PubMed:22798143
Annnotations
GlyCosmos6-UBERON
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 97-119 | Body_part | denotes | pluripotent stem cells |
| T2 | 479-483 | Body_part | denotes | cell |
| T3 | 605-627 | Body_part | denotes | pluripotent stem cells |
| T4 | 669-680 | Body_part | denotes | fibroblasts |
| T5 | 870-874 | Body_part | denotes | cell |
| T6 | 1070-1081 | Body_part | denotes | fibroblasts |
| T7 | 1095-1105 | Body_part | denotes | stem cells |
| T8 | 1249-1271 | Body_part | denotes | pluripotent stem cells |
| T9 | 1286-1297 | Body_part | denotes | fibroblasts |
| T10 | 1311-1321 | Body_part | denotes | stem cells |
| T11 | 1744-1750 | Body_part | denotes | system |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| PD-NCBITaxon-B_T1 | 279-284 | http://purl.bioontology.org/ontology/NCBITAXON/4932 | denotes | yeast | |
| T1 | 575-580 | OrganismTaxon | denotes | human | NCBItxid:9606 |
| T2 | 661-668 | OrganismTaxon | denotes | patient | NCBItxid:9606 |
GlyCosmos600-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 109-119 | http://purl.obolibrary.org/obo/CL_0000034 | denotes | stem cells |
| T2 | 479-483 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T3 | 617-627 | http://purl.obolibrary.org/obo/CL_0000034 | denotes | stem cells |
| T4 | 669-680 | http://purl.obolibrary.org/obo/CL_0000057 | denotes | fibroblasts |
| T5 | 771-776 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T6 | 870-874 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T7 | 1070-1081 | http://purl.obolibrary.org/obo/CL_0000057 | denotes | fibroblasts |
| T8 | 1086-1105 | http://purl.obolibrary.org/obo/CL_0000047 | denotes | neuronal stem cells |
| T9 | 1261-1271 | http://purl.obolibrary.org/obo/CL_0000034 | denotes | stem cells |
| T10 | 1286-1297 | http://purl.obolibrary.org/obo/CL_0000057 | denotes | fibroblasts |
| T11 | 1302-1321 | http://purl.obolibrary.org/obo/CL_0000047 | denotes | neuronal stem cells |
| T12 | 1681-1696 | http://purl.obolibrary.org/obo/CL_0002321 | denotes | embryonic cells |
PubMed_ArguminSci
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 121-269 | DRI_Approach | denotes | The genetic mutation in Friedreich ataxia (FRDA) is a hyperexpansion of the triplet-repeat sequence GAA·TTC within the first intron of the FXN gene. |
| T2 | 270-318 | DRI_Background | denotes | Although yeast and reporter construct models for |
| T3 | 342-588 | DRI_Background | denotes | expansion have been reported, studies on FRDA pathogenesis and therapeutic development are limited by the availability of an appropriate cell model in which to study the mechanism of instability of the GAA·TTC triplet repeats in the human genome. |
| T4 | 589-764 | DRI_Background | denotes | Herein, induced pluripotent stem cells (iPSCs) were generated from FRDA patient fibroblasts after transduction with the four transcription factors Oct4, Sox2, Klf4, and c-Myc. |
| T5 | 765-890 | DRI_Background | denotes | These cells were differentiated into neurospheres and neuronal precursors in vitro, providing a valuable cell model for FRDA. |
| T6 | 891-1016 | DRI_Approach | denotes | During propagation of the iPSCs, GAA·TTC triplet repeats expanded at a rate of about two GAA·TTC triplet repeats/replication. |
| T7 | 1017-1106 | DRI_Approach | denotes | However, GAA·TTC triplet repeats were stable in FRDA fibroblasts and neuronal stem cells. |
| T8 | 1107-1348 | DRI_Background | denotes | The mismatch repair enzymes MSH2, MSH3, and MSH6, implicated in repeat instability in other triplet-repeat diseases, were highly expressed in pluripotent stem cells compared with fibroblasts and neuronal stem cells and occupied FXN intron 1. |
| T9 | 1349-1402 | DRI_Background | denotes | In addition, shRNA silencing of MSH2 and MSH6 impeded |
| T10 | 1426-1436 | DRI_Background | denotes | expansion. |
| T11 | 1437-1485 | DRI_Approach | denotes | A specific pyrrole-imidazole polyamide targeting |
| T12 | 1509-1599 | DRI_Approach | denotes | DNA partially blocked repeat expansion by displacing MSH2 from FXN intron 1 in FRDA iPSCs. |
| T13 | 1600-1635 | DRI_Challenge | denotes | These studies suggest that in FRDA, |
| T14 | 1659-1751 | DRI_Challenge | denotes | instability occurs in embryonic cells and involves the highly active mismatch repair system. |
Glycosmos6-MAT
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 109-119 | http://purl.obolibrary.org/obo/MAT_0000185 | denotes | stem cells |
| T2 | 109-113 | http://purl.obolibrary.org/obo/MAT_0000239 | denotes | stem |
| T3 | 617-627 | http://purl.obolibrary.org/obo/MAT_0000185 | denotes | stem cells |
| T4 | 617-621 | http://purl.obolibrary.org/obo/MAT_0000239 | denotes | stem |
| T5 | 1095-1105 | http://purl.obolibrary.org/obo/MAT_0000185 | denotes | stem cells |
| T6 | 1095-1099 | http://purl.obolibrary.org/obo/MAT_0000239 | denotes | stem |
| T7 | 1261-1271 | http://purl.obolibrary.org/obo/MAT_0000185 | denotes | stem cells |
| T8 | 1261-1265 | http://purl.obolibrary.org/obo/MAT_0000239 | denotes | stem |
| T9 | 1311-1321 | http://purl.obolibrary.org/obo/MAT_0000185 | denotes | stem cells |
| T10 | 1311-1315 | http://purl.obolibrary.org/obo/MAT_0000239 | denotes | stem |
GlyCosmos6-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 109-119 | http://purl.obolibrary.org/obo/CL_0000034 | denotes | stem cells |
| T2 | 114-119 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T3 | 479-483 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T4 | 617-627 | http://purl.obolibrary.org/obo/CL_0000034 | denotes | stem cells |
| T5 | 622-627 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T6 | 669-680 | http://purl.obolibrary.org/obo/CL_0000057 | denotes | fibroblasts |
| T7 | 771-776 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T8 | 870-874 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T9 | 1070-1081 | http://purl.obolibrary.org/obo/CL_0000057 | denotes | fibroblasts |
| T10 | 1086-1105 | http://purl.obolibrary.org/obo/CL_0000047 | denotes | neuronal stem cells |
| T11 | 1100-1105 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T12 | 1261-1271 | http://purl.obolibrary.org/obo/CL_0000034 | denotes | stem cells |
| T13 | 1266-1271 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T14 | 1286-1297 | http://purl.obolibrary.org/obo/CL_0000057 | denotes | fibroblasts |
| T15 | 1302-1321 | http://purl.obolibrary.org/obo/CL_0000047 | denotes | neuronal stem cells |
| T16 | 1316-1321 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T17 | 1681-1696 | http://purl.obolibrary.org/obo/CL_0002321 | denotes | embryonic cells |
| T18 | 1691-1696 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T19 | 1721-1727 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | active |
DisGeNET
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T0 | 1562-1566 | gene:4436 | denotes | MSH2 |
| T1 | 1588-1592 | disease:C0016719 | denotes | FRDA |
| T2 | 1572-1575 | gene:2395 | denotes | FXN |
