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PubMed:21937431 JSONTXT

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sentences

Id Subject Object Predicate Lexical cue
T1 0-72 Sentence denotes Silkworm apolipophorin protein inhibits Staphylococcus aureus virulence.
T2 73-147 Sentence denotes Silkworm hemolymph inhibits hemolysin production by Staphylococcus aureus.
T3 148-236 Sentence denotes We purified a factor in the silkworm hemolymph responsible for this inhibitory activity.
T4 237-327 Sentence denotes The final fraction with the greatest specific activity contained 220- and 74-kDa proteins.
T5 328-533 Sentence denotes Determination of the N-terminal amino acid sequence revealed that the 220- and 74-kDa proteins were apolipophorin I and apolipophorin II, respectively, indicating that the factor was apolipophorin (ApoLp).
T6 534-729 Sentence denotes The purified ApoLp fraction showed decreased expression of S. aureus hla encoding α-hemolysin, hlb encoding β-hemolysin, saeRS, and RNAIII, which activate the expression of these hemolysin genes.
T7 730-858 Sentence denotes Injection of an anti-ApoLp antibody into the hemolymph increased the sensitivity of silkworms to the lethal effect of S. aureus.
T8 859-960 Sentence denotes Hog gastric mucin, a mammalian homologue of ApoLp, decreased the expression of S. aureus hla and hlb.
T9 961-1159 Sentence denotes These findings suggest that ApoLp in the silkworm hemolymph inhibits S. aureus virulence and contributes to defense against S. aureus infection and that its activity is conserved in mammalian mucin.

Glycosmos6-MAT

Id Subject Object Predicate Lexical cue
T1 82-91 http://purl.obolibrary.org/obo/MAT_0000054 denotes hemolymph
T2 185-194 http://purl.obolibrary.org/obo/MAT_0000054 denotes hemolymph
T3 775-784 http://purl.obolibrary.org/obo/MAT_0000054 denotes hemolymph
T4 1011-1020 http://purl.obolibrary.org/obo/MAT_0000054 denotes hemolymph

silkworm

Id Subject Object Predicate Lexical cue
T1 0-8 Species:7091 denotes Silkworm
T2 40-61 Species:1280 denotes Staphylococcus aureus
T3 73-81 Species:7091 denotes Silkworm
T4 125-146 Species:1280 denotes Staphylococcus aureus
T5 176-184 Species:7091 denotes silkworm
T6 526-531 Gene:8542 denotes ApoLp
T7 547-552 Gene:8542 denotes ApoLp
T8 593-602 Species:1280 denotes S. aureus
T9 616-627 Gene:28381283 denotes α-hemolysin
T10 751-756 Gene:8542 denotes ApoLp
T11 814-823 Species:7091 denotes silkworms
T12 848-857 Species:1280 denotes S. aureus
T13 871-876 Gene:100508689 denotes mucin
T14 880-889 Species:9606 denotes mammalian
T15 903-908 Gene:8542 denotes ApoLp
T16 938-947 Species:1280 denotes S. aureus
T17 989-994 Gene:8542 denotes ApoLp
T18 1002-1010 Species:7091 denotes silkworm
T19 1030-1039 Species:1280 denotes S. aureus
T20 1088-1104 Disease:MESH:D013203 denotes aureus infection
T21 1143-1152 Species:9606 denotes mammalian
T22 1153-1158 Gene:100508689 denotes mucin

silkwormbase

Id Subject Object Predicate Lexical cue
T1 0-8 Species:7091 denotes Silkworm
T11 814-823 Species:7091 denotes silkworms
T12 848-857 Species:1280 denotes S. aureus
T13 871-876 Gene:100508689 denotes mucin
T14 880-889 Species:9606 denotes mammalian
T16 938-947 Species:1280 denotes S. aureus
T18 1002-1010 Species:7091 denotes silkworm
T19 1030-1039 Species:1280 denotes S. aureus
T2 40-61 Species:1280 denotes Staphylococcus aureus
T20 1088-1104 Disease:MESH:D013203 denotes aureus infection
T21 1143-1152 Species:9606 denotes mammalian
T22 1153-1158 Gene:100508689 denotes mucin
T3 73-81 Species:7091 denotes Silkworm
T4 125-146 Species:1280 denotes Staphylococcus aureus
T5 176-184 Species:7091 denotes silkworm
T8 593-602 Species:1280 denotes S. aureus
T9 616-627 Gene:28381283 denotes α-hemolysin

Allie

Id Subject Object Predicate Lexical cue
SS1_21937431_4_0 428-441 expanded denotes apolipophorin
SS2_21937431_4_0 526-531 abbr denotes ApoLp
AE1_21937431_4_0 SS1_21937431_4_0 SS2_21937431_4_0 abbreviatedTo apolipophorin,ApoLp

mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 1095-1104 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 82-91 Body_part denotes hemolymph http://purl.obolibrary.org/obo/MAT_0000054
T2 185-194 Body_part denotes hemolymph http://purl.obolibrary.org/obo/MAT_0000054
T3 775-784 Body_part denotes hemolymph http://purl.obolibrary.org/obo/MAT_0000054
T4 1011-1020 Body_part denotes hemolymph http://purl.obolibrary.org/obo/MAT_0000054

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 0-8 OrganismTaxon denotes Silkworm 7091
T2 40-61 OrganismTaxon denotes Staphylococcus aureus 1280
T3 73-81 OrganismTaxon denotes Silkworm 7091
T4 125-146 OrganismTaxon denotes Staphylococcus aureus 1280
T5 176-184 OrganismTaxon denotes silkworm 7091
T6 814-823 OrganismTaxon denotes silkworms 7091
T7 1002-1010 OrganismTaxon denotes silkworm 7091

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 82-91 Body_part denotes hemolymph http://purl.obolibrary.org/obo/UBERON_0001011
T2 185-194 Body_part denotes hemolymph http://purl.obolibrary.org/obo/UBERON_0001011
T3 775-784 Body_part denotes hemolymph http://purl.obolibrary.org/obo/UBERON_0001011
T4 1011-1020 Body_part denotes hemolymph http://purl.obolibrary.org/obo/UBERON_0001011