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GlyCosmos6-Glycan-Motif-Image

Id Subject Object Predicate Lexical cue image
T1 574-580 Glycan_Motif denotes core-1 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00031MO
T2 634-643 Glycan_Motif denotes T antigen https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00031MO
T3 711-717 Glycan_Motif denotes core-3 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00035MO
T4 941-951 Glycan_Motif denotes Tn antigen https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G57321FI
T5 994-1000 Glycan_Motif denotes core-3 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00035MO
T6 1022-1028 Glycan_Motif denotes Neu5Ac https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81533KY
T7 1193-1203 Glycan_Motif denotes Tn antigen https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G57321FI
T8 1563-1573 Glycan_Motif denotes Tn antigen https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G57321FI

sentences

Id Subject Object Predicate Lexical cue
T1 0-171 Sentence denotes α-N-acetylgalactosaminidase from infant-associated bifidobacteria belonging to novel glycoside hydrolase family 129 is implicated in alternative mucin degradation pathway.
T2 172-306 Sentence denotes Bifidobacteria inhabit the lower intestine of mammals including humans where the mucin gel layer forms a space for commensal bacteria.
T3 307-535 Sentence denotes We previously identified that infant-associated bifidobacteria possess an extracellular membrane-bound endo-α-N-acetylgalactosaminidase (EngBF) that may be involved in degradation and assimilation of mucin-type oligosaccharides.
T4 536-697 Sentence denotes However, EngBF is highly specific for core-1-type O-glycan (Galβ1-3GalNAcα1-Ser/Thr), also called T antigen, which is mainly attached onto gastroduodenal mucins.
T5 698-818 Sentence denotes By contrast, core-3-type O-glycans (GlcNAcβ1-3GalNAcα1-Ser/Thr) are predominantly found on the mucins in the intestines.
T6 819-971 Sentence denotes Here, we identified a novel α-N-acetylgalactosaminidase (NagBb) from Bifidobacterium bifidum JCM 1254 that hydrolyzes the Tn antigen (GalNAcα1-Ser/Thr).
T7 972-1401 Sentence denotes Sialyl and galactosyl core-3 (Galβ1-3/4GlcNAcβ1-3(Neu5Acα2-6)GalNAcα1-Ser/Thr), a major tetrasaccharide structure on MUC2 mucin primarily secreted from goblet cells in human sigmoid colon, can be serially hydrolyzed into Tn antigen by previously identified bifidobacterial extracellular glycosidases such as α-sialidase (SiaBb2), lacto-N-biosidase (LnbB), β-galactosidase (BbgIII), and β-N-acetylhexosaminidases (BbhI and BbhII).
T8 1402-1656 Sentence denotes Because NagBb is an intracellular enzyme without an N-terminal secretion signal sequence, it is likely involved in intracellular degradation and assimilation of Tn antigen-containing polypeptides, which might be incorporated through unknown transporters.
T9 1657-1778 Sentence denotes Thus, bifidobacteria possess two distinct pathways for assimilation of O-glycans on gastroduodenal and intestinal mucins.
T10 1779-1984 Sentence denotes NagBb homologs are conserved in infant-associated bifidobacteria, suggesting a significant role for their adaptation within the infant gut, and they were found to form a new glycoside hydrolase family 129.
T1 0-171 Sentence denotes α-N-acetylgalactosaminidase from infant-associated bifidobacteria belonging to novel glycoside hydrolase family 129 is implicated in alternative mucin degradation pathway.
T2 172-306 Sentence denotes Bifidobacteria inhabit the lower intestine of mammals including humans where the mucin gel layer forms a space for commensal bacteria.
T3 307-535 Sentence denotes We previously identified that infant-associated bifidobacteria possess an extracellular membrane-bound endo-α-N-acetylgalactosaminidase (EngBF) that may be involved in degradation and assimilation of mucin-type oligosaccharides.
T4 536-697 Sentence denotes However, EngBF is highly specific for core-1-type O-glycan (Galβ1-3GalNAcα1-Ser/Thr), also called T antigen, which is mainly attached onto gastroduodenal mucins.
T5 698-818 Sentence denotes By contrast, core-3-type O-glycans (GlcNAcβ1-3GalNAcα1-Ser/Thr) are predominantly found on the mucins in the intestines.
T6 819-971 Sentence denotes Here, we identified a novel α-N-acetylgalactosaminidase (NagBb) from Bifidobacterium bifidum JCM 1254 that hydrolyzes the Tn antigen (GalNAcα1-Ser/Thr).
T7 972-1401 Sentence denotes Sialyl and galactosyl core-3 (Galβ1-3/4GlcNAcβ1-3(Neu5Acα2-6)GalNAcα1-Ser/Thr), a major tetrasaccharide structure on MUC2 mucin primarily secreted from goblet cells in human sigmoid colon, can be serially hydrolyzed into Tn antigen by previously identified bifidobacterial extracellular glycosidases such as α-sialidase (SiaBb2), lacto-N-biosidase (LnbB), β-galactosidase (BbgIII), and β-N-acetylhexosaminidases (BbhI and BbhII).
T8 1402-1656 Sentence denotes Because NagBb is an intracellular enzyme without an N-terminal secretion signal sequence, it is likely involved in intracellular degradation and assimilation of Tn antigen-containing polypeptides, which might be incorporated through unknown transporters.
T9 1657-1778 Sentence denotes Thus, bifidobacteria possess two distinct pathways for assimilation of O-glycans on gastroduodenal and intestinal mucins.
T10 1779-1984 Sentence denotes NagBb homologs are conserved in infant-associated bifidobacteria, suggesting a significant role for their adaptation within the infant gut, and they were found to form a new glycoside hydrolase family 129.

