PubMed:22330637
Annnotations
Inflammaging
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-102 | Sentence | denotes | Increased hepatic expression of TLR2 and TLR4 in the hepatic inflammation-fibrosis-carcinoma sequence. |
T2 | 103-274 | Sentence | denotes | We evaluated expression of TLR2, TLR4 and proinflammatory genes [NF-κB, TNF-α, cyclooxygenase-2 (COX-2)] in liver samples of patients in different stages of liver disease. |
T3 | 275-562 | Sentence | denotes | Fifteen patients with unexplained transaminases elevation (reference group), 22 with viral chronic hepatitis (hepatitis group), 14 with virus-induced severe fibrosis/cirrhosis (cirrhosis group) and 10 with hepatocarcinoma (hepatocarcinoma group) were consecutively included in the study. |
T4 | 563-725 | Sentence | denotes | Quantification of TLR2, TLR4, NF-κB, TNF-α and COX-2 mRNA was done by real-time RT-PCR and TLR2 and TLR4 protein expression was evaluated by immunohistochemistry. |
T5 | 726-803 | Sentence | denotes | Compared with reference, TLR2 and TLR4 mRNA was increased in hepatitis (TLR2: |
T6 | 804-822 | Sentence | denotes | 2.66 ± 0.69; TLR4: |
T7 | 823-866 | Sentence | denotes | 3.11 ± 0.79; P < 0.05) and cirrhosis (TLR2: |
T8 | 867-884 | Sentence | denotes | 2.14 ± 0.5; TLR4: |
T9 | 885-947 | Sentence | denotes | 1.74 ± 0.27; P < 0.05) and decreased in hepatocarcinoma (TLR2: |
T10 | 948-966 | Sentence | denotes | 0.48 ± 0.15; TLR4: |
T11 | 967-990 | Sentence | denotes | 0.54 ± 0.10; P < 0.05). |
T12 | 991-1063 | Sentence | denotes | This associated with increased TNF-α and COX-2 mRNA in hepatitis (TNF-α: |
T13 | 1064-1083 | Sentence | denotes | 3.24 ± 0.79; COX-2: |
T14 | 1084-1128 | Sentence | denotes | 2.47 ± 0.36; P < 0.05) and cirrhosis (TNF-α: |
T15 | 1129-1148 | Sentence | denotes | 1.73 ± 0.28; COX-2: |
T16 | 1149-1292 | Sentence | denotes | 1.8 ± 0.35, P < 0.05), whereas NF-κB mRNA was increased in hepatitis (2.42 ± 0.31; P < 0.05) and unchanged in cirrhosis (1.34 ± 0.17; P = 0.3). |
T17 | 1293-1474 | Sentence | denotes | Hepatocarcinoma presented increased COX-2 mRNA (1.63 ± 0.15; P < 0.05) and maintained (at decreased levels) mRNA of NF-κB (0.52 ± 0.12) and TNF-α (0.52 ± 0.12; P < 0.05, all genes). |
T18 | 1475-1616 | Sentence | denotes | Immunohistochemistry confirmed increased expression of TLR2 and TLR4 in hepatitis and cirrhosis and maintained expression in hepatocarcinoma. |
T19 | 1617-1734 | Sentence | denotes | Upregulation of TLR2, TLR4 and their proinflammatory mediators is associated with virus-induced hepatic IFC sequence. |
T1 | 0-102 | Sentence | denotes | Increased hepatic expression of TLR2 and TLR4 in the hepatic inflammation-fibrosis-carcinoma sequence. |
T2 | 103-274 | Sentence | denotes | We evaluated expression of TLR2, TLR4 and proinflammatory genes [NF-κB, TNF-α, cyclooxygenase-2 (COX-2)] in liver samples of patients in different stages of liver disease. |
T3 | 275-562 | Sentence | denotes | Fifteen patients with unexplained transaminases elevation (reference group), 22 with viral chronic hepatitis (hepatitis group), 14 with virus-induced severe fibrosis/cirrhosis (cirrhosis group) and 10 with hepatocarcinoma (hepatocarcinoma group) were consecutively included in the study. |
