PubMed:22411838
Annnotations
Glycan-Motif
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 19-40 | https://glytoucan.org/Structures/Glycans/G06239NA | denotes | lactotriaosylceramide |
| T2 | 19-40 | https://glytoucan.org/Structures/Glycans/G87727XV | denotes | lactotriaosylceramide |
| T3 | 718-721 | https://glytoucan.org/Structures/Glycans/G06239NA | denotes | Lc3 |
| T4 | 724-727 | https://glytoucan.org/Structures/Glycans/G56516VH | denotes | GM3 |
| T5 | 724-727 | https://glytoucan.org/Structures/Glycans/G91237TK | denotes | GM3 |
| T6 | 732-757 | https://glytoucan.org/Structures/Glycans/G58896AZ | denotes | neolactotetraosylceramide |
| T7 | 907-910 | https://glytoucan.org/Structures/Glycans/G06239NA | denotes | Lc3 |
| T8 | 946-949 | https://glytoucan.org/Structures/Glycans/G06239NA | denotes | Lc3 |
| T9 | 1189-1192 | https://glytoucan.org/Structures/Glycans/G06239NA | denotes | Lc3 |
| T10 | 1194-1197 | https://glytoucan.org/Structures/Glycans/G56516VH | denotes | GM3 |
| T11 | 1194-1197 | https://glytoucan.org/Structures/Glycans/G91237TK | denotes | GM3 |
GGDB-2020
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 724-727 | https://acgg.asia/db/ggdb/info/gg052 | denotes | GM3 |
| T2 | 1194-1197 | https://acgg.asia/db/ggdb/info/gg052 | denotes | GM3 |
ggdb-test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 724-727 | https://acgg.asia/db/ggdb/info/gg052 | denotes | GM3 |
| T2 | 1194-1197 | https://acgg.asia/db/ggdb/info/gg052 | denotes | GM3 |
GlyCosmos6-Glycan-Motif-Image
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 19-40 | Glycan_Motif | denotes | lactotriaosylceramide | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G87727XV|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G06239NA |
| T3 | 695-716 | Glycan_Motif | denotes | lactotriaosylceramide | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G87727XV|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G06239NA |
| T5 | 718-721 | Glycan_Motif | denotes | Lc3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G06239NA |
| T6 | 724-727 | Glycan_Motif | denotes | GM3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G91237TK|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G56516VH |
| T8 | 732-757 | Glycan_Motif | denotes | neolactotetraosylceramide | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G58896AZ |
| T9 | 907-910 | Glycan_Motif | denotes | Lc3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G06239NA |
| T10 | 946-949 | Glycan_Motif | denotes | Lc3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G06239NA |
| T11 | 1189-1192 | Glycan_Motif | denotes | Lc3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G06239NA |
| T12 | 1194-1197 | Glycan_Motif | denotes | GM3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G91237TK|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G56516VH |
Glycosmos6-MAT
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 97-108 | http://purl.obolibrary.org/obo/MAT_0000084 | denotes | bone marrow |
| T2 | 97-101 | http://purl.obolibrary.org/obo/MAT_0000299 | denotes | bone |
| T3 | 446-457 | http://purl.obolibrary.org/obo/MAT_0000084 | denotes | bone marrow |
| T4 | 446-450 | http://purl.obolibrary.org/obo/MAT_0000299 | denotes | bone |
| T5 | 774-785 | http://purl.obolibrary.org/obo/MAT_0000084 | denotes | bone marrow |
| T6 | 774-778 | http://purl.obolibrary.org/obo/MAT_0000299 | denotes | bone |
| T7 | 1026-1037 | http://purl.obolibrary.org/obo/MAT_0000084 | denotes | bone marrow |
| T8 | 1026-1030 | http://purl.obolibrary.org/obo/MAT_0000299 | denotes | bone |
GlyCosmos6-Glycan-Motif-Structure
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 19-40 | https://glytoucan.org/Structures/Glycans/G06239NA | denotes | lactotriaosylceramide |
| T2 | 19-40 | https://glytoucan.org/Structures/Glycans/G87727XV | denotes | lactotriaosylceramide |
| T3 | 718-721 | https://glytoucan.org/Structures/Glycans/G06239NA | denotes | Lc3 |
| T4 | 724-727 | https://glytoucan.org/Structures/Glycans/G56516VH | denotes | GM3 |
