PubMed:22127321 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/22127321","sourcedb":"PubMed","sourceid":"22127321","source_url":"http://www.ncbi.nlm.nih.gov/pubmed/22127321","text":"Research and discovery of the first human cancer virus, HTLV-1.\nHuman T-cell lymphoma virus (HTLV)-1 was the first human retrovirus to be discovered. It has been recognized as the cause of adult T-cell leukemia (ATL). In addition to giving a historical perspective on HTLV-1 and other retrovirus research, this paper discusses the origin of HTLV-1; the modes of transmission and global epidemiology of HTLV-1 infection; the genome of HTLV-1 and the mechanism of HTLV-1-induced leukemogenesis; the role of HTLV-1 in other diseases, and recent breakthroughs in ATL therapy.","tracks":[{"project":"PubmedHPO","denotations":[{"id":"T1","span":{"begin":70,"end":85},"obj":"HP_0012190"},{"id":"T2","span":{"begin":77,"end":85},"obj":"HP_0002665"},{"id":"T3","span":{"begin":202,"end":210},"obj":"HP_0001909"}],"attributes":[{"subj":"T1","pred":"source","obj":"PubmedHPO"},{"subj":"T2","pred":"source","obj":"PubmedHPO"},{"subj":"T3","pred":"source","obj":"PubmedHPO"}]},{"project":"bionlp-st-cg-2013-training","denotations":[{"id":"T1","span":{"begin":36,"end":41},"obj":"Organism"},{"id":"T2","span":{"begin":42,"end":48},"obj":"Cancer"},{"id":"T3","span":{"begin":56,"end":62},"obj":"Organism"},{"id":"T4","span":{"begin":64,"end":100},"obj":"Organism"},{"id":"T5","span":{"begin":115,"end":120},"obj":"Organism"},{"id":"T6","span":{"begin":189,"end":210},"obj":"Cancer"},{"id":"T7","span":{"begin":212,"end":215},"obj":"Cancer"},{"id":"T8","span":{"begin":268,"end":274},"obj":"Organism"},{"id":"T9","span":{"begin":341,"end":347},"obj":"Organism"},{"id":"T10","span":{"begin":402,"end":408},"obj":"Organism"},{"id":"T11","span":{"begin":434,"end":440},"obj":"Organism"},{"id":"T12","span":{"begin":462,"end":468},"obj":"Organism"},{"id":"T13","span":{"begin":505,"end":511},"obj":"Organism"},{"id":"T14","span":{"begin":559,"end":562},"obj":"Cancer"}],"attributes":[{"subj":"T1","pred":"source","obj":"bionlp-st-cg-2013-training"},{"subj":"T2","pred":"source","obj":"bionlp-st-cg-2013-training"},{"subj":"T3","pred":"source","obj":"bionlp-st-cg-2013-training"},{"subj":"T4","pred":"source","obj":"bionlp-st-cg-2013-training"},{"subj":"T5","pred":"source","obj":"bionlp-st-cg-2013-training"},{"subj":"T6","pred":"source","obj":"bionlp-st-cg-2013-training"},{"subj":"T7","pred":"source","obj":"bionlp-st-cg-2013-training"},{"subj":"T8","pred":"source","obj":"bionlp-st-cg-2013-training"},{"subj":"T9","pred":"source","obj":"bionlp-st-cg-2013-training"},{"subj":"T10","pred":"source","obj":"bionlp-st-cg-2013-training"},{"subj":"T11","pred":"source","obj":"bionlp-st-cg-2013-training"},{"subj":"T12","pred":"source","obj":"bionlp-st-cg-2013-training"},{"subj":"T13","pred":"source","obj":"bionlp-st-cg-2013-training"},{"subj":"T14","pred":"source","obj":"bionlp-st-cg-2013-training"}]},{"project":"Allie","denotations":[{"id":"SS1_22127321_1_0","span":{"begin":64,"end":91},"obj":"expanded"},{"id":"SS2_22127321_1_0","span":{"begin":93,"end":97},"obj":"abbr"},{"id":"SS1_22127321_2_0","span":{"begin":189,"end":210},"obj":"expanded"},{"id":"SS2_22127321_2_0","span":{"begin":212,"end":215},"obj":"abbr"}],"relations":[{"id":"AE1_22127321_1_0","pred":"abbreviatedTo","subj":"SS1_22127321_1_0","obj":"SS2_22127321_1_0"},{"id":"AE1_22127321_2_0","pred":"abbreviatedTo","subj":"SS1_22127321_2_0","obj":"SS2_22127321_2_0"}],"attributes":[{"subj":"SS1_22127321_1_0","pred":"source","obj":"Allie"},{"subj":"SS2_22127321_1_0","pred":"source","obj":"Allie"},{"subj":"SS1_22127321_2_0","pred":"source","obj":"Allie"},{"subj":"SS2_22127321_2_0","pred":"source","obj":"Allie"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"PubmedHPO","color":"#ecdb93","default":true},{"id":"bionlp-st-cg-2013-training","color":"#c193ec"},{"id":"Allie","color":"#93eca6"}]}]}}