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PubMed:22610315 JSONTXT

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GlyCosmos6-Glycan-Motif-Image

Id Subject Object Predicate Lexical cue image
T1 426-440 Glycan_Motif denotes Le(x) to Le(x) https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G79535HZ
T2 426-431 Glycan_Motif denotes Le(x) https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G01187XC
T3 435-440 Glycan_Motif denotes Le(x) https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G01187XC
T4 566-569 Glycan_Motif denotes GM3 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G91237TK|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G56516VH
T6 580-583 Glycan_Motif denotes GM3 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G91237TK|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G56516VH
T8 911-914 Glycan_Motif denotes GM3 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G91237TK|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G56516VH
T10 1085-1088 Glycan_Motif denotes GM3 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G91237TK|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G56516VH
T12 1132-1135 Glycan_Motif denotes GM3 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G91237TK|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G56516VH
T14 1140-1143 Glycan_Motif denotes GM2 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G79389NT|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G61168WC

Glycosmos6-MAT

Id Subject Object Predicate Lexical cue
T1 482-489 http://purl.obolibrary.org/obo/MAT_0000226 denotes embryos

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-87 Sentence denotes Carbohydrate to carbohydrate interaction in development process and cancer progression.
TextSentencer_T2 88-203 Sentence denotes Two types of carbohydrate to carbohydrate interaction (CCI) have been known to be involved in biological processes.
TextSentencer_T3 204-394 Sentence denotes One is the CCI between molecules expressed on interfacing cell membranes of different cells to mediate cell to cell adhesion, and subsequently induce cell signaling, and is termed trans-CCI.
TextSentencer_T4 395-565 Sentence denotes It has been indicated that the Le(x) to Le(x) interaction at the morula stage in mouse embryos plays an important role in the compaction process in embryonic development.
TextSentencer_T5 566-744 Sentence denotes GM3 to Gg3 or GM3 to LacCer interaction has been suggested to be involved in adhesion of tumor cells to endothelial cells, which is considered a crucial step in tumor metastasis.
TextSentencer_T6 745-874 Sentence denotes The other is the CCI between molecules expressed within the same microdomain of the cell surface membrane, and is termed cis-CCI.
TextSentencer_T7 875-1108 Sentence denotes The interaction between ganglioside GM3, and multi (>3) GlcNAc termini of N-linked glycans of epidermal growth factor receptor (EGFR), has been indicated as the molecular mechanism for the inhibitory effect of GM3 on EGFR activation.
TextSentencer_T8 1109-1329 Sentence denotes Also, the complex with GM3 and GM2 has been shown to inhibit the activation of hepatocyte growth factor (HGF) receptor, cMet, through its association with tetraspanin CD82, and results in the inhibition of cell motility.
TextSentencer_T9 1330-1482 Sentence denotes Since CCI research is still limited, more examples of CCI in biological processes in development, and cancer progression will be revealed in the future.
T1 0-87 Sentence denotes Carbohydrate to carbohydrate interaction in development process and cancer progression.
T2 88-203 Sentence denotes Two types of carbohydrate to carbohydrate interaction (CCI) have been known to be involved in biological processes.
T3 204-394 Sentence denotes One is the CCI between molecules expressed on interfacing cell membranes of different cells to mediate cell to cell adhesion, and subsequently induce cell signaling, and is termed trans-CCI.
T4 395-565 Sentence denotes It has been indicated that the Le(x) to Le(x) interaction at the morula stage in mouse embryos plays an important role in the compaction process in embryonic development.
T5 566-744 Sentence denotes GM3 to Gg3 or GM3 to LacCer interaction has been suggested to be involved in adhesion of tumor cells to endothelial cells, which is considered a crucial step in tumor metastasis.
T6 745-874 Sentence denotes The other is the CCI between molecules expressed within the same microdomain of the cell surface membrane, and is termed cis-CCI.
T7 875-1108 Sentence denotes The interaction between ganglioside GM3, and multi (>3) GlcNAc termini of N-linked glycans of epidermal growth factor receptor (EGFR), has been indicated as the molecular mechanism for the inhibitory effect of GM3 on EGFR activation.
T8 1109-1329 Sentence denotes Also, the complex with GM3 and GM2 has been shown to inhibit the activation of hepatocyte growth factor (HGF) receptor, cMet, through its association with tetraspanin CD82, and results in the inhibition of cell motility.
T9 1330-1482 Sentence denotes Since CCI research is still limited, more examples of CCI in biological processes in development, and cancer progression will be revealed in the future.

