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GlyCosmos6-Glycan-Motif-Image

Id	Subject	Object	Predicate	Lexical cue	image
T1	84-108	Glycan_Motif	denotes	N-acetyl-neuraminic acid	https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81533KY\|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G50850NI
T3	311-322	Glycan_Motif	denotes	sialic acid	https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81533KY
T4	933-944	Glycan_Motif	denotes	sialic acid	https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81533KY
T5	1036-1060	Glycan_Motif	denotes	N-acetyl-neuraminic acid	https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81533KY\|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G50850NI
T7	1062-1067	Glycan_Motif	denotes	NeuAc	https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81533KY
T8	1283-1288	Glycan_Motif	denotes	NeuAc	https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81533KY
T9	1322-1327	Glycan_Motif	denotes	NeuAc	https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81533KY
T10	1452-1457	Glycan_Motif	denotes	NeuAc	https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81533KY
T11	1719-1724	Glycan_Motif	denotes	NeuAc	https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81533KY

sentences

Id	Subject	Object	Predicate	Lexical cue
T1	0-148	Sentence	denotes	Early murine T-lymphocyte activation is accompanied by a switch from N-Glycolyl- to N-acetyl-neuraminic acid and generation of ligands for siglec-E.
T2	149-369	Sentence	denotes	It is well established that murine T-lymphocyte activation is accompanied by major changes in cell-surface sialylation, potentially influencing interactions with sialic acid-binding immunoglobulin-like lectins (siglecs).
T3	370-467	Sentence	denotes	In the present study, we analyzed early activation of murine CD4+ and CD8+ T-lymphocytes at 24 h.
T4	468-693	Sentence	denotes	We observed a striking and selective up-regulation in the binding of a recombinant soluble form of siglec-E, an inhibitory siglec, which is expressed on several myeloid cell types including antigen-presenting dendritic cells.
T5	694-906	Sentence	denotes	In contrast, much lower levels of T cell binding were observed with other siglecs, including sialoadhesin, CD22, and siglec-F and the plant lectins Maackia amurensis leukoagglutinin and Sambucus nigra agglutinin.
T6	907-1120	Sentence	denotes	By mass spectrometry, the sialic acid content of 24-h-activated CD4+ and CD8+ T-lymphocytes exhibited an increased proportion of N-acetyl-neuraminic acid (NeuAc) to N-glycolyl-neuraminic acid (NeuGc) in N-glycans.
T7	1121-1359	Sentence	denotes	Reduced levels of NeuGc on the surface of activated T cells were demonstrated using an antibody specific for NeuGc and the expression levels of the gene encoding NeuAc- to NeuGc-converting enzyme, CMP-NeuAc hydroxylase, were also reduced.
T8	1360-1600	Sentence	denotes	Siglec-E bound a wide range of sialylated structures in glycan arrays, had a preference for NeuAc versus NeuGc-terminated sequences and could recognize a set of sialoglycoproteins that included CD45, in lysates from activated T-lymphocytes.
T9	1601-1784	Sentence	denotes	Collectively, these results show that early in T cell activation, glycan remodelling involves a switch from NeuGc- to NeuAc-terminating oligosaccharides on cell surface glycoproteins.
T10	1785-2003	Sentence	denotes	This is associated with a strong up-regulation of siglec-E ligands, which may be important in promoting cellular interactions between early activated T-lymphocytes and myeloid cells expressing this inhibitory receptor.

GlyCosmos6-Glycan-Motif-Structure

Id	Subject	Object	Predicate	Lexical cue
T1	84-108	https://glytoucan.org/Structures/Glycans/G50850NI	denotes	N-acetyl-neuraminic acid
T2	84-108	https://glytoucan.org/Structures/Glycans/G81533KY	denotes	N-acetyl-neuraminic acid
T3	311-322	https://glytoucan.org/Structures/Glycans/G81533KY	denotes	sialic acid
T4	933-944	https://glytoucan.org/Structures/Glycans/G81533KY	denotes	sialic acid
T5	1036-1060	https://glytoucan.org/Structures/Glycans/G50850NI	denotes	N-acetyl-neuraminic acid
T6	1036-1060	https://glytoucan.org/Structures/Glycans/G81533KY	denotes	N-acetyl-neuraminic acid

