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sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-194 Sentence denotes Characterization of exogenous bacterial oligosaccharyltransferases in Escherichia coli reveals the potential for O-linked protein glycosylation in Vibrio cholerae and Burkholderia thailandensis.
TextSentencer_T2 195-313 Sentence denotes Bacterial protein glycosylation systems from varying species have been functionally reconstituted in Escherichia coli.
TextSentencer_T3 314-544 Sentence denotes Both N- and O-linked glycosylation pathways, in which the glycans are first assembled onto lipid carriers and subsequently transferred to acceptor proteins by an oligosaccharyltransferase (OTase), have been documented in bacteria.
TextSentencer_T4 545-708 Sentence denotes The identification and characterization of novel OTases with different properties may provide new tools for engineering glycoproteins of biotechnological interest.
TextSentencer_T5 709-854 Sentence denotes In the case of OTases involved in O-glycosylation (O-OTases), there is very low sequence homology between those from different bacterial species.
TextSentencer_T6 855-991 Sentence denotes The Wzy_C signature domain common to these enzymes is also present in WaaL ligases; enzymes involved in lipopolysaccharide biosynthesis.
TextSentencer_T7 992-1084 Sentence denotes Therefore, the identification of O-OTases using solely bioinformatic methods is problematic.
TextSentencer_T8 1085-1222 Sentence denotes The hypothetical proteins BTH_I0650 from Burkholderia thailandensis E264 and VC0393 from Vibrio cholerae N16961 contain the Wzy_C domain.
TextSentencer_T9 1223-1408 Sentence denotes In this work, we demonstrate that both proteins have O-OTase activity and renamed them PglL(Bt) and PglL(Vc), respectively, similar to the Neisseria meningitidis counterpart (PglL(Nm)).
TextSentencer_T10 1409-1490 Sentence denotes In E. coli, PglL(Bt) and PglL(Vc) display relaxed glycan and protein specificity.
TextSentencer_T11 1491-1613 Sentence denotes However, effective glycosylation depends upon a specific combination of the protein acceptor, glycan and O-OTase analyzed.
TextSentencer_T12 1614-1755 Sentence denotes This knowledge has important implications in the design of glycoconjugates and provides novel tools for use in glycoengineering applications.
TextSentencer_T13 1756-2008 Sentence denotes The codification of enzymatically active O-OTase in the genomes of members of the Vibrio and Burkholderia genera suggests the presence of still unknown O-glycoproteins in these organisms, which might have a role in bacterial physiology or pathogenesis.
T1 0-194 Sentence denotes Characterization of exogenous bacterial oligosaccharyltransferases in Escherichia coli reveals the potential for O-linked protein glycosylation in Vibrio cholerae and Burkholderia thailandensis.
T2 195-313 Sentence denotes Bacterial protein glycosylation systems from varying species have been functionally reconstituted in Escherichia coli.
T3 314-544 Sentence denotes Both N- and O-linked glycosylation pathways, in which the glycans are first assembled onto lipid carriers and subsequently transferred to acceptor proteins by an oligosaccharyltransferase (OTase), have been documented in bacteria.
T4 545-708 Sentence denotes The identification and characterization of novel OTases with different properties may provide new tools for engineering glycoproteins of biotechnological interest.
T5 709-854 Sentence denotes In the case of OTases involved in O-glycosylation (O-OTases), there is very low sequence homology between those from different bacterial species.
