act as an opsonin may contribute to a sustained immune dysregulation in patients with chronic inflammatory rheumatic diseases.
T1 0-125 Sentence denotes Autoantibodies against galectins are associated with antiphospholipid syndrome in patients with systemic lupus erythematosus.
T2 126-263 Sentence denotes The presence of autoantibodies against immunoregulatory effectors can be relevant for onset and/or the progression of autoimmune disease.
T3 264-498 Sentence denotes Emerging insights into an immunological activity profile including a role as opsonins give reason to systematically monitor sera of patients for immunoglobulin G (IgG) autoantibodies, preferably for several galectins at the same time.
T4 499-770 Sentence denotes Here, we report on a study of chronic inflammatory rheumatic diseases, i.e. systemic lupus erythematosus (SLE; pilot cohort p, n = 40; confirmation cohort c, n = 109), rheumatoid arthritis (RA; p, n = 32; c, n = 25) and primary antiphospholipid syndrome (APS; c, n = 64).
T5 771-1004 Sentence denotes Enzyme-linked immunosorbent assay-based series using galectin-1, -2, -3, -4, -7, -8 and -9 and natural processing products, i.e. the truncated version of galectin-3 and the N-terminal domains of galectin-4, -8 and -9, were performed.
T6 1005-1112 Sentence denotes Normal healthy donors (p, n = 20; c, n = 21) and patients with paraproteins (c, n = 19) served as controls.
T7 1113-1307 Sentence denotes Highly significant optical density-value readings for IgG autoantibodies were consistently detected for the proto-type galectin-7 (SLE) and the tandem repeat-type galectin-8 and -9 (SLE and RA).
T8 1308-1480 Sentence denotes Their presence was independent from the autoantibody status against double-stranded DNA (for patients with SLE) or a rheumatoid factor (for patients with RA), respectively.
T9 1481-1685 Sentence denotes Importantly, anti-galectin-2 autoantibodies highly significantly correlated with the appearance of a secondary APS in patients with SLE so that this parameter may serve as an additional biomarker for APS.
T10 1686-1893 Sentence denotes Equally of note, the presence of IgG autoantibodies against galectins capable to act as an opsonin may contribute to a sustained immune dysregulation in patients with chronic inflammatory rheumatic diseases.

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 244-254 HP_0002960 denotes autoimmune
T2 244-262 HP_0002960 denotes autoimmune disease
T3 575-603 HP_0002725 denotes systemic lupus erythematosus
T4 667-687 HP_0001370 denotes rheumatoid arthritis
T5 678-687 HP_0001369 denotes arthritis
T6 1815-1835 HP_0002958 denotes immune dysregulation

ICD10

Id Subject Object Predicate Lexical cue
T1 96-124 http://purl.bioontology.org/ontology/ICD10/M32.9 denotes systemic lupus erythematosus
T2 575-603 http://purl.bioontology.org/ontology/ICD10/M32.9 denotes systemic lupus erythematosus
T3 96-124 http://purl.bioontology.org/ontology/ICD10/M32 denotes systemic lupus erythematosus
T4 575-603 http://purl.bioontology.org/ontology/ICD10/M32 denotes systemic lupus erythematosus
T5 105-124 http://purl.bioontology.org/ontology/ICD10/L93 denotes lupus erythematosus
T6 584-603 http://purl.bioontology.org/ontology/ICD10/L93 denotes lupus erythematosus
T7 550-559 http://purl.bioontology.org/ontology/ICD10/M79.0 denotes rheumatic
T8 1874-1883 http://purl.bioontology.org/ontology/ICD10/M79.0 denotes rheumatic
T9 667-687 http://purl.bioontology.org/ontology/ICD10/M06.9 denotes rheumatoid arthritis
T10 678-687 http://purl.bioontology.org/ontology/ICD10/M13.9 denotes arthritis

