> top > docs > PubMed:22051099 > annotations

PubMed:22051099 JSONTXT

Annnotations TAB JSON ListView MergeView

LitCoin-sentences

Id Subject Object Predicate Lexical cue
T1 0-99 Sentence denotes Variation in the CXCR1 gene (IL8RA) is not associated with susceptibility to chronic periodontitis.
T2 100-111 Sentence denotes BACKGROUND:
T3 112-309 Sentence denotes The chemokine receptor 1 CXCR-1 (or IL8R-alpha) is a specific receptor for the interleukin 8 (IL-8), which is chemoattractant for neutrophils and has an important role in the inflammatory response.
T4 310-432 Sentence denotes The polymorphism rs2234671 at position Ex2+860G>C of the CXCR1 gene causes a conservative amino acid substitution (S276T).
T5 433-552 Sentence denotes This single nucleotide polymorphism (SNP) seemed to be functional as it was associated with decreased lung cancer risk.
T6 553-703 Sentence denotes Previous studies of our group found association of haplotypes in the IL8 and in the CXCR2 genes with the multifactorial disease chronic periodontitis.
T7 704-826 Sentence denotes In this study we investigated the polymorphism rs2234671 in 395 Brazilian subjects with and without chronic periodontitis.
T8 827-836 Sentence denotes FINDINGS:
T9 837-941 Sentence denotes Similar distribution of the allelic and genotypic frequencies were observed between the groups (p>0.05).
T10 942-954 Sentence denotes CONCLUSIONS:
T11 955-1104 Sentence denotes The polymorphism rs2234671 in the CXCR1 gene was not associated with the susceptibility to chronic periodontitis in the studied Brazilian population.

LitCoin-entities

Id Subject Object Predicate Lexical cue db_id
8954 17-22 GeneOrGeneProduct denotes CXCR1 NCBIGene:3577
8955 29-34 GeneOrGeneProduct denotes IL8RA NCBIGene:3577
8956 77-98 DiseaseOrPhenotypicFeature denotes chronic periodontitis MESH:D055113
8957 116-143 GeneOrGeneProduct denotes chemokine receptor 1 CXCR-1 NCBIGene:3577
8958 148-158 GeneOrGeneProduct denotes IL8R-alpha NCBIGene:3577
8959 191-204 GeneOrGeneProduct denotes interleukin 8 NCBIGene:3576
8960 206-210 GeneOrGeneProduct denotes IL-8 NCBIGene:3576
8961 287-299 DiseaseOrPhenotypicFeature denotes inflammatory MESH:D007249
8962 327-336 SequenceVariant denotes rs2234671 DBSNP:rs2234671
8963 349-359 SequenceVariant denotes Ex2+860G>C DBSNP:rs2234671
8964 367-372 GeneOrGeneProduct denotes CXCR1 NCBIGene:3577
8965 425-430 SequenceVariant denotes S276T DBSNP:rs2234671
8966 535-546 DiseaseOrPhenotypicFeature denotes lung cancer MESH:D008175
8967 622-625 GeneOrGeneProduct denotes IL8 NCBIGene:3576
8968 637-642 GeneOrGeneProduct denotes CXCR2 NCBIGene:3579
8969 681-702 DiseaseOrPhenotypicFeature denotes chronic periodontitis MESH:D055113
8970 751-760 SequenceVariant denotes rs2234671 DBSNP:rs2234671
8971 804-825 DiseaseOrPhenotypicFeature denotes chronic periodontitis MESH:D055113
8972 972-981 SequenceVariant denotes rs2234671 DBSNP:rs2234671
8973 989-994 GeneOrGeneProduct denotes CXCR1 NCBIGene:3577
8974 1046-1067 DiseaseOrPhenotypicFeature denotes chronic periodontitis MESH:D055113

LitCoin_Mondo

Id Subject Object Predicate Lexical cue mondo_id
T1 77-98 DiseaseOrPhenotypicFeature denotes chronic periodontitis 0005593
T2 85-98 DiseaseOrPhenotypicFeature denotes periodontitis 0005076
T3 535-546 DiseaseOrPhenotypicFeature denotes lung cancer 0008903
T4 540-546 DiseaseOrPhenotypicFeature denotes cancer 0004992
T5 681-702 DiseaseOrPhenotypicFeature denotes chronic periodontitis 0005593
T6 689-702 DiseaseOrPhenotypicFeature denotes periodontitis 0005076
T7 804-825 DiseaseOrPhenotypicFeature denotes chronic periodontitis 0005593
T8 812-825 DiseaseOrPhenotypicFeature denotes periodontitis 0005076
T9 1046-1067 DiseaseOrPhenotypicFeature denotes chronic periodontitis 0005593
T10 1054-1067 DiseaseOrPhenotypicFeature denotes periodontitis 0005076

