PubMed:21751158
Annnotations
PubMed_ArguminSci
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 78-157 | DRI_Background | denotes | Thyroid hormone receptors (TR) are members of the nuclear receptor superfamily. |
| T2 | 158-206 | DRI_Approach | denotes | There are at least two TR isoforms, TRα and TRβ. |
| T3 | 207-306 | DRI_Background | denotes | The TRα isoform plays a critical role in mediating the action of thyroid hormone in adipose tissue. |
| T4 | 307-389 | DRI_Approach | denotes | We mapped the porcine TRα gene to chromosome 12 p11-p13, by using the ImpRH panel. |
| T5 | 390-529 | DRI_Outcome | denotes | We examined tissue-localization of TRα and determined expression patterns of TRα in porcine adipose tissue with quantitative real-time PCR. |
| T6 | 530-688 | DRI_Challenge | denotes | TRα was expressed in all tissues, including heart, liver, spleen, stomach, pancreas, brain, small intestine, skeletal muscle, and subcutaneous adipose tissue. |
| T7 | 689-756 | DRI_Background | denotes | In the adipose tissue, the expression of TRα decreased postnatally. |
| T8 | 757-882 | DRI_Outcome | denotes | Compared to Yorkshire pigs, Jinhua pigs had significantly lower expression levels of TRα gene in the subcutaneous fat tissue. |
| T9 | 883-996 | DRI_Outcome | denotes | The expression levels of β2-AR, HSL and ATGL were also significantly lower in Jinhua pigs than in Yorkshire pigs. |
| T10 | 997-1118 | DRI_Background | denotes | However, no significant differences in PPARγ and SREBP-1C expression levels were found between Jinhua and Yorkshire pigs. |
| T11 | 1119-1269 | DRI_Background | denotes | Incubation of porcine adipose tissue explants with high doses of isoproterenol (100 and 1000 nM) significantly increased the expression levels of TRα. |
| T12 | 1270-1395 | DRI_Outcome | denotes | We conclude that there is considerable evidence that TRα plays an important role in fat deposition in porcine adipose tissue. |
Goldhamster2_Cellosaurus
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 42-44 | CVCL_S572|Cancer_cell_line|Rattus norvegicus | denotes | TR |
| T2 | 105-107 | CVCL_S572|Cancer_cell_line|Rattus norvegicus | denotes | TR |
| T3 | 181-183 | CVCL_S572|Cancer_cell_line|Rattus norvegicus | denotes | TR |
| T4 | 194-196 | CVCL_S572|Cancer_cell_line|Rattus norvegicus | denotes | TR |
| T5 | 202-204 | CVCL_S572|Cancer_cell_line|Rattus norvegicus | denotes | TR |
| T6 | 211-213 | CVCL_S572|Cancer_cell_line|Rattus norvegicus | denotes | TR |
| T7 | 229-230 | CVCL_6479|Finite_cell_line|Mus musculus | denotes | a |
| T8 | 307-309 | CVCL_5M23|Cancer_cell_line|Mesocricetus auratus | denotes | We |
| T9 | 329-331 | CVCL_S572|Cancer_cell_line|Rattus norvegicus | denotes | TR |
| T10 | 355-358 | CVCL_S144|Cancer_cell_line|Mus musculus | denotes | p11 |