| T5 | 724-727 | https://glytoucan.org/Structures/Glycans/G91237TK | denotes | GM3 |
| T6 | 732-757 | https://glytoucan.org/Structures/Glycans/G58896AZ | denotes | neolactotetraosylceramide |
| T7 | 907-910 | https://glytoucan.org/Structures/Glycans/G06239NA | denotes | Lc3 |
| T8 | 946-949 | https://glytoucan.org/Structures/Glycans/G06239NA | denotes | Lc3 |
| T9 | 1189-1192 | https://glytoucan.org/Structures/Glycans/G06239NA | denotes | Lc3 |
| T10 | 1194-1197 | https://glytoucan.org/Structures/Glycans/G56516VH | denotes | GM3 |
| T11 | 1194-1197 | https://glytoucan.org/Structures/Glycans/G91237TK | denotes | GM3 |
DisGeNET
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T0 | 691-694 | gene:5476 | denotes | GSL |
| T1 | 855-858 | disease:C0023467 | denotes | AML |
| R1 | T0 | T1 | associated_with | GSL,AML |
PubmedHPO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 382-404 | HP_0004808 | denotes | acute myeloid leukemia |
| T2 | 388-404 | HP_0012324 | denotes | myeloid leukemia |
| T3 | 396-404 | HP_0001909 | denotes | leukemia |
GlycoBiology-GDGDB
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| _T1 | 165-169 | http://acgg.asia/db/diseases/gdgdb?con_ui=CON00023 | denotes | GSLs |
| _T2 | 338-342 | http://acgg.asia/db/diseases/gdgdb?con_ui=CON00023 | denotes | GSLs |
| _T3 | 520-523 | http://acgg.asia/db/diseases/gdgdb?con_ui=CON00023 | denotes | GSL |
| _T4 | 691-694 | http://acgg.asia/db/diseases/gdgdb?con_ui=CON00023 | denotes | GSL |
| _T5 | 1184-1188 | http://acgg.asia/db/diseases/gdgdb?con_ui=CON00023 | denotes | GSLs |
GlycoBiology-FMA
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| _T1 | 71-88 | FMAID:82815 | denotes | glycosphingolipid |
| _T2 | 71-88 | FMAID:196810 | denotes | glycosphingolipid |
| _T3 | 71-88 | FMAID:82813 | denotes | glycosphingolipid |
| _T4 | 71-88 | FMAID:196808 | denotes | glycosphingolipid |
| _T5 | 71-88 | FMAID:82811 | denotes | glycosphingolipid |
| _T6 | 71-88 | FMAID:196806 | denotes | glycosphingolipid |
| _T7 | 71-88 | FMAID:82814 | denotes | glycosphingolipid |
| _T8 | 71-88 | FMAID:196813 | denotes | glycosphingolipid |
| _T9 | 71-88 | FMAID:82818 | denotes | glycosphingolipid |
| _T10 | 71-88 | FMAID:196815 | denotes | glycosphingolipid |
| _T11 | 71-88 | FMAID:196814 | denotes | glycosphingolipid |
| _T12 | 71-88 | FMAID:196809 | denotes | glycosphingolipid |
| _T13 | 71-88 | FMAID:82812 | denotes | glycosphingolipid |
| _T14 | 71-88 | FMAID:196807 | denotes | glycosphingolipid |
| _T15 | 71-88 | FMAID:82817 | denotes | glycosphingolipid |
| _T16 | 71-88 | FMAID:196812 | denotes | glycosphingolipid |
| _T17 | 71-88 | FMAID:82819 | denotes | glycosphingolipid |
| _T18 | 97-101 | FMAID:123537 | denotes | bone |
| _T19 | 97-101 | FMAID:172618 | denotes | bone |
| _T20 | 97-101 | FMAID:30317 | denotes | bone |
| _T21 | 97-108 | FMAID:97498 | denotes | bone marrow |
| _T22 | 97-108 | FMAID:9608 | denotes | bone marrow |
| _T23 | 145-163 | FMAID:196814 | denotes | Glycosphingolipids |
| _T24 | 145-163 | FMAID:82813 | denotes | Glycosphingolipids |
| _T25 | 145-163 | FMAID:196808 | denotes | Glycosphingolipids |
| _T26 | 145-163 | FMAID:82815 | denotes | Glycosphingolipids |
| _T27 | 145-163 | FMAID:196810 | denotes | Glycosphingolipids |
| _T28 | 145-163 | FMAID:82818 | denotes | Glycosphingolipids |
| _T29 | 145-163 | FMAID:82811 | denotes | Glycosphingolipids |
| _T30 | 145-163 | FMAID:196806 | denotes | Glycosphingolipids |
| _T31 | 145-163 | FMAID:196813 | denotes | Glycosphingolipids |
| _T32 | 145-163 | FMAID:196815 | denotes | Glycosphingolipids |
| _T33 | 145-163 | FMAID:82814 | denotes | Glycosphingolipids |
| _T34 | 145-163 | FMAID:196809 | denotes | Glycosphingolipids |
| _T35 | 145-163 | FMAID:82819 | denotes | Glycosphingolipids |
| _T36 | 145-163 | FMAID:196807 | denotes | Glycosphingolipids |
| _T37 | 145-163 | FMAID:196812 | denotes | Glycosphingolipids |
| _T38 | 145-163 | FMAID:82817 | denotes | Glycosphingolipids |
