> top > docs > PubMed:22763039 > annotations

PubMed:22763039 JSONTXT

Annnotations TAB JSON ListView MergeView

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-92 Sentence denotes Burkholderia cenocepacia lectin A binding to heptoses from the bacterial lipopolysaccharide.
TextSentencer_T2 93-216 Sentence denotes Bacteria from the Burkholderia cepacia complex (Bcc) cause highly contagious pneumonia among cystic fibrosis (CF) patients.
TextSentencer_T3 217-367 Sentence denotes Among them, Burkholderia cenocepacia is one of the most dangerous in the Bcc and is the most frequent cause of morbidity and mortality in CF patients.
TextSentencer_T4 368-517 Sentence denotes Indeed, it is responsible of "cepacia syndrome", a deadly exacerbation of infection, that is the main cause of poor outcomes in lung transplantation.
TextSentencer_T5 518-642 Sentence denotes Burkholderia cenocepacia produces several soluble lectins with specificity for fucosylated and mannosylated glycoconjugates.
TextSentencer_T6 643-770 Sentence denotes These lectins are present on the bacterial cell surface and it has been proposed that they bind to lipopolysaccharide epitopes.
TextSentencer_T7 771-907 Sentence denotes In this work, we report on the interaction of one B. cenocepacia lectin, BC2L-A, with heptose and other manno configured sugar residues.
TextSentencer_T8 908-1129 Sentence denotes Saturation transfer difference NMR spectroscopy studies of BC2L-A with different mono- and disaccharides demonstrated the requirement of manno configuration with the hydroxyl or glycol group at C6 for the binding process.
TextSentencer_T9 1130-1344 Sentence denotes The crystal structure of BC2L-A complexed with the methyl-heptoside confirmed the location of the carbohydrate ring in the binding site and elucidated the orientation of the glycol tail, in agreement with NMR data.
TextSentencer_T10 1345-1579 Sentence denotes Titration calorimetry performed on monosaccharides, heptose disaccharides and bacterial heptose-containing oligosaccharides and polysaccharides confirmed that bacterial cell wall contains carbohydrate epitopes that can bind to BC2L-A.
TextSentencer_T11 1580-1711 Sentence denotes Additionally, the specific binding of fluorescent BC2L-A lectin on B. cenocepacia bacterial surface was demonstrated by microscopy.
T1 0-92 Sentence denotes Burkholderia cenocepacia lectin A binding to heptoses from the bacterial lipopolysaccharide.
T2 93-216 Sentence denotes Bacteria from the Burkholderia cepacia complex (Bcc) cause highly contagious pneumonia among cystic fibrosis (CF) patients.
T3 217-367 Sentence denotes Among them, Burkholderia cenocepacia is one of the most dangerous in the Bcc and is the most frequent cause of morbidity and mortality in CF patients.
T4 368-517 Sentence denotes Indeed, it is responsible of "cepacia syndrome", a deadly exacerbation of infection, that is the main cause of poor outcomes in lung transplantation.
T5 518-642 Sentence denotes Burkholderia cenocepacia produces several soluble lectins with specificity for fucosylated and mannosylated glycoconjugates.
T6 643-770 Sentence denotes These lectins are present on the bacterial cell surface and it has been proposed that they bind to lipopolysaccharide epitopes.
T7 771-907 Sentence denotes In this work, we report on the interaction of one B. cenocepacia lectin, BC2L-A, with heptose and other manno configured sugar residues.
T8 908-1129 Sentence denotes Saturation transfer difference NMR spectroscopy studies of BC2L-A with different mono- and disaccharides demonstrated the requirement of manno configuration with the hydroxyl or glycol group at C6 for the binding process.
T9 1130-1344 Sentence denotes The crystal structure of BC2L-A complexed with the methyl-heptoside confirmed the location of the carbohydrate ring in the binding site and elucidated the orientation of the glycol tail, in agreement with NMR data.
T10 1345-1711 Sentence denotes Titration calorimetry performed on monosaccharides, heptose disaccharides and bacterial heptose-containing oligosaccharides and polysaccharides confirmed that bacterial cell wall contains carbohydrate epitopes that can bind to BC2L-A. Additionally, the specific binding of fluorescent BC2L-A lectin on B. cenocepacia bacterial surface was demonstrated by microscopy.
T1 0-92 Sentence denotes Burkholderia cenocepacia lectin A binding to heptoses from the bacterial lipopolysaccharide.
T2 93-216 Sentence denotes Bacteria from the Burkholderia cepacia complex (Bcc) cause highly contagious pneumonia among cystic fibrosis (CF) patients.
T3 217-367 Sentence denotes Among them, Burkholderia cenocepacia is one of the most dangerous in the Bcc and is the most frequent cause of morbidity and mortality in CF patients.
T4 368-517 Sentence denotes Indeed, it is responsible of "cepacia syndrome", a deadly exacerbation of infection, that is the main cause of poor outcomes in lung transplantation.
T5 518-642 Sentence denotes Burkholderia cenocepacia produces several soluble lectins with specificity for fucosylated and mannosylated glycoconjugates.
T6 643-770 Sentence denotes These lectins are present on the bacterial cell surface and it has been proposed that they bind to lipopolysaccharide epitopes.
T7 771-907 Sentence denotes In this work, we report on the interaction of one B. cenocepacia lectin, BC2L-A, with heptose and other manno configured sugar residues.
T8 908-1129 Sentence denotes Saturation transfer difference NMR spectroscopy studies of BC2L-A with different mono- and disaccharides demonstrated the requirement of manno configuration with the hydroxyl or glycol group at C6 for the binding process.
T9 1130-1344 Sentence denotes The crystal structure of BC2L-A complexed with the methyl-heptoside confirmed the location of the carbohydrate ring in the binding site and elucidated the orientation of the glycol tail, in agreement with NMR data.
T10 1345-1579 Sentence denotes Titration calorimetry performed on monosaccharides, heptose disaccharides and bacterial heptose-containing oligosaccharides and polysaccharides confirmed that bacterial cell wall contains carbohydrate epitopes that can bind to BC2L-A.
T11 1580-1711 Sentence denotes Additionally, the specific binding of fluorescent BC2L-A lectin on B. cenocepacia bacterial surface was demonstrated by microscopy.

