PubMed:2249984
Annnotations
GlyCosmos6-Glycan-Motif-Image
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 1105-1124 | Glycan_Motif | denotes | N-acetyllactosamine | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00055MO |
| T2 | 1197-1206 | Glycan_Motif | denotes | galactose | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G68158BT|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G65889KE |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-90 | Sentence | denotes | Expression of biologically active recombinant rat IgE-binding protein in Escherichia coli. |
| T2 | 91-233 | Sentence | denotes | IgE-binding protein (epsilon BP) is a protein which has affinity for IgE and was originally identified in rat basophilic leukemia (RBL) cells. |
| T3 | 234-335 | Sentence | denotes | Subsequently, it was found to be the rat homolog of CBP35, a murine beta-galactoside-specific lectin. |
| T4 | 336-436 | Sentence | denotes | This protein is also designated as L-34 and RL-29 and studied independently by several laboratories. |
| T5 | 437-550 | Sentence | denotes | More recently, CBP35 (epsilon BP) was found to be equivalent to Mac-2, a surface marker on activated macrophages. |
| T6 | 551-653 | Sentence | denotes | Using rat epsilon BP cDNA, we have succeeded in expressing recombinant epsilon BP in Escherichia coli. |
| T7 | 654-855 | Sentence | denotes | Milligram quantities of homogeneous epsilon BP could be obtained from bacterial lysate in a one-step affinity purification procedure utilizing lactosyl-Sepharose 4B and elution with a lactose gradient. |
| T8 | 856-1010 | Sentence | denotes | The recombinant epsilon BP (r epsilon BP) binds mouse IgE and retains reactivity to anti-peptide antibodies specific for a sequence within rat epsilon BP. |
| T9 | 1011-1315 | Sentence | denotes | The purified r epsilon BP exhibits binding activity to various saccharides, with affinity for N-acetyllactosamine greater than thiodigalactoside greater than lactose much greater than D-galactose greater than L-arabinose, an order identical to that exhibited by native epsilon BP isolated from RBL cells. |
| T10 | 1316-1412 | Sentence | denotes | The recombinant lectin displayed hemagglutination activity when tested with rabbit erythrocytes. |
| T11 | 1413-1654 | Sentence | denotes | Although epsilon BP shares sequence homology to other lectins containing S-type (thiol-dependent) carbohydrate-recognition domains, r epsilon BP is resistant to air oxidation and does not require reducing agents for maintaining its activity. |
| T12 | 1655-1811 | Sentence | denotes | Furthermore, the single cysteine residue appears to be unexposed and can be alkylated only when the protein is denatured in 5.6 M guanidinium hydrochloride. |
| T13 | 1812-1985 | Sentence | denotes | The availability of a source for a large quantity of epsilon BP should facilitate the analysis of biological function(s) and structure-activity relationships of this lectin. |
| T1 | 0-90 | Sentence | denotes | Expression of biologically active recombinant rat IgE-binding protein in Escherichia coli. |
| T2 | 91-233 | Sentence | denotes | IgE-binding protein (epsilon BP) is a protein which has affinity for IgE and was originally identified in rat basophilic leukemia (RBL) cells. |
| T3 | 234-335 | Sentence | denotes | Subsequently, it was found to be the rat homolog of CBP35, a murine beta-galactoside-specific lectin. |
| T4 | 336-436 | Sentence | denotes | This protein is also designated as L-34 and RL-29 and studied independently by several laboratories. |
| T5 | 437-550 | Sentence | denotes | More recently, CBP35 (epsilon BP) was found to be equivalent to Mac-2, a surface marker on activated macrophages. |
| T6 | 551-653 | Sentence | denotes | Using rat epsilon BP cDNA, we have succeeded in expressing recombinant epsilon BP in Escherichia coli. |