LitCoin-SeqVar

Id Subject Object Predicate Lexical cue
T1 327-336 SequenceVariant denotes rs2234671
T2 353-357 SequenceVariant denotes 860G
T3 425-430 SequenceVariant denotes S276T
T4 751-760 SequenceVariant denotes rs2234671
T5 972-981 SequenceVariant denotes rs2234671

LitCoin-GeneOrGeneProduct-v0

Id Subject Object Predicate Lexical cue
T1 17-22 GeneOrGeneProduct denotes CXCR1
T2 29-34 GeneOrGeneProduct denotes IL8RA
T3 116-136 GeneOrGeneProduct denotes chemokine receptor 1
T4 137-143 GeneOrGeneProduct denotes CXCR-1
T5 148-152 GeneOrGeneProduct denotes IL8R
T6 153-158 GeneOrGeneProduct denotes alpha
T7 174-182 GeneOrGeneProduct denotes receptor
T8 191-204 GeneOrGeneProduct denotes interleukin 8
T9 206-210 GeneOrGeneProduct denotes IL-8
T10 367-372 GeneOrGeneProduct denotes CXCR1
T11 387-399 GeneOrGeneProduct denotes conservative
T12 400-410 GeneOrGeneProduct denotes amino acid
T13 535-539 GeneOrGeneProduct denotes lung
T14 622-625 GeneOrGeneProduct denotes IL8
T15 637-642 GeneOrGeneProduct denotes CXCR2
T16 827-835 GeneOrGeneProduct denotes FINDINGS
T17 837-844 GeneOrGeneProduct denotes Similar
T18 887-898 GeneOrGeneProduct denotes frequencies
T19 989-994 GeneOrGeneProduct denotes CXCR1

LitCoin-GeneOrGeneProduct-v2

Id Subject Object Predicate Lexical cue
T1 17-22 GeneOrGeneProduct denotes CXCR1
T2 29-34 GeneOrGeneProduct denotes IL8RA
T3 116-136 GeneOrGeneProduct denotes chemokine receptor 1
T4 137-143 GeneOrGeneProduct denotes CXCR-1
T5 148-152 GeneOrGeneProduct denotes IL8R
T6 153-158 GeneOrGeneProduct denotes alpha
T7 174-182 GeneOrGeneProduct denotes receptor
T8 191-204 GeneOrGeneProduct denotes interleukin 8
T9 206-210 GeneOrGeneProduct denotes IL-8
T10 367-372 GeneOrGeneProduct denotes CXCR1
T11 400-410 GeneOrGeneProduct denotes amino acid
T12 622-625 GeneOrGeneProduct denotes IL8
T13 637-642 GeneOrGeneProduct denotes CXCR2
T14 837-844 GeneOrGeneProduct denotes Similar
T15 989-994 GeneOrGeneProduct denotes CXCR1

LitCoin-Disease-MeSH

Id Subject Object Predicate Lexical cue originalLabel
T1 77-98 DiseaseOrPhenotypicFeature denotes chronic periodontitis D055113
T2 287-299 DiseaseOrPhenotypicFeature denotes inflammatory DISEASE
T3 535-546 DiseaseOrPhenotypicFeature denotes lung cancer D008175
T4 673-680 DiseaseOrPhenotypicFeature denotes disease D004194
T5 681-702 DiseaseOrPhenotypicFeature denotes chronic periodontitis D055113
T6 804-825 DiseaseOrPhenotypicFeature denotes chronic periodontitis D055113
T7 1046-1067 DiseaseOrPhenotypicFeature denotes chronic periodontitis D055113

LitCoin-GeneOrGeneProduct-v3

Id Subject Object Predicate Lexical cue
T1 17-22 GeneOrGeneProduct denotes CXCR1
T2 29-34 GeneOrGeneProduct denotes IL8RA
T3 116-136 GeneOrGeneProduct denotes chemokine receptor 1
T4 137-143 GeneOrGeneProduct denotes CXCR-1
T5 148-152 GeneOrGeneProduct denotes IL8R
T6 153-158 GeneOrGeneProduct denotes alpha
T7 191-204 GeneOrGeneProduct denotes interleukin 8
T8 206-210 GeneOrGeneProduct denotes IL-8
T9 367-372 GeneOrGeneProduct denotes CXCR1
T10 622-625 GeneOrGeneProduct denotes IL8
T11 637-642 GeneOrGeneProduct denotes CXCR2
T12 989-994 GeneOrGeneProduct denotes CXCR1

LitCoin_Mondo_095

Id Subject Object Predicate Lexical cue mondo_id
T1 77-98 DiseaseOrPhenotypicFeature denotes chronic periodontitis 0005593
T2 535-546 DiseaseOrPhenotypicFeature denotes lung cancer 0008903|0005138
T4 681-702 DiseaseOrPhenotypicFeature denotes chronic periodontitis 0005593
T5 804-825 DiseaseOrPhenotypicFeature denotes chronic periodontitis 0005593
T6 1046-1067 DiseaseOrPhenotypicFeature denotes chronic periodontitis 0005593