T4 | 563-725 | Sentence | denotes | Quantification of TLR2, TLR4, NF-κB, TNF-α and COX-2 mRNA was done by real-time RT-PCR and TLR2 and TLR4 protein expression was evaluated by immunohistochemistry. |
T5 | 726-803 | Sentence | denotes | Compared with reference, TLR2 and TLR4 mRNA was increased in hepatitis (TLR2: |
T6 | 804-822 | Sentence | denotes | 2.66 ± 0.69; TLR4: |
T7 | 823-866 | Sentence | denotes | 3.11 ± 0.79; P < 0.05) and cirrhosis (TLR2: |
T8 | 867-884 | Sentence | denotes | 2.14 ± 0.5; TLR4: |
T9 | 885-947 | Sentence | denotes | 1.74 ± 0.27; P < 0.05) and decreased in hepatocarcinoma (TLR2: |
T10 | 948-966 | Sentence | denotes | 0.48 ± 0.15; TLR4: |
T11 | 967-990 | Sentence | denotes | 0.54 ± 0.10; P < 0.05). |
T12 | 991-1063 | Sentence | denotes | This associated with increased TNF-α and COX-2 mRNA in hepatitis (TNF-α: |
T13 | 1064-1083 | Sentence | denotes | 3.24 ± 0.79; COX-2: |
T14 | 1084-1128 | Sentence | denotes | 2.47 ± 0.36; P < 0.05) and cirrhosis (TNF-α: |
T15 | 1129-1148 | Sentence | denotes | 1.73 ± 0.28; COX-2: |
T16 | 1149-1292 | Sentence | denotes | 1.8 ± 0.35, P < 0.05), whereas NF-κB mRNA was increased in hepatitis (2.42 ± 0.31; P < 0.05) and unchanged in cirrhosis (1.34 ± 0.17; P = 0.3). |
T17 | 1293-1474 | Sentence | denotes | Hepatocarcinoma presented increased COX-2 mRNA (1.63 ± 0.15; P < 0.05) and maintained (at decreased levels) mRNA of NF-κB (0.52 ± 0.12) and TNF-α (0.52 ± 0.12; P < 0.05, all genes). |
T18 | 1475-1616 | Sentence | denotes | Immunohistochemistry confirmed increased expression of TLR2 and TLR4 in hepatitis and cirrhosis and maintained expression in hepatocarcinoma. |
T19 | 1617-1734 | Sentence | denotes | Upregulation of TLR2, TLR4 and their proinflammatory mediators is associated with virus-induced hepatic IFC sequence. |
DisGeNET
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T0 | 41-45 | gene:7099 | denotes | TLR4 |
T1 | 83-92 | disease:C0007097 | denotes | carcinoma |
T2 | 32-36 | gene:7097 | denotes | TLR2 |
T3 | 83-92 | disease:C0007097 | denotes | carcinoma |
T4 | 200-205 | gene:5743 | denotes | COX-2 |
T5 | 260-273 | disease:C0023895 | denotes | liver disease |
T6 | 182-198 | gene:5743 | denotes | cyclooxygenase-2 |
T7 | 260-273 | disease:C0023895 | denotes | liver disease |
T8 | 175-180 | gene:7124 | denotes | TNF-α |
T9 | 260-273 | disease:C0023895 | denotes | liver disease |
T10 | 136-140 | gene:7099 | denotes | TLR4 |
T11 | 260-273 | disease:C0023895 | denotes | liver disease |
T12 | 130-134 | gene:7097 | denotes | TLR2 |
T13 | 260-273 | disease:C0023895 | denotes | liver disease |
T14 | 961-965 | gene:7099 | denotes | TLR4 |
T15 | 925-940 | disease:C2239176 | denotes | hepatocarcinoma |
T16 | 961-965 | gene:7099 | denotes | TLR4 |
T17 | 850-859 | disease:C1623038 | denotes | cirrhosis |
T18 | 961-965 | gene:7099 | denotes | TLR4 |
T19 | 850-859 | disease:C0023890 | denotes | cirrhosis |