Glycan-GlyCosmos

Id	Subject	Object	Predicate	Lexical cue	image
T1	1062-1067	Glycan	denotes	NeuAc	https://api.glycosmos.org/wurcs2image/latest/png/binary/G76685HR
T2	1283-1288	Glycan	denotes	NeuAc	https://api.glycosmos.org/wurcs2image/latest/png/binary/G76685HR
T3	1322-1327	Glycan	denotes	NeuAc	https://api.glycosmos.org/wurcs2image/latest/png/binary/G76685HR
T4	1452-1457	Glycan	denotes	NeuAc	https://api.glycosmos.org/wurcs2image/latest/png/binary/G76685HR
T5	1719-1724	Glycan	denotes	NeuAc	https://api.glycosmos.org/wurcs2image/latest/png/binary/G76685HR

Allie

Id	Subject	Object	Predicate	Lexical cue
SS1_21835922_5_0	1036-1060	expanded	denotes	N-acetyl-neuraminic acid
SS2_21835922_5_0	1062-1067	abbr	denotes	NeuAc
SS1_21835922_5_1	1072-1098	expanded	denotes	N-glycolyl-neuraminic acid
SS2_21835922_5_1	1100-1105	abbr	denotes	NeuGc
AE1_21835922_5_0	SS1_21835922_5_0	SS2_21835922_5_0	abbreviatedTo	N-acetyl-neuraminic acid,NeuAc
AE1_21835922_5_1	SS1_21835922_5_1	SS2_21835922_5_1	abbreviatedTo	N-glycolyl-neuraminic acid,NeuGc

GlyCosmos15-NCBITAXON

Id	Subject	Object	Predicate	Lexical cue	db_id
T1	842-859	OrganismTaxon	denotes	Maackia amurensis	37501
T2	880-894	OrganismTaxon	denotes	Sambucus nigra	4202

GlyCosmos15-CL

Id	Subject	Object	Predicate	Lexical cue	cl_id
T1	13-25	Cell	denotes	T-lymphocyte	http://purl.obolibrary.org/obo/CL:0000084
T2	15-25	Cell	denotes	lymphocyte	http://purl.obolibrary.org/obo/CL:0000542
T3	184-196	Cell	denotes	T-lymphocyte	http://purl.obolibrary.org/obo/CL:0000084
T4	186-196	Cell	denotes	lymphocyte	http://purl.obolibrary.org/obo/CL:0000542
T5	445-458	Cell	denotes	T-lymphocytes	http://purl.obolibrary.org/obo/CL:0000084
T6	629-641	Cell	denotes	myeloid cell	http://purl.obolibrary.org/obo/CL:0000763
T7	677-692	Cell	denotes	dendritic cells	http://purl.obolibrary.org/obo/CL:0000451\|http://purl.obolibrary.org/obo/CL:0001056
T9	728-734	Cell	denotes	T cell	http://purl.obolibrary.org/obo/CL:0000084
T10	985-998	Cell	denotes	T-lymphocytes	http://purl.obolibrary.org/obo/CL:0000084
T11	1173-1180	Cell	denotes	T cells	http://purl.obolibrary.org/obo/CL:0000084
T12	1586-1599	Cell	denotes	T-lymphocytes	http://purl.obolibrary.org/obo/CL:0000084
T13	1648-1654	Cell	denotes	T cell	http://purl.obolibrary.org/obo/CL:0000084
T14	1935-1948	Cell	denotes	T-lymphocytes	http://purl.obolibrary.org/obo/CL:0000084
T15	1953-1966	Cell	denotes	myeloid cells	http://purl.obolibrary.org/obo/CL:0000763

GlyCosmos15-UBERON

Id	Subject	Object	Predicate	Lexical cue	uberon_id
T1	13-25	Body_part	denotes	T-lymphocyte	http://purl.obolibrary.org/obo/CL_0000084
T2	184-196	Body_part	denotes	T-lymphocyte	http://purl.obolibrary.org/obo/CL_0000084
T3	445-458	Body_part	denotes	T-lymphocytes	http://purl.obolibrary.org/obo/CL_0000084
T4	629-641	Body_part	denotes	myeloid cell	http://purl.obolibrary.org/obo/CL_0000763
T5	677-692	Body_part	denotes	dendritic cells	http://purl.obolibrary.org/obo/CL_0000451
T6	728-734	Body_part	denotes	T cell	http://purl.obolibrary.org/obo/CL_0000084
T7	985-998	Body_part	denotes	T-lymphocytes	http://purl.obolibrary.org/obo/CL_0000084
T8	1586-1599	Body_part	denotes	T-lymphocytes	http://purl.obolibrary.org/obo/CL_0000084
T9	1648-1654	Body_part	denotes	T cell	http://purl.obolibrary.org/obo/CL_0000084
T10	1935-1948	Body_part	denotes	T-lymphocytes	http://purl.obolibrary.org/obo/CL_0000084
T11	1953-1966	Body_part	denotes	myeloid cells	http://purl.obolibrary.org/obo/CL_0000763