LitCoin-MeSH-Disease-2

Id Subject Object Predicate Lexical cue ID:
T1 77-98 DiseaseOrPhenotypicFeature denotes chronic periodontitis D055113
T2 287-299 DiseaseOrPhenotypicFeature denotes inflammatory DISEASE
T3 535-546 DiseaseOrPhenotypicFeature denotes lung cancer D008175
T4 673-680 DiseaseOrPhenotypicFeature denotes disease D004194
T5 681-702 DiseaseOrPhenotypicFeature denotes chronic periodontitis D055113
T6 804-825 DiseaseOrPhenotypicFeature denotes chronic periodontitis D055113
T7 1046-1067 DiseaseOrPhenotypicFeature denotes chronic periodontitis D055113

LitCoin-MONDO_bioort2019

Id Subject Object Predicate Lexical cue #label
T1 77-98 DiseaseOrPhenotypicFeature denotes chronic periodontitis D055113
T2 535-546 DiseaseOrPhenotypicFeature denotes lung cancer D008175
T3 681-702 DiseaseOrPhenotypicFeature denotes chronic periodontitis D055113
T4 804-825 DiseaseOrPhenotypicFeature denotes chronic periodontitis D055113
T5 1046-1067 DiseaseOrPhenotypicFeature denotes chronic periodontitis D055113

LitCoin-Chemical-MeSH-CHEBI

Id Subject Object Predicate Lexical cue ID:
T1 191-204 ChemicalEntity denotes interleukin 8 http://purl.obolibrary.org/obo/CHEBI_138181
T2 222-237 ChemicalEntity denotes chemoattractant D002630
T3 622-625 ChemicalEntity denotes IL8 http://purl.obolibrary.org/obo/CHEBI_138181

LitCoin-training-merged

Id Subject Object Predicate Lexical cue #label ID:
T3 622-625 ChemicalEntity denotes IL8 http://purl.obolibrary.org/obo/CHEBI_138181
T2 222-237 ChemicalEntity denotes chemoattractant D002630
T1 191-204 ChemicalEntity denotes interleukin 8 http://purl.obolibrary.org/obo/CHEBI_138181
T12 989-994 GeneOrGeneProduct denotes CXCR1
T11 637-642 GeneOrGeneProduct denotes CXCR2
T10 622-625 GeneOrGeneProduct denotes IL8
T9 367-372 GeneOrGeneProduct denotes CXCR1
T8 206-210 GeneOrGeneProduct denotes IL-8
T7 191-204 GeneOrGeneProduct denotes interleukin 8
T6 153-158 GeneOrGeneProduct denotes alpha
T5 148-152 GeneOrGeneProduct denotes IL8R
T4 137-143 GeneOrGeneProduct denotes CXCR-1
T45003 116-136 GeneOrGeneProduct denotes chemokine receptor 1
T59464 29-34 GeneOrGeneProduct denotes IL8RA
T75924 17-22 GeneOrGeneProduct denotes CXCR1
T26163 1046-1067 DiseaseOrPhenotypicFeature denotes chronic periodontitis D055113
T22175 804-825 DiseaseOrPhenotypicFeature denotes chronic periodontitis D055113
T42114 681-702 DiseaseOrPhenotypicFeature denotes chronic periodontitis D055113
T52598 535-546 DiseaseOrPhenotypicFeature denotes lung cancer D008175
T24677 77-98 DiseaseOrPhenotypicFeature denotes chronic periodontitis D055113
T28470 972-981 SequenceVariant denotes rs2234671
T54972 751-760 SequenceVariant denotes rs2234671
T99279 425-430 SequenceVariant denotes S276T
T91172 353-357 SequenceVariant denotes 860G
T66463 327-336 SequenceVariant denotes rs2234671