| T11 | 390-392 | CVCL_5M23|Cancer_cell_line|Mesocricetus auratus | denotes | We |
| T12 | 425-427 | CVCL_S572|Cancer_cell_line|Rattus norvegicus | denotes | TR |
| T13 | 467-469 | CVCL_S572|Cancer_cell_line|Rattus norvegicus | denotes | TR |
| T14 | 520-524 | CVCL_0047|Telomerase_immortalized_cell_line|Homo sapiens | denotes | time |
| T15 | 530-532 | CVCL_S572|Cancer_cell_line|Rattus norvegicus | denotes | TR |
| T16 | 730-732 | CVCL_S572|Cancer_cell_line|Rattus norvegicus | denotes | TR |
| T17 | 842-844 | CVCL_S572|Cancer_cell_line|Rattus norvegicus | denotes | TR |
| T18 | 1265-1267 | CVCL_S572|Cancer_cell_line|Rattus norvegicus | denotes | TR |
| T19 | 1270-1272 | CVCL_5M23|Cancer_cell_line|Mesocricetus auratus | denotes | We |
| T20 | 1323-1325 | CVCL_S572|Cancer_cell_line|Rattus norvegicus | denotes | TR |
| T21 | 1333-1335 | CVCL_8754|Cancer_cell_line|Homo sapiens | denotes | an |
| T22 | 1333-1335 | CVCL_H241|Cancer_cell_line|Homo sapiens | denotes | an |
GoldHamster
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 24-34 | GO:0065007 | denotes | regulation |
| T2 | 46-50 | SO:0000704 | denotes | gene |
| T4 | 62-76 | UBERON:0001013 | denotes | adipose tissue |
| T6 | 86-93 | D006728 | denotes | hormone |
| T7 | 86-93 | D006728 | denotes | hormone |
| T8 | 86-93 | CHEBI:24621 | denotes | hormone |
| T9 | 184-192 | D020033 | denotes | isoforms |
| T10 | 215-222 | SO:0001149 | denotes | isoform |
| T12 | 272-279 | 10572 | denotes | thyroid |
| T11 | 272-279 | UBERON:0002046 | denotes | thyroid |
| T14 | 272-287 | CHEBI:60311 | denotes | thyroid hormone |
| T19 | 291-305 | UBERON:0001013 | denotes | adipose tissue |
| T21 | 333-337 | SO:0000704 | denotes | gene |
| T22 | 341-351 | GO:0005694 | denotes | chromosome |
| T23 | 341-351 | SO:0000340 | denotes | chromosome |
| T24 | 355-358 | P05943 | denotes | p11 |
| T25 | 355-358 | Q9VLR5 | denotes | p11 |
| T26 | 355-358 | P27003 | denotes | p11 |
| T27 | 355-358 | PR:000014403 | denotes | p11 |
| T28 | 355-358 | P60902 | denotes | p11 |
| T29 | 355-358 | P08207 | denotes | p11 |
| T30 | 355-358 | Q924P2 | denotes | p11 |
| T31 | 355-358 | Q9T1T7 | denotes | p11 |
| T32 | 355-358 | Q5RKV6 | denotes | p11 |
| T33 | 355-358 | P27004 | denotes | p11 |
| T34 | 355-358 | P82657 | denotes | p11 |
| T37 | 355-358 | P60903 | denotes | p11 |
| T38 | 355-358 | PR:Q96519 | denotes | p11 |
| T40 | 355-358 | PR:000007263 | denotes | p11 |
| T41 | 355-358 | P04163 | denotes | p11 |
| T36 | 355-358 | CVCL_S144 | denotes | p11 |
| T35 | 355-358 | C013741 | denotes | p11 |
| T39 | 355-358 | C013741 | denotes | p11 |
| T42 | 359-362 | Q9T1T5 | denotes | p13 |
| T43 | 359-362 | PR:O49293 | denotes | p13 |
| T44 | 359-362 | PR:000026786 | denotes | p13 |
| T45 | 359-362 | O05290 | denotes | p13 |
| T46 | 359-362 | Q65675 | denotes | p13 |
