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PubMed:22143985 JSONTXT

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Glycan-Motif

Id Subject Object Predicate Lexical cue
T1 12-27 https://glytoucan.org/Structures/Glycans/G57321FI denotes Tn antigenicity
T2 123-133 https://glytoucan.org/Structures/Glycans/G57321FI denotes Tn antigen
T3 162-183 https://glytoucan.org/Structures/Glycans/G27025MB denotes N-acetylgalactosamine
T4 317-327 https://glytoucan.org/Structures/Glycans/G57321FI denotes Tn antigen
T5 411-426 https://glytoucan.org/Structures/Glycans/G57321FI denotes Tn antigenicity
T6 604-614 https://glytoucan.org/Structures/Glycans/G57321FI denotes Tn antigen
T7 1048-1058 https://glytoucan.org/Structures/Glycans/G57321FI denotes Tn antigen
T8 1178-1188 https://glytoucan.org/Structures/Glycans/G57321FI denotes Tn antigen
T9 1567-1577 https://glytoucan.org/Structures/Glycans/G57321FI denotes Tn antigen
T10 1642-1652 https://glytoucan.org/Structures/Glycans/G57321FI denotes Tn antigen

GlyCosmos6-Glycan-Motif-Image

Id Subject Object Predicate Lexical cue image
T1 12-27 Glycan_Motif denotes Tn antigenicity https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G57321FI
T2 123-133 Glycan_Motif denotes Tn antigen https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G57321FI
T3 162-183 Glycan_Motif denotes N-acetylgalactosamine https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G27025MB
T4 317-327 Glycan_Motif denotes Tn antigen https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G57321FI
T5 411-426 Glycan_Motif denotes Tn antigenicity https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G57321FI
T6 604-614 Glycan_Motif denotes Tn antigen https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G57321FI
T7 1048-1058 Glycan_Motif denotes Tn antigen https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G57321FI
T8 1178-1188 Glycan_Motif denotes Tn antigen https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G57321FI
T9 1567-1577 Glycan_Motif denotes Tn antigen https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G57321FI
T10 1642-1652 Glycan_Motif denotes Tn antigen https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G57321FI