| T7 | 654-855 | Sentence | denotes | Milligram quantities of homogeneous epsilon BP could be obtained from bacterial lysate in a one-step affinity purification procedure utilizing lactosyl-Sepharose 4B and elution with a lactose gradient. |
| T8 | 856-1010 | Sentence | denotes | The recombinant epsilon BP (r epsilon BP) binds mouse IgE and retains reactivity to anti-peptide antibodies specific for a sequence within rat epsilon BP. |
| T9 | 1011-1315 | Sentence | denotes | The purified r epsilon BP exhibits binding activity to various saccharides, with affinity for N-acetyllactosamine greater than thiodigalactoside greater than lactose much greater than D-galactose greater than L-arabinose, an order identical to that exhibited by native epsilon BP isolated from RBL cells. |
| T10 | 1316-1412 | Sentence | denotes | The recombinant lectin displayed hemagglutination activity when tested with rabbit erythrocytes. |
| T11 | 1413-1654 | Sentence | denotes | Although epsilon BP shares sequence homology to other lectins containing S-type (thiol-dependent) carbohydrate-recognition domains, r epsilon BP is resistant to air oxidation and does not require reducing agents for maintaining its activity. |
| T12 | 1655-1811 | Sentence | denotes | Furthermore, the single cysteine residue appears to be unexposed and can be alkylated only when the protein is denatured in 5.6 M guanidinium hydrochloride. |
| T13 | 1812-1985 | Sentence | denotes | The availability of a source for a large quantity of epsilon BP should facilitate the analysis of biological function(s) and structure-activity relationships of this lectin. |
GlyCosmos6-Glycan-Motif-Structure
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 1105-1124 | https://glytoucan.org/Structures/Glycans/G00055MO | denotes | N-acetyllactosamine |
| T2 | 1197-1206 | https://glytoucan.org/Structures/Glycans/G65889KE | denotes | galactose |
| T3 | 1197-1206 | https://glytoucan.org/Structures/Glycans/G68158BT | denotes | galactose |
PubmedHPO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 212-220 | HP_0001909 | denotes | leukemia |
| T2 | 1399-1411 | HP_0001901 | denotes | erythrocytes |
mondo_disease
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 201-220 | Disease | denotes | basophilic leukemia | http://purl.obolibrary.org/obo/MONDO_0019458 |
HP-phenotype
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 212-220 | Phenotype | denotes | leukemia | HP:0001909 |
Glycan-GlyCosmos
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 838-845 | Glycan | denotes | lactose | https://api.glycosmos.org/wurcs2image/latest/png/binary/G15541SE |
| T2 | 1169-1176 | Glycan | denotes | lactose | https://api.glycosmos.org/wurcs2image/latest/png/binary/G15541SE |
GlyCosmos15-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 212-220 | Phenotype | denotes | leukemia | HP:0001909 |
GlyCosmos15-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 201-220 | Disease | denotes | basophilic leukemia | http://purl.obolibrary.org/obo/MONDO_0019458 |
GlyCosmos15-NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 46-49 | OrganismTaxon | denotes | rat | 10114|10116 |
| T3 | 73-89 | OrganismTaxon | denotes | Escherichia coli | 562 |
| T4 | 197-200 | OrganismTaxon | denotes | rat | 10114|10116 |
| T6 | 271-274 | OrganismTaxon | denotes | rat | 10114|10116 |
| T8 | 557-560 | OrganismTaxon | denotes | rat | 10114|10116 |
| T10 | 636-652 | OrganismTaxon | denotes | Escherichia coli | 562 |
| T11 | 904-909 | OrganismTaxon | denotes | mouse | 10088|10090 |
| T13 | 995-998 | OrganismTaxon | denotes | rat | 10114|10116 |
GlyCosmos15-CL
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 112-119 | Cell | denotes | epsilon | http://purl.obolibrary.org/obo/CL:0003025 |
| T2 | 201-211 | Cell | denotes | basophilic | http://purl.obolibrary.org/obo/CL:0000767 |
| T3 | 459-466 | Cell | denotes | epsilon | http://purl.obolibrary.org/obo/CL:0003025 |
