Id |
Subject |
Object |
Predicate |
Lexical cue |
TextSentencer_T1 |
0-115 |
Sentence |
denotes |
A large heterozygous deletion including the entire C1 inhibitor gene in a sporadic case of hereditary angio-oedema. |
TextSentencer_T2 |
116-276 |
Sentence |
denotes |
C1 inhibitor (C1-INH) deficiency [hereditary or acquired angio-oedema (HAE or AAE)] is characterized by recurring episodes of subcutaneous or submucosal oedema. |
TextSentencer_T3 |
277-360 |
Sentence |
denotes |
Many different mutations in the C1-INH gene have been identified as a cause of HAE. |
TextSentencer_T4 |
361-450 |
Sentence |
denotes |
We investigated the molecular basis of the disease in a Japanese woman with sporadic HAE. |
TextSentencer_T5 |
451-530 |
Sentence |
denotes |
Direct sequencing of genomic DNA revealed no point mutation in the C1-INH gene. |
TextSentencer_T6 |
531-655 |
Sentence |
denotes |
Quantitative real-time PCR showed that the copy number of the C1-INH gene in the patient was half that of a healthy control. |
TextSentencer_T7 |
656-752 |
Sentence |
denotes |
Furthermore, we identified a 650-kbp deletion on the chromosome, which included the C1-INH gene. |
TextSentencer_T8 |
753-841 |
Sentence |
denotes |
We evaluated the correlation between the patient's attacks and her coagulation activity. |
TextSentencer_T9 |
842-1038 |
Sentence |
denotes |
The levels of D-dimer were high during the angio-oedema attacks, and often exceeded the normal range even during remission, thus the level of D-dimer reflected the activity of HAE in this patient. |
T1 |
0-115 |
Sentence |
denotes |
A large heterozygous deletion including the entire C1 inhibitor gene in a sporadic case of hereditary angio-oedema. |
T2 |
116-276 |
Sentence |
denotes |
C1 inhibitor (C1-INH) deficiency [hereditary or acquired angio-oedema (HAE or AAE)] is characterized by recurring episodes of subcutaneous or submucosal oedema. |
T3 |
277-360 |
Sentence |
denotes |
Many different mutations in the C1-INH gene have been identified as a cause of HAE. |
T4 |
361-450 |
Sentence |
denotes |
We investigated the molecular basis of the disease in a Japanese woman with sporadic HAE. |
T5 |
451-530 |
Sentence |
denotes |
Direct sequencing of genomic DNA revealed no point mutation in the C1-INH gene. |
T6 |
531-655 |
Sentence |
denotes |
Quantitative real-time PCR showed that the copy number of the C1-INH gene in the patient was half that of a healthy control. |
T7 |
656-752 |
Sentence |
denotes |
Furthermore, we identified a 650-kbp deletion on the chromosome, which included the C1-INH gene. |
T8 |
753-841 |
Sentence |
denotes |
We evaluated the correlation between the patient's attacks and her coagulation activity. |
T9 |
842-1038 |
Sentence |
denotes |
The levels of D-dimer were high during the angio-oedema attacks, and often exceeded the normal range even during remission, thus the level of D-dimer reflected the activity of HAE in this patient. |