Glycosmos6-MAT

Id Subject Object Predicate Lexical cue
T1 496-500 http://purl.obolibrary.org/obo/MAT_0000135 denotes lung

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 170-179 HP_0002090 denotes pneumonia
T2 419-425 HP_0000365 denotes deadly

GlycoBiology-PACDB

Id Subject Object Predicate Lexical cue
_T1 0-24 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC347 denotes Burkholderia cenocepacia
_T2 0-24 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC065 denotes Burkholderia cenocepacia
_T3 0-24 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC372 denotes Burkholderia cenocepacia
_T4 0-24 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC420 denotes Burkholderia cenocepacia
_T5 0-24 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC096 denotes Burkholderia cenocepacia
_T6 0-24 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC385 denotes Burkholderia cenocepacia
_T7 0-24 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC464 denotes Burkholderia cenocepacia
_T8 111-131 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC372 denotes Burkholderia cepacia
_T9 111-131 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC096 denotes Burkholderia cepacia
_T10 111-131 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC385 denotes Burkholderia cepacia
_T11 111-131 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC065 denotes Burkholderia cepacia
_T12 111-131 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC420 denotes Burkholderia cepacia
_T13 111-131 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC347 denotes Burkholderia cepacia
_T14 111-131 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC464 denotes Burkholderia cepacia
_T15 229-253 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC096 denotes Burkholderia cenocepacia
_T16 229-253 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC464 denotes Burkholderia cenocepacia
_T17 229-253 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC372 denotes Burkholderia cenocepacia
_T18 229-253 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC347 denotes Burkholderia cenocepacia
_T19 229-253 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC420 denotes Burkholderia cenocepacia
_T20 229-253 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC385 denotes Burkholderia cenocepacia
_T21 229-253 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC065 denotes Burkholderia cenocepacia
_T22 518-542 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC420 denotes Burkholderia cenocepacia
_T23 518-542 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC065 denotes Burkholderia cenocepacia
_T24 518-542 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC464 denotes Burkholderia cenocepacia
_T25 518-542 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC385 denotes Burkholderia cenocepacia
_T26 518-542 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC096 denotes Burkholderia cenocepacia
_T27 518-542 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC347 denotes Burkholderia cenocepacia
_T28 518-542 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC372 denotes Burkholderia cenocepacia

