PubMed:22574726
Annnotations
Inflammaging
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-175 | Sentence | denotes | Quantitative metabolomic profiling of serum, plasma, and urine by (1)H NMR spectroscopy discriminates between patients with inflammatory bowel disease and healthy individuals. |
T2 | 176-280 | Sentence | denotes | Serologic biomarkers for inflammatory bowel disease (IBD) have yielded variable differentiating ability. |
T3 | 281-383 | Sentence | denotes | Quantitative analysis of a large number of metabolites is a promising method to detect IBD biomarkers. |
T4 | 384-537 | Sentence | denotes | Human subjects with active Crohn's disease (CD) and active ulcerative colitis (UC) were identified, and serum, plasma, and urine specimens were obtained. |
T5 | 538-762 | Sentence | denotes | We characterized 44 serum, 37 plasma, and 71 urine metabolites by use of (1)H NMR spectroscopy and "targeted analysis" to differentiate between diseased and non-diseased individuals, as well as between the CD and UC cohorts. |
T6 | 763-951 | Sentence | denotes | We used multiblock principal component analysis and hierarchical OPLS-DA for comparing several blocks derived from the same "objects" (e.g., subject) to examine differences in metabolites. |
T7 | 952-1222 | Sentence | denotes | In serum and plasma of IBD patients, methanol, mannose, formate, 3-methyl-2-oxovalerate, and amino acids such as isoleucine were the metabolites most prominently increased, whereas in urine, maximal increases were observed for mannitol, allantoin, xylose, and carnitine. |
T8 | 1223-1400 | Sentence | denotes | Both serum and plasma of UC and CD patients showed significant decreases in urea and citrate, whereas in urine, decreases were observed, among others, for betaine and hippurate. |
T9 | 1401-1511 | Sentence | denotes | Quantitative metabolomic profiling of serum, plasma, and urine discriminates between healthy and IBD subjects. |
T10 | 1512-1619 | Sentence | denotes | However, our results show that the metabolic differences between the CD and UC cohorts are less pronounced. |
T1 | 0-175 | Sentence | denotes | Quantitative metabolomic profiling of serum, plasma, and urine by (1)H NMR spectroscopy discriminates between patients with inflammatory bowel disease and healthy individuals. |
T2 | 176-280 | Sentence | denotes | Serologic biomarkers for inflammatory bowel disease (IBD) have yielded variable differentiating ability. |
T3 | 281-383 | Sentence | denotes | Quantitative analysis of a large number of metabolites is a promising method to detect IBD biomarkers. |
T4 | 384-537 | Sentence | denotes | Human subjects with active Crohn's disease (CD) and active ulcerative colitis (UC) were identified, and serum, plasma, and urine specimens were obtained. |
T5 | 538-762 | Sentence | denotes | We characterized 44 serum, 37 plasma, and 71 urine metabolites by use of (1)H NMR spectroscopy and "targeted analysis" to differentiate between diseased and non-diseased individuals, as well as between the CD and UC cohorts. |
T6 | 763-951 | Sentence | denotes | We used multiblock principal component analysis and hierarchical OPLS-DA for comparing several blocks derived from the same "objects" (e.g., subject) to examine differences in metabolites. |
T7 | 952-1222 | Sentence | denotes | In serum and plasma of IBD patients, methanol, mannose, formate, 3-methyl-2-oxovalerate, and amino acids such as isoleucine were the metabolites most prominently increased, whereas in urine, maximal increases were observed for mannitol, allantoin, xylose, and carnitine. |
T8 | 1223-1400 | Sentence | denotes | Both serum and plasma of UC and CD patients showed significant decreases in urea and citrate, whereas in urine, decreases were observed, among others, for betaine and hippurate. |
