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PubMed:2249984 JSONTXT

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GlyCosmos15-Species-PubTator

Id Subject Object Predicate Lexical cue db_id
3 46-49 Species denotes rat 10116
5 73-89 Species denotes Escherichia coli 562
44 197-200 Species denotes rat 10116
47 271-274 Species denotes rat 10116
49 295-301 Species denotes murine 10090
53 557-560 Species denotes rat 10116
56 636-652 Species denotes Escherichia coli 562
62 904-909 Species denotes mouse 10090
63 995-998 Species denotes rat 10116

GlyCosmos6-Glycan-Motif-Image

Id Subject Object Predicate Lexical cue image
T1 1105-1124 Glycan_Motif denotes N-acetyllactosamine https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00055MO
T2 1197-1206 Glycan_Motif denotes galactose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G68158BT|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G65889KE

sentences

Id Subject Object Predicate Lexical cue
T1 0-90 Sentence denotes Expression of biologically active recombinant rat IgE-binding protein in Escherichia coli.
T2 91-233 Sentence denotes IgE-binding protein (epsilon BP) is a protein which has affinity for IgE and was originally identified in rat basophilic leukemia (RBL) cells.
T3 234-335 Sentence denotes Subsequently, it was found to be the rat homolog of CBP35, a murine beta-galactoside-specific lectin.
T4 336-436 Sentence denotes This protein is also designated as L-34 and RL-29 and studied independently by several laboratories.
T5 437-550 Sentence denotes More recently, CBP35 (epsilon BP) was found to be equivalent to Mac-2, a surface marker on activated macrophages.
T6 551-653 Sentence denotes Using rat epsilon BP cDNA, we have succeeded in expressing recombinant epsilon BP in Escherichia coli.
T7 654-855 Sentence denotes Milligram quantities of homogeneous epsilon BP could be obtained from bacterial lysate in a one-step affinity purification procedure utilizing lactosyl-Sepharose 4B and elution with a lactose gradient.
T8 856-1010 Sentence denotes The recombinant epsilon BP (r epsilon BP) binds mouse IgE and retains reactivity to anti-peptide antibodies specific for a sequence within rat epsilon BP.
T9 1011-1315 Sentence denotes The purified r epsilon BP exhibits binding activity to various saccharides, with affinity for N-acetyllactosamine greater than thiodigalactoside greater than lactose much greater than D-galactose greater than L-arabinose, an order identical to that exhibited by native epsilon BP isolated from RBL cells.
T10 1316-1412 Sentence denotes The recombinant lectin displayed hemagglutination activity when tested with rabbit erythrocytes.
T11 1413-1654 Sentence denotes Although epsilon BP shares sequence homology to other lectins containing S-type (thiol-dependent) carbohydrate-recognition domains, r epsilon BP is resistant to air oxidation and does not require reducing agents for maintaining its activity.
T12 1655-1811 Sentence denotes Furthermore, the single cysteine residue appears to be unexposed and can be alkylated only when the protein is denatured in 5.6 M guanidinium hydrochloride.
T13 1812-1985 Sentence denotes The availability of a source for a large quantity of epsilon BP should facilitate the analysis of biological function(s) and structure-activity relationships of this lectin.
T1 0-90 Sentence denotes Expression of biologically active recombinant rat IgE-binding protein in Escherichia coli.
T2 91-233 Sentence denotes IgE-binding protein (epsilon BP) is a protein which has affinity for IgE and was originally identified in rat basophilic leukemia (RBL) cells.
T3 234-335 Sentence denotes Subsequently, it was found to be the rat homolog of CBP35, a murine beta-galactoside-specific lectin.
T4 336-436 Sentence denotes This protein is also designated as L-34 and RL-29 and studied independently by several laboratories.
T5 437-550 Sentence denotes More recently, CBP35 (epsilon BP) was found to be equivalent to Mac-2, a surface marker on activated macrophages.
T6 551-653 Sentence denotes Using rat epsilon BP cDNA, we have succeeded in expressing recombinant epsilon BP in Escherichia coli.
T7 654-855 Sentence denotes Milligram quantities of homogeneous epsilon BP could be obtained from bacterial lysate in a one-step affinity purification procedure utilizing lactosyl-Sepharose 4B and elution with a lactose gradient.
T8 856-1010 Sentence denotes The recombinant epsilon BP (r epsilon BP) binds mouse IgE and retains reactivity to anti-peptide antibodies specific for a sequence within rat epsilon BP.
T9 1011-1315 Sentence denotes The purified r epsilon BP exhibits binding activity to various saccharides, with affinity for N-acetyllactosamine greater than thiodigalactoside greater than lactose much greater than D-galactose greater than L-arabinose, an order identical to that exhibited by native epsilon BP isolated from RBL cells.
T10 1316-1412 Sentence denotes The recombinant lectin displayed hemagglutination activity when tested with rabbit erythrocytes.
T11 1413-1654 Sentence denotes Although epsilon BP shares sequence homology to other lectins containing S-type (thiol-dependent) carbohydrate-recognition domains, r epsilon BP is resistant to air oxidation and does not require reducing agents for maintaining its activity.
T12 1655-1811 Sentence denotes Furthermore, the single cysteine residue appears to be unexposed and can be alkylated only when the protein is denatured in 5.6 M guanidinium hydrochloride.
T13 1812-1985 Sentence denotes The availability of a source for a large quantity of epsilon BP should facilitate the analysis of biological function(s) and structure-activity relationships of this lectin.