GlyCosmos6-Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 574-580 https://glytoucan.org/Structures/Glycans/G00031MO denotes core-1
T2 634-643 https://glytoucan.org/Structures/Glycans/G00031MO denotes T antigen
T3 941-951 https://glytoucan.org/Structures/Glycans/G57321FI denotes Tn antigen
T4 1022-1028 https://glytoucan.org/Structures/Glycans/G81533KY denotes Neu5Ac
T5 1193-1203 https://glytoucan.org/Structures/Glycans/G57321FI denotes Tn antigen
T6 1563-1573 https://glytoucan.org/Structures/Glycans/G57321FI denotes Tn antigen

Glycosmos6-GlycoEpitope

Id Subject Object Predicate Lexical cue
T1 634-643 http://www.glycoepitope.jp/epitopes/EP0020 denotes T antigen
T2 941-951 http://www.glycoepitope.jp/epitopes/EP0021 denotes Tn antigen
T3 1193-1203 http://www.glycoepitope.jp/epitopes/EP0021 denotes Tn antigen
T4 1563-1573 http://www.glycoepitope.jp/epitopes/EP0021 denotes Tn antigen

Glycosmos6-MAT

Id Subject Object Predicate Lexical cue
T1 205-214 http://purl.obolibrary.org/obo/MAT_0000043 denotes intestine
T2 807-817 http://purl.obolibrary.org/obo/MAT_0000043 denotes intestines
T3 1146-1159 http://purl.obolibrary.org/obo/MAT_0000314 denotes sigmoid colon
T4 1154-1159 http://purl.obolibrary.org/obo/MAT_0000526 denotes colon
T5 1760-1770 http://purl.obolibrary.org/obo/MAT_0000043 denotes intestinal
T6 1914-1917 http://purl.obolibrary.org/obo/MAT_0000043 denotes gut

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 205-214 Body_part denotes intestine http://purl.obolibrary.org/obo/MAT_0000043
T2 807-817 Body_part denotes intestines http://purl.obolibrary.org/obo/MAT_0000043
T3 1146-1159 Body_part denotes sigmoid colon http://purl.obolibrary.org/obo/MAT_0000314
T4 1760-1770 Body_part denotes intestinal http://purl.obolibrary.org/obo/MAT_0000043
T5 1914-1917 Body_part denotes gut http://purl.obolibrary.org/obo/MAT_0000043

Glycan-GlyCosmos

Id Subject Object Predicate Lexical cue image
T1 603-609 Glycan denotes GalNAc https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL
T2 634-643 Glycan denotes T antigen https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO
T3 744-750 Glycan denotes GalNAc https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL
T4 941-951 Glycan denotes Tn antigen https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI
T5 953-959 Glycan denotes GalNAc https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL
T6 1022-1028 Glycan denotes Neu5Ac https://api.glycosmos.org/wurcs2image/latest/png/binary/G76685HR
T7 1033-1039 Glycan denotes GalNAc https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL
T8 1193-1203 Glycan denotes Tn antigen https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI
T9 1563-1573 Glycan denotes Tn antigen https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI

GlyCosmos-GlycoEpitope

Id Subject Object Predicate Lexical cue glycoepitope_id
T1 634-643 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes T antigen http://www.glycoepitope.jp/epitopes/EP0020
T2 941-951 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn antigen http://www.glycoepitope.jp/epitopes/EP0021
T3 1193-1203 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn antigen http://www.glycoepitope.jp/epitopes/EP0021
T4 1563-1573 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn antigen http://www.glycoepitope.jp/epitopes/EP0021

