PubMed:22735313 / 1526-1763 JSONTXT

{"project":"Glycan-Motif","denotations":[{"id":"T38","span":{"begin":223,"end":227},"obj":"https://glytoucan.org/Structures/Glycans/G46677TE"},{"id":"T39","span":{"begin":223,"end":227},"obj":"https://glytoucan.org/Structures/Glycans/G69277LC"},{"id":"T40","span":{"begin":232,"end":236},"obj":"https://glytoucan.org/Structures/Glycans/G05952XV"},{"id":"T41","span":{"begin":232,"end":236},"obj":"https://glytoucan.org/Structures/Glycans/G40183QN"}],"text":"We conclude that the St3gal2 and St3gal3 gene products (ST3Gal-II and ST3Gal-III sialyltransferases) are largely responsible for ganglioside terminal α2-3 sialylation in the brain, synthesizing the major brain gangliosides GD1a and GT1b."}

{"project":"GlyCosmos6-Glycan-Motif-Image","denotations":[{"id":"T38","span":{"begin":223,"end":227},"obj":"Glycan_Motif"},{"id":"T40","span":{"begin":232,"end":236},"obj":"Glycan_Motif"}],"attributes":[{"id":"A38","pred":"image","subj":"T38","obj":"https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G69277LC"},{"id":"A39","pred":"image","subj":"T38","obj":"https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G46677TE"},{"id":"A40","pred":"image","subj":"T40","obj":"https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G40183QN"},{"id":"A41","pred":"image","subj":"T40","obj":"https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G05952XV"}],"text":"We conclude that the St3gal2 and St3gal3 gene products (ST3Gal-II and ST3Gal-III sialyltransferases) are largely responsible for ganglioside terminal α2-3 sialylation in the brain, synthesizing the major brain gangliosides GD1a and GT1b."}

{"project":"Glycosmos6-GlycoEpitope","denotations":[{"id":"T15","span":{"begin":223,"end":227},"obj":"http://www.glycoepitope.jp/epitopes/EP0056"},{"id":"T16","span":{"begin":232,"end":236},"obj":"http://www.glycoepitope.jp/epitopes/EP0067"}],"text":"We conclude that the St3gal2 and St3gal3 gene products (ST3Gal-II and ST3Gal-III sialyltransferases) are largely responsible for ganglioside terminal α2-3 sialylation in the brain, synthesizing the major brain gangliosides GD1a and GT1b."}

{"project":"sentences","denotations":[{"id":"TextSentencer_T12","span":{"begin":0,"end":237},"obj":"Sentence"},{"id":"T12","span":{"begin":0,"end":237},"obj":"Sentence"},{"id":"T12","span":{"begin":0,"end":237},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"We conclude that the St3gal2 and St3gal3 gene products (ST3Gal-II and ST3Gal-III sialyltransferases) are largely responsible for ganglioside terminal α2-3 sialylation in the brain, synthesizing the major brain gangliosides GD1a and GT1b."}

{"project":"GlyCosmos6-Glycan-Motif-Structure","denotations":[{"id":"T38","span":{"begin":223,"end":227},"obj":"https://glytoucan.org/Structures/Glycans/G46677TE"},{"id":"T39","span":{"begin":223,"end":227},"obj":"https://glytoucan.org/Structures/Glycans/G69277LC"},{"id":"T40","span":{"begin":232,"end":236},"obj":"https://glytoucan.org/Structures/Glycans/G05952XV"},{"id":"T41","span":{"begin":232,"end":236},"obj":"https://glytoucan.org/Structures/Glycans/G40183QN"}],"text":"We conclude that the St3gal2 and St3gal3 gene products (ST3Gal-II and ST3Gal-III sialyltransferases) are largely responsible for ganglioside terminal α2-3 sialylation in the brain, synthesizing the major brain gangliosides GD1a and GT1b."}

{"project":"Glycosmos6-MAT","denotations":[{"id":"T7","span":{"begin":174,"end":179},"obj":"http://purl.obolibrary.org/obo/MAT_0000098"},{"id":"T8","span":{"begin":204,"end":209},"obj":"http://purl.obolibrary.org/obo/MAT_0000098"}],"text":"We conclude that the St3gal2 and St3gal3 gene products (ST3Gal-II and ST3Gal-III sialyltransferases) are largely responsible for ganglioside terminal α2-3 sialylation in the brain, synthesizing the major brain gangliosides GD1a and GT1b."}

