PubMed:21751158
Annnotations
PubMed_ArguminSci
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 78-157 | DRI_Background | denotes | Thyroid hormone receptors (TR) are members of the nuclear receptor superfamily. |
T2 | 158-206 | DRI_Approach | denotes | There are at least two TR isoforms, TRα and TRβ. |
T3 | 207-306 | DRI_Background | denotes | The TRα isoform plays a critical role in mediating the action of thyroid hormone in adipose tissue. |
T4 | 307-389 | DRI_Approach | denotes | We mapped the porcine TRα gene to chromosome 12 p11-p13, by using the ImpRH panel. |
T5 | 390-529 | DRI_Outcome | denotes | We examined tissue-localization of TRα and determined expression patterns of TRα in porcine adipose tissue with quantitative real-time PCR. |
T6 | 530-688 | DRI_Challenge | denotes | TRα was expressed in all tissues, including heart, liver, spleen, stomach, pancreas, brain, small intestine, skeletal muscle, and subcutaneous adipose tissue. |
T7 | 689-756 | DRI_Background | denotes | In the adipose tissue, the expression of TRα decreased postnatally. |
T8 | 757-882 | DRI_Outcome | denotes | Compared to Yorkshire pigs, Jinhua pigs had significantly lower expression levels of TRα gene in the subcutaneous fat tissue. |
T9 | 883-996 | DRI_Outcome | denotes | The expression levels of β2-AR, HSL and ATGL were also significantly lower in Jinhua pigs than in Yorkshire pigs. |
T10 | 997-1118 | DRI_Background | denotes | However, no significant differences in PPARγ and SREBP-1C expression levels were found between Jinhua and Yorkshire pigs. |
T11 | 1119-1269 | DRI_Background | denotes | Incubation of porcine adipose tissue explants with high doses of isoproterenol (100 and 1000 nM) significantly increased the expression levels of TRα. |
T12 | 1270-1395 | DRI_Outcome | denotes | We conclude that there is considerable evidence that TRα plays an important role in fat deposition in porcine adipose tissue. |
Goldhamster2_Cellosaurus
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 42-44 | CVCL_S572|Cancer_cell_line|Rattus norvegicus | denotes | TR |
T2 | 105-107 | CVCL_S572|Cancer_cell_line|Rattus norvegicus | denotes | TR |
T3 | 181-183 | CVCL_S572|Cancer_cell_line|Rattus norvegicus | denotes | TR |
T4 | 194-196 | CVCL_S572|Cancer_cell_line|Rattus norvegicus | denotes | TR |
T5 | 202-204 | CVCL_S572|Cancer_cell_line|Rattus norvegicus | denotes | TR |
T6 | 211-213 | CVCL_S572|Cancer_cell_line|Rattus norvegicus | denotes | TR |
T7 | 229-230 | CVCL_6479|Finite_cell_line|Mus musculus | denotes | a |
T8 | 307-309 | CVCL_5M23|Cancer_cell_line|Mesocricetus auratus | denotes | We |
T9 | 329-331 | CVCL_S572|Cancer_cell_line|Rattus norvegicus | denotes | TR |
T10 | 355-358 | CVCL_S144|Cancer_cell_line|Mus musculus | denotes | p11 |
T11 | 390-392 | CVCL_5M23|Cancer_cell_line|Mesocricetus auratus | denotes | We |
T12 | 425-427 | CVCL_S572|Cancer_cell_line|Rattus norvegicus | denotes | TR |
T13 | 467-469 | CVCL_S572|Cancer_cell_line|Rattus norvegicus | denotes | TR |
T14 | 520-524 | CVCL_0047|Telomerase_immortalized_cell_line|Homo sapiens | denotes | time |
T15 | 530-532 | CVCL_S572|Cancer_cell_line|Rattus norvegicus | denotes | TR |
T16 | 730-732 | CVCL_S572|Cancer_cell_line|Rattus norvegicus | denotes | TR |
T17 | 842-844 | CVCL_S572|Cancer_cell_line|Rattus norvegicus | denotes | TR |
T18 | 1265-1267 | CVCL_S572|Cancer_cell_line|Rattus norvegicus | denotes | TR |
T19 | 1270-1272 | CVCL_5M23|Cancer_cell_line|Mesocricetus auratus | denotes | We |
T20 | 1323-1325 | CVCL_S572|Cancer_cell_line|Rattus norvegicus | denotes | TR |
T21 | 1333-1335 | CVCL_8754|Cancer_cell_line|Homo sapiens | denotes | an |