| _T39 | 145-163 | FMAID:82812 | denotes | Glycosphingolipids |
| _T40 | 411-416 | FMAID:169002 | denotes | cells |
| _T41 | 411-416 | FMAID:68646 | denotes | cells |
| _T42 | 446-450 | FMAID:172618 | denotes | bone |
| _T43 | 446-450 | FMAID:30317 | denotes | bone |
| _T44 | 446-450 | FMAID:123537 | denotes | bone |
| _T45 | 446-457 | FMAID:97498 | denotes | bone marrow |
| _T46 | 446-457 | FMAID:9608 | denotes | bone marrow |
| _T47 | 774-778 | FMAID:172618 | denotes | bone |
| _T48 | 774-778 | FMAID:30317 | denotes | bone |
| _T49 | 774-778 | FMAID:123537 | denotes | bone |
| _T50 | 774-785 | FMAID:97498 | denotes | bone marrow |
| _T51 | 774-785 | FMAID:9608 | denotes | bone marrow |
| _T52 | 1003-1005 | FMAID:167735 | denotes | T5 |
| _T53 | 1003-1005 | FMAID:63507 | denotes | T5 |
| _T54 | 1026-1030 | FMAID:30317 | denotes | bone |
| _T55 | 1026-1030 | FMAID:123537 | denotes | bone |
| _T56 | 1026-1030 | FMAID:172618 | denotes | bone |
| _T57 | 1026-1037 | FMAID:9608 | denotes | bone marrow |
| _T58 | 1026-1037 | FMAID:97498 | denotes | bone marrow |
| _T59 | 1100-1102 | FMAID:167735 | denotes | T5 |
| _T60 | 1100-1102 | FMAID:63507 | denotes | T5 |
uniprot-human
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 601-605 | http://www.uniprot.org/uniprot/Q9UFF0 | denotes | trap |
| T2 | 946-958 | http://www.uniprot.org/uniprot/Q9BYG0 | denotes | Lc3 synthase |
| T3 | 998-1005 | http://www.uniprot.org/uniprot/Q9BYG0 | denotes | β3Gn-T5 |
| T4 | 1095-1102 | http://www.uniprot.org/uniprot/Q9BYG0 | denotes | β3Gn-T5 |
uniprot-mouse
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 601-605 | http://www.uniprot.org/uniprot/Q05117 | denotes | trap |
| T2 | 601-605 | http://www.uniprot.org/uniprot/Q8K1H1 | denotes | trap |
| T3 | 946-958 | http://www.uniprot.org/uniprot/Q8BGY6 | denotes | Lc3 synthase |
| T4 | 998-1005 | http://www.uniprot.org/uniprot/Q8BGY6 | denotes | β3Gn-T5 |
| T5 | 1095-1102 | http://www.uniprot.org/uniprot/Q8BGY6 | denotes | β3Gn-T5 |
GlycoBiology-NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 411-416 | http://purl.bioontology.org/ontology/STY/T025 | denotes | cells |
| T2 | 893-903 | http://purl.bioontology.org/ontology/NCBITAXON/127244 | denotes | mechanisms |
GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 236-257 | http://purl.obolibrary.org/obo/GO_0009790 | denotes | embryonic development |
| T2 | 246-257 | http://purl.obolibrary.org/obo/GO_0032502 | denotes | development |
| T3 | 259-265 | http://purl.obolibrary.org/obo/GO_0023052 | denotes | signal |
| T4 | 259-278 | http://purl.obolibrary.org/obo/GO_0007165 | denotes | signal transduction |
| T5 | 266-278 | http://purl.obolibrary.org/obo/GO_0009293 | denotes | transduction |
GO-CC
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 411-416 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
UBERON-AE
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 97-108 | http://purl.obolibrary.org/obo/UBERON_0002371 | denotes | bone marrow |
| T2 | 446-457 | http://purl.obolibrary.org/obo/UBERON_0002371 | denotes | bone marrow |
| T3 | 774-785 | http://purl.obolibrary.org/obo/UBERON_0002371 | denotes | bone marrow |
| T4 | 1026-1037 | http://purl.obolibrary.org/obo/UBERON_0002371 | denotes | bone marrow |
Allie
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| SS1_22411838_1_0 | 145-163 | expanded | denotes | Glycosphingolipids |
| SS2_22411838_1_0 | 165-169 | abbr | denotes | GSLs |
| SS1_22411838_2_0 | 382-404 | expanded | denotes | acute myeloid leukemia |
| SS2_22411838_2_0 | 406-409 | abbr | denotes | AML |
| SS1_22411838_5_0 | 959-996 | expanded | denotes | β1,3-N-acetylglucosaminyltransferase5 |
| SS2_22411838_5_0 | 998-1005 | abbr | denotes | β3Gn-T5 |
| AE1_22411838_1_0 | SS1_22411838_1_0 | SS2_22411838_1_0 | abbreviatedTo | Glycosphingolipids,GSLs |
| AE1_22411838_2_0 | SS1_22411838_2_0 | SS2_22411838_2_0 | abbreviatedTo | acute myeloid leukemia,AML |
