PubMed:21750150
Annnotations
LitCoin-entities-OrganismTaxon-PD
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 710-714 | OrganismTaxon | denotes | mice | NCBItxid:10095|NCBItxid:10088 |
LitCoin-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-84 | Sentence | denotes | Homozygously deleted gene DACH1 regulates tumor-initiating activity of glioma cells. |
| T2 | 85-170 | Sentence | denotes | Loss or reduction in function of tumor suppressor genes contributes to tumorigenesis. |
| T3 | 171-397 | Sentence | denotes | Here, by allelic DNA copy number analysis using single-nucleotide polymorphism genotyping array and mass spectrometry, we report homozygous deletion in glioblastoma multiformes at chromosome 13q21, where DACH1 gene is located. |
| T4 | 398-499 | Sentence | denotes | We found decreased cell proliferation of a series of glioma cell lines by forced expression of DACH1. |
| T5 | 500-623 | Sentence | denotes | We then generated U87TR-Da glioma cells, where DACH1 expression could be activated by exposure of the cells to doxycycline. |
| T6 | 624-850 | Sentence | denotes | Both ex vivo cellular proliferation and in vivo growth of s.c. transplanted tumors in mice are reduced in U87TR-Da cells with DACH1 expression (U87-DACH1-high), compared with DACH1-nonexpressing U87TR-Da cells (U87-DACH1-low). |
| T7 | 851-972 | Sentence | denotes | U87-DACH1-low cells form spheroids with CD133 and Nestin expression in serum-free medium but U87-DACH1-high cells do not. |
| T8 | 973-1149 | Sentence | denotes | Compared with spheroid-forming U87-DACH1-low cells, adherent U87-DACH1-high cells display lower tumorigenicity, indicating DACH1 decreases the number of tumor-initiating cells. |
| T9 | 1150-1357 | Sentence | denotes | Gene expression analysis and chromatin immunoprecipitation assay reveal that fibroblast growth factor 2 (FGF2/bFGF) is transcriptionally repressed by DACH1, especially in cells cultured in serum-free medium. |
| T10 | 1358-1575 | Sentence | denotes | Exogenous bFGF rescues spheroid-forming activity and tumorigenicity of the U87-DACH1-high cells, suggesting that loss of DACH1 increases the number of tumor-initiating cells through transcriptional activation of bFGF. |
| T11 | 1576-1773 | Sentence | denotes | These results illustrate that DACH1 is a distinctive tumor suppressor, which does not only suppress growth of tumor cells but also regulates bFGF-mediated tumor-initiating activity of glioma cells. |
LitCoin-entities
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| 8773 | 772-777 | GeneOrGeneProduct | denotes | DACH1 | NCBIGene:1602 |
| 8755 | 26-31 | GeneOrGeneProduct | denotes | DACH1 | NCBIGene:1602 |
| 8756 | 42-47 | DiseaseOrPhenotypicFeature | denotes | tumor | MESH:D009369 |
| 8757 | 71-77 | DiseaseOrPhenotypicFeature | denotes | glioma | MESH:D005910 |
| 8758 | 118-123 | DiseaseOrPhenotypicFeature | denotes | tumor | MESH:D009369 |
| 8759 | 156-169 | DiseaseOrPhenotypicFeature | denotes | tumorigenesis | MESH:D009369 |
| 8760 | 323-335 | DiseaseOrPhenotypicFeature | denotes | glioblastoma | MESH:D005909 |
| 8761 | 375-380 | GeneOrGeneProduct | denotes | DACH1 | NCBIGene:1602 |
| 8762 | 451-457 | DiseaseOrPhenotypicFeature | denotes | glioma | MESH:D005910 |
| 8763 | 493-498 | GeneOrGeneProduct | denotes | DACH1 | NCBIGene:1602 |