| T4 | 538-549 | Cell | denotes | macrophages | http://purl.obolibrary.org/obo/CL:0000235|http://purl.obolibrary.org/obo/CL:0000394 |
| T6 | 561-568 | Cell | denotes | epsilon | http://purl.obolibrary.org/obo/CL:0003025 |
| T7 | 622-629 | Cell | denotes | epsilon | http://purl.obolibrary.org/obo/CL:0003025 |
| T8 | 690-697 | Cell | denotes | epsilon | http://purl.obolibrary.org/obo/CL:0003025 |
| T9 | 872-879 | Cell | denotes | epsilon | http://purl.obolibrary.org/obo/CL:0003025 |
| T10 | 886-893 | Cell | denotes | epsilon | http://purl.obolibrary.org/obo/CL:0003025 |
| T11 | 999-1006 | Cell | denotes | epsilon | http://purl.obolibrary.org/obo/CL:0003025 |
| T12 | 1026-1033 | Cell | denotes | epsilon | http://purl.obolibrary.org/obo/CL:0003025 |
| T13 | 1280-1287 | Cell | denotes | epsilon | http://purl.obolibrary.org/obo/CL:0003025 |
| T14 | 1399-1411 | Cell | denotes | erythrocytes | http://purl.obolibrary.org/obo/CL:0000232 |
| T15 | 1422-1429 | Cell | denotes | epsilon | http://purl.obolibrary.org/obo/CL:0003025 |
| T16 | 1547-1554 | Cell | denotes | epsilon | http://purl.obolibrary.org/obo/CL:0003025 |
| T17 | 1865-1872 | Cell | denotes | epsilon | http://purl.obolibrary.org/obo/CL:0003025 |
GlyCosmos15-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 538-549 | Body_part | denotes | macrophages | http://purl.obolibrary.org/obo/CL_0000235 |
| T2 | 1399-1411 | Body_part | denotes | erythrocytes | http://purl.obolibrary.org/obo/CL_0000232 |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-90 | Sentence | denotes | Expression of biologically active recombinant rat IgE-binding protein in Escherichia coli. |
| T2 | 91-233 | Sentence | denotes | IgE-binding protein (epsilon BP) is a protein which has affinity for IgE and was originally identified in rat basophilic leukemia (RBL) cells. |
| T3 | 234-335 | Sentence | denotes | Subsequently, it was found to be the rat homolog of CBP35, a murine beta-galactoside-specific lectin. |
| T4 | 336-436 | Sentence | denotes | This protein is also designated as L-34 and RL-29 and studied independently by several laboratories. |
| T5 | 437-550 | Sentence | denotes | More recently, CBP35 (epsilon BP) was found to be equivalent to Mac-2, a surface marker on activated macrophages. |
| T6 | 551-653 | Sentence | denotes | Using rat epsilon BP cDNA, we have succeeded in expressing recombinant epsilon BP in Escherichia coli. |
| T7 | 654-855 | Sentence | denotes | Milligram quantities of homogeneous epsilon BP could be obtained from bacterial lysate in a one-step affinity purification procedure utilizing lactosyl-Sepharose 4B and elution with a lactose gradient. |
| T8 | 856-1010 | Sentence | denotes | The recombinant epsilon BP (r epsilon BP) binds mouse IgE and retains reactivity to anti-peptide antibodies specific for a sequence within rat epsilon BP. |
| T9 | 1011-1315 | Sentence | denotes | The purified r epsilon BP exhibits binding activity to various saccharides, with affinity for N-acetyllactosamine greater than thiodigalactoside greater than lactose much greater than D-galactose greater than L-arabinose, an order identical to that exhibited by native epsilon BP isolated from RBL cells. |
| T10 | 1316-1412 | Sentence | denotes | The recombinant lectin displayed hemagglutination activity when tested with rabbit erythrocytes. |
| T11 | 1413-1654 | Sentence | denotes | Although epsilon BP shares sequence homology to other lectins containing S-type (thiol-dependent) carbohydrate-recognition domains, r epsilon BP is resistant to air oxidation and does not require reducing agents for maintaining its activity. |
| T12 | 1655-1811 | Sentence | denotes | Furthermore, the single cysteine residue appears to be unexposed and can be alkylated only when the protein is denatured in 5.6 M guanidinium hydrochloride. |
| T13 | 1812-1985 | Sentence | denotes | The availability of a source for a large quantity of epsilon BP should facilitate the analysis of biological function(s) and structure-activity relationships of this lectin. |