T6 855-991 Sentence denotes The Wzy_C signature domain common to these enzymes is also present in WaaL ligases; enzymes involved in lipopolysaccharide biosynthesis.
T7 992-1084 Sentence denotes Therefore, the identification of O-OTases using solely bioinformatic methods is problematic.
T8 1085-1222 Sentence denotes The hypothetical proteins BTH_I0650 from Burkholderia thailandensis E264 and VC0393 from Vibrio cholerae N16961 contain the Wzy_C domain.
T9 1223-1408 Sentence denotes In this work, we demonstrate that both proteins have O-OTase activity and renamed them PglL(Bt) and PglL(Vc), respectively, similar to the Neisseria meningitidis counterpart (PglL(Nm)).
T10 1409-1490 Sentence denotes In E. coli, PglL(Bt) and PglL(Vc) display relaxed glycan and protein specificity.
T11 1491-1613 Sentence denotes However, effective glycosylation depends upon a specific combination of the protein acceptor, glycan and O-OTase analyzed.
T12 1614-1755 Sentence denotes This knowledge has important implications in the design of glycoconjugates and provides novel tools for use in glycoengineering applications.
T13 1756-2008 Sentence denotes The codification of enzymatically active O-OTase in the genomes of members of the Vibrio and Burkholderia genera suggests the presence of still unknown O-glycoproteins in these organisms, which might have a role in bacterial physiology or pathogenesis.
T1 0-194 Sentence denotes Characterization of exogenous bacterial oligosaccharyltransferases in Escherichia coli reveals the potential for O-linked protein glycosylation in Vibrio cholerae and Burkholderia thailandensis.
T2 195-313 Sentence denotes Bacterial protein glycosylation systems from varying species have been functionally reconstituted in Escherichia coli.
T3 314-544 Sentence denotes Both N- and O-linked glycosylation pathways, in which the glycans are first assembled onto lipid carriers and subsequently transferred to acceptor proteins by an oligosaccharyltransferase (OTase), have been documented in bacteria.
T4 545-708 Sentence denotes The identification and characterization of novel OTases with different properties may provide new tools for engineering glycoproteins of biotechnological interest.
T5 709-854 Sentence denotes In the case of OTases involved in O-glycosylation (O-OTases), there is very low sequence homology between those from different bacterial species.
T6 855-991 Sentence denotes The Wzy_C signature domain common to these enzymes is also present in WaaL ligases; enzymes involved in lipopolysaccharide biosynthesis.
T7 992-1084 Sentence denotes Therefore, the identification of O-OTases using solely bioinformatic methods is problematic.
T8 1085-1222 Sentence denotes The hypothetical proteins BTH_I0650 from Burkholderia thailandensis E264 and VC0393 from Vibrio cholerae N16961 contain the Wzy_C domain.
T9 1223-1408 Sentence denotes In this work, we demonstrate that both proteins have O-OTase activity and renamed them PglL(Bt) and PglL(Vc), respectively, similar to the Neisseria meningitidis counterpart (PglL(Nm)).
T10 1409-1490 Sentence denotes In E. coli, PglL(Bt) and PglL(Vc) display relaxed glycan and protein specificity.
T11 1491-1613 Sentence denotes However, effective glycosylation depends upon a specific combination of the protein acceptor, glycan and O-OTase analyzed.
T12 1614-1755 Sentence denotes This knowledge has important implications in the design of glycoconjugates and provides novel tools for use in glycoengineering applications.
T13 1756-2008 Sentence denotes The codification of enzymatically active O-OTase in the genomes of members of the Vibrio and Burkholderia genera suggests the presence of still unknown O-glycoproteins in these organisms, which might have a role in bacterial physiology or pathogenesis.