GlyCosmos6-Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 1105-1124 https://glytoucan.org/Structures/Glycans/G00055MO denotes N-acetyllactosamine
T2 1197-1206 https://glytoucan.org/Structures/Glycans/G65889KE denotes galactose
T3 1197-1206 https://glytoucan.org/Structures/Glycans/G68158BT denotes galactose

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 212-220 HP_0001909 denotes leukemia
T2 1399-1411 HP_0001901 denotes erythrocytes

GlyCosmos15-Glycan

Id Subject Object Predicate Lexical cue image
T1 838-845 Glycan denotes lactose https://api.glycosmos.org/wurcs2image/latest/png/binary/G15541SE
T2 1169-1176 Glycan denotes lactose https://api.glycosmos.org/wurcs2image/latest/png/binary/G15541SE

mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 201-220 Disease denotes basophilic leukemia http://purl.obolibrary.org/obo/MONDO_0019458

HP-phenotype

Id Subject Object Predicate Lexical cue hp_id
T1 212-220 Phenotype denotes leukemia HP:0001909

Glycan-GlyCosmos

Id Subject Object Predicate Lexical cue image
T1 838-845 Glycan denotes lactose https://api.glycosmos.org/wurcs2image/latest/png/binary/G15541SE
T2 1169-1176 Glycan denotes lactose https://api.glycosmos.org/wurcs2image/latest/png/binary/G15541SE

GlyCosmos15-HP

Id Subject Object Predicate Lexical cue hp_id
T1 212-220 Phenotype denotes leukemia HP:0001909

GlyCosmos15-CL

Id Subject Object Predicate Lexical cue cl_id
T1 112-119 Cell denotes epsilon http://purl.obolibrary.org/obo/CL:0003025
T2 201-211 Cell denotes basophilic http://purl.obolibrary.org/obo/CL:0000767
T3 459-466 Cell denotes epsilon http://purl.obolibrary.org/obo/CL:0003025
T4 538-549 Cell denotes macrophages http://purl.obolibrary.org/obo/CL:0000235|http://purl.obolibrary.org/obo/CL:0000394
T6 561-568 Cell denotes epsilon http://purl.obolibrary.org/obo/CL:0003025
T7 622-629 Cell denotes epsilon http://purl.obolibrary.org/obo/CL:0003025
T8 690-697 Cell denotes epsilon http://purl.obolibrary.org/obo/CL:0003025
T9 872-879 Cell denotes epsilon http://purl.obolibrary.org/obo/CL:0003025
T10 886-893 Cell denotes epsilon http://purl.obolibrary.org/obo/CL:0003025
T11 999-1006 Cell denotes epsilon http://purl.obolibrary.org/obo/CL:0003025
T12 1026-1033 Cell denotes epsilon http://purl.obolibrary.org/obo/CL:0003025
T13 1280-1287 Cell denotes epsilon http://purl.obolibrary.org/obo/CL:0003025
T14 1399-1411 Cell denotes erythrocytes http://purl.obolibrary.org/obo/CL:0000232
T15 1422-1429 Cell denotes epsilon http://purl.obolibrary.org/obo/CL:0003025
T16 1547-1554 Cell denotes epsilon http://purl.obolibrary.org/obo/CL:0003025
T17 1865-1872 Cell denotes epsilon http://purl.obolibrary.org/obo/CL:0003025

