PubMed:21738794 / 801-1525 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/21738794","sourcedb":"PubMed","sourceid":"21738794","source_url":"https://www.ncbi.nlm.nih.gov/pubmed/21738794","text":"Here we characterize the specificity of the octenol receptor neuron in the yellow fever mosquito, Aedes aegypti (L.), in vivo using single cell recordings. The octenol neuron is exquisitely sensitive to (R)-(-)-1-octen-3-ol; comparable responses to (S)-(+)-1-octen-3-ol were elicited only at stimulus doses over 100× that required for the (R)-enantiomer. An intermediate response closer to that elicited by the (R)-(-)-enantiomer was elicited by racemic 1-octen-3-ol. Small structural changes in (R)-(-)-1-octen-3-ol resulted in large decreases in responses. Increases in spike activity were also elicited in the octenol neuron by 2-undecanone, a known repellent; other repellents (DEET, IR3535 and picaridin) were inactive.","tracks":[{"project":"PubMed_Structured_Abstracts","denotations":[{"id":"T2","span":{"begin":0,"end":724},"obj":"RESULTS"}],"attributes":[{"subj":"T2","pred":"source","obj":"PubMed_Structured_Abstracts"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"PubMed_Structured_Abstracts","color":"#93eca9","default":true}]}]}}