ICD10

Id Subject Object Predicate Lexical cue
T1 170-179 http://purl.bioontology.org/ontology/ICD10/J18.9 denotes pneumonia
T2 186-201 http://purl.bioontology.org/ontology/ICD10/E84 denotes cystic fibrosis
T3 186-201 http://purl.bioontology.org/ontology/ICD10/E84.9 denotes cystic fibrosis
T4 319-351 http://purl.bioontology.org/ontology/ICD10/V01-Y98.9 denotes cause of morbidity and mortality

GlycoBiology-FMA

Id Subject Object Predicate Lexical cue
_T1 73-91 FMAID:196735 denotes lipopolysaccharide
_T2 73-91 FMAID:82746 denotes lipopolysaccharide
_T3 73-91 FMAID:82785 denotes lipopolysaccharide
_T4 73-91 FMAID:196779 denotes lipopolysaccharide
_T5 465-469 FMAID:214734 denotes main
_T6 496-500 FMAID:169341 denotes lung
_T7 496-500 FMAID:7195 denotes lung
_T8 496-500 FMAID:93670 denotes lung
_T9 626-641 FMAID:196776 denotes glycoconjugates
_T10 626-641 FMAID:82782 denotes glycoconjugates
_T11 686-698 FMAID:200942 denotes cell surface
_T12 686-698 FMAID:212684 denotes cell surface
_T13 691-698 FMAID:50594 denotes surface
_T14 691-698 FMAID:146300 denotes surface
_T15 742-760 FMAID:196735 denotes lipopolysaccharide
_T16 742-760 FMAID:82746 denotes lipopolysaccharide
_T17 742-760 FMAID:82785 denotes lipopolysaccharide
_T18 742-760 FMAID:196779 denotes lipopolysaccharide
_T19 875-880 FMAID:226916 denotes manno
_T20 892-897 FMAID:196724 denotes sugar
_T21 999-1012 FMAID:82744 denotes disaccharides
_T22 999-1012 FMAID:196733 denotes disaccharides
_T23 1045-1050 FMAID:226916 denotes manno
_T24 1102-1104 FMAID:63499 denotes C6
_T25 1102-1104 FMAID:167724 denotes C6
_T26 1228-1240 FMAID:197276 denotes carbohydrate
_T27 1228-1240 FMAID:82737 denotes carbohydrate
_T28 1311-1315 FMAID:228776 denotes tail
_T29 1380-1395 FMAID:196730 denotes monosaccharides
_T30 1380-1395 FMAID:82741 denotes monosaccharides
_T31 1405-1418 FMAID:196733 denotes disaccharides
_T32 1405-1418 FMAID:82744 denotes disaccharides
_T33 1452-1468 FMAID:196731 denotes oligosaccharides
_T34 1452-1468 FMAID:82742 denotes oligosaccharides
_T35 1473-1488 FMAID:82785 denotes polysaccharides
_T36 1473-1488 FMAID:196735 denotes polysaccharides
_T37 1473-1488 FMAID:82746 denotes polysaccharides
_T38 1473-1488 FMAID:196779 denotes polysaccharides
_T39 1533-1545 FMAID:82737 denotes carbohydrate
_T40 1533-1545 FMAID:197276 denotes carbohydrate
_T41 1672-1679 FMAID:50594 denotes surface
_T42 1672-1679 FMAID:146300 denotes surface

uniprot-human

Id Subject Object Predicate Lexical cue
T1 1102-1104 http://www.uniprot.org/uniprot/P13671 denotes C6