| 8764 | 518-526 | CellLine | denotes | U87TR-Da | NCBITaxon:9606 |
| 8765 | 527-533 | DiseaseOrPhenotypicFeature | denotes | glioma | MESH:D005910 |
| 8766 | 547-552 | GeneOrGeneProduct | denotes | DACH1 | NCBIGene:1602 |
| 8767 | 611-622 | ChemicalEntity | denotes | doxycycline | MESH:D004318 |
| 8768 | 700-706 | DiseaseOrPhenotypicFeature | denotes | tumors | MESH:D009369 |
| 8769 | 710-714 | OrganismTaxon | denotes | mice | NCBITaxon:10090 |
| 8770 | 730-738 | CellLine | denotes | U87TR-Da | NCBITaxon:9606 |
| 8771 | 750-755 | GeneOrGeneProduct | denotes | DACH1 | NCBIGene:1602 |
| 8772 | 768-771 | CellLine | denotes | U87 | NCBITaxon:9606 |
| 8774 | 799-804 | GeneOrGeneProduct | denotes | DACH1 | NCBIGene:1602 |
| 8775 | 819-827 | CellLine | denotes | U87TR-Da | NCBITaxon:9606 |
| 8776 | 835-838 | CellLine | denotes | U87 | NCBITaxon:9606 |
| 8777 | 839-844 | GeneOrGeneProduct | denotes | DACH1 | NCBIGene:1602 |
| 8778 | 851-854 | CellLine | denotes | U87 | NCBITaxon:9606 |
| 8779 | 855-860 | GeneOrGeneProduct | denotes | DACH1 | NCBIGene:1602 |
| 8780 | 891-896 | GeneOrGeneProduct | denotes | CD133 | NCBIGene:8842 |
| 8781 | 901-907 | GeneOrGeneProduct | denotes | Nestin | NCBIGene:10763 |
| 8782 | 944-947 | CellLine | denotes | U87 | NCBITaxon:9606 |
| 8783 | 948-953 | GeneOrGeneProduct | denotes | DACH1 | NCBIGene:1602 |
| 8784 | 1004-1007 | CellLine | denotes | U87 | NCBITaxon:9606 |
| 8785 | 1008-1013 | GeneOrGeneProduct | denotes | DACH1 | NCBIGene:1602 |
| 8786 | 1034-1037 | CellLine | denotes | U87 | NCBITaxon:9606 |
| 8787 | 1038-1043 | GeneOrGeneProduct | denotes | DACH1 | NCBIGene:1602 |
| 8788 | 1096-1101 | GeneOrGeneProduct | denotes | DACH1 | NCBIGene:1602 |
| 8789 | 1126-1131 | DiseaseOrPhenotypicFeature | denotes | tumor | MESH:D009369 |
| 8790 | 1227-1253 | GeneOrGeneProduct | denotes | fibroblast growth factor 2 | NCBIGene:2247 |
| 8791 | 1255-1259 | GeneOrGeneProduct | denotes | FGF2 | NCBIGene:2247 |
| 8792 | 1260-1264 | GeneOrGeneProduct | denotes | bFGF | NCBIGene:2247 |
| 8793 | 1300-1305 | GeneOrGeneProduct | denotes | DACH1 | NCBIGene:1602 |
| 8794 | 1368-1372 | GeneOrGeneProduct | denotes | bFGF | NCBIGene:2247 |
| 8795 | 1433-1436 | CellLine | denotes | U87 | NCBITaxon:9606 |
| 8796 | 1437-1442 | GeneOrGeneProduct | denotes | DACH1 | NCBIGene:1602 |
| 8797 | 1479-1484 | GeneOrGeneProduct | denotes | DACH1 | NCBIGene:1602 |
| 8798 | 1509-1514 | DiseaseOrPhenotypicFeature | denotes | tumor | MESH:D009369 |
| 8799 | 1570-1574 | GeneOrGeneProduct | denotes | bFGF | NCBIGene:2247 |
| 8800 | 1606-1611 | GeneOrGeneProduct | denotes | DACH1 | NCBIGene:1602 |
| 8801 | 1629-1634 | DiseaseOrPhenotypicFeature | denotes | tumor | MESH:D009369 |
| 8802 | 1686-1691 | DiseaseOrPhenotypicFeature | denotes | tumor | MESH:D009369 |
| 8803 | 1717-1721 | GeneOrGeneProduct | denotes | bFGF | NCBIGene:2247 |
| 8804 | 1731-1736 | DiseaseOrPhenotypicFeature | denotes | tumor | MESH:D009369 |
| 8805 | 1760-1766 | DiseaseOrPhenotypicFeature | denotes | glioma | MESH:D005910 |
LitCoin_Mondo
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 71-77 | DiseaseOrPhenotypicFeature | denotes | glioma | 0021042 |
| T2 | 323-335 | DiseaseOrPhenotypicFeature | denotes | glioblastoma | 0018177 |
| T3 | 451-457 | DiseaseOrPhenotypicFeature | denotes | glioma | 0021042 |
