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PubMed:22534567 JSONTXT

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Glycan-Motif

Id Subject Object Predicate Lexical cue
T1 51-58 https://glytoucan.org/Structures/Glycans/G70323CJ denotes mannose
T2 148-155 https://glytoucan.org/Structures/Glycans/G70323CJ denotes Mannose

GlyCosmos6-Glycan-Motif-Image

Id Subject Object Predicate Lexical cue image
T1 51-58 Glycan_Motif denotes mannose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G70323CJ
T2 148-155 Glycan_Motif denotes Mannose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G70323CJ

GlyCosmos6-Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 51-58 https://glytoucan.org/Structures/Glycans/G70323CJ denotes mannose
T2 148-155 https://glytoucan.org/Structures/Glycans/G70323CJ denotes Mannose

ICD10

Id Subject Object Predicate Lexical cue
T1 38-50 http://purl.bioontology.org/ontology/ICD10/A15-A19.9 denotes tuberculosis
T2 254-266 http://purl.bioontology.org/ontology/ICD10/A15-A19.9 denotes tuberculosis
T3 433-445 http://purl.bioontology.org/ontology/ICD10/A15-A19.9 denotes tuberculosis
T4 1147-1159 http://purl.bioontology.org/ontology/ICD10/A15-A19.9 denotes tuberculosis

GlycoBiology-FMA

Id Subject Object Predicate Lexical cue
_T1 51-58 FMAID:196796 denotes mannose
_T2 51-58 FMAID:82801 denotes mannose
_T3 141-146 FMAID:68646 denotes cells
_T4 141-146 FMAID:169002 denotes cells
_T5 148-155 FMAID:82801 denotes Mannose
_T6 148-155 FMAID:196796 denotes Mannose
_T7 545-550 FMAID:169002 denotes cells
_T8 545-550 FMAID:68646 denotes cells
_T9 748-759 FMAID:82738 denotes fatty acids
_T10 748-759 FMAID:196726 denotes fatty acids
_T11 1469-1482 FMAID:50603 denotes Compositional
_T12 1469-1482 FMAID:146309 denotes Compositional
_T13 1639-1644 FMAID:169002 denotes cells
_T14 1639-1644 FMAID:68646 denotes cells
_T15 1657-1668 FMAID:183399 denotes compartment
_T16 1657-1668 FMAID:76700 denotes compartment
_T17 1657-1668 FMAID:183854 denotes compartment

uniprot-human

Id Subject Object Predicate Lexical cue
T1 123-127 http://www.uniprot.org/uniprot/P29016 denotes CD1b
T2 527-531 http://www.uniprot.org/uniprot/P29016 denotes CD1b
T3 955-959 http://www.uniprot.org/uniprot/P29016 denotes CD1b
T4 1049-1053 http://www.uniprot.org/uniprot/P29016 denotes CD1b
T5 1439-1443 http://www.uniprot.org/uniprot/P29016 denotes CD1b
T6 1413-1425 http://www.uniprot.org/uniprot/P01579 denotes interferon-γ

uniprot-mouse

Id Subject Object Predicate Lexical cue
T1 1413-1425 http://www.uniprot.org/uniprot/P01580 denotes interferon-γ