T20 | 961-965 | gene:7099 | denotes | TLR4 |
T21 | 787-796 | disease:C0019159 | denotes | hepatitis |
T22 | 961-965 | gene:7099 | denotes | TLR4 |
T23 | 787-796 | disease:C0019158 | denotes | hepatitis |
T24 | 942-946 | gene:7097 | denotes | TLR2 |
T25 | 925-940 | disease:C2239176 | denotes | hepatocarcinoma |
T26 | 942-946 | gene:7097 | denotes | TLR2 |
T27 | 850-859 | disease:C1623038 | denotes | cirrhosis |
T28 | 942-946 | gene:7097 | denotes | TLR2 |
T29 | 850-859 | disease:C0023890 | denotes | cirrhosis |
T30 | 942-946 | gene:7097 | denotes | TLR2 |
T31 | 787-796 | disease:C0019159 | denotes | hepatitis |
T32 | 942-946 | gene:7097 | denotes | TLR2 |
T33 | 787-796 | disease:C0019158 | denotes | hepatitis |
T34 | 879-883 | gene:7099 | denotes | TLR4 |
T35 | 925-940 | disease:C2239176 | denotes | hepatocarcinoma |
T36 | 879-883 | gene:7099 | denotes | TLR4 |
T37 | 850-859 | disease:C1623038 | denotes | cirrhosis |
T38 | 879-883 | gene:7099 | denotes | TLR4 |
T39 | 850-859 | disease:C0023890 | denotes | cirrhosis |
T40 | 879-883 | gene:7099 | denotes | TLR4 |
T41 | 787-796 | disease:C0019159 | denotes | hepatitis |
T42 | 879-883 | gene:7099 | denotes | TLR4 |
T43 | 787-796 | disease:C0019158 | denotes | hepatitis |
T44 | 861-865 | gene:7097 | denotes | TLR2 |
T45 | 925-940 | disease:C2239176 | denotes | hepatocarcinoma |
T46 | 861-865 | gene:7097 | denotes | TLR2 |
T47 | 850-859 | disease:C1623038 | denotes | cirrhosis |
T48 | 861-865 | gene:7097 | denotes | TLR2 |
T49 | 850-859 | disease:C0023890 | denotes | cirrhosis |
T50 | 861-865 | gene:7097 | denotes | TLR2 |
T51 | 787-796 | disease:C0019159 | denotes | hepatitis |
T52 | 861-865 | gene:7097 | denotes | TLR2 |
T53 | 787-796 | disease:C0019158 | denotes | hepatitis |
T54 | 817-821 | gene:7099 | denotes | TLR4 |
T55 | 925-940 | disease:C2239176 | denotes | hepatocarcinoma |
T56 | 817-821 | gene:7099 | denotes | TLR4 |
T57 | 850-859 | disease:C1623038 | denotes | cirrhosis |
T58 | 817-821 | gene:7099 | denotes | TLR4 |
T59 | 850-859 | disease:C0023890 | denotes | cirrhosis |
T60 | 817-821 | gene:7099 | denotes | TLR4 |
T61 | 787-796 | disease:C0019159 | denotes | hepatitis |
T62 | 817-821 | gene:7099 | denotes | TLR4 |
T63 | 787-796 | disease:C0019158 | denotes | hepatitis |
T64 | 798-802 | gene:7097 | denotes | TLR2 |
T65 | 925-940 | disease:C2239176 | denotes | hepatocarcinoma |
T66 | 798-802 | gene:7097 | denotes | TLR2 |
T67 | 850-859 | disease:C1623038 | denotes | cirrhosis |
T68 | 798-802 | gene:7097 | denotes | TLR2 |
T69 | 850-859 | disease:C0023890 | denotes | cirrhosis |
T70 | 798-802 | gene:7097 | denotes | TLR2 |
T71 | 787-796 | disease:C0019159 | denotes | hepatitis |
T72 | 798-802 | gene:7097 | denotes | TLR2 |
T73 | 787-796 | disease:C0019158 | denotes | hepatitis |
T74 | 760-764 | gene:7099 | denotes | TLR4 |
T75 | 925-940 | disease:C2239176 | denotes | hepatocarcinoma |
T76 | 760-764 | gene:7099 | denotes | TLR4 |
T77 | 850-859 | disease:C1623038 | denotes | cirrhosis |
T78 | 760-764 | gene:7099 | denotes | TLR4 |
T79 | 850-859 | disease:C0023890 | denotes | cirrhosis |