GlycoBiology-FMA

Id Subject Object Predicate Lexical cue
_T1 0-14 FMAID:167180 denotes Autoantibodies
_T2 53-69 FMAID:82779 denotes antiphospholipid
_T3 53-69 FMAID:196772 denotes antiphospholipid
_T4 142-156 FMAID:167180 denotes autoantibodies
_T5 409-423 FMAID:167177 denotes immunoglobulin
_T6 409-423 FMAID:62871 denotes immunoglobulin
_T7 409-425 FMAID:167178 denotes immunoglobulin G
_T8 409-425 FMAID:62872 denotes immunoglobulin G
_T9 409-425 FMAID:167185 denotes immunoglobulin G
_T10 409-425 FMAID:62875 denotes immunoglobulin G
_T11 409-425 FMAID:167181 denotes immunoglobulin G
_T12 409-425 FMAID:62873 denotes immunoglobulin G
_T13 409-425 FMAID:62874 denotes immunoglobulin G
_T14 409-425 FMAID:62876 denotes immunoglobulin G
_T15 409-425 FMAID:167187 denotes immunoglobulin G
_T16 409-425 FMAID:167183 denotes immunoglobulin G
_T17 427-430 FMAID:167179 denotes IgG
_T18 432-446 FMAID:167180 denotes autoantibodies
_T19 727-743 FMAID:196772 denotes antiphospholipid
_T20 727-743 FMAID:82779 denotes antiphospholipid
_T21 1167-1170 FMAID:167179 denotes IgG
_T22 1171-1185 FMAID:167180 denotes autoantibodies
_T23 1348-1360 FMAID:167180 denotes autoantibody
_T24 1510-1524 FMAID:167180 denotes autoantibodies
_T25 1719-1722 FMAID:167179 denotes IgG
_T26 1723-1737 FMAID:167180 denotes autoantibodies

uniprot-human

Id Subject Object Predicate Lexical cue
T1 754-757 http://www.uniprot.org/uniprot/P07288 denotes APS
T2 1592-1595 http://www.uniprot.org/uniprot/P07288 denotes APS
T3 1681-1684 http://www.uniprot.org/uniprot/P07288 denotes APS
T4 754-757 http://www.uniprot.org/uniprot/O14492 denotes APS
T5 1592-1595 http://www.uniprot.org/uniprot/O14492 denotes APS
T6 1681-1684 http://www.uniprot.org/uniprot/O14492 denotes APS
T7 824-834 http://www.uniprot.org/uniprot/P09382 denotes galectin-1
T8 925-935 http://www.uniprot.org/uniprot/P17931 denotes galectin-3
T9 966-976 http://www.uniprot.org/uniprot/P56470 denotes galectin-4
T10 1232-1242 http://www.uniprot.org/uniprot/P47929 denotes galectin-7
T11 1276-1286 http://www.uniprot.org/uniprot/Q9H585 denotes galectin-8
T12 1425-1442 http://www.uniprot.org/uniprot/P04207 denotes rheumatoid factor
T13 1425-1442 http://www.uniprot.org/uniprot/P04206 denotes rheumatoid factor
T14 1499-1509 http://www.uniprot.org/uniprot/P05162 denotes galectin-2

uniprot-mouse

Id Subject Object Predicate Lexical cue
T1 824-834 http://www.uniprot.org/uniprot/P16045 denotes galectin-1
T2 925-935 http://www.uniprot.org/uniprot/P16110 denotes galectin-3
T3 966-976 http://www.uniprot.org/uniprot/Q8K419 denotes galectin-4
T4 1232-1242 http://www.uniprot.org/uniprot/O54974 denotes galectin-7
T5 1276-1286 http://www.uniprot.org/uniprot/Q9JL15 denotes galectin-8
T6 1499-1509 http://www.uniprot.org/uniprot/Q9CQW5 denotes galectin-2

GlycoBiology-NCBITAXON

Id Subject Object Predicate Lexical cue
T1 667-677 http://purl.bioontology.org/ontology/NCBITAXON/572355 denotes rheumatoid
T2 1425-1435 http://purl.bioontology.org/ontology/NCBITAXON/572355 denotes rheumatoid

GO-BP

Id Subject Object Predicate Lexical cue
T1 388-392 http://purl.obolibrary.org/obo/GO_0004617 denotes sera

GO-MF

Id Subject Object Predicate Lexical cue
T1 409-423 http://purl.obolibrary.org/obo/GO_0003823 denotes immunoglobulin

EDAM-topics

Id Subject Object Predicate Lexical cue
T1 255-262 http://edamontology.org/topic_0634 denotes disease
T2 290-303 http://edamontology.org/topic_0804 denotes immunological
T3 520-525 http://edamontology.org/topic_3678 denotes study
T4 560-568 http://edamontology.org/topic_0634 denotes diseases
T5 946-954 http://edamontology.org/topic_0749 denotes terminal
T6 1667-1676 http://edamontology.org/topic_3360 denotes biomarker
T7 1884-1892 http://edamontology.org/topic_0634 denotes diseases

EDAM-DFO

Id Subject Object Predicate Lexical cue
T1 508-514 http://edamontology.org/data_2048 denotes report
T2 874-884 http://edamontology.org/operation_0004 denotes processing
T3 874-884 http://edamontology.org/operation_2409 denotes processing
T4 1005-1011 http://edamontology.org/operation_3435 denotes Normal
T5 1204-1212 http://edamontology.org/operation_2423 denotes detected
T6 1383-1391 http://edamontology.org/data_0853 denotes stranded
T7 1546-1556 http://edamontology.org/operation_3465 denotes correlated
T8 1630-1639 http://edamontology.org/data_2527 denotes parameter