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-113 Sentence denotes Analysis of Tn antigenicity with a panel of new IgM and IgG1 monoclonal antibodies raised against leukemic cells.
TextSentencer_T2 114-277 Sentence denotes CD175 or Tn antigen is a carbohydrate moiety of N-acetylgalactosamine (GalNAc)α1-O- linked to the residue of amino acid serine or threonine in a polypeptide chain.
TextSentencer_T3 278-452 Sentence denotes Despite the chemical simplicity of the Tn antigen, its antigenic structure is considered to be complex and the clear determinants of Tn antigenicity remain poorly understood.
TextSentencer_T4 453-547 Sentence denotes As a consequence, a broad variety of anti-Tn monoclonal antibodies (mAbs) have been generated.
TextSentencer_T5 548-819 Sentence denotes To further investigate the nature and complexity of the Tn antigen, we generated seven different anti-Tn mAbs of IgM and IgG classes raised against human Jurkat T cells, which are Tn-positive due to the low activity of T-synthase and mutation in specific chaperone Cosmc.
TextSentencer_T6 820-997 Sentence denotes The binding analysis of anti-Tn mAbs with the array of synthetic saccharides, glycopeptides and O-glycoproteins revealed unexpected differences in specificities of anti-Tn mAbs.
TextSentencer_T7 998-1140 Sentence denotes IgM mAbs bound the terminal GalNAc residue of the Tn antigen irrespective of the peptide context or with low selectivity to the glycoproteins.
TextSentencer_T8 1141-1232 Sentence denotes In contrast, IgG mAbs recognized the Tn antigen in the context of a specific peptide motif.
TextSentencer_T9 1233-1373 Sentence denotes Particularly, JA3 mAb reacted to the GSPP or GSPAPP, and JA5 mAb recognized specifically the GSP motif (glycosylation sites are underlined).
TextSentencer_T10 1374-1532 Sentence denotes The major O-glycan carrier proteins CD43 and CD162 and isoforms of CD45 expressed on Jurkat cells were precipitated by anti-Tn mAbs with different affinities.
TextSentencer_T11 1533-1718 Sentence denotes In summary, our data suggest that Tn antigen-Ab binding capacity is determined by the peptide context of the Tn antigen, antigenic specificity of the Ab and class of the immunoglobulin.
TextSentencer_T12 1719-1893 Sentence denotes The newly generated anti-Tn IgG mAbs with the strong specificity to glycoprotein CD43 can be particularly interesting for the application in leukemia diagnostics and therapy.
T1 0-113 Sentence denotes Analysis of Tn antigenicity with a panel of new IgM and IgG1 monoclonal antibodies raised against leukemic cells.
T2 114-277 Sentence denotes CD175 or Tn antigen is a carbohydrate moiety of N-acetylgalactosamine (GalNAc)α1-O- linked to the residue of amino acid serine or threonine in a polypeptide chain.
T3 278-452 Sentence denotes Despite the chemical simplicity of the Tn antigen, its antigenic structure is considered to be complex and the clear determinants of Tn antigenicity remain poorly understood.
T4 453-547 Sentence denotes As a consequence, a broad variety of anti-Tn monoclonal antibodies (mAbs) have been generated.
T5 548-997 Sentence denotes To further investigate the nature and complexity of the Tn antigen, we generated seven different anti-Tn mAbs of IgM and IgG classes raised against human Jurkat T cells, which are Tn-positive due to the low activity of T-synthase and mutation in specific chaperone Cosmc. The binding analysis of anti-Tn mAbs with the array of synthetic saccharides, glycopeptides and O-glycoproteins revealed unexpected differences in specificities of anti-Tn mAbs.
T6 998-1140 Sentence denotes IgM mAbs bound the terminal GalNAc residue of the Tn antigen irrespective of the peptide context or with low selectivity to the glycoproteins.
T7 1141-1232 Sentence denotes In contrast, IgG mAbs recognized the Tn antigen in the context of a specific peptide motif.
T8 1233-1373 Sentence denotes Particularly, JA3 mAb reacted to the GSPP or GSPAPP, and JA5 mAb recognized specifically the GSP motif (glycosylation sites are underlined).
T9 1374-1532 Sentence denotes The major O-glycan carrier proteins CD43 and CD162 and isoforms of CD45 expressed on Jurkat cells were precipitated by anti-Tn mAbs with different affinities.
T10 1533-1718 Sentence denotes In summary, our data suggest that Tn antigen-Ab binding capacity is determined by the peptide context of the Tn antigen, antigenic specificity of the Ab and class of the immunoglobulin.
T11 1719-1893 Sentence denotes The newly generated anti-Tn IgG mAbs with the strong specificity to glycoprotein CD43 can be particularly interesting for the application in leukemia diagnostics and therapy.
T1 0-113 Sentence denotes Analysis of Tn antigenicity with a panel of new IgM and IgG1 monoclonal antibodies raised against leukemic cells.
T2 114-277 Sentence denotes CD175 or Tn antigen is a carbohydrate moiety of N-acetylgalactosamine (GalNAc)α1-O- linked to the residue of amino acid serine or threonine in a polypeptide chain.
T3 278-452 Sentence denotes Despite the chemical simplicity of the Tn antigen, its antigenic structure is considered to be complex and the clear determinants of Tn antigenicity remain poorly understood.
T4 453-547 Sentence denotes As a consequence, a broad variety of anti-Tn monoclonal antibodies (mAbs) have been generated.
T5 548-819 Sentence denotes To further investigate the nature and complexity of the Tn antigen, we generated seven different anti-Tn mAbs of IgM and IgG classes raised against human Jurkat T cells, which are Tn-positive due to the low activity of T-synthase and mutation in specific chaperone Cosmc.
T6 820-997 Sentence denotes The binding analysis of anti-Tn mAbs with the array of synthetic saccharides, glycopeptides and O-glycoproteins revealed unexpected differences in specificities of anti-Tn mAbs.
T7 998-1140 Sentence denotes IgM mAbs bound the terminal GalNAc residue of the Tn antigen irrespective of the peptide context or with low selectivity to the glycoproteins.
T8 1141-1232 Sentence denotes In contrast, IgG mAbs recognized the Tn antigen in the context of a specific peptide motif.
T9 1233-1373 Sentence denotes Particularly, JA3 mAb reacted to the GSPP or GSPAPP, and JA5 mAb recognized specifically the GSP motif (glycosylation sites are underlined).
T10 1374-1532 Sentence denotes The major O-glycan carrier proteins CD43 and CD162 and isoforms of CD45 expressed on Jurkat cells were precipitated by anti-Tn mAbs with different affinities.
T11 1533-1718 Sentence denotes In summary, our data suggest that Tn antigen-Ab binding capacity is determined by the peptide context of the Tn antigen, antigenic specificity of the Ab and class of the immunoglobulin.
T12 1719-1893 Sentence denotes The newly generated anti-Tn IgG mAbs with the strong specificity to glycoprotein CD43 can be particularly interesting for the application in leukemia diagnostics and therapy.

GlyCosmos6-Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 12-27 https://glytoucan.org/Structures/Glycans/G57321FI denotes Tn antigenicity
T2 123-133 https://glytoucan.org/Structures/Glycans/G57321FI denotes Tn antigen
T3 162-183 https://glytoucan.org/Structures/Glycans/G27025MB denotes N-acetylgalactosamine
T4 317-327 https://glytoucan.org/Structures/Glycans/G57321FI denotes Tn antigen
T5 411-426 https://glytoucan.org/Structures/Glycans/G57321FI denotes Tn antigenicity
T6 604-614 https://glytoucan.org/Structures/Glycans/G57321FI denotes Tn antigen
T7 1048-1058 https://glytoucan.org/Structures/Glycans/G57321FI denotes Tn antigen
T8 1178-1188 https://glytoucan.org/Structures/Glycans/G57321FI denotes Tn antigen
T9 1567-1577 https://glytoucan.org/Structures/Glycans/G57321FI denotes Tn antigen
T10 1642-1652 https://glytoucan.org/Structures/Glycans/G57321FI denotes Tn antigen

Glycosmos6-GlycoEpitope

Id Subject Object Predicate Lexical cue
T1 123-133 http://www.glycoepitope.jp/epitopes/EP0021 denotes Tn antigen
T2 317-327 http://www.glycoepitope.jp/epitopes/EP0021 denotes Tn antigen
T3 604-614 http://www.glycoepitope.jp/epitopes/EP0021 denotes Tn antigen
T4 1048-1058 http://www.glycoepitope.jp/epitopes/EP0021 denotes Tn antigen
T5 1178-1188 http://www.glycoepitope.jp/epitopes/EP0021 denotes Tn antigen
T6 1567-1577 http://www.glycoepitope.jp/epitopes/EP0021 denotes Tn antigen
T7 1642-1652 http://www.glycoepitope.jp/epitopes/EP0021 denotes Tn antigen