| T3 | 1588-1592 | disease:C0016719 | denotes | FRDA |
| R1 | T0 | T1 | associated_with | MSH2,FRDA |
| R2 | T2 | T3 | associated_with | FXN,FRDA |
PubmedHPO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 156-162 | HP_0001251 | denotes | ataxia |
Allie
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| SS1_22798143_1_0 | 145-162 | expanded | denotes | Friedreich ataxia |
| SS2_22798143_1_0 | 164-168 | abbr | denotes | FRDA |
| SS1_22798143_3_0 | 597-627 | expanded | denotes | induced pluripotent stem cells |
| SS2_22798143_3_0 | 629-634 | abbr | denotes | iPSCs |
| AE1_22798143_1_0 | SS1_22798143_1_0 | SS2_22798143_1_0 | abbreviatedTo | Friedreich ataxia,FRDA |
| AE1_22798143_3_0 | SS1_22798143_3_0 | SS2_22798143_3_0 | abbreviatedTo | induced pluripotent stem cells,iPSCs |
GlyCosmos600-FMA
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| PD-FMA-PAE-B_T1 | 97-119 | http://purl.org/sig/ont/fma/fma70570 | denotes | pluripotent stem cells |
| PD-FMA-PAE-B_T2 | 109-119 | http://purl.org/sig/ont/fma/fma63368 | denotes | stem cells |
| PD-FMA-PAE-B_T3 | 114-119 | http://purl.org/sig/ont/fma/fma68646 | denotes | cells |
| PD-FMA-PAE-B_T4 | 246-252 | http://purl.org/sig/ont/fma/fma84121 | denotes | intron |
| PD-FMA-PAE-B_T5 | 264-268 | http://purl.org/sig/ont/fma/fma74402 | denotes | gene |
| PD-FMA-PAE-B_T6 | 479-483 | http://purl.org/sig/ont/fma/fma68646 | denotes | cell |
| PD-FMA-PAE-B_T7 | 581-587 | http://purl.org/sig/ont/fma/fma84116 | denotes | genome |
| PD-FMA-PAE-B_T8 | 605-627 | http://purl.org/sig/ont/fma/fma70570 | denotes | pluripotent stem cells |
| PD-FMA-PAE-B_T9 | 617-627 | http://purl.org/sig/ont/fma/fma63368 | denotes | stem cells |
| PD-FMA-PAE-B_T10 | 622-627 | http://purl.org/sig/ont/fma/fma68646 | denotes | cells |
| PD-FMA-PAE-B_T11 | 669-680 | http://purl.org/sig/ont/fma/fma63877 | denotes | fibroblasts |
| PD-FMA-PAE-B_T12 | 771-776 | http://purl.org/sig/ont/fma/fma68646 | denotes | cells |
| PD-FMA-PAE-B_T13 | 819-827 | http://purl.org/sig/ont/fma/fma54527 | denotes | neuronal |
| PD-FMA-PAE-B_T14 | 870-874 | http://purl.org/sig/ont/fma/fma68646 | denotes | cell |
| PD-FMA-PAE-B_T15 | 1070-1081 | http://purl.org/sig/ont/fma/fma63877 | denotes | fibroblasts |
| PD-FMA-PAE-B_T16 | 1086-1094 | http://purl.org/sig/ont/fma/fma54527 | denotes | neuronal |
| PD-FMA-PAE-B_T17 | 1095-1105 | http://purl.org/sig/ont/fma/fma63368 | denotes | stem cells |
| PD-FMA-PAE-B_T18 | 1100-1105 | http://purl.org/sig/ont/fma/fma68646 | denotes | cells |
| PD-FMA-PAE-B_T19 | 1249-1271 | http://purl.org/sig/ont/fma/fma70570 | denotes | pluripotent stem cells |
| PD-FMA-PAE-B_T20 | 1261-1271 | http://purl.org/sig/ont/fma/fma63368 | denotes | stem cells |
| PD-FMA-PAE-B_T21 | 1266-1271 | http://purl.org/sig/ont/fma/fma68646 | denotes | cells |
| PD-FMA-PAE-B_T22 | 1286-1297 | http://purl.org/sig/ont/fma/fma63877 | denotes | fibroblasts |
| PD-FMA-PAE-B_T23 | 1302-1310 | http://purl.org/sig/ont/fma/fma54527 | denotes | neuronal |
| PD-FMA-PAE-B_T24 | 1311-1321 | http://purl.org/sig/ont/fma/fma63368 | denotes | stem cells |
| PD-FMA-PAE-B_T25 | 1316-1321 | http://purl.org/sig/ont/fma/fma68646 | denotes | cells |
| PD-FMA-PAE-B_T26 | 1339-1345 | http://purl.org/sig/ont/fma/fma84121 | denotes | intron |
| PD-FMA-PAE-B_T27 | 1509-1512 | http://purl.org/sig/ont/fma/fma74412 | denotes | DNA |
| PD-FMA-PAE-B_T28 | 1576-1582 | http://purl.org/sig/ont/fma/fma84121 | denotes | intron |
| PD-FMA-PAE-B_T29 | 1681-1696 | http://purl.org/sig/ont/fma/fma82840 | denotes | embryonic cells |
| PD-FMA-PAE-B_T30 | 1691-1696 | http://purl.org/sig/ont/fma/fma68646 | denotes | cells |
mondo_disease
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| PD-MONDO-B_T1 | 71-88 | http://purl.obolibrary.org/obo/MONDO_0009245 | denotes | Friedreich ataxia | |
| PD-MONDO-B_T2 | 82-88 | http://purl.obolibrary.org/obo/MONDO_0000437 | denotes | ataxia | |
| PD-MONDO-B_T3 | 145-162 | http://purl.obolibrary.org/obo/MONDO_0009245 | denotes | Friedreich ataxia | |
| PD-MONDO-B_T4 | 156-162 | http://purl.obolibrary.org/obo/MONDO_0000437 | denotes | ataxia | |
| PD-MONDO-B_T5 | 164-168 | http://purl.obolibrary.org/obo/MONDO_0009245 | denotes | FRDA | |
| PD-MONDO-B_T6 | 383-387 | http://purl.obolibrary.org/obo/MONDO_0009245 | denotes | FRDA | |
| PD-MONDO-B_T7 | 656-660 | http://purl.obolibrary.org/obo/MONDO_0009245 | denotes | FRDA | |
| PD-MONDO-B_T8 | 885-889 | http://purl.obolibrary.org/obo/MONDO_0009245 | denotes | FRDA | |
| PD-MONDO-B_T9 | 1065-1069 | http://purl.obolibrary.org/obo/MONDO_0009245 | denotes | FRDA | |
| PD-MONDO-B_T10 | 1588-1592 | http://purl.obolibrary.org/obo/MONDO_0009245 | denotes | FRDA | |
| PD-MONDO-B_T11 | 1630-1634 | http://purl.obolibrary.org/obo/MONDO_0009245 | denotes | FRDA | |
| T1 | 71-88 | Disease | denotes | Friedreich ataxia | http://purl.obolibrary.org/obo/MONDO_0009245 |
| T2 | 145-162 | Disease | denotes | Friedreich ataxia | http://purl.obolibrary.org/obo/MONDO_0009245 |
| T3 | 164-168 | Disease | denotes | FRDA | http://purl.obolibrary.org/obo/MONDO_0009245 |
| T4 | 383-387 | Disease | denotes | FRDA | http://purl.obolibrary.org/obo/MONDO_0009245 |
| T5 | 656-660 | Disease | denotes | FRDA | http://purl.obolibrary.org/obo/MONDO_0009245 |
| T6 | 885-889 | Disease | denotes | FRDA | http://purl.obolibrary.org/obo/MONDO_0009245 |
| T7 | 1065-1069 | Disease | denotes | FRDA | http://purl.obolibrary.org/obo/MONDO_0009245 |
| T8 | 1588-1592 | Disease | denotes | FRDA | http://purl.obolibrary.org/obo/MONDO_0009245 |
| T9 | 1630-1634 | Disease | denotes | FRDA | http://purl.obolibrary.org/obo/MONDO_0009245 |
DisGeNET5_gene_disease
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 22798143-0#35#38#gene2548 | 35-38 | gene2548 | denotes | GAA |
| 22798143-0#71#88#diseaseC0016719 | 71-88 | diseaseC0016719 | denotes | Friedreich ataxia |
| 22798143-1#139#142#gene2395 | 260-263 | gene2395 | denotes | FXN |
| 22798143-1#24#41#diseaseC0016719 | 145-162 | diseaseC0016719 | denotes | Friedreich ataxia |
| 22798143-3#147#151#gene5460 | 736-740 | gene5460 | denotes | Oct4 |
| 22798143-3#67#71#diseaseC1856689 | 656-660 | diseaseC1856689 | denotes | FRDA |
| 22798143-6#9#12#gene2548 | 1026-1029 | gene2548 | denotes | GAA |
| 22798143-6#48#52#diseaseC1856689 | 1065-1069 | diseaseC1856689 | denotes | FRDA |
| 22798143-9#125#129#gene4436 | 1562-1566 | gene4436 | denotes | MSH2 |
| 22798143-9#135#138#gene2395 | 1572-1575 | gene2395 | denotes | FXN |
| 22798143-9#151#155#diseaseC1856689 | 1588-1592 | diseaseC1856689 | denotes | FRDA |
| 35#38#gene254871#88#diseaseC0016719 | 22798143-0#35#38#gene2548 | 22798143-0#71#88#diseaseC0016719 | associated_with | GAA,Friedreich ataxia |
| 139#142#gene239524#41#diseaseC0016719 | 22798143-1#139#142#gene2395 | 22798143-1#24#41#diseaseC0016719 | associated_with | FXN,Friedreich ataxia |
| 147#151#gene546067#71#diseaseC1856689 | 22798143-3#147#151#gene5460 | 22798143-3#67#71#diseaseC1856689 | associated_with | Oct4,FRDA |
