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Inflammaging

Id Subject Object Predicate Lexical cue
T1 0-86 Sentence denotes Interactions of miR-34b/c and TP53 polymorphisms on the risk of intracranial aneurysm.
T2 87-229 Sentence denotes Several lines of evidence indicate that inflammatory processes play a key role in the happening and development of intracranial aneurysm (IA).
T3 230-342 Sentence denotes Recently, polymorphisms in the TP53 gene were shown to be associated with inflammation and inflammatory disease.
T4 343-489 Sentence denotes The aim of this study was to investigate the interactions of miR-34b/c and TP53 Arg72-Pro polymorphisms on the risk of IA in a Chinese population.
T5 490-595 Sentence denotes A total of 590 individuals (including 164 patients with IA and 426 controls) were involved in this study.
T6 596-771 Sentence denotes The polymorphisms (i.e., miR-34b/c rs4938723 and TP53 Arg72-Pro) were genotyped by polymerase chain reaction-restriction fragment length polymorphism assay and DNA sequencing.
T7 772-912 Sentence denotes We found that the CC genotype of miR-34b/c rs4938723 was significantly associated with a decreased risk of IA compared with the TT genotype.
T8 913-1174 Sentence denotes Moreover, a significant gene interaction of the carriers with the combined genotypes of miR-34b/c rs4938723CC and TP53 Arg72Pro CG/CC/GG had a decreased risk of IA, compared with those carrying miR-34b/c rs4938723CT/TT+TP53 Arg72Pro GG/CG/CC combined genotypes.
T9 1175-1306 Sentence denotes These findings suggest that the miR-34b/c rs4938723CC and TP53 Arg72-Pro polymorphisms may be involved in the susceptibility to IA.
T1 0-86 Sentence denotes Interactions of miR-34b/c and TP53 polymorphisms on the risk of intracranial aneurysm.
T2 87-229 Sentence denotes Several lines of evidence indicate that inflammatory processes play a key role in the happening and development of intracranial aneurysm (IA).
T3 230-342 Sentence denotes Recently, polymorphisms in the TP53 gene were shown to be associated with inflammation and inflammatory disease.
T4 343-489 Sentence denotes The aim of this study was to investigate the interactions of miR-34b/c and TP53 Arg72-Pro polymorphisms on the risk of IA in a Chinese population.
T5 490-595 Sentence denotes A total of 590 individuals (including 164 patients with IA and 426 controls) were involved in this study.
T6 596-771 Sentence denotes The polymorphisms (i.e., miR-34b/c rs4938723 and TP53 Arg72-Pro) were genotyped by polymerase chain reaction-restriction fragment length polymorphism assay and DNA sequencing.
T7 772-912 Sentence denotes We found that the CC genotype of miR-34b/c rs4938723 was significantly associated with a decreased risk of IA compared with the TT genotype.
T8 913-1174 Sentence denotes Moreover, a significant gene interaction of the carriers with the combined genotypes of miR-34b/c rs4938723CC and TP53 Arg72Pro CG/CC/GG had a decreased risk of IA, compared with those carrying miR-34b/c rs4938723CT/TT+TP53 Arg72Pro GG/CG/CC combined genotypes.
T9 1175-1306 Sentence denotes These findings suggest that the miR-34b/c rs4938723CC and TP53 Arg72-Pro polymorphisms may be involved in the susceptibility to IA.

DisGeNET

Id Subject Object Predicate Lexical cue
T0 1233-1237 gene:7157 denotes TP53
T1 1303-1305 disease:C0007766 denotes IA
R1 T0 T1 associated_with TP53,IA

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 202-223 HP_0004944 denotes intracranial aneurysm
T2 215-223 HP_0002617 denotes aneurysm

Allie

Id Subject Object Predicate Lexical cue
SS1_22844323_1_0 202-223 expanded denotes intracranial aneurysm
SS2_22844323_1_0 225-227 abbr denotes IA
AE1_22844323_1_0 SS1_22844323_1_0 SS2_22844323_1_0 abbreviatedTo intracranial aneurysm,IA