T80 | 760-764 | gene:7099 | denotes | TLR4 |
T81 | 787-796 | disease:C0019159 | denotes | hepatitis |
T82 | 760-764 | gene:7099 | denotes | TLR4 |
T83 | 787-796 | disease:C0019158 | denotes | hepatitis |
T84 | 751-755 | gene:7097 | denotes | TLR2 |
T85 | 925-940 | disease:C2239176 | denotes | hepatocarcinoma |
T86 | 751-755 | gene:7097 | denotes | TLR2 |
T87 | 850-859 | disease:C1623038 | denotes | cirrhosis |
T88 | 751-755 | gene:7097 | denotes | TLR2 |
T89 | 850-859 | disease:C0023890 | denotes | cirrhosis |
T90 | 751-755 | gene:7097 | denotes | TLR2 |
T91 | 787-796 | disease:C0019159 | denotes | hepatitis |
T92 | 751-755 | gene:7097 | denotes | TLR2 |
T93 | 787-796 | disease:C0019158 | denotes | hepatitis |
T94 | 1180-1185 | gene:4790 | denotes | NF-κB |
T95 | 1259-1268 | disease:C1623038 | denotes | cirrhosis |
T96 | 1180-1185 | gene:4790 | denotes | NF-κB |
T97 | 1259-1268 | disease:C0023890 | denotes | cirrhosis |
T98 | 1180-1185 | gene:4790 | denotes | NF-κB |
T99 | 1208-1217 | disease:C0019159 | denotes | hepatitis |
T100 | 1180-1185 | gene:4790 | denotes | NF-κB |
T101 | 1208-1217 | disease:C0019158 | denotes | hepatitis |
T102 | 1180-1185 | gene:4790 | denotes | NF-κB |
T103 | 1111-1120 | disease:C1623038 | denotes | cirrhosis |
T104 | 1180-1185 | gene:4790 | denotes | NF-κB |
T105 | 1111-1120 | disease:C0023890 | denotes | cirrhosis |
T106 | 1180-1185 | gene:4790 | denotes | NF-κB |
T107 | 1046-1055 | disease:C0019159 | denotes | hepatitis |
T108 | 1180-1185 | gene:4790 | denotes | NF-κB |
T109 | 1046-1055 | disease:C0019158 | denotes | hepatitis |
T110 | 1142-1147 | gene:5743 | denotes | COX-2 |
T111 | 1259-1268 | disease:C1623038 | denotes | cirrhosis |
T112 | 1142-1147 | gene:5743 | denotes | COX-2 |
T113 | 1259-1268 | disease:C0023890 | denotes | cirrhosis |
T114 | 1142-1147 | gene:5743 | denotes | COX-2 |
T115 | 1208-1217 | disease:C0019159 | denotes | hepatitis |
T116 | 1142-1147 | gene:5743 | denotes | COX-2 |
T117 | 1208-1217 | disease:C0019158 | denotes | hepatitis |
T118 | 1142-1147 | gene:5743 | denotes | COX-2 |
T119 | 1111-1120 | disease:C1623038 | denotes | cirrhosis |
T120 | 1142-1147 | gene:5743 | denotes | COX-2 |
T121 | 1111-1120 | disease:C0023890 | denotes | cirrhosis |
T122 | 1142-1147 | gene:5743 | denotes | COX-2 |
T123 | 1046-1055 | disease:C0019159 | denotes | hepatitis |
T124 | 1142-1147 | gene:5743 | denotes | COX-2 |
T125 | 1046-1055 | disease:C0019158 | denotes | hepatitis |
T126 | 1122-1127 | gene:7124 | denotes | TNF-α |
T127 | 1259-1268 | disease:C1623038 | denotes | cirrhosis |
T128 | 1122-1127 | gene:7124 | denotes | TNF-α |
T129 | 1259-1268 | disease:C0023890 | denotes | cirrhosis |
T130 | 1122-1127 | gene:7124 | denotes | TNF-α |
T131 | 1208-1217 | disease:C0019159 | denotes | hepatitis |
T132 | 1122-1127 | gene:7124 | denotes | TNF-α |
T133 | 1208-1217 | disease:C0019158 | denotes | hepatitis |
T134 | 1122-1127 | gene:7124 | denotes | TNF-α |
T135 | 1111-1120 | disease:C1623038 | denotes | cirrhosis |
T136 | 1122-1127 | gene:7124 | denotes | TNF-α |