| T1 | 0-90 | Sentence | denotes | Expression of biologically active recombinant rat IgE-binding protein in Escherichia coli. |
| T2 | 91-233 | Sentence | denotes | IgE-binding protein (epsilon BP) is a protein which has affinity for IgE and was originally identified in rat basophilic leukemia (RBL) cells. |
| T3 | 234-335 | Sentence | denotes | Subsequently, it was found to be the rat homolog of CBP35, a murine beta-galactoside-specific lectin. |
| T4 | 336-436 | Sentence | denotes | This protein is also designated as L-34 and RL-29 and studied independently by several laboratories. |
| T5 | 437-550 | Sentence | denotes | More recently, CBP35 (epsilon BP) was found to be equivalent to Mac-2, a surface marker on activated macrophages. |
| T6 | 551-653 | Sentence | denotes | Using rat epsilon BP cDNA, we have succeeded in expressing recombinant epsilon BP in Escherichia coli. |
| T7 | 654-855 | Sentence | denotes | Milligram quantities of homogeneous epsilon BP could be obtained from bacterial lysate in a one-step affinity purification procedure utilizing lactosyl-Sepharose 4B and elution with a lactose gradient. |
| T8 | 856-1010 | Sentence | denotes | The recombinant epsilon BP (r epsilon BP) binds mouse IgE and retains reactivity to anti-peptide antibodies specific for a sequence within rat epsilon BP. |
| T9 | 1011-1315 | Sentence | denotes | The purified r epsilon BP exhibits binding activity to various saccharides, with affinity for N-acetyllactosamine greater than thiodigalactoside greater than lactose much greater than D-galactose greater than L-arabinose, an order identical to that exhibited by native epsilon BP isolated from RBL cells. |
| T10 | 1316-1412 | Sentence | denotes | The recombinant lectin displayed hemagglutination activity when tested with rabbit erythrocytes. |
| T11 | 1413-1654 | Sentence | denotes | Although epsilon BP shares sequence homology to other lectins containing S-type (thiol-dependent) carbohydrate-recognition domains, r epsilon BP is resistant to air oxidation and does not require reducing agents for maintaining its activity. |
| T12 | 1655-1811 | Sentence | denotes | Furthermore, the single cysteine residue appears to be unexposed and can be alkylated only when the protein is denatured in 5.6 M guanidinium hydrochloride. |
| T13 | 1812-1985 | Sentence | denotes | The availability of a source for a large quantity of epsilon BP should facilitate the analysis of biological function(s) and structure-activity relationships of this lectin. |
GlyCosmos15-Sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-90 | Sentence | denotes | Expression of biologically active recombinant rat IgE-binding protein in Escherichia coli. |
| T2 | 91-233 | Sentence | denotes | IgE-binding protein (epsilon BP) is a protein which has affinity for IgE and was originally identified in rat basophilic leukemia (RBL) cells. |
| T3 | 234-335 | Sentence | denotes | Subsequently, it was found to be the rat homolog of CBP35, a murine beta-galactoside-specific lectin. |
| T4 | 336-436 | Sentence | denotes | This protein is also designated as L-34 and RL-29 and studied independently by several laboratories. |
| T5 | 437-550 | Sentence | denotes | More recently, CBP35 (epsilon BP) was found to be equivalent to Mac-2, a surface marker on activated macrophages. |
| T6 | 551-653 | Sentence | denotes | Using rat epsilon BP cDNA, we have succeeded in expressing recombinant epsilon BP in Escherichia coli. |
| T7 | 654-855 | Sentence | denotes | Milligram quantities of homogeneous epsilon BP could be obtained from bacterial lysate in a one-step affinity purification procedure utilizing lactosyl-Sepharose 4B and elution with a lactose gradient. |
| T8 | 856-1010 | Sentence | denotes | The recombinant epsilon BP (r epsilon BP) binds mouse IgE and retains reactivity to anti-peptide antibodies specific for a sequence within rat epsilon BP. |