GlycoBiology-NCBITAXON

Id Subject Object Predicate Lexical cue
T1 24-37 http://purl.bioontology.org/ontology/NCBITAXON/46351 denotes Mycobacterium
T2 24-37 http://purl.bioontology.org/ontology/NCBITAXON/1766 denotes Mycobacterium
T3 24-37 http://purl.bioontology.org/ontology/NCBITAXON/28045 denotes Mycobacterium
T4 24-37 http://purl.bioontology.org/ontology/NCBITAXON/98668 denotes Mycobacterium
T5 24-37 http://purl.bioontology.org/ontology/NCBITAXON/370526 denotes Mycobacterium
T6 24-37 http://purl.bioontology.org/ontology/NCBITAXON/318424 denotes Mycobacterium
T7 24-37 http://purl.bioontology.org/ontology/NCBITAXON/33894 denotes Mycobacterium
T8 24-37 http://purl.bioontology.org/ontology/NCBITAXON/39693 denotes Mycobacterium
T9 24-37 http://purl.bioontology.org/ontology/NCBITAXON/230710 denotes Mycobacterium
T10 24-37 http://purl.bioontology.org/ontology/NCBITAXON/368455 denotes Mycobacterium
T11 24-37 http://purl.bioontology.org/ontology/NCBITAXON/1288388 denotes Mycobacterium
T12 24-37 http://purl.bioontology.org/ontology/NCBITAXON/1794 denotes Mycobacterium
T13 24-37 http://purl.bioontology.org/ontology/NCBITAXON/470074 denotes Mycobacterium
T14 24-37 http://purl.bioontology.org/ontology/NCBITAXON/1795 denotes Mycobacterium
T15 24-37 http://purl.bioontology.org/ontology/NCBITAXON/1790 denotes Mycobacterium
T16 24-37 http://purl.bioontology.org/ontology/NCBITAXON/1781 denotes Mycobacterium
T17 24-37 http://purl.bioontology.org/ontology/NCBITAXON/1791 denotes Mycobacterium
T18 24-37 http://purl.bioontology.org/ontology/NCBITAXON/912594 denotes Mycobacterium
T19 24-37 http://purl.bioontology.org/ontology/NCBITAXON/56425 denotes Mycobacterium
T20 24-37 http://purl.bioontology.org/ontology/NCBITAXON/319706 denotes Mycobacterium
T21 24-50 http://purl.bioontology.org/ontology/NCBITAXON/77643 denotes Mycobacterium tuberculosis
T22 38-50 http://purl.bioontology.org/ontology/NCBITAXON/1407443 denotes tuberculosis
T23 141-146 http://purl.bioontology.org/ontology/STY/T025 denotes cells
T24 240-253 http://purl.bioontology.org/ontology/NCBITAXON/1766 denotes Mycobacterium
T25 240-253 http://purl.bioontology.org/ontology/NCBITAXON/56425 denotes Mycobacterium
T26 240-253 http://purl.bioontology.org/ontology/NCBITAXON/1794 denotes Mycobacterium
T27 240-253 http://purl.bioontology.org/ontology/NCBITAXON/28045 denotes Mycobacterium
T28 240-253 http://purl.bioontology.org/ontology/NCBITAXON/46351 denotes Mycobacterium
T29 240-253 http://purl.bioontology.org/ontology/NCBITAXON/1791 denotes Mycobacterium
T30 240-253 http://purl.bioontology.org/ontology/NCBITAXON/912594 denotes Mycobacterium
T31 240-253 http://purl.bioontology.org/ontology/NCBITAXON/1790 denotes Mycobacterium
T32 240-253 http://purl.bioontology.org/ontology/NCBITAXON/1781 denotes Mycobacterium
T33 240-253 http://purl.bioontology.org/ontology/NCBITAXON/470074 denotes Mycobacterium
T34 240-253 http://purl.bioontology.org/ontology/NCBITAXON/1795 denotes Mycobacterium
T35 240-253 http://purl.bioontology.org/ontology/NCBITAXON/1288388 denotes Mycobacterium
T36 240-253 http://purl.bioontology.org/ontology/NCBITAXON/319706 denotes Mycobacterium
T37 240-253 http://purl.bioontology.org/ontology/NCBITAXON/230710 denotes Mycobacterium
T38 240-253 http://purl.bioontology.org/ontology/NCBITAXON/370526 denotes Mycobacterium
T39 240-253 http://purl.bioontology.org/ontology/NCBITAXON/33894 denotes Mycobacterium
T40 240-253 http://purl.bioontology.org/ontology/NCBITAXON/39693 denotes Mycobacterium
T41 240-253 http://purl.bioontology.org/ontology/NCBITAXON/98668 denotes Mycobacterium
T42 240-253 http://purl.bioontology.org/ontology/NCBITAXON/318424 denotes Mycobacterium
T43 240-253 http://purl.bioontology.org/ontology/NCBITAXON/368455 denotes Mycobacterium
T44 240-266 http://purl.bioontology.org/ontology/NCBITAXON/77643 denotes Mycobacterium tuberculosis
T45 254-266 http://purl.bioontology.org/ontology/NCBITAXON/1407443 denotes tuberculosis
T46 282-286 http://purl.bioontology.org/ontology/NCBITAXON/9973 denotes Many
T47 433-445 http://purl.bioontology.org/ontology/NCBITAXON/1407443 denotes tuberculosis
T48 545-550 http://purl.bioontology.org/ontology/STY/T025 denotes cells
T49 609-622 http://purl.bioontology.org/ontology/NCBITAXON/691256 denotes heterogeneous
T50 609-622 http://purl.bioontology.org/ontology/NCBITAXON/1113441 denotes heterogeneous
T51 1147-1159 http://purl.bioontology.org/ontology/NCBITAXON/1407443 denotes tuberculosis
T52 1639-1644 http://purl.bioontology.org/ontology/STY/T025 denotes cells