| AE1_22411838_5_0 | SS1_22411838_5_0 | SS2_22411838_5_0 | abbreviatedTo | "β1,3-N-acetylglucosaminyltransferase5",β3Gn-T5 |
EDAM-topics
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 308-315 | http://edamontology.org/topic_3678 | denotes | studies |
| T2 | 426-431 | http://edamontology.org/topic_3678 | denotes | study |
| T3 | 458-465 | http://edamontology.org/topic_3277 | denotes | samples |
| T4 | 520-543 | http://edamontology.org/topic_0203 | denotes | GSL expression profiles |
| T5 | 524-543 | http://edamontology.org/topic_0203 | denotes | expression profiles |
| T6 | 606-623 | http://edamontology.org/topic_3520 | denotes | mass spectrometry |
| T7 | 606-623 | http://edamontology.org/topic_0134 | denotes | mass spectrometry |
| T8 | 1038-1045 | http://edamontology.org/topic_3277 | denotes | samples |
EDAM-DFO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 520-543 | http://edamontology.org/operation_0314 | denotes | GSL expression profiles |
| T2 | 520-543 | http://edamontology.org/data_0928 | denotes | GSL expression profiles |
| T3 | 524-543 | http://edamontology.org/operation_3232 | denotes | expression profiles |
| T4 | 524-543 | http://edamontology.org/operation_0314 | denotes | expression profiles |
| T5 | 606-623 | http://edamontology.org/data_2536 | denotes | mass spectrometry |
| T6 | 606-623 | http://edamontology.org/data_3147 | denotes | mass spectrometry |
GlycoBiology-MAT
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 97-101 | http://purl.obolibrary.org/obo/MAT_0000299 | denotes | bone |
| T2 | 97-108 | http://purl.obolibrary.org/obo/MAT_0000084 | denotes | bone marrow |
| T3 | 446-450 | http://purl.obolibrary.org/obo/MAT_0000299 | denotes | bone |
| T4 | 446-457 | http://purl.obolibrary.org/obo/MAT_0000084 | denotes | bone marrow |
| T5 | 774-778 | http://purl.obolibrary.org/obo/MAT_0000299 | denotes | bone |
| T6 | 774-785 | http://purl.obolibrary.org/obo/MAT_0000084 | denotes | bone marrow |
| T7 | 1026-1030 | http://purl.obolibrary.org/obo/MAT_0000299 | denotes | bone |
| T8 | 1026-1037 | http://purl.obolibrary.org/obo/MAT_0000084 | denotes | bone marrow |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| TextSentencer_T1 | 0-144 | Sentence | denotes | High expression of lactotriaosylceramide, a differentiation-associated glycosphingolipid, in the bone marrow of acute myeloid leukemia patients. |
| TextSentencer_T2 | 145-298 | Sentence | denotes | Glycosphingolipids (GSLs) are information-bearing biomolecules that play critical roles in embryonic development, signal transduction and carcinogenesis. |
| TextSentencer_T3 | 299-417 | Sentence | denotes | Previous studies indicate that certain GSLs are associated with differentiation in acute myeloid leukemia (AML) cells. |
| TextSentencer_T4 | 418-624 | Sentence | denotes | In this study, we collected bone marrow samples from healthy donors and AML patients and analyzed the GSL expression profiles comprehensively using electrospray ionization linear ion-trap mass spectrometry. |
| TextSentencer_T5 | 625-859 | Sentence | denotes | The results showed that AML patients had higher expression of the GSL lactotriaosylceramide (Lc3), GM3 and neolactotetraosylceramide (nLc4) in their bone marrow than did the healthy donors (P < 0.05), especially the M1 subtype of AML. |
| TextSentencer_T6 | 860-1143 | Sentence | denotes | To further explore the molecular mechanisms of Lc3, we examined the expression of the Lc3 synthase β1,3-N-acetylglucosaminyltransferase5 (β3Gn-T5) and found that the bone marrow samples of AML patients had 16-fold higher expression of β3Gn-T5 than those of healthy donors (P < 0.05). |
| TextSentencer_T7 | 1144-1270 | Sentence | denotes | Our results suggest that AML-associated GSLs Lc3, GM3 and nLc4 are possibly involved in initiation and differentiation of AML. |
| T1 | 0-144 | Sentence | denotes | High expression of lactotriaosylceramide, a differentiation-associated glycosphingolipid, in the bone marrow of acute myeloid leukemia patients. |