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 1860-1868 HP_0001909 denotes leukemia

GlycoBiology-FMA

Id Subject Object Predicate Lexical cue
_T1 48-51 FMAID:167182 denotes IgM
_T2 72-82 FMAID:167180 denotes antibodies
_T3 107-112 FMAID:68646 denotes cells
_T4 107-112 FMAID:169002 denotes cells
_T5 139-151 FMAID:82737 denotes carbohydrate
_T6 139-151 FMAID:197276 denotes carbohydrate
_T7 162-183 FMAID:196780 denotes N-acetylgalactosamine
_T8 162-183 FMAID:82786 denotes N-acetylgalactosamine
_T9 223-233 FMAID:196728 denotes amino acid
_T10 223-233 FMAID:82739 denotes amino acid
_T11 234-240 FMAID:165609 denotes serine
_T12 234-240 FMAID:196753 denotes serine
_T13 234-240 FMAID:67710 denotes serine
_T14 234-240 FMAID:82764 denotes serine
_T15 244-253 FMAID:82765 denotes threonine
_T16 244-253 FMAID:196754 denotes threonine
_T17 509-519 FMAID:167180 denotes antibodies
_T18 661-664 FMAID:167182 denotes IgM
_T19 669-672 FMAID:167179 denotes IgG
_T20 711-716 FMAID:68646 denotes cells
_T21 711-716 FMAID:169002 denotes cells
_T22 885-896 FMAID:196733 denotes saccharides
_T23 885-896 FMAID:82744 denotes saccharides
_T24 898-911 FMAID:196778 denotes glycopeptides
_T25 898-911 FMAID:82784 denotes glycopeptides
_T26 918-931 FMAID:62925 denotes glycoproteins
_T27 918-931 FMAID:167256 denotes glycoproteins
_T28 998-1001 FMAID:167182 denotes IgM
_T29 1126-1139 FMAID:62925 denotes glycoproteins
_T30 1126-1139 FMAID:167256 denotes glycoproteins
_T31 1154-1157 FMAID:167179 denotes IgG
_T32 1401-1409 FMAID:67257 denotes proteins
_T33 1401-1409 FMAID:165447 denotes proteins
_T34 1466-1471 FMAID:68646 denotes cells
_T35 1466-1471 FMAID:169002 denotes cells
_T36 1703-1717 FMAID:167187 denotes immunoglobulin
_T37 1703-1717 FMAID:62872 denotes immunoglobulin
_T38 1703-1717 FMAID:167178 denotes immunoglobulin
_T39 1703-1717 FMAID:167181 denotes immunoglobulin
_T40 1703-1717 FMAID:62873 denotes immunoglobulin
_T41 1703-1717 FMAID:167185 denotes immunoglobulin
_T42 1703-1717 FMAID:62876 denotes immunoglobulin
_T43 1703-1717 FMAID:62874 denotes immunoglobulin
_T44 1703-1717 FMAID:167183 denotes immunoglobulin
_T45 1703-1717 FMAID:167177 denotes immunoglobulin
_T46 1703-1717 FMAID:62871 denotes immunoglobulin
_T47 1703-1717 FMAID:62875 denotes immunoglobulin
_T48 1747-1750 FMAID:167179 denotes IgG
_T49 1787-1799 FMAID:167256 denotes glycoprotein
_T50 1787-1799 FMAID:62925 denotes glycoprotein

uniprot-human

Id Subject Object Predicate Lexical cue
T1 1326-1329 http://www.uniprot.org/uniprot/Q5JWD4 denotes GSP
T2 1410-1414 http://www.uniprot.org/uniprot/P16150 denotes CD43
T3 1800-1804 http://www.uniprot.org/uniprot/P16150 denotes CD43
T4 1419-1424 http://www.uniprot.org/uniprot/Q14242 denotes CD162
T5 1441-1445 http://www.uniprot.org/uniprot/P08575 denotes CD45

uniprot-mouse

Id Subject Object Predicate Lexical cue
T1 813-818 http://www.uniprot.org/uniprot/Q9JMG2 denotes Cosmc
T2 1410-1414 http://www.uniprot.org/uniprot/P15702 denotes CD43
T3 1800-1804 http://www.uniprot.org/uniprot/P15702 denotes CD43
T4 1419-1424 http://www.uniprot.org/uniprot/Q62170 denotes CD162
T5 1441-1445 http://www.uniprot.org/uniprot/P06800 denotes CD45

GlycoBiology-NCBITAXON

Id Subject Object Predicate Lexical cue
T1 61-71 http://purl.bioontology.org/ontology/NCBITAXON/608684 denotes monoclonal
T2 107-112 http://purl.bioontology.org/ontology/STY/T025 denotes cells
T3 498-508 http://purl.bioontology.org/ontology/NCBITAXON/608684 denotes monoclonal
T4 711-716 http://purl.bioontology.org/ontology/STY/T025 denotes cells
T5 1466-1471 http://purl.bioontology.org/ontology/STY/T025 denotes cells

GO-BP

Id Subject Object Predicate Lexical cue
T1 1337-1350 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation

GO-MF

Id Subject Object Predicate Lexical cue
T1 72-82 http://purl.obolibrary.org/obo/GO_0003823 denotes antibodies
T2 509-519 http://purl.obolibrary.org/obo/GO_0003823 denotes antibodies
T3 824-831 http://purl.obolibrary.org/obo/GO_0070026 denotes binding
T4 1581-1588 http://purl.obolibrary.org/obo/GO_0070026 denotes binding
T5 824-831 http://purl.obolibrary.org/obo/GO_0003680 denotes binding
T6 1581-1588 http://purl.obolibrary.org/obo/GO_0003680 denotes binding
T7 824-831 http://purl.obolibrary.org/obo/GO_0017091 denotes binding
T8 1581-1588 http://purl.obolibrary.org/obo/GO_0017091 denotes binding
T9 824-831 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T10 1581-1588 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T11 1703-1717 http://purl.obolibrary.org/obo/GO_0003823 denotes immunoglobulin

GO-CC

Id Subject Object Predicate Lexical cue
T1 56-60 http://purl.obolibrary.org/obo/GO_0071735 denotes IgG1
T2 107-112 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T3 711-716 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T4 1466-1471 http://purl.obolibrary.org/obo/GO_0005623 denotes cells

Allie

Id Subject Object Predicate Lexical cue
SS1_22143985_3_0 498-519 expanded denotes monoclonal antibodies
SS2_22143985_3_0 521-525 abbr denotes mAbs
AE1_22143985_3_0 SS1_22143985_3_0 SS2_22143985_3_0 abbreviatedTo monoclonal antibodies,mAbs

EDAM-topics

Id Subject Object Predicate Lexical cue
T1 15-27 http://edamontology.org/topic_2830 denotes antigenicity
T2 126-133 http://edamontology.org/topic_2830 denotes antigen
T3 139-151 http://edamontology.org/topic_0152 denotes carbohydrate
T4 223-233 http://edamontology.org/topic_0154 denotes amino acid
T5 320-327 http://edamontology.org/topic_2830 denotes antigen
T6 333-342 http://edamontology.org/topic_2830 denotes antigenic
T7 414-426 http://edamontology.org/topic_2830 denotes antigenicity
T8 607-614 http://edamontology.org/topic_2830 denotes antigen
T9 696-701 http://edamontology.org/topic_2815 denotes human
T10 782-790 http://edamontology.org/topic_0199 denotes mutation
T11 1017-1025 http://edamontology.org/topic_0749 denotes terminal
T12 1051-1058 http://edamontology.org/topic_2830 denotes antigen
T13 1079-1086 http://edamontology.org/topic_0154 denotes peptide
T14 1181-1188 http://edamontology.org/topic_2830 denotes antigen
T15 1218-1225 http://edamontology.org/topic_0154 denotes peptide
T16 1226-1231 http://edamontology.org/topic_0158 denotes motif
T17 1330-1335 http://edamontology.org/topic_0158 denotes motif
T18 1401-1409 http://edamontology.org/topic_0078 denotes proteins
T19 1570-1577 http://edamontology.org/topic_2830 denotes antigen
T20 1619-1626 http://edamontology.org/topic_0154 denotes peptide
T21 1645-1652 http://edamontology.org/topic_2830 denotes antigen
T22 1654-1663 http://edamontology.org/topic_2830 denotes antigenic

EDAM-DFO

Id Subject Object Predicate Lexical cue
T1 0-8 http://edamontology.org/operation_2945 denotes Analysis
T2 212-219 http://edamontology.org/data_1756 denotes residue
T3 259-276 http://edamontology.org/data_1008 denotes polypeptide chain
T4 343-352 http://edamontology.org/data_0883 denotes structure
T5 343-355 http://edamontology.org/data_1070 denotes structure is
T6 537-546 http://edamontology.org/operation_3429 denotes generated
T7 619-628 http://edamontology.org/operation_3429 denotes generated
T8 832-840 http://edamontology.org/operation_2945 denotes analysis
T9 866-871 http://edamontology.org/data_2082 denotes array
T10 1033-1040 http://edamontology.org/data_1756 denotes residue
T11 1079-1086 http://edamontology.org/data_2906 denotes peptide
T12 1218-1225 http://edamontology.org/data_2906 denotes peptide
T13 1401-1409 http://edamontology.org/data_1467 denotes proteins
T14 1401-1409 http://edamontology.org/format_1208 denotes proteins
T15 1549-1553 http://edamontology.org/data_0006 denotes data
T16 1619-1626 http://edamontology.org/data_2906 denotes peptide
T17 1729-1738 http://edamontology.org/operation_3429 denotes generated