GO-BP

Id Subject Object Predicate Lexical cue
T1 353-378 http://purl.obolibrary.org/obo/GO_0051701 denotes interacting with the host
T2 472-497 http://purl.obolibrary.org/obo/GO_0002821 denotes adaptive immune responses
T3 472-497 http://purl.obolibrary.org/obo/GO_0002820 denotes adaptive immune responses
T4 472-497 http://purl.obolibrary.org/obo/GO_0002250 denotes adaptive immune responses
T5 472-497 http://purl.obolibrary.org/obo/GO_0002819 denotes adaptive immune responses
T6 481-497 http://purl.obolibrary.org/obo/GO_0006955 denotes immune responses
T7 1124-1140 http://purl.obolibrary.org/obo/GO_0006955 denotes immune responses
T8 773-781 http://purl.obolibrary.org/obo/GO_0007595 denotes lactates
T9 1067-1083 http://purl.obolibrary.org/obo/GO_0008037 denotes cell recognition
T10 1114-1140 http://purl.obolibrary.org/obo/GO_0002443 denotes mediating immune responses
T11 1114-1140 http://purl.obolibrary.org/obo/GO_0016064 denotes mediating immune responses
T12 1383-1423 http://purl.obolibrary.org/obo/GO_0032727 denotes stimulating the production of interferon
T13 1383-1423 http://purl.obolibrary.org/obo/GO_0032728 denotes stimulating the production of interferon
T14 1383-1423 http://purl.obolibrary.org/obo/GO_0032729 denotes stimulating the production of interferon
T15 1399-1423 http://purl.obolibrary.org/obo/GO_0001816 denotes production of interferon

GO-CC

Id Subject Object Predicate Lexical cue
T1 141-146 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T2 545-550 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T3 267-271 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T4 970-974 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T5 1067-1071 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T6 1457-1461 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T7 267-280 http://purl.obolibrary.org/obo/GO_0030313 denotes cell envelope
T8 272-280 http://purl.obolibrary.org/obo/GO_0009274 denotes envelope
T9 374-378 http://purl.obolibrary.org/obo/GO_0018995 denotes host
T10 404-417 http://purl.obolibrary.org/obo/GO_0005622 denotes intracellular

Allie

Id Subject Object Predicate Lexical cue
SS1_22534567_1_0 148-180 expanded denotes Mannose-capped lipoarabinomannan
SS2_22534567_1_0 182-188 abbr denotes ManLAM
AE1_22534567_1_0 SS1_22534567_1_0 SS2_22534567_1_0 abbreviatedTo Mannose-capped lipoarabinomannan,ManLAM