| T2 | 145-298 | Sentence | denotes | Glycosphingolipids (GSLs) are information-bearing biomolecules that play critical roles in embryonic development, signal transduction and carcinogenesis. |
| T3 | 299-417 | Sentence | denotes | Previous studies indicate that certain GSLs are associated with differentiation in acute myeloid leukemia (AML) cells. |
| T4 | 418-624 | Sentence | denotes | In this study, we collected bone marrow samples from healthy donors and AML patients and analyzed the GSL expression profiles comprehensively using electrospray ionization linear ion-trap mass spectrometry. |
| T5 | 625-859 | Sentence | denotes | The results showed that AML patients had higher expression of the GSL lactotriaosylceramide (Lc3), GM3 and neolactotetraosylceramide (nLc4) in their bone marrow than did the healthy donors (P < 0.05), especially the M1 subtype of AML. |
| T6 | 860-1143 | Sentence | denotes | To further explore the molecular mechanisms of Lc3, we examined the expression of the Lc3 synthase β1,3-N-acetylglucosaminyltransferase5 (β3Gn-T5) and found that the bone marrow samples of AML patients had 16-fold higher expression of β3Gn-T5 than those of healthy donors (P < 0.05). |
| T7 | 1144-1270 | Sentence | denotes | Our results suggest that AML-associated GSLs Lc3, GM3 and nLc4 are possibly involved in initiation and differentiation of AML. |
| T1 | 0-144 | Sentence | denotes | High expression of lactotriaosylceramide, a differentiation-associated glycosphingolipid, in the bone marrow of acute myeloid leukemia patients. |
| T2 | 145-298 | Sentence | denotes | Glycosphingolipids (GSLs) are information-bearing biomolecules that play critical roles in embryonic development, signal transduction and carcinogenesis. |
| T3 | 299-417 | Sentence | denotes | Previous studies indicate that certain GSLs are associated with differentiation in acute myeloid leukemia (AML) cells. |
| T4 | 418-624 | Sentence | denotes | In this study, we collected bone marrow samples from healthy donors and AML patients and analyzed the GSL expression profiles comprehensively using electrospray ionization linear ion-trap mass spectrometry. |
| T5 | 625-859 | Sentence | denotes | The results showed that AML patients had higher expression of the GSL lactotriaosylceramide (Lc3), GM3 and neolactotetraosylceramide (nLc4) in their bone marrow than did the healthy donors (P < 0.05), especially the M1 subtype of AML. |
| T6 | 860-1143 | Sentence | denotes | To further explore the molecular mechanisms of Lc3, we examined the expression of the Lc3 synthase β1,3-N-acetylglucosaminyltransferase5 (β3Gn-T5) and found that the bone marrow samples of AML patients had 16-fold higher expression of β3Gn-T5 than those of healthy donors (P < 0.05). |
| T7 | 1144-1270 | Sentence | denotes | Our results suggest that AML-associated GSLs Lc3, GM3 and nLc4 are possibly involved in initiation and differentiation of AML. |
performance-test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| PD-UBERON-AE-B_T1 | 97-108 | http://purl.obolibrary.org/obo/UBERON_0002371 | denotes | bone marrow |
| PD-UBERON-AE-B_T2 | 446-457 | http://purl.obolibrary.org/obo/UBERON_0002371 | denotes | bone marrow |
| PD-UBERON-AE-B_T3 | 774-785 | http://purl.obolibrary.org/obo/UBERON_0002371 | denotes | bone marrow |
| PD-UBERON-AE-B_T4 | 1026-1037 | http://purl.obolibrary.org/obo/UBERON_0002371 | denotes | bone marrow |
mondo_disease
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 112-134 | Disease | denotes | acute myeloid leukemia | http://purl.obolibrary.org/obo/MONDO_0015667|http://purl.obolibrary.org/obo/MONDO_0018874 |
| T3 | 382-410 | Disease | denotes | acute myeloid leukemia (AML) | http://purl.obolibrary.org/obo/MONDO_0004996|http://purl.obolibrary.org/obo/MONDO_0018874 |
| T5 | 490-493 | Disease | denotes | AML | http://purl.obolibrary.org/obo/MONDO_0018874 |
| T6 | 649-652 | Disease | denotes | AML | http://purl.obolibrary.org/obo/MONDO_0018874 |
| T7 | 855-858 | Disease | denotes | AML | http://purl.obolibrary.org/obo/MONDO_0018874 |