| T47 | 359-362 | P08463 | denotes | p13 |
| T48 | 402-408 | UBERON:0000479 | denotes | tissue |
| T49 | 409-421 | GO:0051179 | denotes | localization |
| T51 | 482-496 | UBERON:0001013 | denotes | adipose tissue |
| T53 | 525-528 | Q41249 | denotes | PCR |
| T54 | 525-528 | O66148 | denotes | PCR |
| T55 | 525-528 | Q59987 | denotes | PCR |
| T56 | 525-528 | Q01289 | denotes | PCR |
| T57 | 525-528 | O80333 | denotes | PCR |
| T58 | 525-528 | P15904 | denotes | PCR |
| T59 | 525-528 | Q9SDT1 | denotes | PCR |
| T60 | 525-528 | Q39617 | denotes | PCR |
| T61 | 581-586 | UBERON:0002107 | denotes | liver |
| T62 | 588-594 | UBERON:0002106 | denotes | spleen |
| T63 | 596-603 | UBERON:0000945 | denotes | stomach |
| T64 | 605-613 | UBERON:3011040 | denotes | pancreas |
| T65 | 605-613 | UBERON:0001264 | denotes | pancreas |
| T66 | 615-620 | UBERON:6110636 | denotes | brain |
| T67 | 615-620 | UBERON:0000955 | denotes | brain |
| T68 | 622-637 | UBERON:0002108 | denotes | small intestine |
| T70 | 639-654 | UBERON:0014892 | denotes | skeletal muscle |
| T71 | 639-654 | UBERON:0001134 | denotes | skeletal muscle |
| T72 | 639-654 | UBERON:0014895 | denotes | skeletal muscle |
| T75 | 660-687 | UBERON:0002190 | denotes | subcutaneous adipose tissue |
| T80 | 696-710 | UBERON:0001013 | denotes | adipose tissue |
| T82 | 779-783 | PR:Q9W3Y4 | denotes | pigs |
| T85 | 779-783 | PR:Q6PD26 | denotes | pigs |
| T86 | 779-783 | PR:Q5XI31 | denotes | pigs |
| T87 | 779-783 | PR:Q96S52 | denotes | pigs |
| T88 | 779-783 | PR:000012706 | denotes | pigs |
| T83 | 779-783 | D013552 | denotes | pigs |
| T84 | 779-783 | 9823 | denotes | pigs |
| T89 | 792-796 | PR:Q9W3Y4 | denotes | pigs |
| T92 | 792-796 | PR:Q6PD26 | denotes | pigs |
| T93 | 792-796 | PR:Q5XI31 | denotes | pigs |
| T94 | 792-796 | PR:Q96S52 | denotes | pigs |
| T95 | 792-796 | PR:000012706 | denotes | pigs |
| T90 | 792-796 | D013552 | denotes | pigs |
| T91 | 792-796 | 9823 | denotes | pigs |
| T96 | 846-850 | SO:0000704 | denotes | gene |
| T97 | 858-874 | UBERON:0002190 | denotes | subcutaneous fat |
| T98 | 858-874 | UBERON:0013488 | denotes | subcutaneous fat |
| T100 | 871-874 | CHEBI:24021 | denotes | fat |
| T101 | 871-881 | UBERON:0001013 | denotes | fat tissue |
| T103 | 915-918 | P54310 | denotes | HSL |
| T105 | 915-918 | Q05469 | denotes | HSL |
| T106 | 915-918 | P0A3H6 | denotes | HSL |
| T108 | 915-918 | P0A3H5 | denotes | HSL |
| T109 | 915-918 | PR:000009834 | denotes | HSL |
| T111 | 915-918 | P15304 | denotes | HSL |
| T112 | 915-918 | Q9R101 | denotes | HSL |
| T113 | 915-918 | P16386 | denotes | HSL |
| T114 | 915-918 | Q68J42 | denotes | HSL |
| T104 | 915-918 | CHEBI:43164 | denotes | HSL |
| T107 | 915-918 | CHEBI:17289 | denotes | HSL |
| T110 | 915-918 | GO:0033878 | denotes | HSL |