T22 | 1333-1335 | CVCL_H241|Cancer_cell_line|Homo sapiens | denotes | an |
GoldHamster
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 24-34 | GO:0065007 | denotes | regulation |
T2 | 46-50 | SO:0000704 | denotes | gene |
T4 | 62-76 | UBERON:0001013 | denotes | adipose tissue |
T6 | 86-93 | D006728 | denotes | hormone |
T7 | 86-93 | D006728 | denotes | hormone |
T8 | 86-93 | CHEBI:24621 | denotes | hormone |
T9 | 184-192 | D020033 | denotes | isoforms |
T10 | 215-222 | SO:0001149 | denotes | isoform |
T12 | 272-279 | 10572 | denotes | thyroid |
T11 | 272-279 | UBERON:0002046 | denotes | thyroid |
T14 | 272-287 | CHEBI:60311 | denotes | thyroid hormone |
T19 | 291-305 | UBERON:0001013 | denotes | adipose tissue |
T21 | 333-337 | SO:0000704 | denotes | gene |
T22 | 341-351 | GO:0005694 | denotes | chromosome |
T23 | 341-351 | SO:0000340 | denotes | chromosome |
T24 | 355-358 | P05943 | denotes | p11 |
T25 | 355-358 | Q9VLR5 | denotes | p11 |
T26 | 355-358 | P27003 | denotes | p11 |
T27 | 355-358 | PR:000014403 | denotes | p11 |
T28 | 355-358 | P60902 | denotes | p11 |
T29 | 355-358 | P08207 | denotes | p11 |
T30 | 355-358 | Q924P2 | denotes | p11 |
T31 | 355-358 | Q9T1T7 | denotes | p11 |
T32 | 355-358 | Q5RKV6 | denotes | p11 |
T33 | 355-358 | P27004 | denotes | p11 |
T34 | 355-358 | P82657 | denotes | p11 |
T37 | 355-358 | P60903 | denotes | p11 |
T38 | 355-358 | PR:Q96519 | denotes | p11 |
T40 | 355-358 | PR:000007263 | denotes | p11 |
T41 | 355-358 | P04163 | denotes | p11 |
T36 | 355-358 | CVCL_S144 | denotes | p11 |
T35 | 355-358 | C013741 | denotes | p11 |
T39 | 355-358 | C013741 | denotes | p11 |
T42 | 359-362 | Q9T1T5 | denotes | p13 |
T43 | 359-362 | PR:O49293 | denotes | p13 |
T44 | 359-362 | PR:000026786 | denotes | p13 |
T45 | 359-362 | O05290 | denotes | p13 |
T46 | 359-362 | Q65675 | denotes | p13 |
T47 | 359-362 | P08463 | denotes | p13 |
T48 | 402-408 | UBERON:0000479 | denotes | tissue |
T49 | 409-421 | GO:0051179 | denotes | localization |
T51 | 482-496 | UBERON:0001013 | denotes | adipose tissue |
T53 | 525-528 | Q41249 | denotes | PCR |
T54 | 525-528 | O66148 | denotes | PCR |
T55 | 525-528 | Q59987 | denotes | PCR |
T56 | 525-528 | Q01289 | denotes | PCR |
T57 | 525-528 | O80333 | denotes | PCR |
T58 | 525-528 | P15904 | denotes | PCR |
T59 | 525-528 | Q9SDT1 | denotes | PCR |
T60 | 525-528 | Q39617 | denotes | PCR |
T61 | 581-586 | UBERON:0002107 | denotes | liver |
T62 | 588-594 | UBERON:0002106 | denotes | spleen |
T63 | 596-603 | UBERON:0000945 | denotes | stomach |
T64 | 605-613 | UBERON:3011040 | denotes | pancreas |
T65 | 605-613 | UBERON:0001264 | denotes | pancreas |
T66 | 615-620 | UBERON:6110636 | denotes | brain |
T67 | 615-620 | UBERON:0000955 | denotes | brain |
T68 | 622-637 | UBERON:0002108 | denotes | small intestine |
T70 | 639-654 | UBERON:0014892 | denotes | skeletal muscle |
T71 | 639-654 | UBERON:0001134 | denotes | skeletal muscle |
T72 | 639-654 | UBERON:0014895 | denotes | skeletal muscle |
T75 | 660-687 | UBERON:0002190 | denotes | subcutaneous adipose tissue |
T80 | 696-710 | UBERON:0001013 | denotes | adipose tissue |
T82 | 779-783 | PR:Q9W3Y4 | denotes | pigs |
T85 | 779-783 | PR:Q6PD26 | denotes | pigs |
T86 | 779-783 | PR:Q5XI31 | denotes | pigs |
T87 | 779-783 | PR:Q96S52 | denotes | pigs |
T88 | 779-783 | PR:000012706 | denotes | pigs |
T83 | 779-783 | D013552 | denotes | pigs |
T84 | 779-783 | 9823 | denotes | pigs |
T89 | 792-796 | PR:Q9W3Y4 | denotes | pigs |
T92 | 792-796 | PR:Q6PD26 | denotes | pigs |
T93 | 792-796 | PR:Q5XI31 | denotes | pigs |
T94 | 792-796 | PR:Q96S52 | denotes | pigs |
T95 | 792-796 | PR:000012706 | denotes | pigs |