GlycoBiology-GDGDB

Id Subject Object Predicate Lexical cue
_T1 1403-1405 http://acgg.asia/db/diseases/gdgdb?con_ui=CON00386 denotes Nm

GlycoBiology-PACDB

Id Subject Object Predicate Lexical cue
_T5 70-86 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC244,LEC256,LEC354 denotes Escherichia coli
_T6 70-86 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC636 denotes Escherichia coli
_T1 70-86 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC243,LEC640 denotes Escherichia coli
_T2 70-86 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC295,LEC417 denotes Escherichia coli
_T3 70-86 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC054,LEC058,LEC073,LEC082,LEC091,LEC103,LEC109,LEC110,LEC123,LEC158,LEC179,LEC198,LEC205,LEC222,LEC223,LEC224,LEC225,LEC232,LEC298,LEC357,LEC378,LEC383,LEC388,LEC389,LEC397,LEC401,LEC410,LEC452 denotes Escherichia coli
_T4 70-86 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC002,LEC056,LEC062,LEC069,LEC081,LEC111,LEC133,LEC171,LEC177,LEC187,LEC211,LEC242,LEC252,LEC258,LEC259,LEC260,LEC262,LEC369,LEC377,LEC422,LEC442,LEC448,LEC450,LEC451,LEC454,LEC472,LEC492,LEC620 denotes Escherichia coli
_T7 70-86 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC487 denotes Escherichia coli
_T8 70-86 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC754 denotes Escherichia coli
_T9 70-86 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC157,LEC407 denotes Escherichia coli
_T10 147-162 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC228,LEC233,LEC239,LEC279,LEC342,LEC505 denotes Vibrio cholerae
_T11 167-179 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC347 denotes Burkholderia
_T12 296-312 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC243,LEC640 denotes Escherichia coli
_T13 296-312 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC754 denotes Escherichia coli
_T14 296-312 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC157,LEC407 denotes Escherichia coli
_T15 296-312 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC487 denotes Escherichia coli
_T16 296-312 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC002,LEC056,LEC062,LEC069,LEC081,LEC111,LEC133,LEC171,LEC177,LEC187,LEC211,LEC242,LEC252,LEC258,LEC259,LEC260,LEC262,LEC369,LEC377,LEC422,LEC442,LEC448,LEC450,LEC451,LEC454,LEC472,LEC492,LEC620 denotes Escherichia coli
_T17 296-312 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC244,LEC256,LEC354 denotes Escherichia coli
_T18 296-312 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC636 denotes Escherichia coli
_T19 296-312 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC054,LEC058,LEC073,LEC082,LEC091,LEC103,LEC109,LEC110,LEC123,LEC158,LEC179,LEC198,LEC205,LEC222,LEC223,LEC224,LEC225,LEC232,LEC298,LEC357,LEC378,LEC383,LEC388,LEC389,LEC397,LEC401,LEC410,LEC452 denotes Escherichia coli
_T20 296-312 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC295,LEC417 denotes Escherichia coli
_T21 1126-1138 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC347 denotes Burkholderia
_T22 1174-1189 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC228,LEC233,LEC239,LEC279,LEC342,LEC505 denotes Vibrio cholerae
_T23 1362-1384 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC453,LEC742 denotes Neisseria meningitidis
_T24 1849-1861 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC347 denotes Burkholderia

ICD10

Id Subject Object Predicate Lexical cue
T1 154-162 http://purl.bioontology.org/ontology/ICD10/A00.9 denotes cholerae
T2 1181-1189 http://purl.bioontology.org/ontology/ICD10/A00.9 denotes cholerae
T3 154-162 http://purl.bioontology.org/ontology/ICD10/A00 denotes cholerae
T4 1181-1189 http://purl.bioontology.org/ontology/ICD10/A00 denotes cholerae

GlycoBiology-FMA

Id Subject Object Predicate Lexical cue
_T1 122-129 FMAID:67257 denotes protein
_T2 122-129 FMAID:165447 denotes protein
_T3 205-212 FMAID:67257 denotes protein
_T4 205-212 FMAID:165447 denotes protein
_T5 405-410 FMAID:165448 denotes lipid
_T6 405-410 FMAID:67264 denotes lipid
_T7 461-469 FMAID:165447 denotes proteins
_T8 461-469 FMAID:67257 denotes proteins
_T9 665-678 FMAID:62925 denotes glycoproteins
_T10 665-678 FMAID:167256 denotes glycoproteins
_T11 959-977 FMAID:82746 denotes lipopolysaccharide
_T12 959-977 FMAID:196779 denotes lipopolysaccharide
_T13 959-977 FMAID:82785 denotes lipopolysaccharide
_T14 959-977 FMAID:196735 denotes lipopolysaccharide
_T15 1040-1046 FMAID:117624 denotes solely
_T16 1102-1110 FMAID:165447 denotes proteins
_T17 1102-1110 FMAID:67257 denotes proteins
_T18 1262-1270 FMAID:165447 denotes proteins
_T19 1262-1270 FMAID:67257 denotes proteins
_T20 1470-1477 FMAID:67257 denotes protein
_T21 1470-1477 FMAID:165447 denotes protein
_T22 1567-1574 FMAID:67257 denotes protein
_T23 1567-1574 FMAID:165447 denotes protein
_T24 1673-1688 FMAID:82782 denotes glycoconjugates
_T25 1673-1688 FMAID:196776 denotes glycoconjugates
_T26 1812-1819 FMAID:84116 denotes genomes
_T27 1812-1819 FMAID:198062 denotes genomes
_T28 1910-1923 FMAID:62925 denotes glycoproteins
_T29 1910-1923 FMAID:167256 denotes glycoproteins
_T30 1933-1942 FMAID:166081 denotes organisms
_T31 1933-1942 FMAID:67498 denotes organisms