| 9#12#gene254848#52#diseaseC1856689 | 22798143-6#9#12#gene2548 | 22798143-6#48#52#diseaseC1856689 | associated_with | GAA,FRDA |
| 125#129#gene4436151#155#diseaseC1856689 | 22798143-9#125#129#gene4436 | 22798143-9#151#155#diseaseC1856689 | associated_with | MSH2,FRDA |
| 135#138#gene2395151#155#diseaseC1856689 | 22798143-9#135#138#gene2395 | 22798143-9#151#155#diseaseC1856689 | associated_with | FXN,FRDA |
GlyCosmos600-MAT
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| PD-MAT-B_T1 | 109-113 | http://purl.obolibrary.org/obo/MAT_0000239 | denotes | stem |
| PD-MAT-B_T2 | 617-621 | http://purl.obolibrary.org/obo/MAT_0000239 | denotes | stem |
| PD-MAT-B_T3 | 1095-1099 | http://purl.obolibrary.org/obo/MAT_0000239 | denotes | stem |
| PD-MAT-B_T4 | 1261-1265 | http://purl.obolibrary.org/obo/MAT_0000239 | denotes | stem |
| PD-MAT-B_T5 | 1311-1315 | http://purl.obolibrary.org/obo/MAT_0000239 | denotes | stem |
| PD-MAT-B_T6 | 109-119 | http://purl.obolibrary.org/obo/MAT_0000185 | denotes | stem cells |
| PD-MAT-B_T7 | 617-627 | http://purl.obolibrary.org/obo/MAT_0000185 | denotes | stem cells |
| PD-MAT-B_T8 | 1095-1105 | http://purl.obolibrary.org/obo/MAT_0000185 | denotes | stem cells |
| PD-MAT-B_T9 | 1261-1271 | http://purl.obolibrary.org/obo/MAT_0000185 | denotes | stem cells |
| PD-MAT-B_T10 | 1311-1321 | http://purl.obolibrary.org/obo/MAT_0000185 | denotes | stem cells |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| TextSentencer_T1 | 0-120 | Sentence | denotes | Role of mismatch repair enzymes in GAA·TTC triplet-repeat expansion in Friedreich ataxia induced pluripotent stem cells. |
| TextSentencer_T2 | 121-269 | Sentence | denotes | The genetic mutation in Friedreich ataxia (FRDA) is a hyperexpansion of the triplet-repeat sequence GAA·TTC within the first intron of the FXN gene. |
| TextSentencer_T3 | 270-588 | Sentence | denotes | Although yeast and reporter construct models for GAA·TTC triplet-repeat expansion have been reported, studies on FRDA pathogenesis and therapeutic development are limited by the availability of an appropriate cell model in which to study the mechanism of instability of the GAA·TTC triplet repeats in the human genome. |
| TextSentencer_T4 | 589-764 | Sentence | denotes | Herein, induced pluripotent stem cells (iPSCs) were generated from FRDA patient fibroblasts after transduction with the four transcription factors Oct4, Sox2, Klf4, and c-Myc. |
| TextSentencer_T5 | 765-890 | Sentence | denotes | These cells were differentiated into neurospheres and neuronal precursors in vitro, providing a valuable cell model for FRDA. |
| TextSentencer_T6 | 891-1016 | Sentence | denotes | During propagation of the iPSCs, GAA·TTC triplet repeats expanded at a rate of about two GAA·TTC triplet repeats/replication. |
| TextSentencer_T7 | 1017-1106 | Sentence | denotes | However, GAA·TTC triplet repeats were stable in FRDA fibroblasts and neuronal stem cells. |
| TextSentencer_T8 | 1107-1348 | Sentence | denotes | The mismatch repair enzymes MSH2, MSH3, and MSH6, implicated in repeat instability in other triplet-repeat diseases, were highly expressed in pluripotent stem cells compared with fibroblasts and neuronal stem cells and occupied FXN intron 1. |
| TextSentencer_T9 | 1349-1436 | Sentence | denotes | In addition, shRNA silencing of MSH2 and MSH6 impeded GAA·TTC triplet-repeat expansion. |
| TextSentencer_T10 | 1437-1599 | Sentence | denotes | A specific pyrrole-imidazole polyamide targeting GAA·TTC triplet-repeat DNA partially blocked repeat expansion by displacing MSH2 from FXN intron 1 in FRDA iPSCs. |
| TextSentencer_T11 | 1600-1751 | Sentence | denotes | These studies suggest that in FRDA, GAA·TTC triplet-repeat instability occurs in embryonic cells and involves the highly active mismatch repair system. |
| T1 | 0-120 | Sentence | denotes | Role of mismatch repair enzymes in GAA·TTC triplet-repeat expansion in Friedreich ataxia induced pluripotent stem cells. |
| T2 | 121-269 | Sentence | denotes | The genetic mutation in Friedreich ataxia (FRDA) is a hyperexpansion of the triplet-repeat sequence GAA·TTC within the first intron of the FXN gene. |
| T3 | 270-588 | Sentence | denotes | Although yeast and reporter construct models for GAA·TTC triplet-repeat expansion have been reported, studies on FRDA pathogenesis and therapeutic development are limited by the availability of an appropriate cell model in which to study the mechanism of instability of the GAA·TTC triplet repeats in the human genome. |
| T4 | 589-764 | Sentence | denotes | Herein, induced pluripotent stem cells (iPSCs) were generated from FRDA patient fibroblasts after transduction with the four transcription factors Oct4, Sox2, Klf4, and c-Myc. |
| T5 | 765-890 | Sentence | denotes | These cells were differentiated into neurospheres and neuronal precursors in vitro, providing a valuable cell model for FRDA. |
| T6 | 891-1016 | Sentence | denotes | During propagation of the iPSCs, GAA·TTC triplet repeats expanded at a rate of about two GAA·TTC triplet repeats/replication. |
| T7 | 1017-1106 | Sentence | denotes | However, GAA·TTC triplet repeats were stable in FRDA fibroblasts and neuronal stem cells. |
| T8 | 1107-1348 | Sentence | denotes | The mismatch repair enzymes MSH2, MSH3, and MSH6, implicated in repeat instability in other triplet-repeat diseases, were highly expressed in pluripotent stem cells compared with fibroblasts and neuronal stem cells and occupied FXN intron 1. |
| T9 | 1349-1436 | Sentence | denotes | In addition, shRNA silencing of MSH2 and MSH6 impeded GAA·TTC triplet-repeat expansion. |
| T10 | 1437-1599 | Sentence | denotes | A specific pyrrole-imidazole polyamide targeting GAA·TTC triplet-repeat DNA partially blocked repeat expansion by displacing MSH2 from FXN intron 1 in FRDA iPSCs. |
| T11 | 1600-1751 | Sentence | denotes | These studies suggest that in FRDA, GAA·TTC triplet-repeat instability occurs in embryonic cells and involves the highly active mismatch repair system. |
pubmed-enju-pas
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| EnjuParser_T0 | 0-4 | NN | denotes | Role |
| EnjuParser_T1 | 5-7 | IN | denotes | of |
| EnjuParser_T2 | 8-16 | NN | denotes | mismatch |
| EnjuParser_T3 | 17-23 | NN | denotes | repair |
| EnjuParser_T4 | 24-31 | NNS | denotes | enzymes |
| EnjuParser_T5 | 32-34 | IN | denotes | in |
| EnjuParser_T6 | 35-42 | NN | denotes | GAA·TTC |
| EnjuParser_T7 | 43-57 | JJ | denotes | triplet-repeat |
| EnjuParser_T8 | 58-67 | NN | denotes | expansion |
| EnjuParser_T9 | 68-70 | IN | denotes | in |
| EnjuParser_T10 | 71-81 | NNP | denotes | Friedreich |
| EnjuParser_T11 | 82-88 | NN | denotes | ataxia |
| EnjuParser_T12 | 89-96 | VBD | denotes | induced |
| EnjuParser_T13 | 97-108 | JJ | denotes | pluripotent |
| EnjuParser_T14 | 109-113 | NN | denotes | stem |
| EnjuParser_T15 | 114-119 | NNS | denotes | cells |
| EnjuParser_T16 | 121-124 | DT | denotes | The |
| EnjuParser_T17 | 125-132 | JJ | denotes | genetic |