T9 | 1401-1511 | Sentence | denotes | Quantitative metabolomic profiling of serum, plasma, and urine discriminates between healthy and IBD subjects. |
T10 | 1512-1619 | Sentence | denotes | However, our results show that the metabolic differences between the CD and UC cohorts are less pronounced. |
GlyCosmos6-Glycan-Motif-Image
Id | Subject | Object | Predicate | Lexical cue | image |
---|---|---|---|---|---|
T1 | 999-1006 | Glycan_Motif | denotes | mannose | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G70323CJ |
sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-175 | Sentence | denotes | Quantitative metabolomic profiling of serum, plasma, and urine by (1)H NMR spectroscopy discriminates between patients with inflammatory bowel disease and healthy individuals. |
T2 | 176-280 | Sentence | denotes | Serologic biomarkers for inflammatory bowel disease (IBD) have yielded variable differentiating ability. |
T3 | 281-383 | Sentence | denotes | Quantitative analysis of a large number of metabolites is a promising method to detect IBD biomarkers. |
T4 | 384-537 | Sentence | denotes | Human subjects with active Crohn's disease (CD) and active ulcerative colitis (UC) were identified, and serum, plasma, and urine specimens were obtained. |
T5 | 538-762 | Sentence | denotes | We characterized 44 serum, 37 plasma, and 71 urine metabolites by use of (1)H NMR spectroscopy and "targeted analysis" to differentiate between diseased and non-diseased individuals, as well as between the CD and UC cohorts. |
T6 | 763-951 | Sentence | denotes | We used multiblock principal component analysis and hierarchical OPLS-DA for comparing several blocks derived from the same "objects" (e.g., subject) to examine differences in metabolites. |
T7 | 952-1222 | Sentence | denotes | In serum and plasma of IBD patients, methanol, mannose, formate, 3-methyl-2-oxovalerate, and amino acids such as isoleucine were the metabolites most prominently increased, whereas in urine, maximal increases were observed for mannitol, allantoin, xylose, and carnitine. |
T8 | 1223-1400 | Sentence | denotes | Both serum and plasma of UC and CD patients showed significant decreases in urea and citrate, whereas in urine, decreases were observed, among others, for betaine and hippurate. |
T9 | 1401-1511 | Sentence | denotes | Quantitative metabolomic profiling of serum, plasma, and urine discriminates between healthy and IBD subjects. |
T10 | 1512-1619 | Sentence | denotes | However, our results show that the metabolic differences between the CD and UC cohorts are less pronounced. |
T1 | 0-175 | Sentence | denotes | Quantitative metabolomic profiling of serum, plasma, and urine by (1)H NMR spectroscopy discriminates between patients with inflammatory bowel disease and healthy individuals. |
T2 | 176-280 | Sentence | denotes | Serologic biomarkers for inflammatory bowel disease (IBD) have yielded variable differentiating ability. |
T3 | 281-383 | Sentence | denotes | Quantitative analysis of a large number of metabolites is a promising method to detect IBD biomarkers. |
T4 | 384-537 | Sentence | denotes | Human subjects with active Crohn's disease (CD) and active ulcerative colitis (UC) were identified, and serum, plasma, and urine specimens were obtained. |
T5 | 538-762 | Sentence | denotes | We characterized 44 serum, 37 plasma, and 71 urine metabolites by use of (1)H NMR spectroscopy and "targeted analysis" to differentiate between diseased and non-diseased individuals, as well as between the CD and UC cohorts. |
T6 | 763-951 | Sentence | denotes | We used multiblock principal component analysis and hierarchical OPLS-DA for comparing several blocks derived from the same "objects" (e.g., subject) to examine differences in metabolites. |