{"project":"GlyCosmos15-Glycan","denotations":[{"id":"T16","span":{"begin":223,"end":227},"obj":"Glycan"},{"id":"T17","span":{"begin":232,"end":236},"obj":"Glycan"}],"attributes":[{"id":"A16","pred":"glycosmos_id","subj":"T16","obj":"https://glycosmos.org/glycans/show/G46677TE"},{"id":"A17","pred":"glycosmos_id","subj":"T17","obj":"https://glycosmos.org/glycans/show/G40183QN"}],"text":"We conclude that the St3gal2 and St3gal3 gene products (ST3Gal-II and ST3Gal-III sialyltransferases) are largely responsible for ganglioside terminal α2-3 sialylation in the brain, synthesizing the major brain gangliosides GD1a and GT1b."}

{"project":"GlycoBiology-GDGDB","denotations":[{"id":"_T3","span":{"begin":33,"end":40},"obj":"http://acgg.asia/db/diseases/gdgdb?con_ui=CON00630"}],"text":"We conclude that the St3gal2 and St3gal3 gene products (ST3Gal-II and ST3Gal-III sialyltransferases) are largely responsible for ganglioside terminal α2-3 sialylation in the brain, synthesizing the major brain gangliosides GD1a and GT1b."}

{"project":"GlycoBiology-FMA","denotations":[{"id":"_T65","span":{"begin":41,"end":45},"obj":"FMAID:198663"},{"id":"_T66","span":{"begin":129,"end":140},"obj":"FMAID:82816"},{"id":"_T67","span":{"begin":129,"end":140},"obj":"FMAID:196811"},{"id":"_T68","span":{"begin":129,"end":149},"obj":"FMAID:218654"},{"id":"_T69","span":{"begin":174,"end":179},"obj":"FMAID:146514"},{"id":"_T70","span":{"begin":174,"end":179},"obj":"FMAID:50801"},{"id":"_T71","span":{"begin":204,"end":209},"obj":"FMAID:50801"},{"id":"_T72","span":{"begin":204,"end":209},"obj":"FMAID:146514"},{"id":"_T73","span":{"begin":210,"end":222},"obj":"FMAID:196811"},{"id":"_T74","span":{"begin":210,"end":222},"obj":"FMAID:82816"}],"namespaces":[{"prefix":"FMAID","uri":"http://purl.org/sig/ont/fma/fma"}],"text":"We conclude that the St3gal2 and St3gal3 gene products (ST3Gal-II and ST3Gal-III sialyltransferases) are largely responsible for ganglioside terminal α2-3 sialylation in the brain, synthesizing the major brain gangliosides GD1a and GT1b."}

{"project":"uniprot-human","denotations":[{"id":"T1","span":{"begin":56,"end":65},"obj":"http://www.uniprot.org/uniprot/Q16842"},{"id":"T2","span":{"begin":70,"end":80},"obj":"http://www.uniprot.org/uniprot/Q8IX54"}],"text":"We conclude that the St3gal2 and St3gal3 gene products (ST3Gal-II and ST3Gal-III sialyltransferases) are largely responsible for ganglioside terminal α2-3 sialylation in the brain, synthesizing the major brain gangliosides GD1a and GT1b."}

{"project":"uniprot-mouse","denotations":[{"id":"T9","span":{"begin":21,"end":28},"obj":"http://www.uniprot.org/uniprot/Q11204"},{"id":"T10","span":{"begin":56,"end":65},"obj":"http://www.uniprot.org/uniprot/Q11204"},{"id":"T13","span":{"begin":33,"end":40},"obj":"http://www.uniprot.org/uniprot/P97325"},{"id":"T14","span":{"begin":70,"end":80},"obj":"http://www.uniprot.org/uniprot/P97325"}],"text":"We conclude that the St3gal2 and St3gal3 gene products (ST3Gal-II and ST3Gal-III sialyltransferases) are largely responsible for ganglioside terminal α2-3 sialylation in the brain, synthesizing the major brain gangliosides GD1a and GT1b."}

{"project":"GO-BP","denotations":[{"id":"T7","span":{"begin":155,"end":166},"obj":"http://purl.obolibrary.org/obo/GO_0097503"}],"text":"We conclude that the St3gal2 and St3gal3 gene products (ST3Gal-II and ST3Gal-III sialyltransferases) are largely responsible for ganglioside terminal α2-3 sialylation in the brain, synthesizing the major brain gangliosides GD1a and GT1b."}

{"project":"UBERON-AE","denotations":[{"id":"T4","span":{"begin":174,"end":179},"obj":"http://purl.obolibrary.org/obo/UBERON_0000955"},{"id":"T5","span":{"begin":204,"end":209},"obj":"http://purl.obolibrary.org/obo/UBERON_0000955"}],"text":"We conclude that the St3gal2 and St3gal3 gene products (ST3Gal-II and ST3Gal-III sialyltransferases) are largely responsible for ganglioside terminal α2-3 sialylation in the brain, synthesizing the major brain gangliosides GD1a and GT1b."}