uniprot-human

Id Subject Object Predicate Lexical cue
T1 503-508 http://www.uniprot.org/uniprot/Q9UIQ6 denotes OTase
T2 1278-1283 http://www.uniprot.org/uniprot/Q9UIQ6 denotes OTase
T3 1598-1603 http://www.uniprot.org/uniprot/Q9UIQ6 denotes OTase
T4 1799-1804 http://www.uniprot.org/uniprot/Q9UIQ6 denotes OTase

uniprot-mouse

Id Subject Object Predicate Lexical cue
T1 503-508 http://www.uniprot.org/uniprot/Q8C129 denotes OTase
T2 1278-1283 http://www.uniprot.org/uniprot/Q8C129 denotes OTase
T3 1598-1603 http://www.uniprot.org/uniprot/Q8C129 denotes OTase
T4 1799-1804 http://www.uniprot.org/uniprot/Q8C129 denotes OTase

GlycoBiology-NCBITAXON

Id Subject Object Predicate Lexical cue
T1 70-81 http://purl.bioontology.org/ontology/NCBITAXON/561 denotes Escherichia
T2 147-162 http://purl.bioontology.org/ontology/NCBITAXON/650003 denotes Vibrio cholerae
T3 147-162 http://purl.bioontology.org/ontology/NCBITAXON/666 denotes Vibrio cholerae
T4 167-179 http://purl.bioontology.org/ontology/NCBITAXON/219649 denotes Burkholderia
T5 167-179 http://purl.bioontology.org/ontology/NCBITAXON/634127 denotes Burkholderia
T6 167-179 http://purl.bioontology.org/ontology/NCBITAXON/292 denotes Burkholderia
T7 167-179 http://purl.bioontology.org/ontology/NCBITAXON/948107 denotes Burkholderia
T8 167-179 http://purl.bioontology.org/ontology/NCBITAXON/32008 denotes Burkholderia
T9 167-179 http://purl.bioontology.org/ontology/NCBITAXON/386056 denotes Burkholderia
T10 167-179 http://purl.bioontology.org/ontology/NCBITAXON/482957 denotes Burkholderia
T11 167-179 http://purl.bioontology.org/ontology/NCBITAXON/311230 denotes Burkholderia
T12 167-179 http://purl.bioontology.org/ontology/NCBITAXON/337 denotes Burkholderia
T13 167-193 http://purl.bioontology.org/ontology/NCBITAXON/57975 denotes Burkholderia thailandensis
T14 296-307 http://purl.bioontology.org/ontology/NCBITAXON/561 denotes Escherichia
T15 535-543 http://purl.bioontology.org/ontology/NCBITAXON/2 denotes bacteria
T16 535-543 http://purl.bioontology.org/ontology/NCBITAXON/629395 denotes bacteria
T17 1126-1138 http://purl.bioontology.org/ontology/NCBITAXON/948107 denotes Burkholderia
T18 1126-1138 http://purl.bioontology.org/ontology/NCBITAXON/337 denotes Burkholderia
T19 1126-1138 http://purl.bioontology.org/ontology/NCBITAXON/482957 denotes Burkholderia
T20 1126-1138 http://purl.bioontology.org/ontology/NCBITAXON/386056 denotes Burkholderia
T21 1126-1138 http://purl.bioontology.org/ontology/NCBITAXON/32008 denotes Burkholderia
T22 1126-1138 http://purl.bioontology.org/ontology/NCBITAXON/634127 denotes Burkholderia
T23 1126-1138 http://purl.bioontology.org/ontology/NCBITAXON/311230 denotes Burkholderia
T24 1126-1138 http://purl.bioontology.org/ontology/NCBITAXON/219649 denotes Burkholderia
T25 1126-1138 http://purl.bioontology.org/ontology/NCBITAXON/292 denotes Burkholderia
T26 1126-1152 http://purl.bioontology.org/ontology/NCBITAXON/57975 denotes Burkholderia thailandensis
T27 1174-1189 http://purl.bioontology.org/ontology/NCBITAXON/666 denotes Vibrio cholerae
T28 1174-1189 http://purl.bioontology.org/ontology/NCBITAXON/650003 denotes Vibrio cholerae
T29 1362-1371 http://purl.bioontology.org/ontology/NCBITAXON/482 denotes Neisseria
T30 1362-1371 http://purl.bioontology.org/ontology/NCBITAXON/206351 denotes Neisseria
T31 1362-1371 http://purl.bioontology.org/ontology/NCBITAXON/481 denotes Neisseria
T32 1362-1384 http://purl.bioontology.org/ontology/NCBITAXON/487 denotes Neisseria meningitidis
T33 1849-1861 http://purl.bioontology.org/ontology/NCBITAXON/311230 denotes Burkholderia
T34 1849-1861 http://purl.bioontology.org/ontology/NCBITAXON/948107 denotes Burkholderia
T35 1849-1861 http://purl.bioontology.org/ontology/NCBITAXON/32008 denotes Burkholderia
T36 1849-1861 http://purl.bioontology.org/ontology/NCBITAXON/219649 denotes Burkholderia
T37 1849-1861 http://purl.bioontology.org/ontology/NCBITAXON/386056 denotes Burkholderia
T38 1849-1861 http://purl.bioontology.org/ontology/NCBITAXON/337 denotes Burkholderia
T39 1849-1861 http://purl.bioontology.org/ontology/NCBITAXON/482957 denotes Burkholderia
T40 1849-1861 http://purl.bioontology.org/ontology/NCBITAXON/634127 denotes Burkholderia
T41 1849-1861 http://purl.bioontology.org/ontology/NCBITAXON/292 denotes Burkholderia