| T8 | 1049-1052 | Disease | denotes | AML | http://purl.obolibrary.org/obo/MONDO_0018874 |
| T9 | 1169-1172 | Disease | denotes | AML | http://purl.obolibrary.org/obo/MONDO_0018874 |
| T10 | 1266-1269 | Disease | denotes | AML | http://purl.obolibrary.org/obo/MONDO_0018874 |
Glycan-GlyCosmos
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 718-721 | Glycan | denotes | Lc3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G06239NA |
| T2 | 724-727 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T3 | 759-763 | Glycan | denotes | nLc4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G58896AZ |
| T4 | 907-910 | Glycan | denotes | Lc3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G06239NA |
| T5 | 946-949 | Glycan | denotes | Lc3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G06239NA |
| T6 | 1189-1192 | Glycan | denotes | Lc3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G06239NA |
| T7 | 1194-1197 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T8 | 1202-1206 | Glycan | denotes | nLc4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G58896AZ |
GlyCosmos15-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 112-134 | Phenotype | denotes | acute myeloid leukemia | HP:0004808 |
| T2 | 382-404 | Phenotype | denotes | acute myeloid leukemia | HP:0004808 |
| T3 | 406-409 | Phenotype | denotes | AML | HP:0004808 |
| T4 | 490-493 | Phenotype | denotes | AML | HP:0004808 |
| T5 | 649-652 | Phenotype | denotes | AML | HP:0004808 |
| T6 | 855-858 | Phenotype | denotes | AML | HP:0004808 |
| T7 | 1049-1052 | Phenotype | denotes | AML | HP:0004808 |
| T8 | 1169-1172 | Phenotype | denotes | AML | HP:0004808 |
| T9 | 1266-1269 | Phenotype | denotes | AML | HP:0004808 |
GlyCosmos15-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 97-108 | Body_part | denotes | bone marrow | http://purl.obolibrary.org/obo/UBERON_0002371 |
| T2 | 446-457 | Body_part | denotes | bone marrow | http://purl.obolibrary.org/obo/UBERON_0002371 |
| T3 | 774-785 | Body_part | denotes | bone marrow | http://purl.obolibrary.org/obo/UBERON_0002371 |
| T4 | 1026-1037 | Body_part | denotes | bone marrow | http://purl.obolibrary.org/obo/UBERON_0002371 |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| TextSentencer_T1 | 0-144 | Sentence | denotes | High expression of lactotriaosylceramide, a differentiation-associated glycosphingolipid, in the bone marrow of acute myeloid leukemia patients. |
| TextSentencer_T2 | 145-298 | Sentence | denotes | Glycosphingolipids (GSLs) are information-bearing biomolecules that play critical roles in embryonic development, signal transduction and carcinogenesis. |
| TextSentencer_T3 | 299-417 | Sentence | denotes | Previous studies indicate that certain GSLs are associated with differentiation in acute myeloid leukemia (AML) cells. |
| TextSentencer_T4 | 418-624 | Sentence | denotes | In this study, we collected bone marrow samples from healthy donors and AML patients and analyzed the GSL expression profiles comprehensively using electrospray ionization linear ion-trap mass spectrometry. |
| TextSentencer_T5 | 625-859 | Sentence | denotes | The results showed that AML patients had higher expression of the GSL lactotriaosylceramide (Lc3), GM3 and neolactotetraosylceramide (nLc4) in their bone marrow than did the healthy donors (P < 0.05), especially the M1 subtype of AML. |
| TextSentencer_T6 | 860-1143 | Sentence | denotes | To further explore the molecular mechanisms of Lc3, we examined the expression of the Lc3 synthase β1,3-N-acetylglucosaminyltransferase5 (β3Gn-T5) and found that the bone marrow samples of AML patients had 16-fold higher expression of β3Gn-T5 than those of healthy donors (P < 0.05). |
| TextSentencer_T7 | 1144-1270 | Sentence | denotes | Our results suggest that AML-associated GSLs Lc3, GM3 and nLc4 are possibly involved in initiation and differentiation of AML. |
| T1 | 0-144 | Sentence | denotes | High expression of lactotriaosylceramide, a differentiation-associated glycosphingolipid, in the bone marrow of acute myeloid leukemia patients. |