DisGeNET5_variant_disease

Id Subject Object Predicate Lexical cue
22844323-6#43#52#geners4938723 815-824 geners4938723 denotes rs4938723
22844323-6#107#109#diseaseC0007766 879-881 diseaseC0007766 denotes IA
22844323-6#107#109#diseaseC1290398 879-881 diseaseC1290398 denotes IA
22844323-8#63#72#geners11540654 1238-1247 geners11540654 denotes Arg72-Pro
22844323-8#128#130#diseaseC0007766 1303-1305 diseaseC0007766 denotes IA
22844323-8#128#130#diseaseC1290398 1303-1305 diseaseC1290398 denotes IA
43#52#geners4938723107#109#diseaseC0007766 22844323-6#43#52#geners4938723 22844323-6#107#109#diseaseC0007766 associated_with rs4938723,IA
43#52#geners4938723107#109#diseaseC1290398 22844323-6#43#52#geners4938723 22844323-6#107#109#diseaseC1290398 associated_with rs4938723,IA
63#72#geners11540654128#130#diseaseC0007766 22844323-8#63#72#geners11540654 22844323-8#128#130#diseaseC0007766 associated_with Arg72-Pro,IA
63#72#geners11540654128#130#diseaseC1290398 22844323-8#63#72#geners11540654 22844323-8#128#130#diseaseC1290398 associated_with Arg72-Pro,IA