T90 | 792-796 | D013552 | denotes | pigs |
T91 | 792-796 | 9823 | denotes | pigs |
T96 | 846-850 | SO:0000704 | denotes | gene |
T97 | 858-874 | UBERON:0002190 | denotes | subcutaneous fat |
T98 | 858-874 | UBERON:0013488 | denotes | subcutaneous fat |
T100 | 871-874 | CHEBI:24021 | denotes | fat |
T101 | 871-881 | UBERON:0001013 | denotes | fat tissue |
T103 | 915-918 | P54310 | denotes | HSL |
T105 | 915-918 | Q05469 | denotes | HSL |
T106 | 915-918 | P0A3H6 | denotes | HSL |
T108 | 915-918 | P0A3H5 | denotes | HSL |
T109 | 915-918 | PR:000009834 | denotes | HSL |
T111 | 915-918 | P15304 | denotes | HSL |
T112 | 915-918 | Q9R101 | denotes | HSL |
T113 | 915-918 | P16386 | denotes | HSL |
T114 | 915-918 | Q68J42 | denotes | HSL |
T104 | 915-918 | CHEBI:43164 | denotes | HSL |
T107 | 915-918 | CHEBI:17289 | denotes | HSL |
T110 | 915-918 | GO:0033878 | denotes | HSL |
T115 | 923-927 | PR:000012942 | denotes | ATGL |
T116 | 923-927 | PR:Q96AD5 | denotes | ATGL |
T117 | 923-927 | PR:P0C548 | denotes | ATGL |
T118 | 923-927 | PR:Q8BJ56 | denotes | ATGL |
T119 | 968-972 | PR:Q9W3Y4 | denotes | pigs |
T122 | 968-972 | PR:Q6PD26 | denotes | pigs |
T123 | 968-972 | PR:Q5XI31 | denotes | pigs |
T124 | 968-972 | PR:Q96S52 | denotes | pigs |
T125 | 968-972 | PR:000012706 | denotes | pigs |
T120 | 968-972 | D013552 | denotes | pigs |
T121 | 968-972 | 9823 | denotes | pigs |
T126 | 991-995 | PR:Q9W3Y4 | denotes | pigs |
T129 | 991-995 | PR:Q6PD26 | denotes | pigs |
T130 | 991-995 | PR:Q5XI31 | denotes | pigs |
T131 | 991-995 | PR:Q96S52 | denotes | pigs |
T132 | 991-995 | PR:000012706 | denotes | pigs |
T127 | 991-995 | D013552 | denotes | pigs |
T128 | 991-995 | 9823 | denotes | pigs |
T134 | 1036-1040 | PR:000013056 | denotes | PPAR |
T135 | 1036-1040 | PR:P37230 | denotes | PPAR |
T136 | 1036-1040 | PR:Q07869 | denotes | PPAR |
T137 | 1036-1040 | PR:P23204 | denotes | PPAR |
T133 | 1036-1040 | D047492 | denotes | PPAR |
T139 | 1046-1053 | O97676 | denotes | SREBP-1 |
T140 | 1046-1053 | Q60416 | denotes | SREBP-1 |
T141 | 1046-1053 | PR:P56720 | denotes | SREBP-1 |
T142 | 1046-1053 | P36956 | denotes | SREBP-1 |
T143 | 1046-1053 | P56720 | denotes | SREBP-1 |
T144 | 1046-1053 | PR:P36956 | denotes | SREBP-1 |
T145 | 1046-1053 | Q9WTN3 | denotes | SREBP-1 |
T146 | 1046-1053 | PR:000015611 | denotes | SREBP-1 |
T147 | 1046-1053 | PR:Q9WTN3 | denotes | SREBP-1 |
T148 | 1046-1053 | PR:000028989 | denotes | SREBP-1 |
T149 | 1046-1054 | D051780 | denotes | SREBP-1C |
T150 | 1113-1117 | PR:Q9W3Y4 | denotes | pigs |
T153 | 1113-1117 | PR:Q6PD26 | denotes | pigs |
T154 | 1113-1117 | PR:Q5XI31 | denotes | pigs |
T155 | 1113-1117 | PR:Q96S52 | denotes | pigs |
T156 | 1113-1117 | PR:000012706 | denotes | pigs |
T151 | 1113-1117 | D013552 | denotes | pigs |
T152 | 1113-1117 | 9823 | denotes | pigs |
T158 | 1141-1155 | UBERON:0001013 | denotes | adipose tissue |
T160 | 1184-1197 | 6054 | denotes | isoproterenol |
T161 | 1184-1197 | D007545 | denotes | isoproterenol |
T162 | 1184-1197 | D007545 | denotes | isoproterenol |
T163 | 1184-1197 | CHEBI:64317 | denotes | isoproterenol |
T164 | 1184-1197 | CHEBI:6257 | denotes | isoproterenol |
T165 | 1354-1357 | UBERON:0001013 | denotes | fat |
T166 | 1354-1357 | CHEBI:24021 | denotes | fat |
T168 | 1380-1394 | UBERON:0001013 | denotes | adipose tissue |
Allie
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
SS1_21751158_1_0 | 78-103 | expanded | denotes | Thyroid hormone receptors |
SS2_21751158_1_0 | 105-107 | abbr | denotes | TR |
AE1_21751158_1_0 | SS1_21751158_1_0 | SS2_21751158_1_0 | abbreviatedTo | Thyroid hormone receptors,TR |