| T9 | 1011-1315 | Sentence | denotes | The purified r epsilon BP exhibits binding activity to various saccharides, with affinity for N-acetyllactosamine greater than thiodigalactoside greater than lactose much greater than D-galactose greater than L-arabinose, an order identical to that exhibited by native epsilon BP isolated from RBL cells. |
| T10 | 1316-1412 | Sentence | denotes | The recombinant lectin displayed hemagglutination activity when tested with rabbit erythrocytes. |
| T11 | 1413-1654 | Sentence | denotes | Although epsilon BP shares sequence homology to other lectins containing S-type (thiol-dependent) carbohydrate-recognition domains, r epsilon BP is resistant to air oxidation and does not require reducing agents for maintaining its activity. |
| T12 | 1655-1811 | Sentence | denotes | Furthermore, the single cysteine residue appears to be unexposed and can be alkylated only when the protein is denatured in 5.6 M guanidinium hydrochloride. |
| T13 | 1812-1985 | Sentence | denotes | The availability of a source for a large quantity of epsilon BP should facilitate the analysis of biological function(s) and structure-activity relationships of this lectin. |
GlyCosmos15-Glycan
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 838-845 | Glycan | denotes | lactose | https://api.glycosmos.org/wurcs2image/latest/png/binary/G15541SE |
| T2 | 1169-1176 | Glycan | denotes | lactose | https://api.glycosmos.org/wurcs2image/latest/png/binary/G15541SE |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 46-49 | OrganismTaxon | denotes | rat | 10114|10116 |
| T3 | 73-89 | OrganismTaxon | denotes | Escherichia coli | 562 |
| T4 | 197-200 | OrganismTaxon | denotes | rat | 10114|10116 |
| T6 | 271-274 | OrganismTaxon | denotes | rat | 10114|10116 |
| T8 | 557-560 | OrganismTaxon | denotes | rat | 10114|10116 |
| T10 | 636-652 | OrganismTaxon | denotes | Escherichia coli | 562 |
| T11 | 904-909 | OrganismTaxon | denotes | mouse | 10088|10090 |
| T13 | 995-998 | OrganismTaxon | denotes | rat | 10114|10116 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 538-549 | Body_part | denotes | macrophages | http://purl.obolibrary.org/obo/CL_0000235 |
| T2 | 1399-1411 | Body_part | denotes | erythrocytes | http://purl.obolibrary.org/obo/CL_0000232 |
CL-cell
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 112-119 | Cell | denotes | epsilon | http://purl.obolibrary.org/obo/CL:0003025 |
| T2 | 201-211 | Cell | denotes | basophilic | http://purl.obolibrary.org/obo/CL:0000767 |
| T3 | 459-466 | Cell | denotes | epsilon | http://purl.obolibrary.org/obo/CL:0003025 |
| T4 | 538-549 | Cell | denotes | macrophages | http://purl.obolibrary.org/obo/CL:0000235|http://purl.obolibrary.org/obo/CL:0000394 |
| T6 | 561-568 | Cell | denotes | epsilon | http://purl.obolibrary.org/obo/CL:0003025 |
| T7 | 622-629 | Cell | denotes | epsilon | http://purl.obolibrary.org/obo/CL:0003025 |
| T8 | 690-697 | Cell | denotes | epsilon | http://purl.obolibrary.org/obo/CL:0003025 |
| T9 | 872-879 | Cell | denotes | epsilon | http://purl.obolibrary.org/obo/CL:0003025 |
| T10 | 886-893 | Cell | denotes | epsilon | http://purl.obolibrary.org/obo/CL:0003025 |
| T11 | 999-1006 | Cell | denotes | epsilon | http://purl.obolibrary.org/obo/CL:0003025 |
| T12 | 1026-1033 | Cell | denotes | epsilon | http://purl.obolibrary.org/obo/CL:0003025 |
| T13 | 1280-1287 | Cell | denotes | epsilon | http://purl.obolibrary.org/obo/CL:0003025 |
| T14 | 1399-1411 | Cell | denotes | erythrocytes | http://purl.obolibrary.org/obo/CL:0000232 |
| T15 | 1422-1429 | Cell | denotes | epsilon | http://purl.obolibrary.org/obo/CL:0003025 |
| T16 | 1547-1554 | Cell | denotes | epsilon | http://purl.obolibrary.org/obo/CL:0003025 |
| T17 | 1865-1872 | Cell | denotes | epsilon | http://purl.obolibrary.org/obo/CL:0003025 |