| T2 | 145-298 | Sentence | denotes | Glycosphingolipids (GSLs) are information-bearing biomolecules that play critical roles in embryonic development, signal transduction and carcinogenesis. |
| T3 | 299-417 | Sentence | denotes | Previous studies indicate that certain GSLs are associated with differentiation in acute myeloid leukemia (AML) cells. |
| T4 | 418-624 | Sentence | denotes | In this study, we collected bone marrow samples from healthy donors and AML patients and analyzed the GSL expression profiles comprehensively using electrospray ionization linear ion-trap mass spectrometry. |
| T5 | 625-859 | Sentence | denotes | The results showed that AML patients had higher expression of the GSL lactotriaosylceramide (Lc3), GM3 and neolactotetraosylceramide (nLc4) in their bone marrow than did the healthy donors (P < 0.05), especially the M1 subtype of AML. |
| T6 | 860-1143 | Sentence | denotes | To further explore the molecular mechanisms of Lc3, we examined the expression of the Lc3 synthase β1,3-N-acetylglucosaminyltransferase5 (β3Gn-T5) and found that the bone marrow samples of AML patients had 16-fold higher expression of β3Gn-T5 than those of healthy donors (P < 0.05). |
| T7 | 1144-1270 | Sentence | denotes | Our results suggest that AML-associated GSLs Lc3, GM3 and nLc4 are possibly involved in initiation and differentiation of AML. |
| T1 | 0-144 | Sentence | denotes | High expression of lactotriaosylceramide, a differentiation-associated glycosphingolipid, in the bone marrow of acute myeloid leukemia patients. |
| T2 | 145-298 | Sentence | denotes | Glycosphingolipids (GSLs) are information-bearing biomolecules that play critical roles in embryonic development, signal transduction and carcinogenesis. |
| T3 | 299-417 | Sentence | denotes | Previous studies indicate that certain GSLs are associated with differentiation in acute myeloid leukemia (AML) cells. |
| T4 | 418-624 | Sentence | denotes | In this study, we collected bone marrow samples from healthy donors and AML patients and analyzed the GSL expression profiles comprehensively using electrospray ionization linear ion-trap mass spectrometry. |
| T5 | 625-859 | Sentence | denotes | The results showed that AML patients had higher expression of the GSL lactotriaosylceramide (Lc3), GM3 and neolactotetraosylceramide (nLc4) in their bone marrow than did the healthy donors (P < 0.05), especially the M1 subtype of AML. |
| T6 | 860-1143 | Sentence | denotes | To further explore the molecular mechanisms of Lc3, we examined the expression of the Lc3 synthase β1,3-N-acetylglucosaminyltransferase5 (β3Gn-T5) and found that the bone marrow samples of AML patients had 16-fold higher expression of β3Gn-T5 than those of healthy donors (P < 0.05). |
| T7 | 1144-1270 | Sentence | denotes | Our results suggest that AML-associated GSLs Lc3, GM3 and nLc4 are possibly involved in initiation and differentiation of AML. |
GlyCosmos15-Sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-144 | Sentence | denotes | High expression of lactotriaosylceramide, a differentiation-associated glycosphingolipid, in the bone marrow of acute myeloid leukemia patients. |
| T2 | 145-298 | Sentence | denotes | Glycosphingolipids (GSLs) are information-bearing biomolecules that play critical roles in embryonic development, signal transduction and carcinogenesis. |
| T3 | 299-417 | Sentence | denotes | Previous studies indicate that certain GSLs are associated with differentiation in acute myeloid leukemia (AML) cells. |
| T4 | 418-624 | Sentence | denotes | In this study, we collected bone marrow samples from healthy donors and AML patients and analyzed the GSL expression profiles comprehensively using electrospray ionization linear ion-trap mass spectrometry. |
| T5 | 625-859 | Sentence | denotes | The results showed that AML patients had higher expression of the GSL lactotriaosylceramide (Lc3), GM3 and neolactotetraosylceramide (nLc4) in their bone marrow than did the healthy donors (P < 0.05), especially the M1 subtype of AML. |