GlyTouCan-IUPAC

Id Subject Object Predicate Lexical cue
GlycanIUPAC_T1 185-191 "http://rdf.glycoinfo.org/glycan/G23425WZ" denotes GalNAc
GlycanIUPAC_T2 1026-1032 "http://rdf.glycoinfo.org/glycan/G23425WZ" denotes GalNAc
GlycanIUPAC_T3 185-191 "http://rdf.glycoinfo.org/glycan/G02874VH" denotes GalNAc
GlycanIUPAC_T4 1026-1032 "http://rdf.glycoinfo.org/glycan/G02874VH" denotes GalNAc
GlycanIUPAC_T5 185-191 "http://rdf.glycoinfo.org/glycan/G99699DW" denotes GalNAc
GlycanIUPAC_T6 1026-1032 "http://rdf.glycoinfo.org/glycan/G99699DW" denotes GalNAc
GlycanIUPAC_T7 185-191 "http://rdf.glycoinfo.org/glycan/G22074RM" denotes GalNAc
GlycanIUPAC_T8 1026-1032 "http://rdf.glycoinfo.org/glycan/G22074RM" denotes GalNAc
GlycanIUPAC_T9 185-191 "http://rdf.glycoinfo.org/glycan/G48535VZ" denotes GalNAc
GlycanIUPAC_T10 1026-1032 "http://rdf.glycoinfo.org/glycan/G48535VZ" denotes GalNAc
GlycanIUPAC_T11 185-191 "http://rdf.glycoinfo.org/glycan/G39738WL" denotes GalNAc
GlycanIUPAC_T12 1026-1032 "http://rdf.glycoinfo.org/glycan/G39738WL" denotes GalNAc
GlycanIUPAC_T13 185-191 "http://rdf.glycoinfo.org/glycan/G42313WU" denotes GalNAc
GlycanIUPAC_T14 1026-1032 "http://rdf.glycoinfo.org/glycan/G42313WU" denotes GalNAc
GlycanIUPAC_T15 185-191 "http://rdf.glycoinfo.org/glycan/G00393CK" denotes GalNAc
GlycanIUPAC_T16 1026-1032 "http://rdf.glycoinfo.org/glycan/G00393CK" denotes GalNAc
GlycanIUPAC_T17 185-191 "http://rdf.glycoinfo.org/glycan/G42649EX" denotes GalNAc
GlycanIUPAC_T18 1026-1032 "http://rdf.glycoinfo.org/glycan/G42649EX" denotes GalNAc
GlycanIUPAC_T19 185-191 "http://rdf.glycoinfo.org/glycan/G46880SB" denotes GalNAc
GlycanIUPAC_T20 1026-1032 "http://rdf.glycoinfo.org/glycan/G46880SB" denotes GalNAc
GlycanIUPAC_T21 185-191 "http://rdf.glycoinfo.org/glycan/G75599IR" denotes GalNAc
GlycanIUPAC_T22 1026-1032 "http://rdf.glycoinfo.org/glycan/G75599IR" denotes GalNAc
GlycanIUPAC_T23 185-191 "http://rdf.glycoinfo.org/glycan/G58985MU" denotes GalNAc
GlycanIUPAC_T24 1026-1032 "http://rdf.glycoinfo.org/glycan/G58985MU" denotes GalNAc
GlycanIUPAC_T25 185-191 "http://rdf.glycoinfo.org/glycan/G92517PO" denotes GalNAc
GlycanIUPAC_T26 1026-1032 "http://rdf.glycoinfo.org/glycan/G92517PO" denotes GalNAc
GlycanIUPAC_T27 185-191 "http://rdf.glycoinfo.org/glycan/G88512YL" denotes GalNAc
GlycanIUPAC_T28 1026-1032 "http://rdf.glycoinfo.org/glycan/G88512YL" denotes GalNAc
GlycanIUPAC_T29 185-191 "http://rdf.glycoinfo.org/glycan/G41473NX" denotes GalNAc
GlycanIUPAC_T30 1026-1032 "http://rdf.glycoinfo.org/glycan/G41473NX" denotes GalNAc
GlycanIUPAC_T31 185-191 "http://rdf.glycoinfo.org/glycan/G71089RB" denotes GalNAc
GlycanIUPAC_T32 1026-1032 "http://rdf.glycoinfo.org/glycan/G71089RB" denotes GalNAc
GlycanIUPAC_T33 185-191 "http://rdf.glycoinfo.org/glycan/G73485GZ" denotes GalNAc
GlycanIUPAC_T34 1026-1032 "http://rdf.glycoinfo.org/glycan/G73485GZ" denotes GalNAc
GlycanIUPAC_T35 185-191 "http://rdf.glycoinfo.org/glycan/G61406KC" denotes GalNAc
GlycanIUPAC_T36 1026-1032 "http://rdf.glycoinfo.org/glycan/G61406KC" denotes GalNAc
GlycanIUPAC_T37 185-191 "http://rdf.glycoinfo.org/glycan/G34412GZ" denotes GalNAc
GlycanIUPAC_T38 1026-1032 "http://rdf.glycoinfo.org/glycan/G34412GZ" denotes GalNAc
GlycanIUPAC_T39 185-191 "http://rdf.glycoinfo.org/glycan/G67209FP" denotes GalNAc
GlycanIUPAC_T40 1026-1032 "http://rdf.glycoinfo.org/glycan/G67209FP" denotes GalNAc
GlycanIUPAC_T41 185-191 "http://rdf.glycoinfo.org/glycan/G61442IL" denotes GalNAc
GlycanIUPAC_T42 1026-1032 "http://rdf.glycoinfo.org/glycan/G61442IL" denotes GalNAc
GlycanIUPAC_T43 185-191 "http://rdf.glycoinfo.org/glycan/G93729MV" denotes GalNAc
GlycanIUPAC_T44 1026-1032 "http://rdf.glycoinfo.org/glycan/G93729MV" denotes GalNAc
GlycanIUPAC_T45 185-191 "http://rdf.glycoinfo.org/glycan/G92144AE" denotes GalNAc
GlycanIUPAC_T46 1026-1032 "http://rdf.glycoinfo.org/glycan/G92144AE" denotes GalNAc