| EnjuParser_T18 | 133-141 | NN | denotes | mutation |
| EnjuParser_T19 | 142-144 | IN | denotes | in |
| EnjuParser_T20 | 145-155 | NNP | denotes | Friedreich |
| EnjuParser_T21 | 156-162 | NN | denotes | ataxia |
| EnjuParser_T22 | 163-164 | -LRB- | denotes | ( |
| EnjuParser_T23 | 164-168 | NN | denotes | FRDA |
| EnjuParser_T24 | 168-169 | -RRB- | denotes | ) |
| EnjuParser_T25 | 170-172 | VBZ | denotes | is |
| EnjuParser_T26 | 173-174 | DT | denotes | a |
| EnjuParser_T27 | 175-189 | NN | denotes | hyperexpansion |
| EnjuParser_T28 | 190-192 | IN | denotes | of |
| EnjuParser_T29 | 193-196 | DT | denotes | the |
| EnjuParser_T30 | 197-211 | JJ | denotes | triplet-repeat |
| EnjuParser_T31 | 212-220 | NN | denotes | sequence |
| EnjuParser_T32 | 221-228 | NN | denotes | GAA·TTC |
| EnjuParser_T33 | 229-235 | IN | denotes | within |
| EnjuParser_T34 | 236-239 | DT | denotes | the |
| EnjuParser_T35 | 240-245 | JJ | denotes | first |
| EnjuParser_T36 | 246-252 | NN | denotes | intron |
| EnjuParser_T37 | 253-255 | IN | denotes | of |
| EnjuParser_T38 | 256-259 | DT | denotes | the |
| EnjuParser_T39 | 260-263 | NN | denotes | FXN |
| EnjuParser_T40 | 264-268 | NN | denotes | gene |
| EnjuParser_T41 | 270-278 | IN | denotes | Although |
| EnjuParser_T42 | 279-284 | NN | denotes | yeast |
| EnjuParser_T43 | 285-288 | CC | denotes | and |
| EnjuParser_T44 | 289-297 | NN | denotes | reporter |
| EnjuParser_T45 | 298-307 | NN | denotes | construct |
| EnjuParser_T46 | 308-314 | NNS | denotes | models |
| EnjuParser_T47 | 315-318 | IN | denotes | for |
| EnjuParser_T48 | 319-326 | NN | denotes | GAA·TTC |
| EnjuParser_T49 | 327-341 | JJ | denotes | triplet-repeat |
| EnjuParser_T50 | 342-351 | NN | denotes | expansion |
| EnjuParser_T51 | 352-356 | VBP | denotes | have |
| EnjuParser_T52 | 357-361 | VBN | denotes | been |
| EnjuParser_T53 | 362-370 | VBN | denotes | reported |
| EnjuParser_T54 | 370-371 | -COMMA- | denotes | , |
| EnjuParser_T55 | 372-379 | NNS | denotes | studies |
| EnjuParser_T56 | 380-382 | IN | denotes | on |
| EnjuParser_T57 | 383-387 | NN | denotes | FRDA |
| EnjuParser_T58 | 388-400 | NN | denotes | pathogenesis |
| EnjuParser_T59 | 401-404 | CC | denotes | and |
| EnjuParser_T60 | 405-416 | JJ | denotes | therapeutic |
| EnjuParser_T61 | 417-428 | NN | denotes | development |
| EnjuParser_T62 | 429-432 | VBP | denotes | are |
| EnjuParser_T63 | 433-440 | VBN | denotes | limited |
| EnjuParser_T64 | 441-443 | IN | denotes | by |
| EnjuParser_T65 | 444-447 | DT | denotes | the |
| EnjuParser_T66 | 448-460 | NN | denotes | availability |
| EnjuParser_T67 | 461-463 | IN | denotes | of |
| EnjuParser_T68 | 464-466 | DT | denotes | an |
| EnjuParser_T69 | 467-478 | JJ | denotes | appropriate |
| EnjuParser_T70 | 479-483 | NN | denotes | cell |
| EnjuParser_T71 | 484-489 | NN | denotes | model |
| EnjuParser_T72 | 490-492 | IN | denotes | in |
| EnjuParser_T73 | 493-498 | WDT | denotes | which |
| EnjuParser_T74 | 499-501 | TO | denotes | to |
| EnjuParser_T75 | 502-507 | VB | denotes | study |
| EnjuParser_T76 | 508-511 | DT | denotes | the |
| EnjuParser_T77 | 512-521 | NN | denotes | mechanism |
| EnjuParser_T78 | 522-524 | IN | denotes | of |
| EnjuParser_T79 | 525-536 | NN | denotes | instability |
| EnjuParser_T80 | 537-539 | IN | denotes | of |
| EnjuParser_T81 | 540-543 | DT | denotes | the |
| EnjuParser_T82 | 544-551 | NN | denotes | GAA·TTC |
| EnjuParser_T83 | 552-559 | NN | denotes | triplet |
| EnjuParser_T84 | 560-567 | NNS | denotes | repeats |
| EnjuParser_T85 | 568-570 | IN | denotes | in |
| EnjuParser_T86 | 571-574 | DT | denotes | the |
| EnjuParser_T87 | 575-580 | JJ | denotes | human |
| EnjuParser_T88 | 581-587 | NN | denotes | genome |
| EnjuParser_T89 | 589-595 | RB | denotes | Herein |
| EnjuParser_T90 | 595-596 | -COMMA- | denotes | , |
| EnjuParser_T91 | 597-604 | VBD | denotes | induced |
| EnjuParser_T92 | 605-616 | JJ | denotes | pluripotent |
| EnjuParser_T93 | 617-621 | NN | denotes | stem |
| EnjuParser_T94 | 622-627 | NNS | denotes | cells |
| EnjuParser_T95 | 628-629 | -LRB- | denotes | ( |
| EnjuParser_T96 | 629-634 | NNS | denotes | iPSCs |
| EnjuParser_T97 | 634-635 | -RRB- | denotes | ) |
| EnjuParser_T98 | 636-640 | VBD | denotes | were |
| EnjuParser_T99 | 641-650 | VBN | denotes | generated |
| EnjuParser_T100 | 651-655 | IN | denotes | from |
| EnjuParser_T101 | 656-660 | NN | denotes | FRDA |
| EnjuParser_T102 | 661-668 | NN | denotes | patient |
| EnjuParser_T103 | 669-680 | NNS | denotes | fibroblasts |
| EnjuParser_T104 | 681-686 | IN | denotes | after |
| EnjuParser_T105 | 687-699 | NN | denotes | transduction |
| EnjuParser_T106 | 700-704 | IN | denotes | with |
| EnjuParser_T107 | 705-708 | DT | denotes | the |
| EnjuParser_T108 | 709-713 | CD | denotes | four |
| EnjuParser_T109 | 714-727 | NN | denotes | transcription |
| EnjuParser_T110 | 728-735 | NNS | denotes | factors |
| EnjuParser_T111 | 736-740 | NN | denotes | Oct4 |
| EnjuParser_T112 | 740-741 | -COMMA- | denotes | , |
| EnjuParser_T113 | 742-746 | NN | denotes | Sox2 |
| EnjuParser_T114 | 746-747 | -COMMA- | denotes | , |
| EnjuParser_T115 | 748-752 | NN | denotes | Klf4 |
| EnjuParser_T116 | 752-753 | -COMMA- | denotes | , |
| EnjuParser_T117 | 754-757 | CC | denotes | and |
| EnjuParser_T118 | 758-764 | NN | denotes | c-Myc. |
| EnjuParser_T119 | 765-770 | DT | denotes | These |
| EnjuParser_T120 | 771-776 | NNS | denotes | cells |
| EnjuParser_T121 | 777-781 | VBD | denotes | were |
| EnjuParser_T122 | 782-796 | VBN | denotes | differentiated |
| EnjuParser_T123 | 797-801 | IN | denotes | into |
| EnjuParser_T124 | 802-814 | NNS | denotes | neurospheres |
| EnjuParser_T125 | 815-818 | CC | denotes | and |
| EnjuParser_T126 | 819-827 | JJ | denotes | neuronal |
| EnjuParser_T127 | 828-838 | NNS | denotes | precursors |
| EnjuParser_T128 | 839-841 | FW | denotes | in |
| EnjuParser_T129 | 842-847 | FW | denotes | vitro |
| EnjuParser_T130 | 847-848 | -COMMA- | denotes | , |
| EnjuParser_T131 | 849-858 | VBG | denotes | providing |
| EnjuParser_T132 | 859-860 | DT | denotes | a |
| EnjuParser_T133 | 861-869 | JJ | denotes | valuable |
| EnjuParser_T134 | 870-874 | NN | denotes | cell |
| EnjuParser_T135 | 875-880 | NN | denotes | model |
| EnjuParser_T136 | 881-884 | IN | denotes | for |
| EnjuParser_T137 | 885-889 | NN | denotes | FRDA |
| EnjuParser_T138 | 891-897 | IN | denotes | During |
| EnjuParser_T139 | 898-909 | NN | denotes | propagation |
| EnjuParser_T140 | 910-912 | IN | denotes | of |
| EnjuParser_T141 | 913-916 | DT | denotes | the |
| EnjuParser_T142 | 917-922 | NNS | denotes | iPSCs |
| EnjuParser_T143 | 922-923 | -COMMA- | denotes | , |
| EnjuParser_T144 | 924-931 | NN | denotes | GAA·TTC |
| EnjuParser_T145 | 932-939 | NN | denotes | triplet |
| EnjuParser_T146 | 940-947 | NNS | denotes | repeats |
| EnjuParser_T147 | 948-956 | VBN | denotes | expanded |
| EnjuParser_T148 | 957-959 | IN | denotes | at |