| T4 | 527-533 | DiseaseOrPhenotypicFeature | denotes | glioma | 0021042 |
| T5 | 1760-1766 | DiseaseOrPhenotypicFeature | denotes | glioma | 0021042 |
LitCoin-GeneOrGeneProduct-v0
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T56 | 1381-1389 | GeneOrGeneProduct | denotes | spheroid |
| T57 | 1398-1406 | GeneOrGeneProduct | denotes | activity |
| T58 | 1437-1442 | GeneOrGeneProduct | denotes | DACH1 |
| T59 | 1443-1447 | GeneOrGeneProduct | denotes | high |
| T60 | 1448-1453 | GeneOrGeneProduct | denotes | cells |
| T61 | 1479-1484 | GeneOrGeneProduct | denotes | DACH1 |
| T62 | 1506-1514 | GeneOrGeneProduct | denotes | of tumor |
| T63 | 1515-1525 | GeneOrGeneProduct | denotes | initiating |
| T64 | 1526-1531 | GeneOrGeneProduct | denotes | cells |
| T65 | 1540-1555 | GeneOrGeneProduct | denotes | transcriptional |
| T66 | 1556-1566 | GeneOrGeneProduct | denotes | activation |
| T1 | 26-31 | GeneOrGeneProduct | denotes | DACH1 |
| T2 | 32-41 | GeneOrGeneProduct | denotes | regulates |
| T3 | 42-47 | GeneOrGeneProduct | denotes | tumor |
| T4 | 48-58 | GeneOrGeneProduct | denotes | initiating |
| T5 | 59-67 | GeneOrGeneProduct | denotes | activity |
| T6 | 78-83 | GeneOrGeneProduct | denotes | cells |
| T7 | 118-134 | GeneOrGeneProduct | denotes | tumor suppressor |
| T8 | 271-275 | GeneOrGeneProduct | denotes | mass |
| T9 | 375-380 | GeneOrGeneProduct | denotes | DACH1 |
| T10 | 417-421 | GeneOrGeneProduct | denotes | cell |
| T11 | 422-440 | GeneOrGeneProduct | denotes | proliferation of a |
| T12 | 458-462 | GeneOrGeneProduct | denotes | cell |
| T54 | 1321-1326 | GeneOrGeneProduct | denotes | cells |
| T13 | 463-468 | GeneOrGeneProduct | denotes | lines |
| T55 | 1368-1372 | GeneOrGeneProduct | denotes | bFGF |
| T14 | 472-478 | GeneOrGeneProduct | denotes | forced |
| T15 | 493-498 | GeneOrGeneProduct | denotes | DACH1 |
| T16 | 534-539 | GeneOrGeneProduct | denotes | cells |
| T17 | 547-552 | GeneOrGeneProduct | denotes | DACH1 |
| T18 | 573-582 | GeneOrGeneProduct | denotes | activated |
| T19 | 602-607 | GeneOrGeneProduct | denotes | cells |
| T20 | 672-678 | GeneOrGeneProduct | denotes | growth |
| T21 | 700-706 | GeneOrGeneProduct | denotes | tumors |
| T22 | 710-714 | GeneOrGeneProduct | denotes | mice |
| T23 | 719-726 | GeneOrGeneProduct | denotes | reduced |
| T24 | 739-744 | GeneOrGeneProduct | denotes | cells |
| T25 | 750-755 | GeneOrGeneProduct | denotes | DACH1 |
| T26 | 772-777 | GeneOrGeneProduct | denotes | DACH1 |
| T27 | 778-782 | GeneOrGeneProduct | denotes | high |
| T28 | 799-804 | GeneOrGeneProduct | denotes | DACH1 |
| T29 | 828-833 | GeneOrGeneProduct | denotes | cells |
| T30 | 839-844 | GeneOrGeneProduct | denotes | DACH1 |
| T31 | 855-860 | GeneOrGeneProduct | denotes | DACH1 |
| T32 | 865-870 | GeneOrGeneProduct | denotes | cells |
| T33 | 876-885 | GeneOrGeneProduct | denotes | spheroids |
| T34 | 891-896 | GeneOrGeneProduct | denotes | CD133 |
| T35 | 901-907 | GeneOrGeneProduct | denotes | Nestin |
| T36 | 948-953 | GeneOrGeneProduct | denotes | DACH1 |
| T37 | 954-958 | GeneOrGeneProduct | denotes | high |
| T38 | 959-964 | GeneOrGeneProduct | denotes | cells |
| T39 | 987-995 | GeneOrGeneProduct | denotes | spheroid |
| T40 | 1008-1013 | GeneOrGeneProduct | denotes | DACH1 |
| T41 | 1018-1023 | GeneOrGeneProduct | denotes | cells |