{"project":"GlycoBiology-MAT","denotations":[{"id":"T7","span":{"begin":174,"end":179},"obj":"http://purl.obolibrary.org/obo/MAT_0000098"},{"id":"T8","span":{"begin":204,"end":209},"obj":"http://purl.obolibrary.org/obo/MAT_0000098"}],"text":"We conclude that the St3gal2 and St3gal3 gene products (ST3Gal-II and ST3Gal-III sialyltransferases) are largely responsible for ganglioside terminal α2-3 sialylation in the brain, synthesizing the major brain gangliosides GD1a and GT1b."}

{"project":"GlycoBiology-Epitope","denotations":[{"id":"PD-GlycoEpitope-B_T8","span":{"begin":223,"end":227},"obj":"http://www.glycoepitope.jp/epitopes/EP0056"},{"id":"PD-GlycoEpitope-B_T14","span":{"begin":232,"end":236},"obj":"http://www.glycoepitope.jp/epitopes/EP0067"}],"text":"We conclude that the St3gal2 and St3gal3 gene products (ST3Gal-II and ST3Gal-III sialyltransferases) are largely responsible for ganglioside terminal α2-3 sialylation in the brain, synthesizing the major brain gangliosides GD1a and GT1b."}

{"project":"performance-test","denotations":[{"id":"PD-UBERON-AE-B_T7","span":{"begin":174,"end":179},"obj":"http://purl.obolibrary.org/obo/UBERON_0000955"},{"id":"PD-UBERON-AE-B_T8","span":{"begin":204,"end":209},"obj":"http://purl.obolibrary.org/obo/UBERON_0000955"}],"text":"We conclude that the St3gal2 and St3gal3 gene products (ST3Gal-II and ST3Gal-III sialyltransferases) are largely responsible for ganglioside terminal α2-3 sialylation in the brain, synthesizing the major brain gangliosides GD1a and GT1b."}

{"project":"Glycosmos15-GlycoEpitope","denotations":[{"id":"T15","span":{"begin":223,"end":227},"obj":"http://purl.jp/bio/12/glyco/glycan#Glycan_epitope"},{"id":"T16","span":{"begin":232,"end":236},"obj":"http://purl.jp/bio/12/glyco/glycan#Glycan_epitope"}],"attributes":[{"id":"A15","pred":"glycoepitope_id","subj":"T15","obj":"http://www.glycoepitope.jp/epitopes/EP0056"},{"id":"A16","pred":"glycoepitope_id","subj":"T16","obj":"http://www.glycoepitope.jp/epitopes/EP0067"}],"text":"We conclude that the St3gal2 and St3gal3 gene products (ST3Gal-II and ST3Gal-III sialyltransferases) are largely responsible for ganglioside terminal α2-3 sialylation in the brain, synthesizing the major brain gangliosides GD1a and GT1b."}

{"project":"Anatomy-UBERON","denotations":[{"id":"T9","span":{"begin":174,"end":179},"obj":"Body_part"},{"id":"T11","span":{"begin":204,"end":209},"obj":"Body_part"}],"attributes":[{"id":"A9","pred":"uberon_id","subj":"T9","obj":"http://purl.obolibrary.org/obo/UBERON_0000955"},{"id":"A10","pred":"uberon_id","subj":"T9","obj":"http://purl.obolibrary.org/obo/UBERON_6110636"},{"id":"A11","pred":"uberon_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/UBERON_0000955"},{"id":"A12","pred":"uberon_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/UBERON_6110636"}],"text":"We conclude that the St3gal2 and St3gal3 gene products (ST3Gal-II and ST3Gal-III sialyltransferases) are largely responsible for ganglioside terminal α2-3 sialylation in the brain, synthesizing the major brain gangliosides GD1a and GT1b."}

{"project":"Anatomy-MAT","denotations":[{"id":"T7","span":{"begin":174,"end":179},"obj":"Body_part"},{"id":"T8","span":{"begin":204,"end":209},"obj":"Body_part"}],"attributes":[{"id":"A7","pred":"mat_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/MAT_0000098"},{"id":"A8","pred":"mat_id","subj":"T8","obj":"http://purl.obolibrary.org/obo/MAT_0000098"}],"text":"We conclude that the St3gal2 and St3gal3 gene products (ST3Gal-II and ST3Gal-III sialyltransferases) are largely responsible for ganglioside terminal α2-3 sialylation in the brain, synthesizing the major brain gangliosides GD1a and GT1b."}