GlyCosmos15-NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 297-305 OrganismTaxon denotes bacteria 2|629395
T3 888-911 OrganismTaxon denotes Bifidobacterium bifidum 1681
T4 1140-1145 OrganismTaxon denotes human 9606

GlyCosmos15-CL

Id Subject Object Predicate Lexical cue cl_id
T1 1124-1136 Cell denotes goblet cells http://purl.obolibrary.org/obo/CL:0000160

GlyCosmos15-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 199-214 Body_part denotes lower intestine http://purl.obolibrary.org/obo/UBERON_0002116
T2 263-268 Body_part denotes layer http://purl.obolibrary.org/obo/UBERON_0000119|http://purl.obolibrary.org/obo/UBERON_0022303
T4 277-282 Body_part denotes space http://purl.obolibrary.org/obo/UBERON_0000464
T5 381-394 Body_part denotes extracellular http://purl.obolibrary.org/obo/GO_0005576
T6 395-403 Body_part denotes membrane http://purl.obolibrary.org/obo/GO_0016020|http://purl.obolibrary.org/obo/UBERON_0000094|http://purl.obolibrary.org/obo/UBERON_0000158
T9 807-817 Body_part denotes intestines http://purl.obolibrary.org/obo/UBERON_0000160
T10 1124-1136 Body_part denotes goblet cells http://purl.obolibrary.org/obo/CL_0000160
T11 1146-1159 Body_part denotes sigmoid colon http://purl.obolibrary.org/obo/UBERON_0001159
T12 1245-1258 Body_part denotes extracellular http://purl.obolibrary.org/obo/GO_0005576
T13 1422-1435 Body_part denotes intracellular http://purl.obolibrary.org/obo/GO_0005622
T14 1517-1530 Body_part denotes intracellular http://purl.obolibrary.org/obo/GO_0005622
T15 1914-1917 Body_part denotes gut http://purl.obolibrary.org/obo/UBERON_0001007|http://purl.obolibrary.org/obo/UBERON_0001555|http://purl.obolibrary.org/obo/UBERON_0004907

GlyCosmos15-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 205-214 Body_part denotes intestine http://purl.obolibrary.org/obo/MAT_0000043
T2 807-817 Body_part denotes intestines http://purl.obolibrary.org/obo/MAT_0000043
T3 1146-1159 Body_part denotes sigmoid colon http://purl.obolibrary.org/obo/MAT_0000314
T4 1760-1770 Body_part denotes intestinal http://purl.obolibrary.org/obo/MAT_0000043
T5 1914-1917 Body_part denotes gut http://purl.obolibrary.org/obo/MAT_0000043