| T42 | 1038-1043 | GeneOrGeneProduct | denotes | DACH1 |
| T43 | 1044-1048 | GeneOrGeneProduct | denotes | high |
| T44 | 1049-1054 | GeneOrGeneProduct | denotes | cells |
| T45 | 1096-1101 | GeneOrGeneProduct | denotes | DACH1 |
| T46 | 1123-1131 | GeneOrGeneProduct | denotes | of tumor |
| T47 | 1132-1142 | GeneOrGeneProduct | denotes | initiating |
| T48 | 1143-1148 | GeneOrGeneProduct | denotes | cells |
| T49 | 1227-1253 | GeneOrGeneProduct | denotes | fibroblast growth factor 2 |
| T50 | 1255-1259 | GeneOrGeneProduct | denotes | FGF2 |
| T51 | 1260-1264 | GeneOrGeneProduct | denotes | bFGF |
| T52 | 1269-1286 | GeneOrGeneProduct | denotes | transcriptionally |
| T53 | 1300-1305 | GeneOrGeneProduct | denotes | DACH1 |
| T67 | 1570-1574 | GeneOrGeneProduct | denotes | bFGF |
| T68 | 1606-1611 | GeneOrGeneProduct | denotes | DACH1 |
| T69 | 1629-1645 | GeneOrGeneProduct | denotes | tumor suppressor |
| T70 | 1676-1682 | GeneOrGeneProduct | denotes | growth |
| T71 | 1683-1691 | GeneOrGeneProduct | denotes | of tumor |
| T72 | 1692-1697 | GeneOrGeneProduct | denotes | cells |
| T73 | 1707-1716 | GeneOrGeneProduct | denotes | regulates |
| T74 | 1717-1721 | GeneOrGeneProduct | denotes | bFGF |
| T75 | 1722-1730 | GeneOrGeneProduct | denotes | mediated |
| T76 | 1731-1736 | GeneOrGeneProduct | denotes | tumor |
| T77 | 1737-1747 | GeneOrGeneProduct | denotes | initiating |
| T78 | 1748-1756 | GeneOrGeneProduct | denotes | activity |
| T79 | 1767-1772 | GeneOrGeneProduct | denotes | cells |
LitCoin-GeneOrGeneProduct-v2
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 26-31 | GeneOrGeneProduct | denotes | DACH1 |
| T2 | 118-134 | GeneOrGeneProduct | denotes | tumor suppressor |
| T3 | 375-380 | GeneOrGeneProduct | denotes | DACH1 |
| T4 | 417-421 | GeneOrGeneProduct | denotes | cell |
| T5 | 458-462 | GeneOrGeneProduct | denotes | cell |
| T6 | 463-468 | GeneOrGeneProduct | denotes | lines |
| T7 | 493-498 | GeneOrGeneProduct | denotes | DACH1 |
| T8 | 547-552 | GeneOrGeneProduct | denotes | DACH1 |
| T9 | 672-678 | GeneOrGeneProduct | denotes | growth |
| T10 | 719-726 | GeneOrGeneProduct | denotes | reduced |
| T11 | 750-755 | GeneOrGeneProduct | denotes | DACH1 |
| T12 | 772-777 | GeneOrGeneProduct | denotes | DACH1 |
| T13 | 778-782 | GeneOrGeneProduct | denotes | high |
| T14 | 799-804 | GeneOrGeneProduct | denotes | DACH1 |
| T15 | 839-844 | GeneOrGeneProduct | denotes | DACH1 |
| T16 | 855-860 | GeneOrGeneProduct | denotes | DACH1 |
| T17 | 891-896 | GeneOrGeneProduct | denotes | CD133 |
| T18 | 901-907 | GeneOrGeneProduct | denotes | Nestin |
| T19 | 948-953 | GeneOrGeneProduct | denotes | DACH1 |
| T20 | 954-958 | GeneOrGeneProduct | denotes | high |
| T21 | 1008-1013 | GeneOrGeneProduct | denotes | DACH1 |
| T22 | 1038-1043 | GeneOrGeneProduct | denotes | DACH1 |
| T23 | 1044-1048 | GeneOrGeneProduct | denotes | high |
| T24 | 1096-1101 | GeneOrGeneProduct | denotes | DACH1 |
| T25 | 1227-1253 | GeneOrGeneProduct | denotes | fibroblast growth factor 2 |
| T26 | 1255-1259 | GeneOrGeneProduct | denotes | FGF2 |
| T27 | 1260-1264 | GeneOrGeneProduct | denotes | bFGF |
| T28 | 1269-1286 | GeneOrGeneProduct | denotes | transcriptionally |
| T29 | 1300-1305 | GeneOrGeneProduct | denotes | DACH1 |
| T30 | 1368-1372 | GeneOrGeneProduct | denotes | bFGF |