GlycoBiology-NCBITAXON

Id Subject Object Predicate Lexical cue
T1 0-12 http://purl.bioontology.org/ontology/NCBITAXON/219649 denotes Burkholderia
T2 0-12 http://purl.bioontology.org/ontology/NCBITAXON/386056 denotes Burkholderia
T3 0-12 http://purl.bioontology.org/ontology/NCBITAXON/32008 denotes Burkholderia
T4 0-12 http://purl.bioontology.org/ontology/NCBITAXON/311230 denotes Burkholderia
T5 0-12 http://purl.bioontology.org/ontology/NCBITAXON/948107 denotes Burkholderia
T6 0-12 http://purl.bioontology.org/ontology/NCBITAXON/634127 denotes Burkholderia
T7 0-12 http://purl.bioontology.org/ontology/NCBITAXON/337 denotes Burkholderia
T8 0-12 http://purl.bioontology.org/ontology/NCBITAXON/482957 denotes Burkholderia
T9 0-24 http://purl.bioontology.org/ontology/NCBITAXON/215535 denotes Burkholderia cenocepacia
T10 0-24 http://purl.bioontology.org/ontology/NCBITAXON/292 denotes Burkholderia cenocepacia
T11 93-101 http://purl.bioontology.org/ontology/NCBITAXON/629395 denotes Bacteria
T12 93-101 http://purl.bioontology.org/ontology/NCBITAXON/2 denotes Bacteria
T13 111-123 http://purl.bioontology.org/ontology/NCBITAXON/337 denotes Burkholderia
T14 111-123 http://purl.bioontology.org/ontology/NCBITAXON/311230 denotes Burkholderia
T15 111-123 http://purl.bioontology.org/ontology/NCBITAXON/32008 denotes Burkholderia
T16 111-123 http://purl.bioontology.org/ontology/NCBITAXON/948107 denotes Burkholderia
T17 111-123 http://purl.bioontology.org/ontology/NCBITAXON/634127 denotes Burkholderia
T18 111-123 http://purl.bioontology.org/ontology/NCBITAXON/482957 denotes Burkholderia
T19 111-123 http://purl.bioontology.org/ontology/NCBITAXON/219649 denotes Burkholderia
T20 111-123 http://purl.bioontology.org/ontology/NCBITAXON/386056 denotes Burkholderia
T21 111-131 http://purl.bioontology.org/ontology/NCBITAXON/292 denotes Burkholderia cepacia
T22 111-131 http://purl.bioontology.org/ontology/NCBITAXON/215535 denotes Burkholderia cepacia
T23 111-139 http://purl.bioontology.org/ontology/NCBITAXON/87882 denotes Burkholderia cepacia complex
T24 229-241 http://purl.bioontology.org/ontology/NCBITAXON/948107 denotes Burkholderia
T25 229-241 http://purl.bioontology.org/ontology/NCBITAXON/219649 denotes Burkholderia
T26 229-241 http://purl.bioontology.org/ontology/NCBITAXON/634127 denotes Burkholderia
T27 229-241 http://purl.bioontology.org/ontology/NCBITAXON/311230 denotes Burkholderia
T28 229-241 http://purl.bioontology.org/ontology/NCBITAXON/337 denotes Burkholderia
T29 229-241 http://purl.bioontology.org/ontology/NCBITAXON/386056 denotes Burkholderia
T30 229-241 http://purl.bioontology.org/ontology/NCBITAXON/482957 denotes Burkholderia
T31 229-241 http://purl.bioontology.org/ontology/NCBITAXON/32008 denotes Burkholderia
T32 229-253 http://purl.bioontology.org/ontology/NCBITAXON/215535 denotes Burkholderia cenocepacia
T33 229-253 http://purl.bioontology.org/ontology/NCBITAXON/292 denotes Burkholderia cenocepacia
T34 518-530 http://purl.bioontology.org/ontology/NCBITAXON/219649 denotes Burkholderia
T35 518-530 http://purl.bioontology.org/ontology/NCBITAXON/948107 denotes Burkholderia
T36 518-530 http://purl.bioontology.org/ontology/NCBITAXON/386056 denotes Burkholderia
T37 518-530 http://purl.bioontology.org/ontology/NCBITAXON/482957 denotes Burkholderia
T38 518-530 http://purl.bioontology.org/ontology/NCBITAXON/32008 denotes Burkholderia
T39 518-530 http://purl.bioontology.org/ontology/NCBITAXON/311230 denotes Burkholderia
T40 518-530 http://purl.bioontology.org/ontology/NCBITAXON/634127 denotes Burkholderia
T41 518-530 http://purl.bioontology.org/ontology/NCBITAXON/337 denotes Burkholderia
T42 518-542 http://purl.bioontology.org/ontology/NCBITAXON/215535 denotes Burkholderia cenocepacia
T43 518-542 http://purl.bioontology.org/ontology/NCBITAXON/292 denotes Burkholderia cenocepacia
T44 1093-1098 http://purl.bioontology.org/ontology/STY/T096 denotes group