| EnjuParser_T149 | 960-961 | DT | denotes | a |
| EnjuParser_T150 | 962-966 | NN | denotes | rate |
| EnjuParser_T151 | 967-969 | IN | denotes | of |
| EnjuParser_T152 | 970-975 | IN | denotes | about |
| EnjuParser_T153 | 976-979 | CD | denotes | two |
| EnjuParser_T154 | 980-987 | NN | denotes | GAA·TTC |
| EnjuParser_T155 | 988-995 | NN | denotes | triplet |
| EnjuParser_T156 | 996-1015 | NN | denotes | repeats/replication |
| EnjuParser_T157 | 1017-1024 | RB | denotes | However |
| EnjuParser_T158 | 1024-1025 | -COMMA- | denotes | , |
| EnjuParser_T159 | 1026-1033 | NN | denotes | GAA·TTC |
| EnjuParser_T160 | 1034-1041 | NN | denotes | triplet |
| EnjuParser_T161 | 1042-1049 | NNS | denotes | repeats |
| EnjuParser_T162 | 1050-1054 | VBD | denotes | were |
| EnjuParser_T163 | 1055-1061 | JJ | denotes | stable |
| EnjuParser_T164 | 1062-1064 | IN | denotes | in |
| EnjuParser_T165 | 1065-1069 | NN | denotes | FRDA |
| EnjuParser_T166 | 1070-1081 | NNS | denotes | fibroblasts |
| EnjuParser_T167 | 1082-1085 | CC | denotes | and |
| EnjuParser_T168 | 1086-1094 | JJ | denotes | neuronal |
| EnjuParser_T169 | 1095-1099 | NN | denotes | stem |
| EnjuParser_T170 | 1100-1105 | NNS | denotes | cells |
| EnjuParser_T171 | 1107-1110 | DT | denotes | The |
| EnjuParser_T172 | 1111-1119 | NN | denotes | mismatch |
| EnjuParser_T173 | 1120-1126 | NN | denotes | repair |
| EnjuParser_T174 | 1127-1134 | NNS | denotes | enzymes |
| EnjuParser_T175 | 1135-1139 | NN | denotes | MSH2 |
| EnjuParser_T176 | 1139-1140 | -COMMA- | denotes | , |
| EnjuParser_T177 | 1141-1145 | NN | denotes | MSH3 |
| EnjuParser_T178 | 1145-1146 | -COMMA- | denotes | , |
| EnjuParser_T179 | 1147-1150 | CC | denotes | and |
| EnjuParser_T180 | 1151-1155 | NN | denotes | MSH6 |
| EnjuParser_T181 | 1155-1156 | -COMMA- | denotes | , |
| EnjuParser_T182 | 1157-1167 | VBN | denotes | implicated |
| EnjuParser_T183 | 1168-1170 | IN | denotes | in |
| EnjuParser_T184 | 1171-1177 | NN | denotes | repeat |
| EnjuParser_T185 | 1178-1189 | NN | denotes | instability |
| EnjuParser_T186 | 1190-1192 | IN | denotes | in |
| EnjuParser_T187 | 1193-1198 | JJ | denotes | other |
| EnjuParser_T188 | 1199-1213 | JJ | denotes | triplet-repeat |
| EnjuParser_T189 | 1214-1222 | NNS | denotes | diseases |
| EnjuParser_T190 | 1222-1223 | -COMMA- | denotes | , |
| EnjuParser_T191 | 1224-1228 | VBD | denotes | were |
| EnjuParser_T192 | 1229-1235 | RB | denotes | highly |
| EnjuParser_T193 | 1236-1245 | VBN | denotes | expressed |
| EnjuParser_T194 | 1246-1248 | IN | denotes | in |
| EnjuParser_T195 | 1249-1260 | JJ | denotes | pluripotent |
| EnjuParser_T196 | 1261-1265 | NN | denotes | stem |
| EnjuParser_T197 | 1266-1271 | NNS | denotes | cells |
| EnjuParser_T198 | 1272-1280 | VBN | denotes | compared |
| EnjuParser_T199 | 1281-1285 | IN | denotes | with |
| EnjuParser_T200 | 1286-1297 | NNS | denotes | fibroblasts |
| EnjuParser_T201 | 1298-1301 | CC | denotes | and |
| EnjuParser_T202 | 1302-1310 | JJ | denotes | neuronal |
| EnjuParser_T203 | 1311-1315 | NN | denotes | stem |
| EnjuParser_T204 | 1316-1321 | NNS | denotes | cells |
| EnjuParser_T205 | 1322-1325 | CC | denotes | and |
| EnjuParser_T206 | 1326-1334 | VBD | denotes | occupied |
| EnjuParser_T207 | 1335-1338 | NN | denotes | FXN |
| EnjuParser_T208 | 1339-1345 | NN | denotes | intron |
| EnjuParser_T209 | 1346-1347 | CD | denotes | 1 |
| EnjuParser_T210 | 1349-1351 | IN | denotes | In |
| EnjuParser_T211 | 1352-1360 | NN | denotes | addition |
| EnjuParser_T212 | 1360-1361 | -COMMA- | denotes | , |
| EnjuParser_T213 | 1362-1367 | NN | denotes | shRNA |
| EnjuParser_T214 | 1368-1377 | NN | denotes | silencing |
| EnjuParser_T215 | 1378-1380 | IN | denotes | of |
| EnjuParser_T216 | 1381-1385 | NN | denotes | MSH2 |
| EnjuParser_T217 | 1386-1389 | CC | denotes | and |
| EnjuParser_T218 | 1390-1394 | NN | denotes | MSH6 |
| EnjuParser_T219 | 1395-1402 | VBD | denotes | impeded |
| EnjuParser_T220 | 1403-1410 | NN | denotes | GAA·TTC |
| EnjuParser_T221 | 1411-1425 | JJ | denotes | triplet-repeat |
| EnjuParser_T222 | 1426-1435 | NN | denotes | expansion |
| EnjuParser_T223 | 1437-1438 | DT | denotes | A |
| EnjuParser_T224 | 1439-1447 | JJ | denotes | specific |
| EnjuParser_T225 | 1448-1465 | NN | denotes | pyrrole-imidazole |
| EnjuParser_T226 | 1466-1475 | NN | denotes | polyamide |
| EnjuParser_T227 | 1476-1485 | VBG | denotes | targeting |
| EnjuParser_T228 | 1486-1493 | NN | denotes | GAA·TTC |
| EnjuParser_T229 | 1494-1508 | JJ | denotes | triplet-repeat |
| EnjuParser_T230 | 1509-1512 | NN | denotes | DNA |
| EnjuParser_T231 | 1513-1522 | RB | denotes | partially |
| EnjuParser_T232 | 1523-1530 | VBD | denotes | blocked |
| EnjuParser_T233 | 1531-1537 | NN | denotes | repeat |
| EnjuParser_T234 | 1538-1547 | NN | denotes | expansion |
| EnjuParser_T235 | 1548-1550 | IN | denotes | by |
| EnjuParser_T236 | 1551-1561 | VBG | denotes | displacing |
| EnjuParser_T237 | 1562-1566 | NN | denotes | MSH2 |
| EnjuParser_T238 | 1567-1571 | IN | denotes | from |
| EnjuParser_T239 | 1572-1575 | NN | denotes | FXN |
| EnjuParser_T240 | 1576-1582 | NN | denotes | intron |
| EnjuParser_T241 | 1583-1584 | CD | denotes | 1 |
| EnjuParser_T242 | 1585-1587 | IN | denotes | in |
| EnjuParser_T243 | 1588-1592 | NN | denotes | FRDA |
| EnjuParser_T244 | 1593-1598 | NNS | denotes | iPSCs |
| EnjuParser_T245 | 1600-1605 | DT | denotes | These |
| EnjuParser_T246 | 1606-1613 | NNS | denotes | studies |
| EnjuParser_T247 | 1614-1621 | VBP | denotes | suggest |
| EnjuParser_T248 | 1622-1626 | IN | denotes | that |
| EnjuParser_T249 | 1627-1629 | IN | denotes | in |
| EnjuParser_T250 | 1630-1634 | NNP | denotes | FRDA |
| EnjuParser_T251 | 1634-1635 | -COMMA- | denotes | , |
| EnjuParser_T252 | 1636-1643 | NN | denotes | GAA·TTC |
| EnjuParser_T253 | 1644-1658 | JJ | denotes | triplet-repeat |
| EnjuParser_T254 | 1659-1670 | NN | denotes | instability |
| EnjuParser_T255 | 1671-1677 | VBZ | denotes | occurs |
| EnjuParser_T256 | 1678-1680 | IN | denotes | in |
| EnjuParser_T257 | 1681-1690 | JJ | denotes | embryonic |
| EnjuParser_T258 | 1691-1696 | NNS | denotes | cells |
| EnjuParser_T259 | 1697-1700 | CC | denotes | and |
| EnjuParser_T260 | 1701-1709 | VBZ | denotes | involves |
| EnjuParser_T261 | 1710-1713 | DT | denotes | the |
| EnjuParser_T262 | 1714-1720 | RB | denotes | highly |
| EnjuParser_T263 | 1721-1727 | JJ | denotes | active |
| EnjuParser_T264 | 1728-1736 | NN | denotes | mismatch |
| EnjuParser_T265 | 1737-1743 | NN | denotes | repair |
| EnjuParser_T266 | 1744-1750 | NN | denotes | system |
| EnjuParser_R193 | EnjuParser_T193 | EnjuParser_T192 | arg1Of | expressed,highly |
| EnjuParser_R194 | EnjuParser_T179 | EnjuParser_T193 | arg2Of | and,expressed |
| EnjuParser_R195 | EnjuParser_T193 | EnjuParser_T194 | arg1Of | expressed,in |
| EnjuParser_R196 | EnjuParser_T197 | EnjuParser_T194 | arg2Of | cells,in |
| EnjuParser_R197 | EnjuParser_T197 | EnjuParser_T195 | arg1Of | cells,pluripotent |