| T31 | 1437-1442 | GeneOrGeneProduct | denotes | DACH1 |
| T32 | 1443-1447 | GeneOrGeneProduct | denotes | high |
| T33 | 1479-1484 | GeneOrGeneProduct | denotes | DACH1 |
| T34 | 1540-1555 | GeneOrGeneProduct | denotes | transcriptional |
| T35 | 1570-1574 | GeneOrGeneProduct | denotes | bFGF |
| T36 | 1606-1611 | GeneOrGeneProduct | denotes | DACH1 |
| T37 | 1629-1645 | GeneOrGeneProduct | denotes | tumor suppressor |
| T38 | 1676-1682 | GeneOrGeneProduct | denotes | growth |
| T39 | 1717-1721 | GeneOrGeneProduct | denotes | bFGF |
LitCoin-Disease-MeSH
| Id | Subject | Object | Predicate | Lexical cue | originalLabel |
|---|---|---|---|---|---|
| T1 | 42-47 | DiseaseOrPhenotypicFeature | denotes | tumor | D009369 |
| T2 | 71-77 | DiseaseOrPhenotypicFeature | denotes | glioma | D005910 |
| T3 | 118-123 | DiseaseOrPhenotypicFeature | denotes | tumor | D009369 |
| T4 | 156-169 | DiseaseOrPhenotypicFeature | denotes | tumorigenesis | D063646 |
| T5 | 323-335 | DiseaseOrPhenotypicFeature | denotes | glioblastoma | D005909 |
| T6 | 451-457 | DiseaseOrPhenotypicFeature | denotes | glioma | D005910 |
| T7 | 527-533 | DiseaseOrPhenotypicFeature | denotes | glioma | D005910 |
| T8 | 700-706 | DiseaseOrPhenotypicFeature | denotes | tumors | D009369 |
| T9 | 1126-1131 | DiseaseOrPhenotypicFeature | denotes | tumor | D009369 |
| T10 | 1509-1514 | DiseaseOrPhenotypicFeature | denotes | tumor | D009369 |
| T11 | 1629-1634 | DiseaseOrPhenotypicFeature | denotes | tumor | D009369 |
| T12 | 1686-1691 | DiseaseOrPhenotypicFeature | denotes | tumor | D009369 |
| T13 | 1731-1736 | DiseaseOrPhenotypicFeature | denotes | tumor | D009369 |
| T14 | 1760-1766 | DiseaseOrPhenotypicFeature | denotes | glioma | D005910 |
LitCoin-GeneOrGeneProduct-v3
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 26-31 | GeneOrGeneProduct | denotes | DACH1 |
| T2 | 124-134 | GeneOrGeneProduct | denotes | suppressor |
| T3 | 375-380 | GeneOrGeneProduct | denotes | DACH1 |
| T4 | 493-498 | GeneOrGeneProduct | denotes | DACH1 |
| T5 | 547-552 | GeneOrGeneProduct | denotes | DACH1 |
| T6 | 750-755 | GeneOrGeneProduct | denotes | DACH1 |
| T7 | 772-777 | GeneOrGeneProduct | denotes | DACH1 |
| T8 | 799-804 | GeneOrGeneProduct | denotes | DACH1 |
| T9 | 839-844 | GeneOrGeneProduct | denotes | DACH1 |
| T10 | 855-860 | GeneOrGeneProduct | denotes | DACH1 |
| T11 | 891-896 | GeneOrGeneProduct | denotes | CD133 |
| T12 | 901-907 | GeneOrGeneProduct | denotes | Nestin |
| T13 | 948-953 | GeneOrGeneProduct | denotes | DACH1 |
| T14 | 1008-1013 | GeneOrGeneProduct | denotes | DACH1 |
| T15 | 1038-1043 | GeneOrGeneProduct | denotes | DACH1 |
| T16 | 1096-1101 | GeneOrGeneProduct | denotes | DACH1 |
| T17 | 1227-1253 | GeneOrGeneProduct | denotes | fibroblast growth factor 2 |
| T18 | 1255-1259 | GeneOrGeneProduct | denotes | FGF2 |
| T19 | 1260-1264 | GeneOrGeneProduct | denotes | bFGF |
| T20 | 1300-1305 | GeneOrGeneProduct | denotes | DACH1 |
| T21 | 1368-1372 | GeneOrGeneProduct | denotes | bFGF |
| T22 | 1437-1442 | GeneOrGeneProduct | denotes | DACH1 |
| T23 | 1479-1484 | GeneOrGeneProduct | denotes | DACH1 |
| T24 | 1540-1566 | GeneOrGeneProduct | denotes | transcriptional activation |
| T25 | 1570-1574 | GeneOrGeneProduct | denotes | bFGF |
| T26 | 1606-1611 | GeneOrGeneProduct | denotes | DACH1 |