T137 | 1111-1120 | disease:C0023890 | denotes | cirrhosis |
T138 | 1122-1127 | gene:7124 | denotes | TNF-α |
T139 | 1046-1055 | disease:C0019159 | denotes | hepatitis |
T140 | 1122-1127 | gene:7124 | denotes | TNF-α |
T141 | 1046-1055 | disease:C0019158 | denotes | hepatitis |
T142 | 1077-1082 | gene:5743 | denotes | COX-2 |
T143 | 1259-1268 | disease:C1623038 | denotes | cirrhosis |
T144 | 1077-1082 | gene:5743 | denotes | COX-2 |
T145 | 1259-1268 | disease:C0023890 | denotes | cirrhosis |
T146 | 1077-1082 | gene:5743 | denotes | COX-2 |
T147 | 1208-1217 | disease:C0019159 | denotes | hepatitis |
T148 | 1077-1082 | gene:5743 | denotes | COX-2 |
T149 | 1208-1217 | disease:C0019158 | denotes | hepatitis |
T150 | 1077-1082 | gene:5743 | denotes | COX-2 |
T151 | 1111-1120 | disease:C1623038 | denotes | cirrhosis |
T152 | 1077-1082 | gene:5743 | denotes | COX-2 |
T153 | 1111-1120 | disease:C0023890 | denotes | cirrhosis |
T154 | 1077-1082 | gene:5743 | denotes | COX-2 |
T155 | 1046-1055 | disease:C0019159 | denotes | hepatitis |
T156 | 1077-1082 | gene:5743 | denotes | COX-2 |
T157 | 1046-1055 | disease:C0019158 | denotes | hepatitis |
T158 | 1057-1062 | gene:7124 | denotes | TNF-α |
T159 | 1259-1268 | disease:C1623038 | denotes | cirrhosis |
T160 | 1057-1062 | gene:7124 | denotes | TNF-α |
T161 | 1259-1268 | disease:C0023890 | denotes | cirrhosis |
T162 | 1057-1062 | gene:7124 | denotes | TNF-α |
T163 | 1208-1217 | disease:C0019159 | denotes | hepatitis |
T164 | 1057-1062 | gene:7124 | denotes | TNF-α |
T165 | 1208-1217 | disease:C0019158 | denotes | hepatitis |
T166 | 1057-1062 | gene:7124 | denotes | TNF-α |
T167 | 1111-1120 | disease:C1623038 | denotes | cirrhosis |
T168 | 1057-1062 | gene:7124 | denotes | TNF-α |
T169 | 1111-1120 | disease:C0023890 | denotes | cirrhosis |
T170 | 1057-1062 | gene:7124 | denotes | TNF-α |
T171 | 1046-1055 | disease:C0019159 | denotes | hepatitis |
T172 | 1057-1062 | gene:7124 | denotes | TNF-α |
T173 | 1046-1055 | disease:C0019158 | denotes | hepatitis |
T174 | 1032-1037 | gene:5743 | denotes | COX-2 |
T175 | 1259-1268 | disease:C1623038 | denotes | cirrhosis |
T176 | 1032-1037 | gene:5743 | denotes | COX-2 |
T177 | 1259-1268 | disease:C0023890 | denotes | cirrhosis |
T178 | 1032-1037 | gene:5743 | denotes | COX-2 |
T179 | 1208-1217 | disease:C0019159 | denotes | hepatitis |
T180 | 1032-1037 | gene:5743 | denotes | COX-2 |
T181 | 1208-1217 | disease:C0019158 | denotes | hepatitis |
T182 | 1032-1037 | gene:5743 | denotes | COX-2 |
T183 | 1111-1120 | disease:C1623038 | denotes | cirrhosis |
T184 | 1032-1037 | gene:5743 | denotes | COX-2 |
T185 | 1111-1120 | disease:C0023890 | denotes | cirrhosis |
T186 | 1032-1037 | gene:5743 | denotes | COX-2 |
T187 | 1046-1055 | disease:C0019159 | denotes | hepatitis |
T188 | 1032-1037 | gene:5743 | denotes | COX-2 |
T189 | 1046-1055 | disease:C0019158 | denotes | hepatitis |
T190 | 1022-1027 | gene:7124 | denotes | TNF-α |
T191 | 1259-1268 | disease:C1623038 | denotes | cirrhosis |
T192 | 1022-1027 | gene:7124 | denotes | TNF-α |
T193 | 1259-1268 | disease:C0023890 | denotes | cirrhosis |
