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PubMed:2196279 JSONTXT

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DisGeNET

Id Subject Object Predicate Lexical cue
T0 133-143 gene:3630 denotes proinsulin
T1 37-56 disease:C0342283 denotes hyperproinsulinemia
R1 T0 T1 associated_with proinsulin,hyperproinsulinemia

DisGeNET5_gene_disease

Id Subject Object Predicate Lexical cue
2196279-0#133#143#gene3630 133-143 gene3630 denotes proinsulin
2196279-0#37#56#diseaseC0342283 37-56 diseaseC0342283 denotes hyperproinsulinemia
133#143#gene363037#56#diseaseC0342283 2196279-0#133#143#gene3630 2196279-0#37#56#diseaseC0342283 associated_with proinsulin,hyperproinsulinemia

sonoma

Id Subject Object Predicate Lexical cue
T-0 28-56 DISEASE denotes familial hyperproinsulinemia
T-1 57-60 REG denotes due
T-2 61-63 REG denotes to
T-3 66-74 VAR denotes mutation
T-4 133-143 GENE denotes proinsulin
T-5 176-184 VAR denotes mutation
T-6 279-288 VAR denotes Mutations
T-7 296-303 GENE denotes insulin
T-8 313-319 NEGREG denotes impair
T-9 324-335 MPA denotes bioactivity
T-10 343-350 GENE denotes insulin
T-11 388-397 VAR denotes mutations
T-12 408-418 REG denotes identified
T-13 434-440 NEGREG denotes impair
T-14 441-469 MPA denotes posttranslational processing
T-15 473-483 GENE denotes proinsulin
T-16 487-494 GENE denotes insulin
T-17 514-519 REG denotes alter
T-18 524-533 MPA denotes structure
T-19 541-548 GENE denotes insulin
T-20 567-575 NEGREG denotes reducing
T-21 580-588 INTERACTION denotes affinity
T-22 613-629 GENE denotes insulin receptor
T-23 706-715 VAR denotes mutations
T-24 721-728 NEGREG denotes inhibit
T-25 733-743 MPA denotes conversion
T-26 747-757 GENE denotes proinsulin
T-27 761-768 GENE denotes insulin
T-28 921-929 VAR denotes mutation
T-29 930-940 REG denotes converting
T-30 958-966 VAR denotes arginine
T-31 968-971 VAR denotes CGT
T-32 978-987 VAR denotes histidine
T-33 989-992 VAR denotes CAT
T-34 1009-1014 VAR denotes Arg65
T-35 1068-1088 MPA denotes proteolytic cleavage
T-36 1101-1108 GENE denotes insulin
T-37 1137-1145 VAR denotes mutation
T-38 1146-1154 REG denotes explains
T-39 1159-1169 NEGREG denotes impairment
T-40 1177-1185 MPA denotes cleavage
T-41 1189-1199 GENE denotes proinsulin
T-42 1203-1210 GENE denotes insulin
T-43 1242-1250 VAR denotes mutation
T-44 1260-1270 REG denotes identified
T-45 1278-1285 GENE denotes insulin
T-46 1318-1346 DISEASE denotes familial hyperproinsulinemia
T-47 1359-1367 VAR denotes mutation
T-48 1372-1380 REG denotes occurred
T-49 1616-1625 VAR denotes mutations
R-33 T-30 T-29 ThemeOf arginine,converting
R-34 T-30 T-31 ThemeOf arginine,CGT
R-35 T-30 T-33 ThemeOf arginine,CAT
R-36 T-31 T-28 ThemeOf CGT,mutation
R-37 T-33 T-31 ThemeOf CAT,CGT
R-38 T-32 T-28 ThemeOf histidine,mutation
R-39 T-32 T-29 ThemeOf histidine,converting
R-40 T-32 T-31 ThemeOf histidine,CGT
R-41 T-32 T-33 ThemeOf histidine,CAT
R-42 T-33 T-28 ThemeOf CAT,mutation
R-43 T-34 T-35 ThemeOf Arg65,proteolytic cleavage
R-44 T-36 T-35 ThemeOf insulin,proteolytic cleavage
R-45 T-36 T-37 ThemeOf insulin,mutation
R-46 T-37 T-38 CauseOf mutation,explains
R-49 T-41 T-40 ThemeOf proinsulin,cleavage
R-50 T-41 T-39 ThemeOf proinsulin,impairment
R-51 T-42 T-39 ThemeOf insulin,impairment
R-52 T-42 T-40 ThemeOf insulin,cleavage
R-53 T-45 T-43 ThemeOf insulin,mutation
R-54 T-45 T-44 ThemeOf insulin,identified
R-55 T-46 T-44 ThemeOf familial hyperproinsulinemia,identified
R-0 T-0 T-1 ThemeOf familial hyperproinsulinemia,due
R-1 T-2 T-0 CauseOf to,familial hyperproinsulinemia
R-2 T-3 T-0 CauseOf mutation,familial hyperproinsulinemia
R-3 T-3 T-1 CauseOf mutation,due
R-4 T-4 T-3 ThemeOf proinsulin,mutation
R-5 T-6 T-8 CauseOf Mutations,impair
R-6 T-7 T-6 ThemeOf insulin,Mutations
R-7 T-9 T-8 ThemeOf bioactivity,impair
R-8 T-10 T-9 ThemeOf insulin,bioactivity
R-9 T-10 T-8 ThemeOf insulin,impair
R-10 T-11 T-13 CauseOf mutations,impair
R-11 T-11 T-17 CauseOf mutations,alter
R-12 T-11 T-20 CauseOf mutations,reducing
R-13 T-13 T-20 CauseOf impair,reducing
R-14 T-14 T-13 ThemeOf posttranslational processing,impair
R-15 T-15 T-13 ThemeOf proinsulin,impair
R-16 T-15 T-14 ThemeOf proinsulin,posttranslational processing
R-17 T-16 T-13 ThemeOf insulin,impair
R-18 T-16 T-14 ThemeOf insulin,posttranslational processing
R-19 T-17 T-20 CauseOf alter,reducing
R-20 T-18 T-17 ThemeOf structure,alter
R-21 T-19 T-17 ThemeOf insulin,alter
R-22 T-19 T-18 ThemeOf insulin,structure
R-23 T-21 T-20 ThemeOf affinity,reducing
R-24 T-22 T-21 ThemeOf insulin receptor,affinity
R-25 T-23 T-24 CauseOf mutations,inhibit
R-26 T-25 T-24 ThemeOf conversion,inhibit
R-27 T-26 T-24 ThemeOf proinsulin,inhibit
R-28 T-26 T-25 ThemeOf proinsulin,conversion
R-29 T-27 T-24 ThemeOf insulin,inhibit
R-30 T-27 T-25 ThemeOf insulin,conversion
R-31 T-28 T-29 CauseOf mutation,converting
R-32 T-30 T-28 ThemeOf arginine,mutation
R-47 T-37 T-39 CauseOf mutation,impairment
R-48 T-40 T-39 ThemeOf cleavage,impairment