sentences

Id Subject Object Predicate Lexical cue
T1 0-171 Sentence denotes α-N-acetylgalactosaminidase from infant-associated bifidobacteria belonging to novel glycoside hydrolase family 129 is implicated in alternative mucin degradation pathway.
T2 172-306 Sentence denotes Bifidobacteria inhabit the lower intestine of mammals including humans where the mucin gel layer forms a space for commensal bacteria.
T3 307-535 Sentence denotes We previously identified that infant-associated bifidobacteria possess an extracellular membrane-bound endo-α-N-acetylgalactosaminidase (EngBF) that may be involved in degradation and assimilation of mucin-type oligosaccharides.
T4 536-697 Sentence denotes However, EngBF is highly specific for core-1-type O-glycan (Galβ1-3GalNAcα1-Ser/Thr), also called T antigen, which is mainly attached onto gastroduodenal mucins.
T5 698-818 Sentence denotes By contrast, core-3-type O-glycans (GlcNAcβ1-3GalNAcα1-Ser/Thr) are predominantly found on the mucins in the intestines.
T6 819-971 Sentence denotes Here, we identified a novel α-N-acetylgalactosaminidase (NagBb) from Bifidobacterium bifidum JCM 1254 that hydrolyzes the Tn antigen (GalNAcα1-Ser/Thr).
T7 972-1401 Sentence denotes Sialyl and galactosyl core-3 (Galβ1-3/4GlcNAcβ1-3(Neu5Acα2-6)GalNAcα1-Ser/Thr), a major tetrasaccharide structure on MUC2 mucin primarily secreted from goblet cells in human sigmoid colon, can be serially hydrolyzed into Tn antigen by previously identified bifidobacterial extracellular glycosidases such as α-sialidase (SiaBb2), lacto-N-biosidase (LnbB), β-galactosidase (BbgIII), and β-N-acetylhexosaminidases (BbhI and BbhII).
T8 1402-1656 Sentence denotes Because NagBb is an intracellular enzyme without an N-terminal secretion signal sequence, it is likely involved in intracellular degradation and assimilation of Tn antigen-containing polypeptides, which might be incorporated through unknown transporters.
T9 1657-1778 Sentence denotes Thus, bifidobacteria possess two distinct pathways for assimilation of O-glycans on gastroduodenal and intestinal mucins.
T10 1779-1984 Sentence denotes NagBb homologs are conserved in infant-associated bifidobacteria, suggesting a significant role for their adaptation within the infant gut, and they were found to form a new glycoside hydrolase family 129.
T1 0-171 Sentence denotes α-N-acetylgalactosaminidase from infant-associated bifidobacteria belonging to novel glycoside hydrolase family 129 is implicated in alternative mucin degradation pathway.
T2 172-306 Sentence denotes Bifidobacteria inhabit the lower intestine of mammals including humans where the mucin gel layer forms a space for commensal bacteria.
T3 307-535 Sentence denotes We previously identified that infant-associated bifidobacteria possess an extracellular membrane-bound endo-α-N-acetylgalactosaminidase (EngBF) that may be involved in degradation and assimilation of mucin-type oligosaccharides.
T4 536-697 Sentence denotes However, EngBF is highly specific for core-1-type O-glycan (Galβ1-3GalNAcα1-Ser/Thr), also called T antigen, which is mainly attached onto gastroduodenal mucins.
T5 698-818 Sentence denotes By contrast, core-3-type O-glycans (GlcNAcβ1-3GalNAcα1-Ser/Thr) are predominantly found on the mucins in the intestines.
T6 819-971 Sentence denotes Here, we identified a novel α-N-acetylgalactosaminidase (NagBb) from Bifidobacterium bifidum JCM 1254 that hydrolyzes the Tn antigen (GalNAcα1-Ser/Thr).
T7 972-1401 Sentence denotes Sialyl and galactosyl core-3 (Galβ1-3/4GlcNAcβ1-3(Neu5Acα2-6)GalNAcα1-Ser/Thr), a major tetrasaccharide structure on MUC2 mucin primarily secreted from goblet cells in human sigmoid colon, can be serially hydrolyzed into Tn antigen by previously identified bifidobacterial extracellular glycosidases such as α-sialidase (SiaBb2), lacto-N-biosidase (LnbB), β-galactosidase (BbgIII), and β-N-acetylhexosaminidases (BbhI and BbhII).
T8 1402-1656 Sentence denotes Because NagBb is an intracellular enzyme without an N-terminal secretion signal sequence, it is likely involved in intracellular degradation and assimilation of Tn antigen-containing polypeptides, which might be incorporated through unknown transporters.
T9 1657-1778 Sentence denotes Thus, bifidobacteria possess two distinct pathways for assimilation of O-glycans on gastroduodenal and intestinal mucins.
T10 1779-1984 Sentence denotes NagBb homologs are conserved in infant-associated bifidobacteria, suggesting a significant role for their adaptation within the infant gut, and they were found to form a new glycoside hydrolase family 129.