GlyCosmos6-Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 426-440 https://glytoucan.org/Structures/Glycans/G79535HZ denotes Le(x) to Le(x)
T2 426-431 https://glytoucan.org/Structures/Glycans/G01187XC denotes Le(x)
T3 435-440 https://glytoucan.org/Structures/Glycans/G01187XC denotes Le(x)
T4 566-569 https://glytoucan.org/Structures/Glycans/G56516VH denotes GM3
T5 566-569 https://glytoucan.org/Structures/Glycans/G91237TK denotes GM3
T6 580-583 https://glytoucan.org/Structures/Glycans/G56516VH denotes GM3
T7 580-583 https://glytoucan.org/Structures/Glycans/G91237TK denotes GM3
T8 911-914 https://glytoucan.org/Structures/Glycans/G56516VH denotes GM3
T9 911-914 https://glytoucan.org/Structures/Glycans/G91237TK denotes GM3
T10 1085-1088 https://glytoucan.org/Structures/Glycans/G56516VH denotes GM3
T11 1085-1088 https://glytoucan.org/Structures/Glycans/G91237TK denotes GM3
T12 1132-1135 https://glytoucan.org/Structures/Glycans/G56516VH denotes GM3
T13 1132-1135 https://glytoucan.org/Structures/Glycans/G91237TK denotes GM3
T14 1140-1143 https://glytoucan.org/Structures/Glycans/G61168WC denotes GM2
T15 1140-1143 https://glytoucan.org/Structures/Glycans/G79389NT denotes GM2

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 655-660 HP_0002664 denotes tumor
T2 727-732 HP_0002664 denotes tumor
T3 1432-1438 HP_0002664 denotes cancer

Allie

Id Subject Object Predicate Lexical cue
SS1_22610315_1_0 101-141 expanded denotes carbohydrate to carbohydrate interaction
SS2_22610315_1_0 143-146 abbr denotes CCI
SS1_22610315_6_0 969-1001 expanded denotes epidermal growth factor receptor
SS2_22610315_6_0 1003-1007 abbr denotes EGFR
SS1_22610315_7_0 1188-1212 expanded denotes hepatocyte growth factor
SS2_22610315_7_0 1214-1217 abbr denotes HGF
AE1_22610315_1_0 SS1_22610315_1_0 SS2_22610315_1_0 abbreviatedTo carbohydrate to carbohydrate interaction,CCI
AE1_22610315_6_0 SS1_22610315_6_0 SS2_22610315_6_0 abbreviatedTo epidermal growth factor receptor,EGFR
AE1_22610315_7_0 SS1_22610315_7_0 SS2_22610315_7_0 abbreviatedTo hepatocyte growth factor,HGF

NGLY1-deficiency

Id Subject Object Predicate Lexical cue
PD-NGLY1-deficiency-B_T1 931-937 chem:24139 denotes GlcNAc

GlyCosmos15-Glycan

Id Subject Object Predicate Lexical cue image
T1 566-569 Glycan denotes GM3 https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK
T2 573-576 Glycan denotes Gg3 https://api.glycosmos.org/wurcs2image/latest/png/binary/G90562PB
T3 580-583 Glycan denotes GM3 https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK
T4 911-914 Glycan denotes GM3 https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK
T5 1085-1088 Glycan denotes GM3 https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK
T6 1132-1135 Glycan denotes GM3 https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK
T7 1140-1143 Glycan denotes GM2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G79389NT

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 482-489 Body_part denotes embryos http://purl.obolibrary.org/obo/MAT_0000226

HP-phenotype

Id Subject Object Predicate Lexical cue hp_id
T1 68-74 Phenotype denotes cancer HP:0002664
T2 655-660 Phenotype denotes tumor HP:0002664
T3 727-732 Phenotype denotes tumor HP:0002664
T4 1432-1438 Phenotype denotes cancer HP:0002664

mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 68-74 Disease denotes cancer http://purl.obolibrary.org/obo/MONDO_0004992
T2 655-660 Disease denotes tumor http://purl.obolibrary.org/obo/MONDO_0005070
T3 727-732 Disease denotes tumor http://purl.obolibrary.org/obo/MONDO_0005070
T4 1432-1438 Disease denotes cancer http://purl.obolibrary.org/obo/MONDO_0004992

Glycan-GlyCosmos

Id Subject Object Predicate Lexical cue image
T1 566-569 Glycan denotes GM3 https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK
T2 573-576 Glycan denotes Gg3 https://api.glycosmos.org/wurcs2image/latest/png/binary/G90562PB
T3 580-583 Glycan denotes GM3 https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK
T4 911-914 Glycan denotes GM3 https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK
T5 1085-1088 Glycan denotes GM3 https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK
T6 1132-1135 Glycan denotes GM3 https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK
T7 1140-1143 Glycan denotes GM2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G79389NT

GlyCosmos15-HP

Id Subject Object Predicate Lexical cue hp_id
T1 68-74 Phenotype denotes cancer HP:0002664
T2 655-660 Phenotype denotes tumor HP:0002664
T3 727-732 Phenotype denotes tumor HP:0002664
T4 1432-1438 Phenotype denotes cancer HP:0002664