| T27 | 1635-1645 | GeneOrGeneProduct | denotes | suppressor |
| T28 | 1717-1721 | GeneOrGeneProduct | denotes | bFGF |
LitCoin_Mondo_095
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 42-47 | DiseaseOrPhenotypicFeature | denotes | tumor | 0005070 |
| T2 | 71-77 | DiseaseOrPhenotypicFeature | denotes | glioma | 0100342|0021042 |
| T4 | 118-123 | DiseaseOrPhenotypicFeature | denotes | tumor | 0005070 |
| T5 | 323-335 | DiseaseOrPhenotypicFeature | denotes | glioblastoma | 0018177 |
| T6 | 451-457 | DiseaseOrPhenotypicFeature | denotes | glioma | 0100342|0021042 |
| T8 | 527-533 | DiseaseOrPhenotypicFeature | denotes | glioma | 0100342|0021042 |
| T10 | 1126-1131 | DiseaseOrPhenotypicFeature | denotes | tumor | 0005070 |
| T11 | 1509-1514 | DiseaseOrPhenotypicFeature | denotes | tumor | 0005070 |
| T12 | 1629-1634 | DiseaseOrPhenotypicFeature | denotes | tumor | 0005070 |
| T13 | 1686-1691 | DiseaseOrPhenotypicFeature | denotes | tumor | 0005070 |
| T14 | 1731-1736 | DiseaseOrPhenotypicFeature | denotes | tumor | 0005070 |
| T15 | 1760-1766 | DiseaseOrPhenotypicFeature | denotes | glioma | 0100342|0021042 |
LitCoin-MeSH-Disease-2
| Id | Subject | Object | Predicate | Lexical cue | ID: |
|---|---|---|---|---|---|
| T1 | 42-47 | DiseaseOrPhenotypicFeature | denotes | tumor | D009369 |
| T2 | 71-77 | DiseaseOrPhenotypicFeature | denotes | glioma | D005910 |
| T3 | 118-123 | DiseaseOrPhenotypicFeature | denotes | tumor | D009369 |
| T4 | 156-169 | DiseaseOrPhenotypicFeature | denotes | tumorigenesis | D063646 |
| T5 | 323-335 | DiseaseOrPhenotypicFeature | denotes | glioblastoma | D005909 |
| T6 | 451-457 | DiseaseOrPhenotypicFeature | denotes | glioma | D005910 |
| T7 | 527-533 | DiseaseOrPhenotypicFeature | denotes | glioma | D005910 |
| T8 | 700-706 | DiseaseOrPhenotypicFeature | denotes | tumors | DISEASE|D009369 |
| T10 | 1126-1131 | DiseaseOrPhenotypicFeature | denotes | tumor | D009369 |
| T11 | 1509-1514 | DiseaseOrPhenotypicFeature | denotes | tumor | D009369 |
| T12 | 1629-1634 | DiseaseOrPhenotypicFeature | denotes | tumor | D009369 |
| T13 | 1686-1691 | DiseaseOrPhenotypicFeature | denotes | tumor | D009369 |
| T14 | 1731-1736 | DiseaseOrPhenotypicFeature | denotes | tumor | D009369 |
| T15 | 1760-1766 | DiseaseOrPhenotypicFeature | denotes | glioma | D005910 |
LitCoin_CellLine
| Id | Subject | Object | Predicate | Lexical cue | cellosaurus_accession_id |
|---|---|---|---|---|---|
| T1 | 524-526 | CellLine | denotes | Da | CVCL_2015 |
| T2 | 736-738 | CellLine | denotes | Da | CVCL_2015 |
| T3 | 768-771 | CellLine | denotes | U87 | CVCL_0022|CVCL_GP63 |
| T5 | 825-827 | CellLine | denotes | Da | CVCL_2015 |
| T6 | 835-838 | CellLine | denotes | U87 | CVCL_0022|CVCL_GP63 |
| T8 | 851-854 | CellLine | denotes | U87 | CVCL_0022|CVCL_GP63 |
| T10 | 944-947 | CellLine | denotes | U87 | CVCL_0022|CVCL_GP63 |
| T12 | 1004-1007 | CellLine | denotes | U87 | CVCL_0022|CVCL_GP63 |
| T14 | 1034-1037 | CellLine | denotes | U87 | CVCL_0022|CVCL_GP63 |
| T16 | 1433-1436 | CellLine | denotes | U87 | CVCL_GP63|CVCL_0022 |
LitCoin-MONDO_bioort2019
| Id | Subject | Object | Predicate | Lexical cue | #label |
|---|---|---|---|---|---|
| T1 | 42-47 | DiseaseOrPhenotypicFeature | denotes | tumor | D009369 |
| T2 | 71-77 | DiseaseOrPhenotypicFeature | denotes | glioma | D005910 |