| EnjuParser_R198 | EnjuParser_T197 | EnjuParser_T196 | arg1Of | cells,stem |
| EnjuParser_R199 | EnjuParser_T193 | EnjuParser_T198 | arg1Of | expressed,compared |
| EnjuParser_R200 | EnjuParser_T199 | EnjuParser_T198 | arg2Of | with,compared |
| EnjuParser_R201 | EnjuParser_T201 | EnjuParser_T199 | arg2Of | and,with |
| EnjuParser_R202 | EnjuParser_T200 | EnjuParser_T201 | arg1Of | fibroblasts,and |
| EnjuParser_R203 | EnjuParser_T204 | EnjuParser_T201 | arg2Of | cells,and |
| EnjuParser_R204 | EnjuParser_T204 | EnjuParser_T202 | arg1Of | cells,neuronal |
| EnjuParser_R205 | EnjuParser_T204 | EnjuParser_T203 | arg1Of | cells,stem |
| EnjuParser_R206 | EnjuParser_T193 | EnjuParser_T205 | arg1Of | expressed,and |
| EnjuParser_R207 | EnjuParser_T206 | EnjuParser_T205 | arg2Of | occupied,and |
| EnjuParser_R208 | EnjuParser_T179 | EnjuParser_T206 | arg1Of | and,occupied |
| EnjuParser_R209 | EnjuParser_T208 | EnjuParser_T206 | arg2Of | intron,occupied |
| EnjuParser_R210 | EnjuParser_T208 | EnjuParser_T207 | arg1Of | intron,FXN |
| EnjuParser_R211 | EnjuParser_T208 | EnjuParser_T209 | arg1Of | intron,1 |
| EnjuParser_R212 | EnjuParser_T219 | EnjuParser_T210 | arg1Of | impeded,In |
| EnjuParser_R213 | EnjuParser_T211 | EnjuParser_T210 | arg2Of | addition,In |
| EnjuParser_R245 | EnjuParser_T244 | EnjuParser_T243 | arg1Of | iPSCs,FRDA |
| EnjuParser_R246 | EnjuParser_T246 | EnjuParser_T245 | arg1Of | studies,These |
| EnjuParser_R247 | EnjuParser_T246 | EnjuParser_T247 | arg1Of | studies,suggest |
| EnjuParser_R248 | EnjuParser_T259 | EnjuParser_T247 | arg2Of | and,suggest |
| EnjuParser_R249 | EnjuParser_T259 | EnjuParser_T248 | arg1Of | and,that |
| EnjuParser_R250 | EnjuParser_T259 | EnjuParser_T249 | arg1Of | and,in |
| EnjuParser_R251 | EnjuParser_T250 | EnjuParser_T249 | arg2Of | FRDA,in |
| EnjuParser_R252 | EnjuParser_T259 | EnjuParser_T251 | arg1Of | and,"," |
| EnjuParser_R253 | EnjuParser_T254 | EnjuParser_T252 | arg1Of | instability,GAA·TTC |
| EnjuParser_R254 | EnjuParser_T254 | EnjuParser_T253 | arg1Of | instability,triplet-repeat |
| EnjuParser_R255 | EnjuParser_T254 | EnjuParser_T255 | arg1Of | instability,occurs |
| EnjuParser_R256 | EnjuParser_T255 | EnjuParser_T256 | arg1Of | occurs,in |
| EnjuParser_R257 | EnjuParser_T258 | EnjuParser_T256 | arg2Of | cells,in |
| EnjuParser_R258 | EnjuParser_T258 | EnjuParser_T257 | arg1Of | cells,embryonic |
| EnjuParser_R259 | EnjuParser_T255 | EnjuParser_T259 | arg1Of | occurs,and |
| EnjuParser_R260 | EnjuParser_T260 | EnjuParser_T259 | arg2Of | involves,and |
| EnjuParser_R261 | EnjuParser_T254 | EnjuParser_T260 | arg1Of | instability,involves |
| EnjuParser_R262 | EnjuParser_T266 | EnjuParser_T260 | arg2Of | system,involves |
| EnjuParser_R263 | EnjuParser_T266 | EnjuParser_T261 | arg1Of | system,the |
| EnjuParser_R264 | EnjuParser_T263 | EnjuParser_T262 | arg1Of | active,highly |
| EnjuParser_R265 | EnjuParser_T266 | EnjuParser_T263 | arg1Of | system,active |
| EnjuParser_R266 | EnjuParser_T266 | EnjuParser_T264 | arg1Of | system,mismatch |
| EnjuParser_R267 | EnjuParser_T266 | EnjuParser_T265 | arg1Of | system,repair |
| EnjuParser_R0 | EnjuParser_T0 | EnjuParser_T1 | arg1Of | Role,of |
| EnjuParser_R1 | EnjuParser_T4 | EnjuParser_T1 | arg2Of | enzymes,of |
| EnjuParser_R2 | EnjuParser_T4 | EnjuParser_T2 | arg1Of | enzymes,mismatch |
| EnjuParser_R3 | EnjuParser_T4 | EnjuParser_T3 | arg1Of | enzymes,repair |
| EnjuParser_R4 | EnjuParser_T0 | EnjuParser_T5 | arg1Of | Role,in |
| EnjuParser_R5 | EnjuParser_T8 | EnjuParser_T5 | arg2Of | expansion,in |
| EnjuParser_R6 | EnjuParser_T8 | EnjuParser_T6 | arg1Of | expansion,GAA·TTC |
| EnjuParser_R7 | EnjuParser_T8 | EnjuParser_T7 | arg1Of | expansion,triplet-repeat |
| EnjuParser_R8 | EnjuParser_T8 | EnjuParser_T9 | arg1Of | expansion,in |
| EnjuParser_R9 | EnjuParser_T11 | EnjuParser_T9 | arg2Of | ataxia,in |
| EnjuParser_R10 | EnjuParser_T11 | EnjuParser_T10 | arg1Of | ataxia,Friedreich |
| EnjuParser_R11 | EnjuParser_T0 | EnjuParser_T12 | arg1Of | Role,induced |
| EnjuParser_R12 | EnjuParser_T15 | EnjuParser_T12 | arg2Of | cells,induced |
| EnjuParser_R13 | EnjuParser_T15 | EnjuParser_T13 | arg1Of | cells,pluripotent |
| EnjuParser_R14 | EnjuParser_T15 | EnjuParser_T14 | arg1Of | cells,stem |
| EnjuParser_R15 | EnjuParser_T18 | EnjuParser_T16 | arg1Of | mutation,The |
| EnjuParser_R16 | EnjuParser_T18 | EnjuParser_T17 | arg1Of | mutation,genetic |
| EnjuParser_R17 | EnjuParser_T18 | EnjuParser_T19 | arg1Of | mutation,in |
| EnjuParser_R18 | EnjuParser_T21 | EnjuParser_T19 | arg2Of | ataxia,in |
| EnjuParser_R19 | EnjuParser_T21 | EnjuParser_T20 | arg1Of | ataxia,Friedreich |
| EnjuParser_R20 | EnjuParser_T21 | EnjuParser_T22 | arg1Of | ataxia,( |
| EnjuParser_R21 | EnjuParser_T23 | EnjuParser_T22 | arg2Of | FRDA,( |
| EnjuParser_R22 | EnjuParser_T24 | EnjuParser_T22 | arg3Of | ),( |
| EnjuParser_R23 | EnjuParser_T18 | EnjuParser_T25 | arg1Of | mutation,is |
| EnjuParser_R24 | EnjuParser_T27 | EnjuParser_T25 | arg2Of | hyperexpansion,is |
| EnjuParser_R25 | EnjuParser_T27 | EnjuParser_T26 | arg1Of | hyperexpansion,a |
| EnjuParser_R26 | EnjuParser_T27 | EnjuParser_T28 | arg1Of | hyperexpansion,of |
| EnjuParser_R27 | EnjuParser_T32 | EnjuParser_T28 | arg2Of | GAA·TTC,of |
| EnjuParser_R28 | EnjuParser_T32 | EnjuParser_T29 | arg1Of | GAA·TTC,the |
| EnjuParser_R29 | EnjuParser_T32 | EnjuParser_T30 | arg1Of | GAA·TTC,triplet-repeat |
| EnjuParser_R30 | EnjuParser_T32 | EnjuParser_T31 | arg1Of | GAA·TTC,sequence |
| EnjuParser_R31 | EnjuParser_T27 | EnjuParser_T33 | arg1Of | hyperexpansion,within |
| EnjuParser_R32 | EnjuParser_T36 | EnjuParser_T33 | arg2Of | intron,within |
| EnjuParser_R33 | EnjuParser_T36 | EnjuParser_T34 | arg1Of | intron,the |
| EnjuParser_R34 | EnjuParser_T36 | EnjuParser_T35 | arg1Of | intron,first |
| EnjuParser_R35 | EnjuParser_T36 | EnjuParser_T37 | arg1Of | intron,of |
| EnjuParser_R36 | EnjuParser_T40 | EnjuParser_T37 | arg2Of | gene,of |
| EnjuParser_R37 | EnjuParser_T40 | EnjuParser_T38 | arg1Of | gene,the |
| EnjuParser_R38 | EnjuParser_T40 | EnjuParser_T39 | arg1Of | gene,FXN |
| EnjuParser_R39 | EnjuParser_T63 | EnjuParser_T41 | arg1Of | limited,Although |
| EnjuParser_R40 | EnjuParser_T53 | EnjuParser_T41 | arg2Of | reported,Although |
| EnjuParser_R41 | EnjuParser_T46 | EnjuParser_T42 | arg1Of | models,yeast |
| EnjuParser_R42 | EnjuParser_T42 | EnjuParser_T43 | arg1Of | yeast,and |
| EnjuParser_R43 | EnjuParser_T44 | EnjuParser_T43 | arg2Of | reporter,and |
| EnjuParser_R44 | EnjuParser_T46 | EnjuParser_T44 | arg1Of | models,reporter |
| EnjuParser_R45 | EnjuParser_T46 | EnjuParser_T45 | arg1Of | models,construct |
| EnjuParser_R46 | EnjuParser_T46 | EnjuParser_T47 | arg1Of | models,for |
| EnjuParser_R47 | EnjuParser_T50 | EnjuParser_T47 | arg2Of | expansion,for |
| EnjuParser_R48 | EnjuParser_T50 | EnjuParser_T48 | arg1Of | expansion,GAA·TTC |
| EnjuParser_R49 | EnjuParser_T50 | EnjuParser_T49 | arg1Of | expansion,triplet-repeat |