GO-BP

Id Subject Object Predicate Lexical cue
T1 597-608 http://purl.obolibrary.org/obo/GO_0036065 denotes fucosylated
T2 613-625 http://purl.obolibrary.org/obo/GO_0097502 denotes mannosylated
T3 1181-1187 http://purl.obolibrary.org/obo/GO_0032259 denotes methyl

GO-MF

Id Subject Object Predicate Lexical cue
T1 34-41 http://purl.obolibrary.org/obo/GO_0070026 denotes binding
T2 1113-1120 http://purl.obolibrary.org/obo/GO_0070026 denotes binding
T3 1253-1260 http://purl.obolibrary.org/obo/GO_0070026 denotes binding
T4 734-738 http://purl.obolibrary.org/obo/GO_0070026 denotes bind
T5 1564-1568 http://purl.obolibrary.org/obo/GO_0070026 denotes bind
T6 34-41 http://purl.obolibrary.org/obo/GO_0003680 denotes binding
T7 1113-1120 http://purl.obolibrary.org/obo/GO_0003680 denotes binding
T8 1253-1260 http://purl.obolibrary.org/obo/GO_0003680 denotes binding
T9 734-738 http://purl.obolibrary.org/obo/GO_0003680 denotes bind
T10 1564-1568 http://purl.obolibrary.org/obo/GO_0003680 denotes bind
T11 34-41 http://purl.obolibrary.org/obo/GO_0017091 denotes binding
T12 1113-1120 http://purl.obolibrary.org/obo/GO_0017091 denotes binding
T13 1253-1260 http://purl.obolibrary.org/obo/GO_0017091 denotes binding
T14 734-738 http://purl.obolibrary.org/obo/GO_0017091 denotes bind
T15 1564-1568 http://purl.obolibrary.org/obo/GO_0017091 denotes bind
T16 34-41 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T17 1113-1120 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T18 1253-1260 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T19 734-738 http://purl.obolibrary.org/obo/GO_0005488 denotes bind
T20 1564-1568 http://purl.obolibrary.org/obo/GO_0005488 denotes bind
T21 734-760 http://purl.obolibrary.org/obo/GO_0001530 denotes bind to lipopolysaccharide

GO-CC

Id Subject Object Predicate Lexical cue
T1 686-690 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T2 1514-1518 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T3 686-698 http://purl.obolibrary.org/obo/GO_0009986 denotes cell surface
T4 1514-1523 http://purl.obolibrary.org/obo/GO_0005618 denotes cell wall
T5 1514-1532 http://purl.obolibrary.org/obo/GO_0009277 denotes cell wall contains

UBERON-AE

Id Subject Object Predicate Lexical cue
T1 496-500 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T2 1311-1315 http://purl.obolibrary.org/obo/UBERON_0002415 denotes tail

Allie

Id Subject Object Predicate Lexical cue
SS1_22763039_1_0 111-139 expanded denotes Burkholderia cepacia complex
SS2_22763039_1_0 141-144 abbr denotes Bcc
SS1_22763039_1_1 186-201 expanded denotes cystic fibrosis
SS2_22763039_1_1 203-205 abbr denotes CF
AE1_22763039_1_0 SS1_22763039_1_0 SS2_22763039_1_0 abbreviatedTo Burkholderia cepacia complex,Bcc
AE1_22763039_1_1 SS1_22763039_1_1 SS2_22763039_1_1 abbreviatedTo cystic fibrosis,CF

GlyTouCan-IUPAC

Id Subject Object Predicate Lexical cue
GlycanIUPAC_T1 892-897 "http://rdf.glycoinfo.org/glycan/G59665TO" denotes sugar
GlycanIUPAC_T2 892-897 "http://rdf.glycoinfo.org/glycan/G32915EI" denotes sugar
GlycanIUPAC_T3 892-897 "http://rdf.glycoinfo.org/glycan/G60625TS" denotes sugar