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-147 Sentence denotes Isolation of a distinct Mycobacterium tuberculosis mannose-capped lipoarabinomannan isoform responsible for recognition by CD1b-restricted T cells.
TextSentencer_T2 148-281 Sentence denotes Mannose-capped lipoarabinomannan (ManLAM) is a complex lipoglycan abundantly present in the Mycobacterium tuberculosis cell envelope.
TextSentencer_T3 282-551 Sentence denotes Many biological properties have been ascribed to ManLAM, from directly interacting with the host and participating in the intracellular survival of M. tuberculosis, to triggering innate and adaptive immune responses, including the activation of CD1b-restricted T cells.
TextSentencer_T4 552-701 Sentence denotes Due to its structural complexity, ManLAM is considered a heterogeneous population of molecules which may explain its different biological properties.
TextSentencer_T5 702-986 Sentence denotes The presence of various modifications such as fatty acids, succinates, lactates, phosphoinositides and methylthioxylose in ManLAM have proven to correlate directly with its biological activity and may potentially be involved in the interactions between CD1b and the T cell population.
TextSentencer_T6 987-1287 Sentence denotes To further delineate the specific ManLAM epitopes involved in CD1b-restricted T cell recognition, and their potential roles in mediating immune responses in M. tuberculosis infection, we established a method to resolve ManLAM into eight different isoforms based on their different isoelectric values.
TextSentencer_T7 1288-1468 Sentence denotes Our results show that a ManLAM isoform with an isoelectric value of 5.8 was the most potent in stimulating the production of interferon-γ in different CD1b-restricted T-cell lines.
TextSentencer_T8 1469-1669 Sentence denotes Compositional analyses of these isoforms of ManLAM revealed a direct relationship between the overall charge of the ManLAM molecule and its capacity to be presented to T cells via the CD1 compartment.
T1 0-147 Sentence denotes Isolation of a distinct Mycobacterium tuberculosis mannose-capped lipoarabinomannan isoform responsible for recognition by CD1b-restricted T cells.
T2 148-281 Sentence denotes Mannose-capped lipoarabinomannan (ManLAM) is a complex lipoglycan abundantly present in the Mycobacterium tuberculosis cell envelope.
T3 282-551 Sentence denotes Many biological properties have been ascribed to ManLAM, from directly interacting with the host and participating in the intracellular survival of M. tuberculosis, to triggering innate and adaptive immune responses, including the activation of CD1b-restricted T cells.
T4 552-701 Sentence denotes Due to its structural complexity, ManLAM is considered a heterogeneous population of molecules which may explain its different biological properties.
T5 702-986 Sentence denotes The presence of various modifications such as fatty acids, succinates, lactates, phosphoinositides and methylthioxylose in ManLAM have proven to correlate directly with its biological activity and may potentially be involved in the interactions between CD1b and the T cell population.
T6 987-1287 Sentence denotes To further delineate the specific ManLAM epitopes involved in CD1b-restricted T cell recognition, and their potential roles in mediating immune responses in M. tuberculosis infection, we established a method to resolve ManLAM into eight different isoforms based on their different isoelectric values.
T7 1288-1468 Sentence denotes Our results show that a ManLAM isoform with an isoelectric value of 5.8 was the most potent in stimulating the production of interferon-γ in different CD1b-restricted T-cell lines.
T8 1469-1669 Sentence denotes Compositional analyses of these isoforms of ManLAM revealed a direct relationship between the overall charge of the ManLAM molecule and its capacity to be presented to T cells via the CD1 compartment.
T1 0-147 Sentence denotes Isolation of a distinct Mycobacterium tuberculosis mannose-capped lipoarabinomannan isoform responsible for recognition by CD1b-restricted T cells.
T2 148-281 Sentence denotes Mannose-capped lipoarabinomannan (ManLAM) is a complex lipoglycan abundantly present in the Mycobacterium tuberculosis cell envelope.
T3 282-551 Sentence denotes Many biological properties have been ascribed to ManLAM, from directly interacting with the host and participating in the intracellular survival of M. tuberculosis, to triggering innate and adaptive immune responses, including the activation of CD1b-restricted T cells.
T4 552-701 Sentence denotes Due to its structural complexity, ManLAM is considered a heterogeneous population of molecules which may explain its different biological properties.
T5 702-986 Sentence denotes The presence of various modifications such as fatty acids, succinates, lactates, phosphoinositides and methylthioxylose in ManLAM have proven to correlate directly with its biological activity and may potentially be involved in the interactions between CD1b and the T cell population.
T6 987-1287 Sentence denotes To further delineate the specific ManLAM epitopes involved in CD1b-restricted T cell recognition, and their potential roles in mediating immune responses in M. tuberculosis infection, we established a method to resolve ManLAM into eight different isoforms based on their different isoelectric values.
T7 1288-1468 Sentence denotes Our results show that a ManLAM isoform with an isoelectric value of 5.8 was the most potent in stimulating the production of interferon-γ in different CD1b-restricted T-cell lines.
T8 1469-1669 Sentence denotes Compositional analyses of these isoforms of ManLAM revealed a direct relationship between the overall charge of the ManLAM molecule and its capacity to be presented to T cells via the CD1 compartment.

mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 38-50 Disease denotes tuberculosis http://purl.obolibrary.org/obo/MONDO_0018076
T2 254-266 Disease denotes tuberculosis http://purl.obolibrary.org/obo/MONDO_0018076
T3 433-445 Disease denotes tuberculosis http://purl.obolibrary.org/obo/MONDO_0018076
T4 1147-1159 Disease denotes tuberculosis http://purl.obolibrary.org/obo/MONDO_0018076
T5 1160-1169 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 24-50 OrganismTaxon denotes Mycobacterium tuberculosis 1773
T2 240-266 OrganismTaxon denotes Mycobacterium tuberculosis 1773

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 272-280 Body_part denotes envelope http://purl.obolibrary.org/obo/GO_0031975
T2 404-417 Body_part denotes intracellular http://purl.obolibrary.org/obo/GO_0005622
T3 968-974 Body_part denotes T cell http://purl.obolibrary.org/obo/CL_0000084
T4 1065-1071 Body_part denotes T cell http://purl.obolibrary.org/obo/CL_0000084
T5 1455-1461 Body_part denotes T-cell http://purl.obolibrary.org/obo/CL_0000084

CL-cell

Id Subject Object Predicate Lexical cue cl_id
T1 139-146 Cell denotes T cells http://purl.obolibrary.org/obo/CL:0000084
T2 543-550 Cell denotes T cells http://purl.obolibrary.org/obo/CL:0000084
T3 968-974 Cell denotes T cell http://purl.obolibrary.org/obo/CL:0000084
T4 1065-1071 Cell denotes T cell http://purl.obolibrary.org/obo/CL:0000084
T5 1455-1461 Cell denotes T-cell http://purl.obolibrary.org/obo/CL:0000084
T6 1637-1644 Cell denotes T cells http://purl.obolibrary.org/obo/CL:0000084