sentences

Id	Subject	Object	Predicate	Lexical cue
T1	0-148	Sentence	denotes	Early murine T-lymphocyte activation is accompanied by a switch from N-Glycolyl- to N-acetyl-neuraminic acid and generation of ligands for siglec-E.
T2	149-369	Sentence	denotes	It is well established that murine T-lymphocyte activation is accompanied by major changes in cell-surface sialylation, potentially influencing interactions with sialic acid-binding immunoglobulin-like lectins (siglecs).
T3	370-467	Sentence	denotes	In the present study, we analyzed early activation of murine CD4+ and CD8+ T-lymphocytes at 24 h.
T4	468-693	Sentence	denotes	We observed a striking and selective up-regulation in the binding of a recombinant soluble form of siglec-E, an inhibitory siglec, which is expressed on several myeloid cell types including antigen-presenting dendritic cells.
T5	694-906	Sentence	denotes	In contrast, much lower levels of T cell binding were observed with other siglecs, including sialoadhesin, CD22, and siglec-F and the plant lectins Maackia amurensis leukoagglutinin and Sambucus nigra agglutinin.
T6	907-1120	Sentence	denotes	By mass spectrometry, the sialic acid content of 24-h-activated CD4+ and CD8+ T-lymphocytes exhibited an increased proportion of N-acetyl-neuraminic acid (NeuAc) to N-glycolyl-neuraminic acid (NeuGc) in N-glycans.
T7	1121-1359	Sentence	denotes	Reduced levels of NeuGc on the surface of activated T cells were demonstrated using an antibody specific for NeuGc and the expression levels of the gene encoding NeuAc- to NeuGc-converting enzyme, CMP-NeuAc hydroxylase, were also reduced.
T8	1360-1600	Sentence	denotes	Siglec-E bound a wide range of sialylated structures in glycan arrays, had a preference for NeuAc versus NeuGc-terminated sequences and could recognize a set of sialoglycoproteins that included CD45, in lysates from activated T-lymphocytes.
T9	1601-1784	Sentence	denotes	Collectively, these results show that early in T cell activation, glycan remodelling involves a switch from NeuGc- to NeuAc-terminating oligosaccharides on cell surface glycoproteins.
T10	1785-2003	Sentence	denotes	This is associated with a strong up-regulation of siglec-E ligands, which may be important in promoting cellular interactions between early activated T-lymphocytes and myeloid cells expressing this inhibitory receptor.

GlyCosmos15-Sentences

Id	Subject	Object	Predicate	Lexical cue
T1	0-148	Sentence	denotes	Early murine T-lymphocyte activation is accompanied by a switch from N-Glycolyl- to N-acetyl-neuraminic acid and generation of ligands for siglec-E.
T2	149-369	Sentence	denotes	It is well established that murine T-lymphocyte activation is accompanied by major changes in cell-surface sialylation, potentially influencing interactions with sialic acid-binding immunoglobulin-like lectins (siglecs).
T3	370-467	Sentence	denotes	In the present study, we analyzed early activation of murine CD4+ and CD8+ T-lymphocytes at 24 h.
T4	468-693	Sentence	denotes	We observed a striking and selective up-regulation in the binding of a recombinant soluble form of siglec-E, an inhibitory siglec, which is expressed on several myeloid cell types including antigen-presenting dendritic cells.
T5	694-906	Sentence	denotes	In contrast, much lower levels of T cell binding were observed with other siglecs, including sialoadhesin, CD22, and siglec-F and the plant lectins Maackia amurensis leukoagglutinin and Sambucus nigra agglutinin.
T6	907-1120	Sentence	denotes	By mass spectrometry, the sialic acid content of 24-h-activated CD4+ and CD8+ T-lymphocytes exhibited an increased proportion of N-acetyl-neuraminic acid (NeuAc) to N-glycolyl-neuraminic acid (NeuGc) in N-glycans.
T7	1121-1359	Sentence	denotes	Reduced levels of NeuGc on the surface of activated T cells were demonstrated using an antibody specific for NeuGc and the expression levels of the gene encoding NeuAc- to NeuGc-converting enzyme, CMP-NeuAc hydroxylase, were also reduced.
T8	1360-1600	Sentence	denotes	Siglec-E bound a wide range of sialylated structures in glycan arrays, had a preference for NeuAc versus NeuGc-terminated sequences and could recognize a set of sialoglycoproteins that included CD45, in lysates from activated T-lymphocytes.
T9	1601-1784	Sentence	denotes	Collectively, these results show that early in T cell activation, glycan remodelling involves a switch from NeuGc- to NeuAc-terminating oligosaccharides on cell surface glycoproteins.
T10	1785-2003	Sentence	denotes	This is associated with a strong up-regulation of siglec-E ligands, which may be important in promoting cellular interactions between early activated T-lymphocytes and myeloid cells expressing this inhibitory receptor.

