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Allie

Id Subject Object Predicate Lexical cue
SS1_22689120_1_0 144-162 expanded denotes Endothelial lipase
SS2_22689120_1_0 164-166 abbr denotes EL
SS1_22689120_2_0 289-313 expanded denotes high density lipoprotein
SS2_22689120_2_0 315-318 abbr denotes HDL
AE1_22689120_1_0 SS1_22689120_1_0 SS2_22689120_1_0 abbreviatedTo Endothelial lipase,EL
AE1_22689120_2_0 SS1_22689120_2_0 SS2_22689120_2_0 abbreviatedTo high density lipoprotein,HDL

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 491-496 HP_0002664 denotes tumor
T2 1203-1218 HP_0002621 denotes atherosclerosis

Inflammaging

Id Subject Object Predicate Lexical cue
T1 0-50 Sentence denotes [The role of endothelial lipase in atherogenesis].
T2 51-143 Sentence denotes Lipasa endotelial y su relación con la enfermedad cardiovascular y diabetes mellitus tipo 2.
T3 144-258 Sentence denotes Endothelial lipase (EL) is synthetized by endothelial cells and its main substrates are lipoprotein phospholipids.
T4 259-372 Sentence denotes Over expression of EL reduces high density lipoprotein (HDL) cholesterol and phospholipids, in vivo and in vitro.
T5 373-428 Sentence denotes Inhibition of the enzyme achieves the opposite effects.
T6 429-515 Sentence denotes The synthesis of the enzyme is regulated by interleukin 1 and tumor necrosis factor a.
T7 516-590 Sentence denotes These inflammatory cytokines play a role in diabetes and vascular disease.
T8 591-703 Sentence denotes An increase in vascular mechanical forces, that play a role in atherogenesis, also increase the synthesis of EL.
T9 704-839 Sentence denotes There is expression of EL in endothelial cells, macrophages and muscle cells of atherosclerotic lesions of coronary arteries of humans.
T10 840-915 Sentence denotes This evidence leads to the suspicion that EL plays a role in atherogenesis.
T11 916-1062 Sentence denotes There are also higher plasma levels of EL in subjects with type 2 diabetes, who are especially susceptible to the development of vascular lesions.
T12 1063-1219 Sentence denotes Therefore the inhibition of EL could play an important role in HDL metabolism and could be a new therapeutic strategy for the prevention of atherosclerosis.
T1 0-50 Sentence denotes [The role of endothelial lipase in atherogenesis].
T2 51-143 Sentence denotes Lipasa endotelial y su relación con la enfermedad cardiovascular y diabetes mellitus tipo 2.
T3 144-258 Sentence denotes Endothelial lipase (EL) is synthetized by endothelial cells and its main substrates are lipoprotein phospholipids.
T4 259-372 Sentence denotes Over expression of EL reduces high density lipoprotein (HDL) cholesterol and phospholipids, in vivo and in vitro.
T5 373-428 Sentence denotes Inhibition of the enzyme achieves the opposite effects.
T6 429-515 Sentence denotes The synthesis of the enzyme is regulated by interleukin 1 and tumor necrosis factor a.
T7 516-590 Sentence denotes These inflammatory cytokines play a role in diabetes and vascular disease.
T8 591-703 Sentence denotes An increase in vascular mechanical forces, that play a role in atherogenesis, also increase the synthesis of EL.
T9 704-839 Sentence denotes There is expression of EL in endothelial cells, macrophages and muscle cells of atherosclerotic lesions of coronary arteries of humans.
T10 840-915 Sentence denotes This evidence leads to the suspicion that EL plays a role in atherogenesis.
T11 916-1062 Sentence denotes There are also higher plasma levels of EL in subjects with type 2 diabetes, who are especially susceptible to the development of vascular lesions.
T12 1063-1219 Sentence denotes Therefore the inhibition of EL could play an important role in HDL metabolism and could be a new therapeutic strategy for the prevention of atherosclerosis.