| T3 | 118-123 | DiseaseOrPhenotypicFeature | denotes | tumor | D009369 |
| T4 | 156-169 | DiseaseOrPhenotypicFeature | denotes | tumorigenesis | D063646 |
| T5 | 323-335 | DiseaseOrPhenotypicFeature | denotes | glioblastoma | D005909 |
| T6 | 451-457 | DiseaseOrPhenotypicFeature | denotes | glioma | D005910 |
| T7 | 527-533 | DiseaseOrPhenotypicFeature | denotes | glioma | D005910 |
| T8 | 700-706 | DiseaseOrPhenotypicFeature | denotes | tumors | D009369 |
| T9 | 1126-1131 | DiseaseOrPhenotypicFeature | denotes | tumor | D009369 |
| T10 | 1509-1514 | DiseaseOrPhenotypicFeature | denotes | tumor | D009369 |
| T11 | 1629-1634 | DiseaseOrPhenotypicFeature | denotes | tumor | D009369 |
| T12 | 1686-1691 | DiseaseOrPhenotypicFeature | denotes | tumor | D009369 |
| T13 | 1731-1736 | DiseaseOrPhenotypicFeature | denotes | tumor | D009369 |
| T14 | 1760-1766 | DiseaseOrPhenotypicFeature | denotes | glioma | D005910 |
LitCoin-NCBITaxon-2
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 710-714 | OrganismTaxon | denotes | mice |
| T2 | 876-885 | OrganismTaxon | denotes | spheroids |
LitCoin-Chemical-MeSH-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | ID: |
|---|---|---|---|---|---|
| T1 | 611-622 | ChemicalEntity | denotes | doxycycline | D004318|http://purl.obolibrary.org/obo/CHEBI_60648|http://purl.obolibrary.org/obo/CHEBI_50845 |
LitCoin-training-merged
| Id | Subject | Object | Predicate | Lexical cue | #label | ID: | cellosaurus_accession_id |
|---|---|---|---|---|---|---|---|
| T16 | 1433-1436 | CellLine | denotes | U87 | CVCL_GP63|CVCL_0022 | ||
| T14 | 1034-1037 | CellLine | denotes | U87 | CVCL_GP63|CVCL_0022 | ||
| T12 | 1004-1007 | CellLine | denotes | U87 | CVCL_GP63|CVCL_0022 | ||
| T10 | 944-947 | CellLine | denotes | U87 | CVCL_GP63|CVCL_0022 | ||
| T8 | 851-854 | CellLine | denotes | U87 | CVCL_GP63|CVCL_0022 | ||
| T6 | 835-838 | CellLine | denotes | U87 | CVCL_GP63|CVCL_0022 | ||
| T5 | 825-827 | CellLine | denotes | Da | CVCL_2015 | ||
| T3 | 768-771 | CellLine | denotes | U87 | CVCL_GP63|CVCL_0022 | ||
| T2 | 736-738 | CellLine | denotes | Da | CVCL_2015 | ||
| T1 | 524-526 | CellLine | denotes | Da | CVCL_2015 | ||
| T31862 | 611-622 | ChemicalEntity | denotes | doxycycline | http://purl.obolibrary.org/obo/CHEBI_50845|http://purl.obolibrary.org/obo/CHEBI_60648|D004318 | ||
| T28 | 1717-1721 | GeneOrGeneProduct | denotes | bFGF | |||
| T27 | 1635-1645 | GeneOrGeneProduct | denotes | suppressor | |||
| T26 | 1606-1611 | GeneOrGeneProduct | denotes | DACH1 | |||
| T25 | 1570-1574 | GeneOrGeneProduct | denotes | bFGF | |||
| T24 | 1540-1566 | GeneOrGeneProduct | denotes | transcriptional activation | |||
| T23 | 1479-1484 | GeneOrGeneProduct | denotes | DACH1 | |||
| T22 | 1437-1442 | GeneOrGeneProduct | denotes | DACH1 | |||
| T21 | 1368-1372 | GeneOrGeneProduct | denotes | bFGF | |||
| T20 | 1300-1305 | GeneOrGeneProduct | denotes | DACH1 | |||
| T19 | 1260-1264 | GeneOrGeneProduct | denotes | bFGF | |||
| T18 | 1255-1259 | GeneOrGeneProduct | denotes | FGF2 | |||
| T17 | 1227-1253 | GeneOrGeneProduct | denotes | fibroblast growth factor 2 | |||
| T99700 | 1096-1101 | GeneOrGeneProduct | denotes | DACH1 | |||
| T15 | 1038-1043 | GeneOrGeneProduct | denotes | DACH1 | |||
| T29049 | 1008-1013 | GeneOrGeneProduct | denotes | DACH1 | |||