Lectin

Id Subject Object Predicate Lexical cue
Lectin_T1 12-14 https://acgg.asia/db/lfdb/LfDB0021 denotes Tn
Lectin_T2 123-125 https://acgg.asia/db/lfdb/LfDB0021 denotes Tn
Lectin_T3 317-319 https://acgg.asia/db/lfdb/LfDB0021 denotes Tn
Lectin_T4 411-413 https://acgg.asia/db/lfdb/LfDB0021 denotes Tn
Lectin_T5 495-497 https://acgg.asia/db/lfdb/LfDB0021 denotes Tn
Lectin_T6 604-606 https://acgg.asia/db/lfdb/LfDB0021 denotes Tn
Lectin_T7 650-652 https://acgg.asia/db/lfdb/LfDB0021 denotes Tn
Lectin_T8 728-730 https://acgg.asia/db/lfdb/LfDB0021 denotes Tn
Lectin_T9 849-851 https://acgg.asia/db/lfdb/LfDB0021 denotes Tn
Lectin_T10 989-991 https://acgg.asia/db/lfdb/LfDB0021 denotes Tn
Lectin_T11 1048-1050 https://acgg.asia/db/lfdb/LfDB0021 denotes Tn
Lectin_T12 1178-1180 https://acgg.asia/db/lfdb/LfDB0021 denotes Tn
Lectin_T13 1498-1500 https://acgg.asia/db/lfdb/LfDB0021 denotes Tn
Lectin_T14 1567-1569 https://acgg.asia/db/lfdb/LfDB0021 denotes Tn
Lectin_T15 1642-1644 https://acgg.asia/db/lfdb/LfDB0021 denotes Tn
Lectin_T16 1744-1746 https://acgg.asia/db/lfdb/LfDB0021 denotes Tn

GlycoBiology-Epitope

Id Subject Object Predicate Lexical cue
PD-GlycoEpitope-B_T1 12-27 http://www.glycoepitope.jp/epitopes/EP0021 denotes Tn antigenicity
PD-GlycoEpitope-B_T2 123-133 http://www.glycoepitope.jp/epitopes/EP0021 denotes Tn antigen
PD-GlycoEpitope-B_T3 317-327 http://www.glycoepitope.jp/epitopes/EP0021 denotes Tn antigen
PD-GlycoEpitope-B_T4 411-426 http://www.glycoepitope.jp/epitopes/EP0021 denotes Tn antigenicity
PD-GlycoEpitope-B_T5 604-614 http://www.glycoepitope.jp/epitopes/EP0021 denotes Tn antigen
PD-GlycoEpitope-B_T6 1048-1058 http://www.glycoepitope.jp/epitopes/EP0021 denotes Tn antigen
PD-GlycoEpitope-B_T7 1178-1188 http://www.glycoepitope.jp/epitopes/EP0021 denotes Tn antigen
PD-GlycoEpitope-B_T8 1567-1577 http://www.glycoepitope.jp/epitopes/EP0021 denotes Tn antigen
PD-GlycoEpitope-B_T9 1642-1652 http://www.glycoepitope.jp/epitopes/EP0021 denotes Tn antigen

mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 1860-1868 Disease denotes leukemia http://purl.obolibrary.org/obo/MONDO_0005059

HP-phenotype

Id Subject Object Predicate Lexical cue hp_id
T1 1860-1868 Phenotype denotes leukemia HP:0001909

Glycan-GlyCosmos

Id Subject Object Predicate Lexical cue image
T1 123-133 Glycan denotes Tn antigen https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI
T2 185-191 Glycan denotes GalNAc https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL
T3 317-327 Glycan denotes Tn antigen https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI
T4 604-614 Glycan denotes Tn antigen https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI
T5 1026-1032 Glycan denotes GalNAc https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL
T6 1048-1058 Glycan denotes Tn antigen https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI
T7 1178-1188 Glycan denotes Tn antigen https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI
T8 1567-1577 Glycan denotes Tn antigen https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI
T9 1642-1652 Glycan denotes Tn antigen https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI

GlyCosmos-GlycoEpitope

Id Subject Object Predicate Lexical cue glycoepitope_id
T1 123-133 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn antigen http://www.glycoepitope.jp/epitopes/EP0021
T2 317-327 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn antigen http://www.glycoepitope.jp/epitopes/EP0021
T3 604-614 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn antigen http://www.glycoepitope.jp/epitopes/EP0021
T4 1048-1058 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn antigen http://www.glycoepitope.jp/epitopes/EP0021
T5 1178-1188 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn antigen http://www.glycoepitope.jp/epitopes/EP0021
T6 1567-1577 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn antigen http://www.glycoepitope.jp/epitopes/EP0021
T7 1642-1652 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn antigen http://www.glycoepitope.jp/epitopes/EP0021

GlyCosmos15-HP

Id Subject Object Predicate Lexical cue hp_id
T1 1860-1868 Phenotype denotes leukemia HP:0001909

GlyCosmos15-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 1860-1868 Disease denotes leukemia http://purl.obolibrary.org/obo/MONDO_0005059

GlyCosmos15-NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 696-701 OrganismTaxon denotes human 9606

GlyCosmos15-CL

Id Subject Object Predicate Lexical cue cl_id
T1 709-716 Cell denotes T cells http://purl.obolibrary.org/obo/CL:0000084