| T115 | 923-927 | PR:000012942 | denotes | ATGL |
| T116 | 923-927 | PR:Q96AD5 | denotes | ATGL |
| T117 | 923-927 | PR:P0C548 | denotes | ATGL |
| T118 | 923-927 | PR:Q8BJ56 | denotes | ATGL |
| T119 | 968-972 | PR:Q9W3Y4 | denotes | pigs |
| T122 | 968-972 | PR:Q6PD26 | denotes | pigs |
| T123 | 968-972 | PR:Q5XI31 | denotes | pigs |
| T124 | 968-972 | PR:Q96S52 | denotes | pigs |
| T125 | 968-972 | PR:000012706 | denotes | pigs |
| T120 | 968-972 | D013552 | denotes | pigs |
| T121 | 968-972 | 9823 | denotes | pigs |
| T126 | 991-995 | PR:Q9W3Y4 | denotes | pigs |
| T129 | 991-995 | PR:Q6PD26 | denotes | pigs |
| T130 | 991-995 | PR:Q5XI31 | denotes | pigs |
| T131 | 991-995 | PR:Q96S52 | denotes | pigs |
| T132 | 991-995 | PR:000012706 | denotes | pigs |
| T127 | 991-995 | D013552 | denotes | pigs |
| T128 | 991-995 | 9823 | denotes | pigs |
| T134 | 1036-1040 | PR:000013056 | denotes | PPAR |
| T135 | 1036-1040 | PR:P37230 | denotes | PPAR |
| T136 | 1036-1040 | PR:Q07869 | denotes | PPAR |
| T137 | 1036-1040 | PR:P23204 | denotes | PPAR |
| T133 | 1036-1040 | D047492 | denotes | PPAR |
| T139 | 1046-1053 | O97676 | denotes | SREBP-1 |
| T140 | 1046-1053 | Q60416 | denotes | SREBP-1 |
| T141 | 1046-1053 | PR:P56720 | denotes | SREBP-1 |
| T142 | 1046-1053 | P36956 | denotes | SREBP-1 |
| T143 | 1046-1053 | P56720 | denotes | SREBP-1 |
| T144 | 1046-1053 | PR:P36956 | denotes | SREBP-1 |
| T145 | 1046-1053 | Q9WTN3 | denotes | SREBP-1 |
| T146 | 1046-1053 | PR:000015611 | denotes | SREBP-1 |
| T147 | 1046-1053 | PR:Q9WTN3 | denotes | SREBP-1 |
| T148 | 1046-1053 | PR:000028989 | denotes | SREBP-1 |
| T149 | 1046-1054 | D051780 | denotes | SREBP-1C |
| T150 | 1113-1117 | PR:Q9W3Y4 | denotes | pigs |
| T153 | 1113-1117 | PR:Q6PD26 | denotes | pigs |
| T154 | 1113-1117 | PR:Q5XI31 | denotes | pigs |
| T155 | 1113-1117 | PR:Q96S52 | denotes | pigs |
| T156 | 1113-1117 | PR:000012706 | denotes | pigs |
| T151 | 1113-1117 | D013552 | denotes | pigs |
| T152 | 1113-1117 | 9823 | denotes | pigs |
| T158 | 1141-1155 | UBERON:0001013 | denotes | adipose tissue |
| T160 | 1184-1197 | 6054 | denotes | isoproterenol |
| T161 | 1184-1197 | D007545 | denotes | isoproterenol |
| T162 | 1184-1197 | D007545 | denotes | isoproterenol |
| T163 | 1184-1197 | CHEBI:64317 | denotes | isoproterenol |
| T164 | 1184-1197 | CHEBI:6257 | denotes | isoproterenol |
| T165 | 1354-1357 | UBERON:0001013 | denotes | fat |
| T166 | 1354-1357 | CHEBI:24021 | denotes | fat |
| T168 | 1380-1394 | UBERON:0001013 | denotes | adipose tissue |
Allie
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| SS1_21751158_1_0 | 78-103 | expanded | denotes | Thyroid hormone receptors |
| SS2_21751158_1_0 | 105-107 | abbr | denotes | TR |
| AE1_21751158_1_0 | SS1_21751158_1_0 | SS2_21751158_1_0 | abbreviatedTo | Thyroid hormone receptors,TR |