PubMed:22295085 / 817-1264 JSONTXT

{"project":"DisGeNET5_gene_disease","denotations":[{"id":"22295085-0#63#85#diseaseC0027859","span":{"begin":0,"end":447},"obj":"diseaseC0027859"}],"text":"ve activity assessed using the Ki-67 labeling index were evaluated. We found 18 mutations in 16 cases of 30 schwannomas (53%). The mutations included eight frameshift mutations, seven nonsense mutations, one in-frame deletion, one splicing donor site, and one missense mutation. Nine patients (30%) showed allelic loss. No patient had aberrant hypermethylation of the NF2 gene and correlation between NF2 genetic alterations and tumor behavior was"}