DisGeNET5_gene_disease

Id Subject Object Predicate Lexical cue
22844323-0#16#23#gene407041 404-411 gene407041 denotes miR-34b
22844323-0#30#34#gene7157 418-422 gene7157 denotes TP53
22844323-0#64#85#diseaseC0007766 465-885 diseaseC0007766 denotes in a Chinese population. A total of 590 individuals (including 164 patients with IA and 426 controls) were involved in this study. The polymorphisms (i.e., miR-34b/c rs4938723 and TP53 Arg72-Pro) were genotyped by polymerase chain reaction-restriction fragment length polymorphism assay and DNA sequencing. We found that the CC genotype of miR-34b/c rs4938723 was significantly associated with a decreased risk of IA com
22844323-0#64#85#diseaseC1290398 465-885 diseaseC1290398 denotes in a Chinese population. A total of 590 individuals (including 164 patients with IA and 426 controls) were involved in this study. The polymorphisms (i.e., miR-34b/c rs4938723 and TP53 Arg72-Pro) were genotyped by polymerase chain reaction-restriction fragment length polymorphism assay and DNA sequencing. We found that the CC genotype of miR-34b/c rs4938723 was significantly associated with a decreased risk of IA com
22844323-0#64#85#diseaseC0007766 465-885 diseaseC0007766 denotes in a Chinese population. A total of 590 individuals (including 164 patients with IA and 426 controls) were involved in this study. The polymorphisms (i.e., miR-34b/c rs4938723 and TP53 Arg72-Pro) were genotyped by polymerase chain reaction-restriction fragment length polymorphism assay and DNA sequencing. We found that the CC genotype of miR-34b/c rs4938723 was significantly associated with a decreased risk of IA com
22844323-0#64#85#diseaseC1290398 465-885 diseaseC1290398 denotes in a Chinese population. A total of 590 individuals (including 164 patients with IA and 426 controls) were involved in this study. The polymorphisms (i.e., miR-34b/c rs4938723 and TP53 Arg72-Pro) were genotyped by polymerase chain reaction-restriction fragment length polymorphism assay and DNA sequencing. We found that the CC genotype of miR-34b/c rs4938723 was significantly associated with a decreased risk of IA com
22844323-2#31#35#gene7157 261-265 gene7157 denotes TP53
22844323-2#91#111#diseaseC1290884 321-341 diseaseC1290884 denotes inflammatory disease
16#23#gene40704164#85#diseaseC0007766 22844323-0#16#23#gene407041 22844323-0#64#85#diseaseC0007766 associated_with miR-34b,"in a Chinese population. A total of 590 individuals (including 164 patients with IA and 426 controls) were involved in this study. The polymorphisms (i.e., miR-34b/c rs4938723 and TP53 Arg72-Pro) were genotyped by polymerase chain reaction-restriction fragment length polymorphism assay and DNA sequencing. We found that the CC genotype of miR-34b/c rs4938723 was significantly associated with a decreased risk of IA com"
16#23#gene40704164#85#diseaseC1290398 22844323-0#16#23#gene407041 22844323-0#64#85#diseaseC1290398 associated_with miR-34b,"in a Chinese population. A total of 590 individuals (including 164 patients with IA and 426 controls) were involved in this study. The polymorphisms (i.e., miR-34b/c rs4938723 and TP53 Arg72-Pro) were genotyped by polymerase chain reaction-restriction fragment length polymorphism assay and DNA sequencing. We found that the CC genotype of miR-34b/c rs4938723 was significantly associated with a decreased risk of IA com"
16#23#gene40704164#85#diseaseC0007766 22844323-0#16#23#gene407041 22844323-0#64#85#diseaseC0007766 associated_with miR-34b,"in a Chinese population. A total of 590 individuals (including 164 patients with IA and 426 controls) were involved in this study. The polymorphisms (i.e., miR-34b/c rs4938723 and TP53 Arg72-Pro) were genotyped by polymerase chain reaction-restriction fragment length polymorphism assay and DNA sequencing. We found that the CC genotype of miR-34b/c rs4938723 was significantly associated with a decreased risk of IA com"
16#23#gene40704164#85#diseaseC1290398 22844323-0#16#23#gene407041 22844323-0#64#85#diseaseC1290398 associated_with miR-34b,"in a Chinese population. A total of 590 individuals (including 164 patients with IA and 426 controls) were involved in this study. The polymorphisms (i.e., miR-34b/c rs4938723 and TP53 Arg72-Pro) were genotyped by polymerase chain reaction-restriction fragment length polymorphism assay and DNA sequencing. We found that the CC genotype of miR-34b/c rs4938723 was significantly associated with a decreased risk of IA com"
30#34#gene715764#85#diseaseC0007766 22844323-0#30#34#gene7157 22844323-0#64#85#diseaseC0007766 associated_with TP53,"in a Chinese population. A total of 590 individuals (including 164 patients with IA and 426 controls) were involved in this study. The polymorphisms (i.e., miR-34b/c rs4938723 and TP53 Arg72-Pro) were genotyped by polymerase chain reaction-restriction fragment length polymorphism assay and DNA sequencing. We found that the CC genotype of miR-34b/c rs4938723 was significantly associated with a decreased risk of IA com"
30#34#gene715764#85#diseaseC1290398 22844323-0#30#34#gene7157 22844323-0#64#85#diseaseC1290398 associated_with TP53,"in a Chinese population. A total of 590 individuals (including 164 patients with IA and 426 controls) were involved in this study. The polymorphisms (i.e., miR-34b/c rs4938723 and TP53 Arg72-Pro) were genotyped by polymerase chain reaction-restriction fragment length polymorphism assay and DNA sequencing. We found that the CC genotype of miR-34b/c rs4938723 was significantly associated with a decreased risk of IA com"
30#34#gene715764#85#diseaseC0007766 22844323-0#30#34#gene7157 22844323-0#64#85#diseaseC0007766 associated_with TP53,"in a Chinese population. A total of 590 individuals (including 164 patients with IA and 426 controls) were involved in this study. The polymorphisms (i.e., miR-34b/c rs4938723 and TP53 Arg72-Pro) were genotyped by polymerase chain reaction-restriction fragment length polymorphism assay and DNA sequencing. We found that the CC genotype of miR-34b/c rs4938723 was significantly associated with a decreased risk of IA com"
30#34#gene715764#85#diseaseC1290398 22844323-0#30#34#gene7157 22844323-0#64#85#diseaseC1290398 associated_with TP53,"in a Chinese population. A total of 590 individuals (including 164 patients with IA and 426 controls) were involved in this study. The polymorphisms (i.e., miR-34b/c rs4938723 and TP53 Arg72-Pro) were genotyped by polymerase chain reaction-restriction fragment length polymorphism assay and DNA sequencing. We found that the CC genotype of miR-34b/c rs4938723 was significantly associated with a decreased risk of IA com"
31#35#gene715791#111#diseaseC1290884 22844323-2#31#35#gene7157 22844323-2#91#111#diseaseC1290884 associated_with TP53,inflammatory disease