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-113 Sentence denotes Analysis of Tn antigenicity with a panel of new IgM and IgG1 monoclonal antibodies raised against leukemic cells.
TextSentencer_T2 114-277 Sentence denotes CD175 or Tn antigen is a carbohydrate moiety of N-acetylgalactosamine (GalNAc)α1-O- linked to the residue of amino acid serine or threonine in a polypeptide chain.
TextSentencer_T3 278-452 Sentence denotes Despite the chemical simplicity of the Tn antigen, its antigenic structure is considered to be complex and the clear determinants of Tn antigenicity remain poorly understood.
TextSentencer_T4 453-547 Sentence denotes As a consequence, a broad variety of anti-Tn monoclonal antibodies (mAbs) have been generated.
TextSentencer_T5 548-819 Sentence denotes To further investigate the nature and complexity of the Tn antigen, we generated seven different anti-Tn mAbs of IgM and IgG classes raised against human Jurkat T cells, which are Tn-positive due to the low activity of T-synthase and mutation in specific chaperone Cosmc.
TextSentencer_T6 820-997 Sentence denotes The binding analysis of anti-Tn mAbs with the array of synthetic saccharides, glycopeptides and O-glycoproteins revealed unexpected differences in specificities of anti-Tn mAbs.
TextSentencer_T7 998-1140 Sentence denotes IgM mAbs bound the terminal GalNAc residue of the Tn antigen irrespective of the peptide context or with low selectivity to the glycoproteins.
TextSentencer_T8 1141-1232 Sentence denotes In contrast, IgG mAbs recognized the Tn antigen in the context of a specific peptide motif.
TextSentencer_T9 1233-1373 Sentence denotes Particularly, JA3 mAb reacted to the GSPP or GSPAPP, and JA5 mAb recognized specifically the GSP motif (glycosylation sites are underlined).
TextSentencer_T10 1374-1532 Sentence denotes The major O-glycan carrier proteins CD43 and CD162 and isoforms of CD45 expressed on Jurkat cells were precipitated by anti-Tn mAbs with different affinities.
TextSentencer_T11 1533-1718 Sentence denotes In summary, our data suggest that Tn antigen-Ab binding capacity is determined by the peptide context of the Tn antigen, antigenic specificity of the Ab and class of the immunoglobulin.
TextSentencer_T12 1719-1893 Sentence denotes The newly generated anti-Tn IgG mAbs with the strong specificity to glycoprotein CD43 can be particularly interesting for the application in leukemia diagnostics and therapy.
T1 0-113 Sentence denotes Analysis of Tn antigenicity with a panel of new IgM and IgG1 monoclonal antibodies raised against leukemic cells.
T2 114-277 Sentence denotes CD175 or Tn antigen is a carbohydrate moiety of N-acetylgalactosamine (GalNAc)α1-O- linked to the residue of amino acid serine or threonine in a polypeptide chain.
T3 278-452 Sentence denotes Despite the chemical simplicity of the Tn antigen, its antigenic structure is considered to be complex and the clear determinants of Tn antigenicity remain poorly understood.
T4 453-547 Sentence denotes As a consequence, a broad variety of anti-Tn monoclonal antibodies (mAbs) have been generated.
T5 548-997 Sentence denotes To further investigate the nature and complexity of the Tn antigen, we generated seven different anti-Tn mAbs of IgM and IgG classes raised against human Jurkat T cells, which are Tn-positive due to the low activity of T-synthase and mutation in specific chaperone Cosmc. The binding analysis of anti-Tn mAbs with the array of synthetic saccharides, glycopeptides and O-glycoproteins revealed unexpected differences in specificities of anti-Tn mAbs.
T6 998-1140 Sentence denotes IgM mAbs bound the terminal GalNAc residue of the Tn antigen irrespective of the peptide context or with low selectivity to the glycoproteins.
T7 1141-1232 Sentence denotes In contrast, IgG mAbs recognized the Tn antigen in the context of a specific peptide motif.
T8 1233-1373 Sentence denotes Particularly, JA3 mAb reacted to the GSPP or GSPAPP, and JA5 mAb recognized specifically the GSP motif (glycosylation sites are underlined).
T9 1374-1532 Sentence denotes The major O-glycan carrier proteins CD43 and CD162 and isoforms of CD45 expressed on Jurkat cells were precipitated by anti-Tn mAbs with different affinities.
T10 1533-1718 Sentence denotes In summary, our data suggest that Tn antigen-Ab binding capacity is determined by the peptide context of the Tn antigen, antigenic specificity of the Ab and class of the immunoglobulin.
T11 1719-1893 Sentence denotes The newly generated anti-Tn IgG mAbs with the strong specificity to glycoprotein CD43 can be particularly interesting for the application in leukemia diagnostics and therapy.
T1 0-113 Sentence denotes Analysis of Tn antigenicity with a panel of new IgM and IgG1 monoclonal antibodies raised against leukemic cells.
T2 114-277 Sentence denotes CD175 or Tn antigen is a carbohydrate moiety of N-acetylgalactosamine (GalNAc)α1-O- linked to the residue of amino acid serine or threonine in a polypeptide chain.
T3 278-452 Sentence denotes Despite the chemical simplicity of the Tn antigen, its antigenic structure is considered to be complex and the clear determinants of Tn antigenicity remain poorly understood.
T4 453-547 Sentence denotes As a consequence, a broad variety of anti-Tn monoclonal antibodies (mAbs) have been generated.
T5 548-819 Sentence denotes To further investigate the nature and complexity of the Tn antigen, we generated seven different anti-Tn mAbs of IgM and IgG classes raised against human Jurkat T cells, which are Tn-positive due to the low activity of T-synthase and mutation in specific chaperone Cosmc.
T6 820-997 Sentence denotes The binding analysis of anti-Tn mAbs with the array of synthetic saccharides, glycopeptides and O-glycoproteins revealed unexpected differences in specificities of anti-Tn mAbs.
T7 998-1140 Sentence denotes IgM mAbs bound the terminal GalNAc residue of the Tn antigen irrespective of the peptide context or with low selectivity to the glycoproteins.
T8 1141-1232 Sentence denotes In contrast, IgG mAbs recognized the Tn antigen in the context of a specific peptide motif.
T9 1233-1373 Sentence denotes Particularly, JA3 mAb reacted to the GSPP or GSPAPP, and JA5 mAb recognized specifically the GSP motif (glycosylation sites are underlined).
T10 1374-1532 Sentence denotes The major O-glycan carrier proteins CD43 and CD162 and isoforms of CD45 expressed on Jurkat cells were precipitated by anti-Tn mAbs with different affinities.
T11 1533-1718 Sentence denotes In summary, our data suggest that Tn antigen-Ab binding capacity is determined by the peptide context of the Tn antigen, antigenic specificity of the Ab and class of the immunoglobulin.
T12 1719-1893 Sentence denotes The newly generated anti-Tn IgG mAbs with the strong specificity to glycoprotein CD43 can be particularly interesting for the application in leukemia diagnostics and therapy.