GlyCosmos15-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 201-220 Disease denotes basophilic leukemia MONDO:0019458

GlyCosmos15-Sentences

Id Subject Object Predicate Lexical cue
T1 0-90 Sentence denotes Expression of biologically active recombinant rat IgE-binding protein in Escherichia coli.
T2 91-233 Sentence denotes IgE-binding protein (epsilon BP) is a protein which has affinity for IgE and was originally identified in rat basophilic leukemia (RBL) cells.
T3 234-335 Sentence denotes Subsequently, it was found to be the rat homolog of CBP35, a murine beta-galactoside-specific lectin.
T4 336-436 Sentence denotes This protein is also designated as L-34 and RL-29 and studied independently by several laboratories.
T5 437-550 Sentence denotes More recently, CBP35 (epsilon BP) was found to be equivalent to Mac-2, a surface marker on activated macrophages.
T6 551-653 Sentence denotes Using rat epsilon BP cDNA, we have succeeded in expressing recombinant epsilon BP in Escherichia coli.
T7 654-855 Sentence denotes Milligram quantities of homogeneous epsilon BP could be obtained from bacterial lysate in a one-step affinity purification procedure utilizing lactosyl-Sepharose 4B and elution with a lactose gradient.
T8 856-1010 Sentence denotes The recombinant epsilon BP (r epsilon BP) binds mouse IgE and retains reactivity to anti-peptide antibodies specific for a sequence within rat epsilon BP.
T9 1011-1315 Sentence denotes The purified r epsilon BP exhibits binding activity to various saccharides, with affinity for N-acetyllactosamine greater than thiodigalactoside greater than lactose much greater than D-galactose greater than L-arabinose, an order identical to that exhibited by native epsilon BP isolated from RBL cells.
T10 1316-1412 Sentence denotes The recombinant lectin displayed hemagglutination activity when tested with rabbit erythrocytes.
T11 1413-1654 Sentence denotes Although epsilon BP shares sequence homology to other lectins containing S-type (thiol-dependent) carbohydrate-recognition domains, r epsilon BP is resistant to air oxidation and does not require reducing agents for maintaining its activity.
T12 1655-1811 Sentence denotes Furthermore, the single cysteine residue appears to be unexposed and can be alkylated only when the protein is denatured in 5.6 M guanidinium hydrochloride.
T13 1812-1985 Sentence denotes The availability of a source for a large quantity of epsilon BP should facilitate the analysis of biological function(s) and structure-activity relationships of this lectin.

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 46-49 OrganismTaxon denotes rat 10114|10116
T3 73-89 OrganismTaxon denotes Escherichia coli 562
T4 197-200 OrganismTaxon denotes rat 10114|10116
T6 271-274 OrganismTaxon denotes rat 10114|10116
T8 557-560 OrganismTaxon denotes rat 10114|10116
T10 636-652 OrganismTaxon denotes Escherichia coli 562
T11 904-909 OrganismTaxon denotes mouse 10088|10090
T13 995-998 OrganismTaxon denotes rat 10114|10116