GlycoBiology-MAT

Id Subject Object Predicate Lexical cue
T1 496-500 http://purl.obolibrary.org/obo/MAT_0000135 denotes lung

GlycoBiology-Epitope

Id Subject Object Predicate Lexical cue
PD-GlycoEpitope-B_T1 1102-1104 http://www.glycoepitope.jp/epitopes/AN0329 denotes C6

performance-test

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 496-500 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
PD-UBERON-AE-B_T2 1311-1315 http://purl.obolibrary.org/obo/UBERON_0002415 denotes tail

HP-phenotype

Id Subject Object Predicate Lexical cue hp_id
T1 170-179 Phenotype denotes pneumonia HP:0002090

mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 170-179 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T2 186-201 Disease denotes cystic fibrosis http://purl.obolibrary.org/obo/MONDO_0009061
T3 203-205 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T4 355-357 Disease denotes CF http://purl.obolibrary.org/obo/MONDO_0009061
T5 442-451 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550

Lectin-Jamboree-Sentence

Id Subject Object Predicate Lexical cue
T1 0-92 Sentence denotes Burkholderia cenocepacia lectin A binding to heptoses from the bacterial lipopolysaccharide.
T2 93-216 Sentence denotes Bacteria from the Burkholderia cepacia complex (Bcc) cause highly contagious pneumonia among cystic fibrosis (CF) patients.
T3 217-367 Sentence denotes Among them, Burkholderia cenocepacia is one of the most dangerous in the Bcc and is the most frequent cause of morbidity and mortality in CF patients.
T4 368-517 Sentence denotes Indeed, it is responsible of "cepacia syndrome", a deadly exacerbation of infection, that is the main cause of poor outcomes in lung transplantation.
T5 518-642 Sentence denotes Burkholderia cenocepacia produces several soluble lectins with specificity for fucosylated and mannosylated glycoconjugates.
T6 643-770 Sentence denotes These lectins are present on the bacterial cell surface and it has been proposed that they bind to lipopolysaccharide epitopes.
T7 771-907 Sentence denotes In this work, we report on the interaction of one B. cenocepacia lectin, BC2L-A, with heptose and other manno configured sugar residues.
T8 908-1129 Sentence denotes Saturation transfer difference NMR spectroscopy studies of BC2L-A with different mono- and disaccharides demonstrated the requirement of manno configuration with the hydroxyl or glycol group at C6 for the binding process.
T9 1130-1344 Sentence denotes The crystal structure of BC2L-A complexed with the methyl-heptoside confirmed the location of the carbohydrate ring in the binding site and elucidated the orientation of the glycol tail, in agreement with NMR data.
T10 1345-1711 Sentence denotes Titration calorimetry performed on monosaccharides, heptose disaccharides and bacterial heptose-containing oligosaccharides and polysaccharides confirmed that bacterial cell wall contains carbohydrate epitopes that can bind to BC2L-A. Additionally, the specific binding of fluorescent BC2L-A lectin on B. cenocepacia bacterial surface was demonstrated by microscopy.

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 0-24 OrganismTaxon denotes Burkholderia cenocepacia 95486
T2 93-101 OrganismTaxon denotes Bacteria 2|629395
T4 111-139 OrganismTaxon denotes Burkholderia cepacia complex 87882
T5 141-144 OrganismTaxon denotes Bcc 87882
T6 229-253 OrganismTaxon denotes Burkholderia cenocepacia 95486
T7 290-293 OrganismTaxon denotes Bcc 87882
T8 518-542 OrganismTaxon denotes Burkholderia cenocepacia 95486

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 496-500 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T2 1311-1315 Body_part denotes tail http://purl.obolibrary.org/obo/UBERON_0002415|http://purl.obolibrary.org/obo/UBERON_4000164
T4 1519-1523 Body_part denotes wall http://purl.obolibrary.org/obo/UBERON_0000060

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 496-500 Body_part denotes lung http://purl.obolibrary.org/obo/MAT_0000135