T194 | 1022-1027 | gene:7124 | denotes | TNF-α |
T195 | 1208-1217 | disease:C0019159 | denotes | hepatitis |
T196 | 1022-1027 | gene:7124 | denotes | TNF-α |
T197 | 1208-1217 | disease:C0019158 | denotes | hepatitis |
T198 | 1022-1027 | gene:7124 | denotes | TNF-α |
T199 | 1111-1120 | disease:C1623038 | denotes | cirrhosis |
T200 | 1022-1027 | gene:7124 | denotes | TNF-α |
T201 | 1111-1120 | disease:C0023890 | denotes | cirrhosis |
T202 | 1022-1027 | gene:7124 | denotes | TNF-α |
T203 | 1046-1055 | disease:C0019159 | denotes | hepatitis |
T204 | 1022-1027 | gene:7124 | denotes | TNF-α |
T205 | 1046-1055 | disease:C0019158 | denotes | hepatitis |
T206 | 1433-1438 | gene:7124 | denotes | TNF-α |
T207 | 1293-1308 | disease:C2239176 | denotes | Hepatocarcinoma |
T208 | 1409-1414 | gene:4790 | denotes | NF-κB |
T209 | 1293-1308 | disease:C2239176 | denotes | Hepatocarcinoma |
T210 | 1329-1334 | gene:5743 | denotes | COX-2 |
T211 | 1293-1308 | disease:C2239176 | denotes | Hepatocarcinoma |
T212 | 1539-1543 | gene:7099 | denotes | TLR4 |
T213 | 1600-1615 | disease:C2239176 | denotes | hepatocarcinoma |
T214 | 1539-1543 | gene:7099 | denotes | TLR4 |
T215 | 1561-1570 | disease:C1623038 | denotes | cirrhosis |
T216 | 1539-1543 | gene:7099 | denotes | TLR4 |
T217 | 1561-1570 | disease:C0023890 | denotes | cirrhosis |
T218 | 1539-1543 | gene:7099 | denotes | TLR4 |
T219 | 1547-1556 | disease:C0019159 | denotes | hepatitis |
T220 | 1539-1543 | gene:7099 | denotes | TLR4 |
T221 | 1547-1556 | disease:C0019158 | denotes | hepatitis |
T222 | 1530-1534 | gene:7097 | denotes | TLR2 |
T223 | 1600-1615 | disease:C2239176 | denotes | hepatocarcinoma |
T224 | 1530-1534 | gene:7097 | denotes | TLR2 |
T225 | 1561-1570 | disease:C1623038 | denotes | cirrhosis |
T226 | 1530-1534 | gene:7097 | denotes | TLR2 |
T227 | 1561-1570 | disease:C0023890 | denotes | cirrhosis |
T228 | 1530-1534 | gene:7097 | denotes | TLR2 |
T229 | 1547-1556 | disease:C0019159 | denotes | hepatitis |
T230 | 1530-1534 | gene:7097 | denotes | TLR2 |
T231 | 1547-1556 | disease:C0019158 | denotes | hepatitis |
R1 | T0 | T1 | associated_with | TLR4,carcinoma |
R2 | T2 | T3 | associated_with | TLR2,carcinoma |
R3 | T4 | T5 | associated_with | COX-2,liver disease |
R4 | T6 | T7 | associated_with | cyclooxygenase-2,liver disease |
R5 | T8 | T9 | associated_with | TNF-α,liver disease |
R6 | T10 | T11 | associated_with | TLR4,liver disease |
R7 | T12 | T13 | associated_with | TLR2,liver disease |
R8 | T14 | T15 | associated_with | TLR4,hepatocarcinoma |
R9 | T16 | T17 | associated_with | TLR4,cirrhosis |
R10 | T18 | T19 | associated_with | TLR4,cirrhosis |
R11 | T20 | T21 | associated_with | TLR4,hepatitis |
R12 | T22 | T23 | associated_with | TLR4,hepatitis |
R13 | T24 | T25 | associated_with | TLR2,hepatocarcinoma |
R14 | T26 | T27 | associated_with | TLR2,cirrhosis |
R15 | T28 | T29 | associated_with | TLR2,cirrhosis |
R16 | T30 | T31 | associated_with | TLR2,hepatitis |
R17 | T32 | T33 | associated_with | TLR2,hepatitis |
R18 | T34 | T35 | associated_with | TLR4,hepatocarcinoma |