Allie

Id Subject Object Predicate Lexical cue
SS1_22887862_2_0 409-425 expanded denotes immunoglobulin G
SS2_22887862_2_0 427-430 abbr denotes IgG
SS1_22887862_3_0 575-603 expanded denotes systemic lupus erythematosus
SS2_22887862_3_0 605-608 abbr denotes SLE
SS1_22887862_3_1 667-687 expanded denotes rheumatoid arthritis
SS2_22887862_3_1 689-691 abbr denotes RA
SS1_22887862_3_2 727-752 expanded denotes antiphospholipid syndrome
SS2_22887862_3_2 754-757 abbr denotes APS
AE1_22887862_2_0 SS1_22887862_2_0 SS2_22887862_2_0 abbreviatedTo immunoglobulin G,IgG
AE1_22887862_3_0 SS1_22887862_3_0 SS2_22887862_3_0 abbreviatedTo systemic lupus erythematosus,SLE
AE1_22887862_3_1 SS1_22887862_3_1 SS2_22887862_3_1 abbreviatedTo rheumatoid arthritis,RA
AE1_22887862_3_2 SS1_22887862_3_2 SS2_22887862_3_2 abbreviatedTo antiphospholipid syndrome,APS

Lectin

Id Subject Object Predicate Lexical cue
Lectin_T1 966-976 https://acgg.asia/db/lfdb/LfDB0272 denotes galectin-4
Lectin_T2 824-834 https://acgg.asia/db/lfdb/LfDB0270 denotes galectin-1
Lectin_T3 824-834 https://acgg.asia/db/lfdb/LfDB0057 denotes galectin-1

mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 53-78 Disease denotes antiphospholipid syndrome http://purl.obolibrary.org/obo/MONDO_0007140
T2 96-124 Disease denotes systemic lupus erythematosus http://purl.obolibrary.org/obo/MONDO_0007915
T3 244-262 Disease denotes autoimmune disease http://purl.obolibrary.org/obo/MONDO_0007179
T4 550-568 Disease denotes rheumatic diseases http://purl.obolibrary.org/obo/MONDO_0005554
T5 575-603 Disease denotes systemic lupus erythematosus http://purl.obolibrary.org/obo/MONDO_0007915
T6 605-608 Disease denotes SLE http://purl.obolibrary.org/obo/MONDO_0007915
T7 667-687 Disease denotes rheumatoid arthritis http://purl.obolibrary.org/obo/MONDO_0008383
T8 719-752 Disease denotes primary antiphospholipid syndrome http://purl.obolibrary.org/obo/MONDO_0005204
T9 754-757 Disease denotes APS http://purl.obolibrary.org/obo/MONDO_0017278
T10 1244-1247 Disease denotes SLE http://purl.obolibrary.org/obo/MONDO_0007915
T11 1295-1298 Disease denotes SLE http://purl.obolibrary.org/obo/MONDO_0007915
T12 1415-1418 Disease denotes SLE http://purl.obolibrary.org/obo/MONDO_0007915
T13 1592-1595 Disease denotes APS http://purl.obolibrary.org/obo/MONDO_0017278
T14 1613-1616 Disease denotes SLE http://purl.obolibrary.org/obo/MONDO_0007915
T15 1681-1684 Disease denotes APS http://purl.obolibrary.org/obo/MONDO_0017278
T16 1874-1892 Disease denotes rheumatic diseases http://purl.obolibrary.org/obo/MONDO_0005554

HP-phenotype

Id Subject Object Predicate Lexical cue hp_id
T1 96-124 Phenotype denotes systemic lupus erythematosus HP:0002725
T2 244-262 Phenotype denotes autoimmune disease HP:0002960
T3 575-603 Phenotype denotes systemic lupus erythematosus HP:0002725
T4 605-608 Phenotype denotes SLE HP:0002725
T5 667-687 Phenotype denotes rheumatoid arthritis HP:0001370
T6 689-691 Phenotype denotes RA HP:0001370
T7 1244-1247 Phenotype denotes SLE HP:0002725
T8 1295-1298 Phenotype denotes SLE HP:0002725
T9 1303-1305 Phenotype denotes RA HP:0001370
T10 1415-1418 Phenotype denotes SLE HP:0002725
T11 1462-1464 Phenotype denotes RA HP:0001370
T12 1613-1616 Phenotype denotes SLE HP:0002725
T13 1815-1835 Phenotype denotes immune dysregulation HP:0002958