T7 | 952-1222 | Sentence | denotes | In serum and plasma of IBD patients, methanol, mannose, formate, 3-methyl-2-oxovalerate, and amino acids such as isoleucine were the metabolites most prominently increased, whereas in urine, maximal increases were observed for mannitol, allantoin, xylose, and carnitine. |
T8 | 1223-1400 | Sentence | denotes | Both serum and plasma of UC and CD patients showed significant decreases in urea and citrate, whereas in urine, decreases were observed, among others, for betaine and hippurate. |
T9 | 1401-1511 | Sentence | denotes | Quantitative metabolomic profiling of serum, plasma, and urine discriminates between healthy and IBD subjects. |
T10 | 1512-1619 | Sentence | denotes | However, our results show that the metabolic differences between the CD and UC cohorts are less pronounced. |
GlyCosmos6-Glycan-Motif-Structure
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 999-1006 | https://glytoucan.org/Structures/Glycans/G70323CJ | denotes | mannose |
Glycosmos6-MAT
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 57-62 | http://purl.obolibrary.org/obo/MAT_0000058 | denotes | urine |
T2 | 507-512 | http://purl.obolibrary.org/obo/MAT_0000058 | denotes | urine |
T3 | 583-588 | http://purl.obolibrary.org/obo/MAT_0000058 | denotes | urine |
T4 | 1136-1141 | http://purl.obolibrary.org/obo/MAT_0000058 | denotes | urine |
T5 | 1328-1333 | http://purl.obolibrary.org/obo/MAT_0000058 | denotes | urine |
T6 | 1458-1463 | http://purl.obolibrary.org/obo/MAT_0000058 | denotes | urine |
PubmedHPO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 411-426 | HP_0100280 | denotes | Crohn's disease |
Allie
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
SS1_22574726_1_0 | 201-227 | expanded | denotes | inflammatory bowel disease |
SS2_22574726_1_0 | 229-232 | abbr | denotes | IBD |
SS1_22574726_3_0 | 411-426 | expanded | denotes | Crohn's disease |
SS2_22574726_3_0 | 428-430 | abbr | denotes | CD |
SS1_22574726_3_1 | 443-461 | expanded | denotes | ulcerative colitis |
SS2_22574726_3_1 | 463-465 | abbr | denotes | UC |
AE1_22574726_1_0 | SS1_22574726_1_0 | SS2_22574726_1_0 | abbreviatedTo | inflammatory bowel disease,IBD |
AE1_22574726_3_0 | SS1_22574726_3_0 | SS2_22574726_3_0 | abbreviatedTo | Crohn's disease,CD |
AE1_22574726_3_1 | SS1_22574726_3_1 | SS2_22574726_3_1 | abbreviatedTo | ulcerative colitis,UC |
Anatomy-MAT
Id | Subject | Object | Predicate | Lexical cue | mat_id |
---|---|---|---|---|---|
T1 | 57-62 | Body_part | denotes | urine | http://purl.obolibrary.org/obo/MAT_0000058 |
T2 | 507-512 | Body_part | denotes | urine | http://purl.obolibrary.org/obo/MAT_0000058 |
T3 | 583-588 | Body_part | denotes | urine | http://purl.obolibrary.org/obo/MAT_0000058 |
T4 | 1136-1141 | Body_part | denotes | urine | http://purl.obolibrary.org/obo/MAT_0000058 |
T5 | 1328-1333 | Body_part | denotes | urine | http://purl.obolibrary.org/obo/MAT_0000058 |
T6 | 1458-1463 | Body_part | denotes | urine | http://purl.obolibrary.org/obo/MAT_0000058 |
HP-phenotype
Id | Subject | Object | Predicate | Lexical cue | hp_id |
---|---|---|---|---|---|
T1 | 124-150 | Phenotype | denotes | inflammatory bowel disease | HP:0002037 |
T2 | 201-227 | Phenotype | denotes | inflammatory bowel disease | HP:0002037 |
T3 | 229-232 | Phenotype | denotes | IBD | HP:0002037 |
T4 | 368-371 | Phenotype | denotes | IBD | HP:0002037 |
T5 | 411-426 | Phenotype | denotes | Crohn's disease | HP:0100280 |
T6 | 428-430 | Phenotype | denotes | CD | HP:0100280 |
T7 | 443-461 | Phenotype | denotes | ulcerative colitis | HP:0100279 |
T8 | 463-465 | Phenotype | denotes | UC | HP:0100279 |
T9 | 744-746 | Phenotype | denotes | CD | HP:0100280 |