| EnjuParser_R50 | EnjuParser_T46 | EnjuParser_T51 | arg1Of | models,have |
| EnjuParser_R51 | EnjuParser_T53 | EnjuParser_T51 | arg2Of | reported,have |
| EnjuParser_R52 | EnjuParser_T46 | EnjuParser_T52 | arg1Of | models,been |
| EnjuParser_R53 | EnjuParser_T53 | EnjuParser_T52 | arg2Of | reported,been |
| EnjuParser_R54 | EnjuParser_T46 | EnjuParser_T53 | arg2Of | models,reported |
| EnjuParser_R55 | EnjuParser_T63 | EnjuParser_T54 | arg1Of | limited,"," |
| EnjuParser_R56 | EnjuParser_T55 | EnjuParser_T56 | arg1Of | studies,on |
| EnjuParser_R57 | EnjuParser_T59 | EnjuParser_T56 | arg2Of | and,on |
| EnjuParser_R58 | EnjuParser_T58 | EnjuParser_T57 | arg1Of | pathogenesis,FRDA |
| EnjuParser_R59 | EnjuParser_T58 | EnjuParser_T59 | arg1Of | pathogenesis,and |
| EnjuParser_R60 | EnjuParser_T61 | EnjuParser_T59 | arg2Of | development,and |
| EnjuParser_R61 | EnjuParser_T61 | EnjuParser_T60 | arg1Of | development,therapeutic |
| EnjuParser_R62 | EnjuParser_T55 | EnjuParser_T62 | arg1Of | studies,are |
| EnjuParser_R63 | EnjuParser_T63 | EnjuParser_T62 | arg2Of | limited,are |
| EnjuParser_R64 | EnjuParser_T66 | EnjuParser_T63 | arg1Of | availability,limited |
| EnjuParser_R65 | EnjuParser_T55 | EnjuParser_T63 | arg2Of | studies,limited |
| EnjuParser_R66 | EnjuParser_T66 | EnjuParser_T64 | arg2Of | availability,by |
| EnjuParser_R67 | EnjuParser_T66 | EnjuParser_T65 | arg1Of | availability,the |
| EnjuParser_R68 | EnjuParser_T66 | EnjuParser_T67 | arg1Of | availability,of |
| EnjuParser_R69 | EnjuParser_T71 | EnjuParser_T67 | arg2Of | model,of |
| EnjuParser_R70 | EnjuParser_T71 | EnjuParser_T68 | arg1Of | model,an |
| EnjuParser_R71 | EnjuParser_T71 | EnjuParser_T69 | arg1Of | model,appropriate |
| EnjuParser_R72 | EnjuParser_T71 | EnjuParser_T70 | arg1Of | model,cell |
| EnjuParser_R73 | EnjuParser_T66 | EnjuParser_T72 | arg1Of | availability,in |
| EnjuParser_R74 | EnjuParser_T75 | EnjuParser_T74 | arg1Of | study,to |
| EnjuParser_R75 | EnjuParser_T63 | EnjuParser_T74 | modOf | limited,to |
| EnjuParser_R76 | EnjuParser_T73 | EnjuParser_T75 | arg2Of | which,study |
| EnjuParser_R77 | EnjuParser_T77 | EnjuParser_T75 | arg3Of | mechanism,study |
| EnjuParser_R78 | EnjuParser_T77 | EnjuParser_T76 | arg1Of | mechanism,the |
| EnjuParser_R79 | EnjuParser_T77 | EnjuParser_T78 | arg1Of | mechanism,of |
| EnjuParser_R80 | EnjuParser_T79 | EnjuParser_T78 | arg2Of | instability,of |
| EnjuParser_R81 | EnjuParser_T79 | EnjuParser_T80 | arg1Of | instability,of |
| EnjuParser_R82 | EnjuParser_T84 | EnjuParser_T80 | arg2Of | repeats,of |
| EnjuParser_R83 | EnjuParser_T84 | EnjuParser_T81 | arg1Of | repeats,the |
| EnjuParser_R84 | EnjuParser_T84 | EnjuParser_T82 | arg1Of | repeats,GAA·TTC |
| EnjuParser_R85 | EnjuParser_T84 | EnjuParser_T83 | arg1Of | repeats,triplet |
| EnjuParser_R86 | EnjuParser_T84 | EnjuParser_T85 | arg1Of | repeats,in |
| EnjuParser_R87 | EnjuParser_T88 | EnjuParser_T85 | arg2Of | genome,in |
| EnjuParser_R88 | EnjuParser_T88 | EnjuParser_T86 | arg1Of | genome,the |
| EnjuParser_R89 | EnjuParser_T88 | EnjuParser_T87 | arg1Of | genome,human |
| EnjuParser_R90 | EnjuParser_T99 | EnjuParser_T89 | arg1Of | generated,Herein |
| EnjuParser_R91 | EnjuParser_T99 | EnjuParser_T90 | arg1Of | generated,"," |
| EnjuParser_R92 | EnjuParser_T94 | EnjuParser_T91 | arg2Of | cells,induced |
| EnjuParser_R93 | EnjuParser_T94 | EnjuParser_T92 | arg1Of | cells,pluripotent |
| EnjuParser_R94 | EnjuParser_T94 | EnjuParser_T93 | arg1Of | cells,stem |
| EnjuParser_R95 | EnjuParser_T94 | EnjuParser_T95 | arg1Of | cells,( |
| EnjuParser_R96 | EnjuParser_T96 | EnjuParser_T95 | arg2Of | iPSCs,( |
| EnjuParser_R97 | EnjuParser_T97 | EnjuParser_T95 | arg3Of | ),( |
| EnjuParser_R98 | EnjuParser_T94 | EnjuParser_T98 | arg1Of | cells,were |
| EnjuParser_R99 | EnjuParser_T99 | EnjuParser_T98 | arg2Of | generated,were |
| EnjuParser_R100 | EnjuParser_T94 | EnjuParser_T99 | arg2Of | cells,generated |
| EnjuParser_R101 | EnjuParser_T99 | EnjuParser_T100 | arg1Of | generated,from |
| EnjuParser_R102 | EnjuParser_T103 | EnjuParser_T100 | arg2Of | fibroblasts,from |
| EnjuParser_R103 | EnjuParser_T103 | EnjuParser_T101 | arg1Of | fibroblasts,FRDA |
| EnjuParser_R104 | EnjuParser_T103 | EnjuParser_T102 | arg1Of | fibroblasts,patient |
| EnjuParser_R105 | EnjuParser_T103 | EnjuParser_T104 | arg1Of | fibroblasts,after |
| EnjuParser_R106 | EnjuParser_T105 | EnjuParser_T104 | arg2Of | transduction,after |
| EnjuParser_R107 | EnjuParser_T105 | EnjuParser_T106 | arg1Of | transduction,with |
| EnjuParser_R108 | EnjuParser_T117 | EnjuParser_T106 | arg2Of | and,with |
| EnjuParser_R109 | EnjuParser_T110 | EnjuParser_T107 | arg1Of | factors,the |
| EnjuParser_R110 | EnjuParser_T110 | EnjuParser_T108 | arg1Of | factors,four |
| EnjuParser_R111 | EnjuParser_T110 | EnjuParser_T109 | arg1Of | factors,transcription |
| EnjuParser_R112 | EnjuParser_T117 | EnjuParser_T110 | arg1Of | and,factors |
| EnjuParser_R113 | EnjuParser_T111 | EnjuParser_T112 | arg1Of | Oct4,"," |
| EnjuParser_R114 | EnjuParser_T113 | EnjuParser_T112 | arg2Of | Sox2,"," |
| EnjuParser_R115 | EnjuParser_T112 | EnjuParser_T114 | arg1Of | ",","," |
| EnjuParser_R116 | EnjuParser_T115 | EnjuParser_T114 | arg2Of | Klf4,"," |
| EnjuParser_R117 | EnjuParser_T117 | EnjuParser_T116 | arg1Of | and,"," |
| EnjuParser_R118 | EnjuParser_T114 | EnjuParser_T117 | arg1Of | ",",and |
| EnjuParser_R119 | EnjuParser_T118 | EnjuParser_T117 | arg2Of | c-Myc.,and |
| EnjuParser_R120 | EnjuParser_T120 | EnjuParser_T119 | arg1Of | cells,These |
| EnjuParser_R121 | EnjuParser_T120 | EnjuParser_T121 | arg1Of | cells,were |
| EnjuParser_R122 | EnjuParser_T122 | EnjuParser_T121 | arg2Of | differentiated,were |
| EnjuParser_R123 | EnjuParser_T117 | EnjuParser_T121 | modOf | and,were |
| EnjuParser_R124 | EnjuParser_T120 | EnjuParser_T122 | arg2Of | cells,differentiated |
| EnjuParser_R125 | EnjuParser_T122 | EnjuParser_T123 | arg1Of | differentiated,into |
| EnjuParser_R126 | EnjuParser_T125 | EnjuParser_T123 | arg2Of | and,into |
| EnjuParser_R127 | EnjuParser_T124 | EnjuParser_T125 | arg1Of | neurospheres,and |
| EnjuParser_R128 | EnjuParser_T127 | EnjuParser_T125 | arg2Of | precursors,and |
| EnjuParser_R129 | EnjuParser_T127 | EnjuParser_T126 | arg1Of | precursors,neuronal |
| EnjuParser_R130 | EnjuParser_T129 | EnjuParser_T128 | arg1Of | vitro,in |
| EnjuParser_R131 | EnjuParser_T122 | EnjuParser_T129 | arg1Of | differentiated,vitro |
| EnjuParser_R132 | EnjuParser_T122 | EnjuParser_T130 | arg1Of | differentiated,"," |
| EnjuParser_R133 | EnjuParser_T135 | EnjuParser_T131 | arg2Of | model,providing |
| EnjuParser_R134 | EnjuParser_T122 | EnjuParser_T131 | modOf | differentiated,providing |
| EnjuParser_R135 | EnjuParser_T135 | EnjuParser_T132 | arg1Of | model,a |
| EnjuParser_R136 | EnjuParser_T135 | EnjuParser_T133 | arg1Of | model,valuable |
| EnjuParser_R137 | EnjuParser_T135 | EnjuParser_T134 | arg1Of | model,cell |