GO-BP

Id Subject Object Predicate Lexical cue
T1 20-29 http://purl.obolibrary.org/obo/GO_0042638 denotes exogenous
T2 122-143 http://purl.obolibrary.org/obo/GO_0006486 denotes protein glycosylation
T3 205-226 http://purl.obolibrary.org/obo/GO_0006486 denotes protein glycosylation
T4 130-143 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation
T5 213-226 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation
T6 335-348 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation
T7 745-758 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation
T8 1510-1523 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation
T9 326-348 http://purl.obolibrary.org/obo/GO_0006493 denotes O-linked glycosylation
T10 959-990 http://purl.obolibrary.org/obo/GO_0009103 denotes lipopolysaccharide biosynthesis
T11 978-990 http://purl.obolibrary.org/obo/GO_0009058 denotes biosynthesis
T12 1995-2007 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis

UBERON-AE

Id Subject Object Predicate Lexical cue
T1 1933-1942 http://purl.obolibrary.org/obo/UBERON_0000062 denotes organisms

Allie

Id Subject Object Predicate Lexical cue
SS1_22391990_2_0 476-501 expanded denotes oligosaccharyltransferase
SS2_22391990_2_0 503-508 abbr denotes OTase
AE1_22391990_2_0 SS1_22391990_2_0 SS2_22391990_2_0 abbreviatedTo oligosaccharyltransferase,OTase

performance-test

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 1933-1942 http://purl.obolibrary.org/obo/UBERON_0000062 denotes organisms

mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 147-162 Disease denotes Vibrio cholerae http://purl.obolibrary.org/obo/MONDO_0015766
T2 1174-1189 Disease denotes Vibrio cholerae http://purl.obolibrary.org/obo/MONDO_0015766

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 70-86 OrganismTaxon denotes Escherichia coli 562
T2 147-162 OrganismTaxon denotes Vibrio cholerae 666
T3 167-193 OrganismTaxon denotes Burkholderia thailandensis 57975
T4 296-312 OrganismTaxon denotes Escherichia coli 562
T5 535-543 OrganismTaxon denotes bacteria 2|629395
T7 1126-1152 OrganismTaxon denotes Burkholderia thailandensis 57975
T8 1174-1189 OrganismTaxon denotes Vibrio cholerae 666
T9 1362-1384 OrganismTaxon denotes Neisseria meningitidis 487
T10 1412-1419 OrganismTaxon denotes E. coli 562
T11 1838-1844 OrganismTaxon denotes Vibrio 662
T12 1849-1861 OrganismTaxon denotes Burkholderia 32008

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 1933-1942 Body_part denotes organisms http://purl.obolibrary.org/obo/UBERON_0000468