R19 | T36 | T37 | associated_with | TLR4,cirrhosis |
R20 | T38 | T39 | associated_with | TLR4,cirrhosis |
R21 | T40 | T41 | associated_with | TLR4,hepatitis |
R22 | T42 | T43 | associated_with | TLR4,hepatitis |
R23 | T44 | T45 | associated_with | TLR2,hepatocarcinoma |
R24 | T46 | T47 | associated_with | TLR2,cirrhosis |
R25 | T48 | T49 | associated_with | TLR2,cirrhosis |
R26 | T50 | T51 | associated_with | TLR2,hepatitis |
R27 | T52 | T53 | associated_with | TLR2,hepatitis |
R28 | T54 | T55 | associated_with | TLR4,hepatocarcinoma |
R29 | T56 | T57 | associated_with | TLR4,cirrhosis |
R30 | T58 | T59 | associated_with | TLR4,cirrhosis |
R31 | T60 | T61 | associated_with | TLR4,hepatitis |
R32 | T62 | T63 | associated_with | TLR4,hepatitis |
R33 | T64 | T65 | associated_with | TLR2,hepatocarcinoma |
R34 | T66 | T67 | associated_with | TLR2,cirrhosis |
R35 | T68 | T69 | associated_with | TLR2,cirrhosis |
R36 | T70 | T71 | associated_with | TLR2,hepatitis |
R37 | T72 | T73 | associated_with | TLR2,hepatitis |
R38 | T74 | T75 | associated_with | TLR4,hepatocarcinoma |
R39 | T76 | T77 | associated_with | TLR4,cirrhosis |
R40 | T78 | T79 | associated_with | TLR4,cirrhosis |
R41 | T80 | T81 | associated_with | TLR4,hepatitis |
R42 | T82 | T83 | associated_with | TLR4,hepatitis |
R43 | T84 | T85 | associated_with | TLR2,hepatocarcinoma |
R44 | T86 | T87 | associated_with | TLR2,cirrhosis |
R45 | T88 | T89 | associated_with | TLR2,cirrhosis |
R46 | T90 | T91 | associated_with | TLR2,hepatitis |
R47 | T92 | T93 | associated_with | TLR2,hepatitis |
R48 | T94 | T95 | associated_with | NF-κB,cirrhosis |
R49 | T96 | T97 | associated_with | NF-κB,cirrhosis |
R50 | T98 | T99 | associated_with | NF-κB,hepatitis |
R51 | T100 | T101 | associated_with | NF-κB,hepatitis |
R52 | T102 | T103 | associated_with | NF-κB,cirrhosis |
R53 | T104 | T105 | associated_with | NF-κB,cirrhosis |
R54 | T106 | T107 | associated_with | NF-κB,hepatitis |
R55 | T108 | T109 | associated_with | NF-κB,hepatitis |
R56 | T110 | T111 | associated_with | COX-2,cirrhosis |
R57 | T112 | T113 | associated_with | COX-2,cirrhosis |
R58 | T114 | T115 | associated_with | COX-2,hepatitis |
R59 | T116 | T117 | associated_with | COX-2,hepatitis |
R60 | T118 | T119 | associated_with | COX-2,cirrhosis |
R61 | T120 | T121 | associated_with | COX-2,cirrhosis |
R62 | T122 | T123 | associated_with | COX-2,hepatitis |
R63 | T124 | T125 | associated_with | COX-2,hepatitis |
R64 | T126 | T127 | associated_with | TNF-α,cirrhosis |
R65 | T128 | T129 | associated_with | TNF-α,cirrhosis |
R66 | T130 | T131 | associated_with | TNF-α,hepatitis |
R67 | T132 | T133 | associated_with | TNF-α,hepatitis |
R68 | T134 | T135 | associated_with | TNF-α,cirrhosis |
R69 | T136 | T137 | associated_with | TNF-α,cirrhosis |
R70 | T138 | T139 | associated_with | TNF-α,hepatitis |
R71 | T140 | T141 | associated_with | TNF-α,hepatitis |
R72 | T142 | T143 | associated_with | COX-2,cirrhosis |
R73 | T144 | T145 | associated_with | COX-2,cirrhosis |
R74 | T146 | T147 | associated_with | COX-2,hepatitis |