Inflammaging

Id Subject Object Predicate Lexical cue
T1 0-99 Sentence denotes Variation in the CXCR1 gene (IL8RA) is not associated with susceptibility to chronic periodontitis.
T2 100-111 Sentence denotes BACKGROUND:
T3 112-309 Sentence denotes The chemokine receptor 1 CXCR-1 (or IL8R-alpha) is a specific receptor for the interleukin 8 (IL-8), which is chemoattractant for neutrophils and has an important role in the inflammatory response.
T4 310-432 Sentence denotes The polymorphism rs2234671 at position Ex2+860G>C of the CXCR1 gene causes a conservative amino acid substitution (S276T).
T5 433-552 Sentence denotes This single nucleotide polymorphism (SNP) seemed to be functional as it was associated with decreased lung cancer risk.
T6 553-703 Sentence denotes Previous studies of our group found association of haplotypes in the IL8 and in the CXCR2 genes with the multifactorial disease chronic periodontitis.
T7 704-826 Sentence denotes In this study we investigated the polymorphism rs2234671 in 395 Brazilian subjects with and without chronic periodontitis.
T8 827-836 Sentence denotes FINDINGS:
T9 837-941 Sentence denotes Similar distribution of the allelic and genotypic frequencies were observed between the groups (p>0.05).
T10 942-954 Sentence denotes CONCLUSIONS:
T11 955-1104 Sentence denotes The polymorphism rs2234671 in the CXCR1 gene was not associated with the susceptibility to chronic periodontitis in the studied Brazilian population.
T1 0-99 Sentence denotes Variation in the CXCR1 gene (IL8RA) is not associated with susceptibility to chronic periodontitis.
T2 100-111 Sentence denotes BACKGROUND:
T3 112-309 Sentence denotes The chemokine receptor 1 CXCR-1 (or IL8R-alpha) is a specific receptor for the interleukin 8 (IL-8), which is chemoattractant for neutrophils and has an important role in the inflammatory response.
T4 310-432 Sentence denotes The polymorphism rs2234671 at position Ex2+860G>C of the CXCR1 gene causes a conservative amino acid substitution (S276T).
T5 433-552 Sentence denotes This single nucleotide polymorphism (SNP) seemed to be functional as it was associated with decreased lung cancer risk.
T6 553-703 Sentence denotes Previous studies of our group found association of haplotypes in the IL8 and in the CXCR2 genes with the multifactorial disease chronic periodontitis.
T7 704-826 Sentence denotes In this study we investigated the polymorphism rs2234671 in 395 Brazilian subjects with and without chronic periodontitis.
T8 827-836 Sentence denotes FINDINGS:
T9 837-941 Sentence denotes Similar distribution of the allelic and genotypic frequencies were observed between the groups (p>0.05).
T10 942-954 Sentence denotes CONCLUSIONS:
T11 955-1104 Sentence denotes The polymorphism rs2234671 in the CXCR1 gene was not associated with the susceptibility to chronic periodontitis in the studied Brazilian population.

DisGeNET

Id Subject Object Predicate Lexical cue
T0 29-34 gene:3577 denotes IL8RA
T1 77-98 disease:C0266929 denotes chronic periodontitis
T2 17-22 gene:3577 denotes CXCR1
T3 77-98 disease:C0266929 denotes chronic periodontitis
T4 637-642 gene:3579 denotes CXCR2
T5 673-702 disease:C0008679 denotes disease chronic periodontitis
T6 637-642 gene:3579 denotes CXCR2
T7 673-702 disease:C0266929 denotes disease chronic periodontitis
T8 622-625 gene:3576 denotes IL8
T9 673-702 disease:C0266929 denotes disease chronic periodontitis
T10 622-625 gene:3576 denotes IL8
T11 673-702 disease:C0008679 denotes disease chronic periodontitis
T12 989-994 gene:3577 denotes CXCR1
T13 1046-1067 disease:C0266929 denotes chronic periodontitis
R1 T0 T1 associated_with IL8RA,chronic periodontitis
R2 T2 T3 associated_with CXCR1,chronic periodontitis
R3 T4 T5 associated_with CXCR2,disease chronic periodontitis
R4 T6 T7 associated_with CXCR2,disease chronic periodontitis
R5 T8 T9 associated_with IL8,disease chronic periodontitis
R6 T10 T11 associated_with IL8,disease chronic periodontitis
R7 T12 T13 associated_with CXCR1,chronic periodontitis

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 535-546 HP_0100526 denotes lung cancer
T2 540-546 HP_0002664 denotes cancer

Allie

Id Subject Object Predicate Lexical cue
SS1_22051099_2_0 191-204 expanded denotes interleukin 8
SS2_22051099_2_0 206-210 abbr denotes IL-8
SS1_22051099_4_0 438-468 expanded denotes single nucleotide polymorphism
SS2_22051099_4_0 470-473 abbr denotes SNP
AE1_22051099_2_0 SS1_22051099_2_0 SS2_22051099_2_0 abbreviatedTo interleukin 8,IL-8
AE1_22051099_4_0 SS1_22051099_4_0 SS2_22051099_4_0 abbreviatedTo single nucleotide polymorphism,SNP

tmVarCorpus

Id Subject Object Predicate Lexical cue
T1 327-336 SNP:rs2234671 denotes rs2234671
T2 349-359 DNAMutation:c|SUB|G|Ex2+860|C denotes Ex2+860G>C
T3 425-430 ProteinMutation:p|SUB|S|276|T denotes S276T
T4 751-760 SNP:rs2234671 denotes rs2234671
T5 972-981 SNP:rs2234671 denotes rs2234671