GlyCosmos15-Sentences

Id Subject Object Predicate Lexical cue
T1 0-171 Sentence denotes α-N-acetylgalactosaminidase from infant-associated bifidobacteria belonging to novel glycoside hydrolase family 129 is implicated in alternative mucin degradation pathway.
T2 172-306 Sentence denotes Bifidobacteria inhabit the lower intestine of mammals including humans where the mucin gel layer forms a space for commensal bacteria.
T3 307-535 Sentence denotes We previously identified that infant-associated bifidobacteria possess an extracellular membrane-bound endo-α-N-acetylgalactosaminidase (EngBF) that may be involved in degradation and assimilation of mucin-type oligosaccharides.
T4 536-697 Sentence denotes However, EngBF is highly specific for core-1-type O-glycan (Galβ1-3GalNAcα1-Ser/Thr), also called T antigen, which is mainly attached onto gastroduodenal mucins.
T5 698-818 Sentence denotes By contrast, core-3-type O-glycans (GlcNAcβ1-3GalNAcα1-Ser/Thr) are predominantly found on the mucins in the intestines.
T6 819-971 Sentence denotes Here, we identified a novel α-N-acetylgalactosaminidase (NagBb) from Bifidobacterium bifidum JCM 1254 that hydrolyzes the Tn antigen (GalNAcα1-Ser/Thr).
T7 972-1401 Sentence denotes Sialyl and galactosyl core-3 (Galβ1-3/4GlcNAcβ1-3(Neu5Acα2-6)GalNAcα1-Ser/Thr), a major tetrasaccharide structure on MUC2 mucin primarily secreted from goblet cells in human sigmoid colon, can be serially hydrolyzed into Tn antigen by previously identified bifidobacterial extracellular glycosidases such as α-sialidase (SiaBb2), lacto-N-biosidase (LnbB), β-galactosidase (BbgIII), and β-N-acetylhexosaminidases (BbhI and BbhII).
T8 1402-1656 Sentence denotes Because NagBb is an intracellular enzyme without an N-terminal secretion signal sequence, it is likely involved in intracellular degradation and assimilation of Tn antigen-containing polypeptides, which might be incorporated through unknown transporters.
T9 1657-1778 Sentence denotes Thus, bifidobacteria possess two distinct pathways for assimilation of O-glycans on gastroduodenal and intestinal mucins.
T10 1779-1984 Sentence denotes NagBb homologs are conserved in infant-associated bifidobacteria, suggesting a significant role for their adaptation within the infant gut, and they were found to form a new glycoside hydrolase family 129.

GlyCosmos15-Glycan

Id Subject Object Predicate Lexical cue image
T1 603-609 Glycan denotes GalNAc https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL
T2 634-643 Glycan denotes T antigen https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO
T3 744-750 Glycan denotes GalNAc https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL
T4 941-951 Glycan denotes Tn antigen https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI
T5 953-959 Glycan denotes GalNAc https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL
T6 1022-1028 Glycan denotes Neu5Ac https://api.glycosmos.org/wurcs2image/latest/png/binary/G76685HR
T7 1033-1039 Glycan denotes GalNAc https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL
T8 1193-1203 Glycan denotes Tn antigen https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI
T9 1563-1573 Glycan denotes Tn antigen https://api.glycosmos.org/wurcs2image/latest/png/binary/G57321FI

GlyCosmos15-GlycoEpitope

Id Subject Object Predicate Lexical cue glycoepitope_id
T1 634-643 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes T antigen http://www.glycoepitope.jp/epitopes/EP0020
T2 941-951 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn antigen http://www.glycoepitope.jp/epitopes/EP0021
T3 1193-1203 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn antigen http://www.glycoepitope.jp/epitopes/EP0021
T4 1563-1573 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Tn antigen http://www.glycoepitope.jp/epitopes/EP0021

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 297-305 OrganismTaxon denotes bacteria 2|629395
T3 888-911 OrganismTaxon denotes Bifidobacterium bifidum 1681
T4 1140-1145 OrganismTaxon denotes human 9606

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 199-214 Body_part denotes lower intestine http://purl.obolibrary.org/obo/UBERON_0002116
T2 263-268 Body_part denotes layer http://purl.obolibrary.org/obo/UBERON_0000119|http://purl.obolibrary.org/obo/UBERON_0022303
T4 277-282 Body_part denotes space http://purl.obolibrary.org/obo/UBERON_0000464
T5 381-394 Body_part denotes extracellular http://purl.obolibrary.org/obo/GO_0005576
T6 395-403 Body_part denotes membrane http://purl.obolibrary.org/obo/GO_0016020|http://purl.obolibrary.org/obo/UBERON_0000094|http://purl.obolibrary.org/obo/UBERON_0000158
T9 807-817 Body_part denotes intestines http://purl.obolibrary.org/obo/UBERON_0000160
T10 1124-1136 Body_part denotes goblet cells http://purl.obolibrary.org/obo/CL_0000160
T11 1146-1159 Body_part denotes sigmoid colon http://purl.obolibrary.org/obo/UBERON_0001159
T12 1245-1258 Body_part denotes extracellular http://purl.obolibrary.org/obo/GO_0005576
T13 1422-1435 Body_part denotes intracellular http://purl.obolibrary.org/obo/GO_0005622
T14 1517-1530 Body_part denotes intracellular http://purl.obolibrary.org/obo/GO_0005622
T15 1914-1917 Body_part denotes gut http://purl.obolibrary.org/obo/UBERON_0001007|http://purl.obolibrary.org/obo/UBERON_0001555|http://purl.obolibrary.org/obo/UBERON_0004907

CL-cell

Id Subject Object Predicate Lexical cue cl_id
T1 1124-1136 Cell denotes goblet cells http://purl.obolibrary.org/obo/CL:0000160