PubMed:22182687 / 0-876 JSON TXT

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Id	Subject	Object	Predicate	Lexical cue
T1	131-667	BACKGROUND	denotes	Fluorescent tags, including small organic molecules and fluorescent proteins, enable the localization of protein molecules in biomedical research experiments. However, the use of these labels may interfere with the formation of larger-scale protein structures such as amyloid aggregates. Therefore, we investigate the effects of some commonly used fluorescent tags on the morphologies of fibrils grown from the Alzheimer's disease-associated peptide Amyloid β 1-40 (Aβ40) and the Parkinson's disease-associated protein α-synuclein (αS).

Id	Subject	Object	Predicate	Lexical cue
T1	399-406	HP_0011034	denotes	amyloid
T2	542-561	HP_0002511	denotes	Alzheimer's disease
T3	581-588	HP_0011034	denotes	Amyloid
T4	611-620	HP_0001300	denotes	Parkinson

Id	Subject	Object	Predicate	Lexical cue
SS1_22182687_4_0	581-595	expanded	denotes	Amyloid β 1-40
SS2_22182687_4_0	597-601	abbr	denotes	Aβ40
SS1_22182687_4_1	650-661	expanded	denotes	α-synuclein
SS2_22182687_4_1	663-665	abbr	denotes	αS
SS1_22182687_6_0	683-715	expanded	denotes	transmission electron microscopy
SS2_22182687_6_0	717-720	abbr	denotes	TEM
AE1_22182687_4_0	SS1_22182687_4_0	SS2_22182687_4_0	abbreviatedTo	Amyloid β 1-40,Aβ40
AE1_22182687_4_1	SS1_22182687_4_1	SS2_22182687_4_1	abbreviatedTo	α-synuclein,αS
AE1_22182687_6_0	SS1_22182687_6_0	SS2_22182687_6_0	abbreviatedTo	transmission electron microscopy,TEM