| EnjuParser_R138 | EnjuParser_T135 | EnjuParser_T136 | arg1Of | model,for |
| EnjuParser_R139 | EnjuParser_T137 | EnjuParser_T136 | arg2Of | FRDA,for |
| EnjuParser_R140 | EnjuParser_T147 | EnjuParser_T138 | arg1Of | expanded,During |
| EnjuParser_R141 | EnjuParser_T139 | EnjuParser_T138 | arg2Of | propagation,During |
| EnjuParser_R142 | EnjuParser_T139 | EnjuParser_T140 | arg1Of | propagation,of |
| EnjuParser_R143 | EnjuParser_T142 | EnjuParser_T140 | arg2Of | iPSCs,of |
| EnjuParser_R144 | EnjuParser_T142 | EnjuParser_T141 | arg1Of | iPSCs,the |
| EnjuParser_R145 | EnjuParser_T147 | EnjuParser_T143 | arg1Of | expanded,"," |
| EnjuParser_R146 | EnjuParser_T146 | EnjuParser_T144 | arg1Of | repeats,GAA·TTC |
| EnjuParser_R147 | EnjuParser_T146 | EnjuParser_T145 | arg1Of | repeats,triplet |
| EnjuParser_R148 | EnjuParser_T146 | EnjuParser_T147 | arg2Of | repeats,expanded |
| EnjuParser_R149 | EnjuParser_T147 | EnjuParser_T148 | arg1Of | expanded,at |
| EnjuParser_R150 | EnjuParser_T150 | EnjuParser_T148 | arg2Of | rate,at |
| EnjuParser_R151 | EnjuParser_T150 | EnjuParser_T149 | arg1Of | rate,a |
| EnjuParser_R152 | EnjuParser_T150 | EnjuParser_T151 | arg1Of | rate,of |
| EnjuParser_R153 | EnjuParser_T156 | EnjuParser_T151 | arg2Of | repeats/replication,of |
| EnjuParser_R154 | EnjuParser_T153 | EnjuParser_T152 | arg1Of | two,about |
| EnjuParser_R155 | EnjuParser_T156 | EnjuParser_T153 | arg1Of | repeats/replication,two |
| EnjuParser_R156 | EnjuParser_T156 | EnjuParser_T154 | arg1Of | repeats/replication,GAA·TTC |
| EnjuParser_R157 | EnjuParser_T156 | EnjuParser_T155 | arg1Of | repeats/replication,triplet |
| EnjuParser_R158 | EnjuParser_T162 | EnjuParser_T157 | arg1Of | were,However |
| EnjuParser_R159 | EnjuParser_T162 | EnjuParser_T158 | arg1Of | were,"," |
| EnjuParser_R160 | EnjuParser_T161 | EnjuParser_T159 | arg1Of | repeats,GAA·TTC |
| EnjuParser_R161 | EnjuParser_T161 | EnjuParser_T160 | arg1Of | repeats,triplet |
| EnjuParser_R162 | EnjuParser_T161 | EnjuParser_T162 | arg1Of | repeats,were |
| EnjuParser_R163 | EnjuParser_T163 | EnjuParser_T162 | arg2Of | stable,were |
| EnjuParser_R164 | EnjuParser_T161 | EnjuParser_T163 | arg1Of | repeats,stable |
| EnjuParser_R165 | EnjuParser_T163 | EnjuParser_T164 | arg1Of | stable,in |
| EnjuParser_R166 | EnjuParser_T167 | EnjuParser_T164 | arg2Of | and,in |
| EnjuParser_R167 | EnjuParser_T166 | EnjuParser_T165 | arg1Of | fibroblasts,FRDA |
| EnjuParser_R168 | EnjuParser_T166 | EnjuParser_T167 | arg1Of | fibroblasts,and |
| EnjuParser_R169 | EnjuParser_T170 | EnjuParser_T167 | arg2Of | cells,and |
| EnjuParser_R170 | EnjuParser_T170 | EnjuParser_T168 | arg1Of | cells,neuronal |
| EnjuParser_R171 | EnjuParser_T170 | EnjuParser_T169 | arg1Of | cells,stem |
| EnjuParser_R172 | EnjuParser_T174 | EnjuParser_T171 | arg1Of | enzymes,The |
| EnjuParser_R173 | EnjuParser_T174 | EnjuParser_T172 | arg1Of | enzymes,mismatch |
| EnjuParser_R174 | EnjuParser_T174 | EnjuParser_T173 | arg1Of | enzymes,repair |
| EnjuParser_R175 | EnjuParser_T179 | EnjuParser_T174 | arg1Of | and,enzymes |
| EnjuParser_R176 | EnjuParser_T175 | EnjuParser_T176 | arg1Of | MSH2,"," |
| EnjuParser_R177 | EnjuParser_T177 | EnjuParser_T176 | arg2Of | MSH3,"," |
| EnjuParser_R178 | EnjuParser_T179 | EnjuParser_T178 | arg1Of | and,"," |
| EnjuParser_R179 | EnjuParser_T176 | EnjuParser_T179 | arg1Of | ",",and |
| EnjuParser_R180 | EnjuParser_T180 | EnjuParser_T179 | arg2Of | MSH6,and |
| EnjuParser_R181 | EnjuParser_T179 | EnjuParser_T181 | arg1Of | and,"," |
| EnjuParser_R182 | EnjuParser_T179 | EnjuParser_T182 | arg2Of | and,implicated |
| EnjuParser_R183 | EnjuParser_T182 | EnjuParser_T183 | arg1Of | implicated,in |
| EnjuParser_R184 | EnjuParser_T185 | EnjuParser_T183 | arg2Of | instability,in |
| EnjuParser_R185 | EnjuParser_T185 | EnjuParser_T184 | arg1Of | instability,repeat |
| EnjuParser_R186 | EnjuParser_T182 | EnjuParser_T186 | arg1Of | implicated,in |
| EnjuParser_R187 | EnjuParser_T189 | EnjuParser_T186 | arg2Of | diseases,in |
| EnjuParser_R188 | EnjuParser_T189 | EnjuParser_T187 | arg1Of | diseases,other |
| EnjuParser_R189 | EnjuParser_T189 | EnjuParser_T188 | arg1Of | diseases,triplet-repeat |
| EnjuParser_R190 | EnjuParser_T205 | EnjuParser_T190 | arg1Of | and,"," |
| EnjuParser_R191 | EnjuParser_T179 | EnjuParser_T191 | arg1Of | and,were |
| EnjuParser_R192 | EnjuParser_T193 | EnjuParser_T191 | arg2Of | expressed,were |
| EnjuParser_R214 | EnjuParser_T219 | EnjuParser_T212 | arg1Of | impeded,"," |
| EnjuParser_R215 | EnjuParser_T214 | EnjuParser_T213 | arg1Of | silencing,shRNA |
| EnjuParser_R216 | EnjuParser_T214 | EnjuParser_T215 | arg1Of | silencing,of |
| EnjuParser_R217 | EnjuParser_T217 | EnjuParser_T215 | arg2Of | and,of |
| EnjuParser_R218 | EnjuParser_T216 | EnjuParser_T217 | arg1Of | MSH2,and |
| EnjuParser_R219 | EnjuParser_T218 | EnjuParser_T217 | arg2Of | MSH6,and |
| EnjuParser_R220 | EnjuParser_T214 | EnjuParser_T219 | arg1Of | silencing,impeded |
| EnjuParser_R221 | EnjuParser_T222 | EnjuParser_T219 | arg2Of | expansion,impeded |
| EnjuParser_R222 | EnjuParser_T222 | EnjuParser_T220 | arg1Of | expansion,GAA·TTC |
| EnjuParser_R223 | EnjuParser_T222 | EnjuParser_T221 | arg1Of | expansion,triplet-repeat |
| EnjuParser_R224 | EnjuParser_T226 | EnjuParser_T223 | arg1Of | polyamide,A |
| EnjuParser_R225 | EnjuParser_T226 | EnjuParser_T224 | arg1Of | polyamide,specific |
| EnjuParser_R226 | EnjuParser_T226 | EnjuParser_T225 | arg1Of | polyamide,pyrrole-imidazole |
| EnjuParser_R227 | EnjuParser_T226 | EnjuParser_T227 | arg1Of | polyamide,targeting |
| EnjuParser_R228 | EnjuParser_T230 | EnjuParser_T227 | arg2Of | DNA,targeting |
| EnjuParser_R229 | EnjuParser_T230 | EnjuParser_T228 | arg1Of | DNA,GAA·TTC |
| EnjuParser_R230 | EnjuParser_T230 | EnjuParser_T229 | arg1Of | DNA,triplet-repeat |
| EnjuParser_R231 | EnjuParser_T232 | EnjuParser_T231 | arg1Of | blocked,partially |
| EnjuParser_R232 | EnjuParser_T226 | EnjuParser_T232 | arg1Of | polyamide,blocked |
| EnjuParser_R233 | EnjuParser_T234 | EnjuParser_T232 | arg2Of | expansion,blocked |
| EnjuParser_R234 | EnjuParser_T234 | EnjuParser_T233 | arg1Of | expansion,repeat |
| EnjuParser_R235 | EnjuParser_T232 | EnjuParser_T235 | arg1Of | blocked,by |
| EnjuParser_R236 | EnjuParser_T236 | EnjuParser_T235 | arg2Of | displacing,by |
| EnjuParser_R237 | EnjuParser_T226 | EnjuParser_T236 | arg1Of | polyamide,displacing |
| EnjuParser_R238 | EnjuParser_T237 | EnjuParser_T236 | arg2Of | MSH2,displacing |
| EnjuParser_R239 | EnjuParser_T237 | EnjuParser_T238 | arg1Of | MSH2,from |
| EnjuParser_R240 | EnjuParser_T240 | EnjuParser_T238 | arg2Of | intron,from |
| EnjuParser_R241 | EnjuParser_T240 | EnjuParser_T239 | arg1Of | intron,FXN |
| EnjuParser_R242 | EnjuParser_T240 | EnjuParser_T241 | arg1Of | intron,1 |
| EnjuParser_R243 | EnjuParser_T240 | EnjuParser_T242 | arg1Of | intron,in |
| EnjuParser_R244 | EnjuParser_T244 | EnjuParser_T242 | arg2Of | iPSCs,in |