| T6 | 860-1143 | Sentence | denotes | To further explore the molecular mechanisms of Lc3, we examined the expression of the Lc3 synthase β1,3-N-acetylglucosaminyltransferase5 (β3Gn-T5) and found that the bone marrow samples of AML patients had 16-fold higher expression of β3Gn-T5 than those of healthy donors (P < 0.05). |
| T7 | 1144-1270 | Sentence | denotes | Our results suggest that AML-associated GSLs Lc3, GM3 and nLc4 are possibly involved in initiation and differentiation of AML. |
GlyCosmos15-Glycan
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 718-721 | Glycan | denotes | Lc3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G06239NA |
| T2 | 724-727 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T3 | 759-763 | Glycan | denotes | nLc4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G58896AZ |
| T4 | 907-910 | Glycan | denotes | Lc3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G06239NA |
| T5 | 946-949 | Glycan | denotes | Lc3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G06239NA |
| T6 | 1189-1192 | Glycan | denotes | Lc3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G06239NA |
| T7 | 1194-1197 | Glycan | denotes | GM3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK |
| T8 | 1202-1206 | Glycan | denotes | nLc4 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G58896AZ |
GlyCosmos15-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 112-134 | Disease | denotes | acute myeloid leukemia | MONDO:0015667|MONDO:0018874 |
| T3 | 382-410 | Disease | denotes | acute myeloid leukemia (AML) | MONDO:0004996|MONDO:0018874 |
GlyCosmos15-FMA
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 97-108 | Body_part | denotes | bone marrow | FMA:9608 |
| T2 | 446-457 | Body_part | denotes | bone marrow | FMA:9608 |
| T3 | 774-785 | Body_part | denotes | bone marrow | FMA:9608 |
| T4 | 1026-1037 | Body_part | denotes | bone marrow | FMA:9608 |
GlyCosmos15-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 97-108 | Body_part | denotes | bone marrow | http://purl.obolibrary.org/obo/MAT_0000084 |
| T2 | 446-457 | Body_part | denotes | bone marrow | http://purl.obolibrary.org/obo/MAT_0000084 |
| T3 | 774-785 | Body_part | denotes | bone marrow | http://purl.obolibrary.org/obo/MAT_0000084 |
| T4 | 1026-1037 | Body_part | denotes | bone marrow | http://purl.obolibrary.org/obo/MAT_0000084 |
Anatomy-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 97-108 | Body_part | denotes | bone marrow | http://purl.obolibrary.org/obo/MAT_0000084 |
| T2 | 446-457 | Body_part | denotes | bone marrow | http://purl.obolibrary.org/obo/MAT_0000084 |
| T3 | 774-785 | Body_part | denotes | bone marrow | http://purl.obolibrary.org/obo/MAT_0000084 |
| T4 | 1026-1037 | Body_part | denotes | bone marrow | http://purl.obolibrary.org/obo/MAT_0000084 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 97-108 | Body_part | denotes | bone marrow | http://purl.obolibrary.org/obo/UBERON_0002371 |
| T2 | 446-457 | Body_part | denotes | bone marrow | http://purl.obolibrary.org/obo/UBERON_0002371 |
| T3 | 774-785 | Body_part | denotes | bone marrow | http://purl.obolibrary.org/obo/UBERON_0002371 |
| T4 | 1026-1037 | Body_part | denotes | bone marrow | http://purl.obolibrary.org/obo/UBERON_0002371 |
HP-phenotype
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 112-134 | Phenotype | denotes | acute myeloid leukemia | HP:0004808 |
| T2 | 382-404 | Phenotype | denotes | acute myeloid leukemia | HP:0004808 |
| T3 | 406-409 | Phenotype | denotes | AML | HP:0004808 |
| T4 | 490-493 | Phenotype | denotes | AML | HP:0004808 |
| T5 | 649-652 | Phenotype | denotes | AML | HP:0004808 |
| T6 | 855-858 | Phenotype | denotes | AML | HP:0004808 |
| T7 | 1049-1052 | Phenotype | denotes | AML | HP:0004808 |
| T8 | 1169-1172 | Phenotype | denotes | AML | HP:0004808 |
| T9 | 1266-1269 | Phenotype | denotes | AML | HP:0004808 |