GlyCosmos15-Sentences

Id Subject Object Predicate Lexical cue
T1 0-113 Sentence denotes Analysis of Tn antigenicity with a panel of new IgM and IgG1 monoclonal antibodies raised against leukemic cells.
T2 114-277 Sentence denotes CD175 or Tn antigen is a carbohydrate moiety of N-acetylgalactosamine (GalNAc)α1-O- linked to the residue of amino acid serine or threonine in a polypeptide chain.
T3 278-452 Sentence denotes Despite the chemical simplicity of the Tn antigen, its antigenic structure is considered to be complex and the clear determinants of Tn antigenicity remain poorly understood.
T4 453-547 Sentence denotes As a consequence, a broad variety of anti-Tn monoclonal antibodies (mAbs) have been generated.
T5 548-997 Sentence denotes To further investigate the nature and complexity of the Tn antigen, we generated seven different anti-Tn mAbs of IgM and IgG classes raised against human Jurkat T cells, which are Tn-positive due to the low activity of T-synthase and mutation in specific chaperone Cosmc. The binding analysis of anti-Tn mAbs with the array of synthetic saccharides, glycopeptides and O-glycoproteins revealed unexpected differences in specificities of anti-Tn mAbs.
T6 998-1140 Sentence denotes IgM mAbs bound the terminal GalNAc residue of the Tn antigen irrespective of the peptide context or with low selectivity to the glycoproteins.
T7 1141-1232 Sentence denotes In contrast, IgG mAbs recognized the Tn antigen in the context of a specific peptide motif.
T8 1233-1373 Sentence denotes Particularly, JA3 mAb reacted to the GSPP or GSPAPP, and JA5 mAb recognized specifically the GSP motif (glycosylation sites are underlined).
T9 1374-1532 Sentence denotes The major O-glycan carrier proteins CD43 and CD162 and isoforms of CD45 expressed on Jurkat cells were precipitated by anti-Tn mAbs with different affinities.
T10 1533-1718 Sentence denotes In summary, our data suggest that Tn antigen-Ab binding capacity is determined by the peptide context of the Tn antigen, antigenic specificity of the Ab and class of the immunoglobulin.
T11 1719-1893 Sentence denotes The newly generated anti-Tn IgG mAbs with the strong specificity to glycoprotein CD43 can be particularly interesting for the application in leukemia diagnostics and therapy.

GlyCosmos15-Glycan

Id Subject Object Predicate Lexical cue image
T1 123-133 Glycan denotes Tn antigen https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI
T2 185-191 Glycan denotes GalNAc https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL
T3 317-327 Glycan denotes Tn antigen https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI
T4 604-614 Glycan denotes Tn antigen https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI
T5 1026-1032 Glycan denotes GalNAc https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL
T6 1048-1058 Glycan denotes Tn antigen https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI
T7 1178-1188 Glycan denotes Tn antigen https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI
T8 1567-1577 Glycan denotes Tn antigen https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI
T9 1642-1652 Glycan denotes Tn antigen https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI

GlyCosmos15-GlycoEpitope

Id Subject Object Predicate Lexical cue glycoepitope_id
T1 123-133 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn antigen http://www.glycoepitope.jp/epitopes/EP0021
T2 317-327 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn antigen http://www.glycoepitope.jp/epitopes/EP0021
T3 604-614 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn antigen http://www.glycoepitope.jp/epitopes/EP0021
T4 1048-1058 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn antigen http://www.glycoepitope.jp/epitopes/EP0021
T5 1178-1188 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn antigen http://www.glycoepitope.jp/epitopes/EP0021
T6 1567-1577 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn antigen http://www.glycoepitope.jp/epitopes/EP0021
T7 1642-1652 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn antigen http://www.glycoepitope.jp/epitopes/EP0021

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 696-701 OrganismTaxon denotes human 9606

CL-cell

Id Subject Object Predicate Lexical cue cl_id
T1 709-716 Cell denotes T cells http://purl.obolibrary.org/obo/CL:0000084