| T13 | 948-953 | GeneOrGeneProduct | denotes | DACH1 | |||
| T71598 | 901-907 | GeneOrGeneProduct | denotes | Nestin | |||
| T11 | 891-896 | GeneOrGeneProduct | denotes | CD133 | |||
| T54017 | 855-860 | GeneOrGeneProduct | denotes | DACH1 | |||
| T9 | 839-844 | GeneOrGeneProduct | denotes | DACH1 | |||
| T87561 | 799-804 | GeneOrGeneProduct | denotes | DACH1 | |||
| T7 | 772-777 | GeneOrGeneProduct | denotes | DACH1 | |||
| T76527 | 750-755 | GeneOrGeneProduct | denotes | DACH1 | |||
| T96835 | 547-552 | GeneOrGeneProduct | denotes | DACH1 | |||
| T4 | 493-498 | GeneOrGeneProduct | denotes | DACH1 | |||
| T61115 | 375-380 | GeneOrGeneProduct | denotes | DACH1 | |||
| T14010 | 124-134 | GeneOrGeneProduct | denotes | suppressor | |||
| T60043 | 26-31 | GeneOrGeneProduct | denotes | DACH1 | |||
| T53270 | 1760-1766 | DiseaseOrPhenotypicFeature | denotes | glioma | D005910 | ||
| T60207 | 1731-1736 | DiseaseOrPhenotypicFeature | denotes | tumor | D009369 | ||
| T823 | 1686-1691 | DiseaseOrPhenotypicFeature | denotes | tumor | D009369 | ||
| T75438 | 1629-1634 | DiseaseOrPhenotypicFeature | denotes | tumor | D009369 | ||
| T69892 | 1509-1514 | DiseaseOrPhenotypicFeature | denotes | tumor | D009369 | ||
| T54992 | 1126-1131 | DiseaseOrPhenotypicFeature | denotes | tumor | D009369 | ||
| T37907 | 700-706 | DiseaseOrPhenotypicFeature | denotes | tumors | D009369 | ||
| T24885 | 527-533 | DiseaseOrPhenotypicFeature | denotes | glioma | D005910 | ||
| T57966 | 451-457 | DiseaseOrPhenotypicFeature | denotes | glioma | D005910 | ||
| T87006 | 323-335 | DiseaseOrPhenotypicFeature | denotes | glioblastoma | D005909 | ||
| T93501 | 156-169 | DiseaseOrPhenotypicFeature | denotes | tumorigenesis | D063646 | ||
| T95705 | 118-123 | DiseaseOrPhenotypicFeature | denotes | tumor | D009369 | ||
| T95403 | 71-77 | DiseaseOrPhenotypicFeature | denotes | glioma | D005910 | ||
| T28779 | 42-47 | DiseaseOrPhenotypicFeature | denotes | tumor | D009369 | ||
| T8308 | 876-885 | OrganismTaxon | denotes | spheroids | |||
| T79526 | 710-714 | OrganismTaxon | denotes | mice |
DisGeNET
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T0 | 493-498 | gene:1602 | denotes | DACH1 |
| T1 | 451-457 | disease:C0017638 | denotes | glioma |
| R1 | T0 | T1 | associated_with | DACH1,glioma |
PubmedHPO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 118-123 | HP_0002664 | denotes | tumor |
| T2 | 323-335 | HP_0100843 | denotes | glioblastoma |
| T3 | 323-347 | HP_0012174 | denotes | glioblastoma multiformes |
| T4 | 451-457 | HP_0009733 | denotes | glioma |
| T5 | 527-533 | HP_0009733 | denotes | glioma |
| T6 | 700-706 | HP_0002664 | denotes | tumors |
| T7 | 1126-1131 | HP_0002664 | denotes | tumor |
| T8 | 1509-1514 | HP_0002664 | denotes | tumor |
| T9 | 1629-1634 | HP_0002664 | denotes | tumor |
| T10 | 1686-1691 | HP_0002664 | denotes | tumor |
| T11 | 1731-1736 | HP_0002664 | denotes | tumor |
| T12 | 1760-1766 | HP_0009733 | denotes | glioma |
DisGeNET5_gene_disease
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 21750150-10#30#35#gene1602 | 1606-1611 | gene1602 | denotes | DACH1 |
| 21750150-10#184#190#diseaseC0017638 | 1760-1766 | diseaseC0017638 | denotes | glioma |
| 30#35#gene1602184#190#diseaseC0017638 | 21750150-10#30#35#gene1602 | 21750150-10#184#190#diseaseC0017638 | associated_with | DACH1,glioma |