T10 | 751-753 | Phenotype | denotes | UC | HP:0100279 |
T11 | 975-978 | Phenotype | denotes | IBD | HP:0002037 |
T12 | 1248-1250 | Phenotype | denotes | UC | HP:0100279 |
T13 | 1255-1257 | Phenotype | denotes | CD | HP:0100280 |
T14 | 1498-1501 | Phenotype | denotes | IBD | HP:0002037 |
T15 | 1581-1583 | Phenotype | denotes | CD | HP:0100280 |
T16 | 1588-1590 | Phenotype | denotes | UC | HP:0100279 |
mondo_disease
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T1 | 124-150 | Disease | denotes | inflammatory bowel disease | http://purl.obolibrary.org/obo/MONDO_0005265 |
T2 | 201-227 | Disease | denotes | inflammatory bowel disease | http://purl.obolibrary.org/obo/MONDO_0005265 |
T3 | 229-232 | Disease | denotes | IBD | http://purl.obolibrary.org/obo/MONDO_0005052|http://purl.obolibrary.org/obo/MONDO_0005265 |
T5 | 368-371 | Disease | denotes | IBD | http://purl.obolibrary.org/obo/MONDO_0005052|http://purl.obolibrary.org/obo/MONDO_0005265 |
T7 | 411-426 | Disease | denotes | Crohn's disease | http://purl.obolibrary.org/obo/MONDO_0005011 |
T8 | 428-430 | Disease | denotes | CD | http://purl.obolibrary.org/obo/MONDO_0005011 |
T9 | 443-461 | Disease | denotes | ulcerative colitis | http://purl.obolibrary.org/obo/MONDO_0005101|http://purl.obolibrary.org/obo/MONDO_0009960 |
T11 | 463-465 | Disease | denotes | UC | http://purl.obolibrary.org/obo/MONDO_0005101 |
T12 | 744-746 | Disease | denotes | CD | http://purl.obolibrary.org/obo/MONDO_0005011 |
T13 | 751-753 | Disease | denotes | UC | http://purl.obolibrary.org/obo/MONDO_0005101 |
T14 | 975-978 | Disease | denotes | IBD | http://purl.obolibrary.org/obo/MONDO_0005052|http://purl.obolibrary.org/obo/MONDO_0005265 |
T16 | 1248-1250 | Disease | denotes | UC | http://purl.obolibrary.org/obo/MONDO_0005101 |
T17 | 1255-1257 | Disease | denotes | CD | http://purl.obolibrary.org/obo/MONDO_0005011 |
T18 | 1498-1501 | Disease | denotes | IBD | http://purl.obolibrary.org/obo/MONDO_0005052|http://purl.obolibrary.org/obo/MONDO_0005265 |
T20 | 1581-1583 | Disease | denotes | CD | http://purl.obolibrary.org/obo/MONDO_0005011 |
T21 | 1588-1590 | Disease | denotes | UC | http://purl.obolibrary.org/obo/MONDO_0005101 |
NCBITAXON
Id | Subject | Object | Predicate | Lexical cue | db_id |
---|---|---|---|---|---|
T1 | 384-389 | OrganismTaxon | denotes | Human | 9606 |
Anatomy-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T1 | 45-51 | Body_part | denotes | plasma | http://purl.obolibrary.org/obo/UBERON_0001969 |
T2 | 57-62 | Body_part | denotes | urine | http://purl.obolibrary.org/obo/UBERON_0001088 |
T3 | 137-142 | Body_part | denotes | bowel | http://purl.obolibrary.org/obo/UBERON_0000160 |
T4 | 214-219 | Body_part | denotes | bowel | http://purl.obolibrary.org/obo/UBERON_0000160 |
T5 | 495-501 | Body_part | denotes | plasma | http://purl.obolibrary.org/obo/UBERON_0001969 |
T6 | 507-512 | Body_part | denotes | urine | http://purl.obolibrary.org/obo/UBERON_0001088 |
T7 | 568-574 | Body_part | denotes | plasma | http://purl.obolibrary.org/obo/UBERON_0001969 |
T8 | 583-588 | Body_part | denotes | urine | http://purl.obolibrary.org/obo/UBERON_0001088 |
T9 | 965-971 | Body_part | denotes | plasma | http://purl.obolibrary.org/obo/UBERON_0001969 |
T10 | 1136-1141 | Body_part | denotes | urine | http://purl.obolibrary.org/obo/UBERON_0001088 |
T11 | 1238-1244 | Body_part | denotes | plasma | http://purl.obolibrary.org/obo/UBERON_0001969 |
T12 | 1328-1333 | Body_part | denotes | urine | http://purl.obolibrary.org/obo/UBERON_0001088 |
T13 | 1446-1452 | Body_part | denotes | plasma | http://purl.obolibrary.org/obo/UBERON_0001969 |
T14 | 1458-1463 | Body_part | denotes | urine | http://purl.obolibrary.org/obo/UBERON_0001088 |