R75 | T148 | T149 | associated_with | COX-2,hepatitis |
R76 | T150 | T151 | associated_with | COX-2,cirrhosis |
R77 | T152 | T153 | associated_with | COX-2,cirrhosis |
R78 | T154 | T155 | associated_with | COX-2,hepatitis |
R79 | T156 | T157 | associated_with | COX-2,hepatitis |
R80 | T158 | T159 | associated_with | TNF-α,cirrhosis |
R81 | T160 | T161 | associated_with | TNF-α,cirrhosis |
R82 | T162 | T163 | associated_with | TNF-α,hepatitis |
R83 | T164 | T165 | associated_with | TNF-α,hepatitis |
R84 | T166 | T167 | associated_with | TNF-α,cirrhosis |
R85 | T168 | T169 | associated_with | TNF-α,cirrhosis |
R86 | T170 | T171 | associated_with | TNF-α,hepatitis |
R87 | T172 | T173 | associated_with | TNF-α,hepatitis |
R88 | T174 | T175 | associated_with | COX-2,cirrhosis |
R89 | T176 | T177 | associated_with | COX-2,cirrhosis |
R90 | T178 | T179 | associated_with | COX-2,hepatitis |
R91 | T180 | T181 | associated_with | COX-2,hepatitis |
R92 | T182 | T183 | associated_with | COX-2,cirrhosis |
R93 | T184 | T185 | associated_with | COX-2,cirrhosis |
R94 | T186 | T187 | associated_with | COX-2,hepatitis |
R95 | T188 | T189 | associated_with | COX-2,hepatitis |
R96 | T190 | T191 | associated_with | TNF-α,cirrhosis |
R97 | T192 | T193 | associated_with | TNF-α,cirrhosis |
R98 | T194 | T195 | associated_with | TNF-α,hepatitis |
R99 | T196 | T197 | associated_with | TNF-α,hepatitis |
R100 | T198 | T199 | associated_with | TNF-α,cirrhosis |
R101 | T200 | T201 | associated_with | TNF-α,cirrhosis |
R102 | T202 | T203 | associated_with | TNF-α,hepatitis |
R103 | T204 | T205 | associated_with | TNF-α,hepatitis |
R104 | T206 | T207 | associated_with | TNF-α,Hepatocarcinoma |
R105 | T208 | T209 | associated_with | NF-κB,Hepatocarcinoma |
R106 | T210 | T211 | associated_with | COX-2,Hepatocarcinoma |
R107 | T212 | T213 | associated_with | TLR4,hepatocarcinoma |
R108 | T214 | T215 | associated_with | TLR4,cirrhosis |
R109 | T216 | T217 | associated_with | TLR4,cirrhosis |
R110 | T218 | T219 | associated_with | TLR4,hepatitis |
R111 | T220 | T221 | associated_with | TLR4,hepatitis |
R112 | T222 | T223 | associated_with | TLR2,hepatocarcinoma |
R113 | T224 | T225 | associated_with | TLR2,cirrhosis |
R114 | T226 | T227 | associated_with | TLR2,cirrhosis |
R115 | T228 | T229 | associated_with | TLR2,hepatitis |
R116 | T230 | T231 | associated_with | TLR2,hepatitis |
PubmedHPO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 309-332 | HP_0002910 | denotes | transaminases elevation |
T2 | 441-450 | HP_0001394 | denotes | cirrhosis |
T3 | 452-461 | HP_0001394 | denotes | cirrhosis |
T4 | 850-859 | HP_0001394 | denotes | cirrhosis |
T5 | 1111-1120 | HP_0001394 | denotes | cirrhosis |
T6 | 1259-1268 | HP_0001394 | denotes | cirrhosis |
T7 | 1561-1570 | HP_0001394 | denotes | cirrhosis |
Allie
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
SS1_22330637_1_0 | 182-198 | expanded | denotes | cyclooxygenase-2 |
SS2_22330637_1_0 | 200-205 | abbr | denotes | COX-2 |
AE1_22330637_1_0 | SS1_22330637_1_0 | SS2_22330637_1_0 | abbreviatedTo | cyclooxygenase-2,COX-2 |