GlyCosmos15-Glycan

Id	Subject	Object	Predicate	Lexical cue	image
T1	1062-1067	Glycan	denotes	NeuAc	https://api.glycosmos.org/wurcs2image/latest/png/binary/G76685HR
T2	1283-1288	Glycan	denotes	NeuAc	https://api.glycosmos.org/wurcs2image/latest/png/binary/G76685HR
T3	1322-1327	Glycan	denotes	NeuAc	https://api.glycosmos.org/wurcs2image/latest/png/binary/G76685HR
T4	1452-1457	Glycan	denotes	NeuAc	https://api.glycosmos.org/wurcs2image/latest/png/binary/G76685HR
T5	1719-1724	Glycan	denotes	NeuAc	https://api.glycosmos.org/wurcs2image/latest/png/binary/G76685HR

NCBITAXON

Id	Subject	Object	Predicate	Lexical cue	db_id
T1	842-859	OrganismTaxon	denotes	Maackia amurensis	37501
T2	880-894	OrganismTaxon	denotes	Sambucus nigra	4202

Anatomy-UBERON

Id	Subject	Object	Predicate	Lexical cue	uberon_id
T1	13-25	Body_part	denotes	T-lymphocyte	http://purl.obolibrary.org/obo/CL_0000084
T2	184-196	Body_part	denotes	T-lymphocyte	http://purl.obolibrary.org/obo/CL_0000084
T3	445-458	Body_part	denotes	T-lymphocytes	http://purl.obolibrary.org/obo/CL_0000084
T4	629-641	Body_part	denotes	myeloid cell	http://purl.obolibrary.org/obo/CL_0000763
T5	677-692	Body_part	denotes	dendritic cells	http://purl.obolibrary.org/obo/CL_0000451
T6	728-734	Body_part	denotes	T cell	http://purl.obolibrary.org/obo/CL_0000084
T7	985-998	Body_part	denotes	T-lymphocytes	http://purl.obolibrary.org/obo/CL_0000084
T8	1586-1599	Body_part	denotes	T-lymphocytes	http://purl.obolibrary.org/obo/CL_0000084
T9	1648-1654	Body_part	denotes	T cell	http://purl.obolibrary.org/obo/CL_0000084
T10	1935-1948	Body_part	denotes	T-lymphocytes	http://purl.obolibrary.org/obo/CL_0000084
T11	1953-1966	Body_part	denotes	myeloid cells	http://purl.obolibrary.org/obo/CL_0000763

CL-cell

Id	Subject	Object	Predicate	Lexical cue	cl_id
T1	13-25	Cell	denotes	T-lymphocyte	http://purl.obolibrary.org/obo/CL:0000084
T2	15-25	Cell	denotes	lymphocyte	http://purl.obolibrary.org/obo/CL:0000542
T3	184-196	Cell	denotes	T-lymphocyte	http://purl.obolibrary.org/obo/CL:0000084
T4	186-196	Cell	denotes	lymphocyte	http://purl.obolibrary.org/obo/CL:0000542
T5	445-458	Cell	denotes	T-lymphocytes	http://purl.obolibrary.org/obo/CL:0000084
T6	629-641	Cell	denotes	myeloid cell	http://purl.obolibrary.org/obo/CL:0000763
T7	677-692	Cell	denotes	dendritic cells	http://purl.obolibrary.org/obo/CL:0000451\|http://purl.obolibrary.org/obo/CL:0001056
T9	728-734	Cell	denotes	T cell	http://purl.obolibrary.org/obo/CL:0000084
T10	985-998	Cell	denotes	T-lymphocytes	http://purl.obolibrary.org/obo/CL:0000084
T11	1173-1180	Cell	denotes	T cells	http://purl.obolibrary.org/obo/CL:0000084
T12	1586-1599	Cell	denotes	T-lymphocytes	http://purl.obolibrary.org/obo/CL:0000084
T13	1648-1654	Cell	denotes	T cell	http://purl.obolibrary.org/obo/CL:0000084
T14	1935-1948	Cell	denotes	T-lymphocytes	http://purl.obolibrary.org/obo/CL:0000084
T15	1953-1966	Cell	denotes	myeloid cells	http://purl.obolibrary.org/obo/CL:0000763