Lectin-Jamboree-Sentence

Id Subject Object Predicate Lexical cue
T1 0-90 Sentence denotes Expression of biologically active recombinant rat IgE-binding protein in Escherichia coli.
T2 91-233 Sentence denotes IgE-binding protein (epsilon BP) is a protein which has affinity for IgE and was originally identified in rat basophilic leukemia (RBL) cells.
T3 234-335 Sentence denotes Subsequently, it was found to be the rat homolog of CBP35, a murine beta-galactoside-specific lectin.
T4 336-436 Sentence denotes This protein is also designated as L-34 and RL-29 and studied independently by several laboratories.
T5 437-550 Sentence denotes More recently, CBP35 (epsilon BP) was found to be equivalent to Mac-2, a surface marker on activated macrophages.
T6 551-653 Sentence denotes Using rat epsilon BP cDNA, we have succeeded in expressing recombinant epsilon BP in Escherichia coli.
T7 654-855 Sentence denotes Milligram quantities of homogeneous epsilon BP could be obtained from bacterial lysate in a one-step affinity purification procedure utilizing lactosyl-Sepharose 4B and elution with a lactose gradient.
T8 856-1010 Sentence denotes The recombinant epsilon BP (r epsilon BP) binds mouse IgE and retains reactivity to anti-peptide antibodies specific for a sequence within rat epsilon BP.
T9 1011-1315 Sentence denotes The purified r epsilon BP exhibits binding activity to various saccharides, with affinity for N-acetyllactosamine greater than thiodigalactoside greater than lactose much greater than D-galactose greater than L-arabinose, an order identical to that exhibited by native epsilon BP isolated from RBL cells.
T10 1316-1412 Sentence denotes The recombinant lectin displayed hemagglutination activity when tested with rabbit erythrocytes.
T11 1413-1654 Sentence denotes Although epsilon BP shares sequence homology to other lectins containing S-type (thiol-dependent) carbohydrate-recognition domains, r epsilon BP is resistant to air oxidation and does not require reducing agents for maintaining its activity.
T12 1655-1811 Sentence denotes Furthermore, the single cysteine residue appears to be unexposed and can be alkylated only when the protein is denatured in 5.6 M guanidinium hydrochloride.
T13 1812-1985 Sentence denotes The availability of a source for a large quantity of epsilon BP should facilitate the analysis of biological function(s) and structure-activity relationships of this lectin.

GlyCosmos15-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 538-549 Body_part denotes macrophages http://purl.obolibrary.org/obo/CL_0000235
T2 1399-1411 Body_part denotes erythrocytes http://purl.obolibrary.org/obo/CL_0000232

GlyCosmos15-NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 46-49 OrganismTaxon denotes rat 10114|10116
T3 73-89 OrganismTaxon denotes Escherichia coli 562
T4 197-200 OrganismTaxon denotes rat 10114|10116
T6 271-274 OrganismTaxon denotes rat 10114|10116
T8 557-560 OrganismTaxon denotes rat 10114|10116
T10 636-652 OrganismTaxon denotes Escherichia coli 562
T11 904-909 OrganismTaxon denotes mouse 10088|10090
T13 995-998 OrganismTaxon denotes rat 10114|10116

GlyCosmos15-FMA

Id Subject Object Predicate Lexical cue db_id
T1 201-211 Body_part denotes basophilic FMA:62862
T2 538-549 Body_part denotes macrophages FMA:63261
T3 1399-1411 Body_part denotes erythrocytes FMA:62845

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 538-549 Body_part denotes macrophages http://purl.obolibrary.org/obo/CL_0000235
T2 1399-1411 Body_part denotes erythrocytes http://purl.obolibrary.org/obo/CL_0000232

CL-cell

Id Subject Object Predicate Lexical cue cl_id
T1 112-119 Cell denotes epsilon http://purl.obolibrary.org/obo/CL:0003025
T2 201-211 Cell denotes basophilic http://purl.obolibrary.org/obo/CL:0000767
T3 459-466 Cell denotes epsilon http://purl.obolibrary.org/obo/CL:0003025
T4 538-549 Cell denotes macrophages http://purl.obolibrary.org/obo/CL:0000235|http://purl.obolibrary.org/obo/CL:0000394
T6 561-568 Cell denotes epsilon http://purl.obolibrary.org/obo/CL:0003025
T7 622-629 Cell denotes epsilon http://purl.obolibrary.org/obo/CL:0003025
T8 690-697 Cell denotes epsilon http://purl.obolibrary.org/obo/CL:0003025
T9 872-879 Cell denotes epsilon http://purl.obolibrary.org/obo/CL:0003025
T10 886-893 Cell denotes epsilon http://purl.obolibrary.org/obo/CL:0003025
T11 999-1006 Cell denotes epsilon http://purl.obolibrary.org/obo/CL:0003025
T12 1026-1033 Cell denotes epsilon http://purl.obolibrary.org/obo/CL:0003025
T13 1280-1287 Cell denotes epsilon http://purl.obolibrary.org/obo/CL:0003025
T14 1399-1411 Cell denotes erythrocytes http://purl.obolibrary.org/obo/CL:0000232
T15 1422-1429 Cell denotes epsilon http://purl.obolibrary.org/obo/CL:0003025
T16 1547-1554 Cell denotes epsilon http://purl.obolibrary.org/obo/CL:0003025
T17 1865-1872 Cell denotes epsilon http://purl.obolibrary.org/obo/CL:0003025