GlyCosmos15-CL

Id Subject Object Predicate Lexical cue cl_id
T1 655-666 Cell denotes tumor cells http://purl.obolibrary.org/obo/CL:0001063
T2 670-687 Cell denotes endothelial cells http://purl.obolibrary.org/obo/CL:0000115
T3 1188-1198 Cell denotes hepatocyte http://purl.obolibrary.org/obo/CL:0000182

GlyCosmos15-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 68-74 Disease denotes cancer MONDO:0004992
T2 655-660 Disease denotes tumor MONDO:0005070
T3 727-732 Disease denotes tumor MONDO:0005070
T4 1432-1438 Disease denotes cancer MONDO:0004992

GlyCosmos15-Taxon

Id Subject Object Predicate Lexical cue db_id
T1 460-466 Organism denotes morula 508940
T2 476-481 Organism denotes mouse 10088|10090

GlyCosmos15-Sentences

Id Subject Object Predicate Lexical cue
T1 0-87 Sentence denotes Carbohydrate to carbohydrate interaction in development process and cancer progression.
T2 88-203 Sentence denotes Two types of carbohydrate to carbohydrate interaction (CCI) have been known to be involved in biological processes.
T3 204-394 Sentence denotes One is the CCI between molecules expressed on interfacing cell membranes of different cells to mediate cell to cell adhesion, and subsequently induce cell signaling, and is termed trans-CCI.
T4 395-565 Sentence denotes It has been indicated that the Le(x) to Le(x) interaction at the morula stage in mouse embryos plays an important role in the compaction process in embryonic development.
T5 566-744 Sentence denotes GM3 to Gg3 or GM3 to LacCer interaction has been suggested to be involved in adhesion of tumor cells to endothelial cells, which is considered a crucial step in tumor metastasis.
T6 745-874 Sentence denotes The other is the CCI between molecules expressed within the same microdomain of the cell surface membrane, and is termed cis-CCI.
T7 875-1108 Sentence denotes The interaction between ganglioside GM3, and multi (>3) GlcNAc termini of N-linked glycans of epidermal growth factor receptor (EGFR), has been indicated as the molecular mechanism for the inhibitory effect of GM3 on EGFR activation.
T8 1109-1329 Sentence denotes Also, the complex with GM3 and GM2 has been shown to inhibit the activation of hepatocyte growth factor (HGF) receptor, cMet, through its association with tetraspanin CD82, and results in the inhibition of cell motility.
T9 1330-1482 Sentence denotes Since CCI research is still limited, more examples of CCI in biological processes in development, and cancer progression will be revealed in the future.

GlyCosmos15-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 262-276 Body_part denotes cell membranes http://purl.obolibrary.org/obo/GO_0005886
T2 460-466 Body_part denotes morula http://purl.obolibrary.org/obo/UBERON_0000085
T3 670-687 Body_part denotes endothelial cells http://purl.obolibrary.org/obo/CL_0000115
T4 842-850 Body_part denotes membrane http://purl.obolibrary.org/obo/UBERON_0000094
T5 969-985 Body_part denotes epidermal growth http://purl.obolibrary.org/obo/UBERON_0000021
T6 1188-1198 Body_part denotes hepatocyte http://purl.obolibrary.org/obo/CL_0000182

GlyCosmos15-FMA

Id Subject Object Predicate Lexical cue db_id
T1 262-276 Body_part denotes cell membranes FMA:63841
T2 460-466 Body_part denotes morula FMA:292334
T3 482-489 Body_part denotes embryos FMA:296970
T4 670-687 Body_part denotes endothelial cells FMA:66772
T5 829-841 Body_part denotes cell surface FMA:67653
T6 1188-1198 Body_part denotes hepatocyte FMA:14515

GlyCosmos15-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 482-489 Body_part denotes embryos http://purl.obolibrary.org/obo/MAT_0000226

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 460-466 OrganismTaxon denotes morula 508940
T2 476-481 OrganismTaxon denotes mouse 10088|10090

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 262-276 Body_part denotes cell membranes http://purl.obolibrary.org/obo/GO_0005886
T2 460-466 Body_part denotes morula http://purl.obolibrary.org/obo/UBERON_0000085
T3 670-687 Body_part denotes endothelial cells http://purl.obolibrary.org/obo/CL_0000115
T4 842-850 Body_part denotes membrane http://purl.obolibrary.org/obo/GO_0016020|http://purl.obolibrary.org/obo/UBERON_0000094|http://purl.obolibrary.org/obo/UBERON_0000158
T7 969-985 Body_part denotes epidermal growth http://purl.obolibrary.org/obo/UBERON_0000021
T8 1188-1198 Body_part denotes hepatocyte http://purl.obolibrary.org/obo/CL_0000182

CL-cell

Id Subject Object Predicate Lexical cue cl_id
T1 655-666 Cell denotes tumor cells http://purl.obolibrary.org/obo/CL:0001063
T2 670-687 Cell denotes endothelial cells http://purl.obolibrary.org/obo/CL:0000115
T3 1188-1198 Cell denotes hepatocyte http://purl.obolibrary.org/obo/CL:0000182