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PubMed:2170352 JSONTXT

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LitCoin-PubTator-for-Tuning

Id	Subject	Object	Predicate	Lexical cue	tao:has_database_id
2	28-33	ChemicalEntity	denotes	metal	MESH:D008670
3	46-62	ChemicalEntity	denotes	hydroxyl radical	MESH:D017665
19	160-176	ChemicalEntity	denotes	hydroxyl radical	MESH:D017665
20	203-235	ChemicalEntity	denotes	5,5-dimethyl-1-pyrroline N-oxide	MESH:C017245
21	237-241	ChemicalEntity	denotes	DMPO	MESH:C017245
22	250-258	ChemicalEntity	denotes	xanthine	MESH:D019820
23	286-303	ChemicalEntity	denotes	hydrogen peroxide	MESH:D006861
24	335-356	ChemicalEntity	denotes	DMPO-hydroxyl radical
25	451-468	ChemicalEntity	denotes	Hydroxyl radicals	MESH:D017665
26	521-544	ChemicalEntity	denotes	DMPO-superoxide radical
27	608-612	ChemicalEntity	denotes	iron	MESH:D007501
28	799-815	ChemicalEntity	denotes	hydroxyl radical	MESH:D017665
29	851-868	ChemicalEntity	denotes	hydroxyl radicals	MESH:D017665
30	907-924	ChemicalEntity	denotes	hydrogen peroxide	MESH:D006861
31	988-997	ChemicalEntity	denotes	phosphate	MESH:D010710
32	1023-1044	ChemicalEntity	denotes	deferoxamine mesylate	MESH:D003676
33	1126-1131	ChemicalEntity	denotes	metal	MESH:D008670

sentences

Id	Subject	Object	Predicate	Lexical cue
T1	0-94	Sentence	denotes	Evidence against transition metal-independent hydroxyl radical generation by xanthine oxidase.
T2	95-316	Sentence	denotes	It is shown by the use of EPR spectroscopy that formation of the hydroxyl radical adduct with the spin trap 5,5-dimethyl-1-pyrroline N-oxide (DMPO) in the xanthine-xanthine oxidase system is hydrogen peroxide-independent.
T3	317-450	Sentence	denotes	Production of the DMPO-hydroxyl radical adduct is inhibited by superoxide dismutase but is unaffected by purified grades of catalase.
T4	451-635	Sentence	denotes	Hydroxyl radicals are a secondary product of the decomposition of the DMPO-superoxide radical adduct and are also formed as a result of trace metals such as iron present in the buffer.
T5	636-717	Sentence	denotes	These results are in contrast with a recent report (Kuppusamy, P., and Zweier, J.
T6	718-730	Sentence	denotes	W. (1989) J.
T7	731-736	Sentence	denotes	Biol.
T8	737-742	Sentence	denotes	Chem.
T9	743-945	Sentence	denotes	264, 9880-9884) in which the assertion is made that the hydroxyl radical adduct arises from the trapping of hydroxyl radicals generated via the direct reduction of hydrogen peroxide by xanthine oxidase.
T10	946-1178	Sentence	denotes	It is demonstrated here that treatment of phosphate buffer with the chelator deferoxamine mesylate is not in itself sufficient to suppress the effect of contaminating adventitious metal ions in xanthine-xanthine oxidase incubations.
T1	0-94	Sentence	denotes	Evidence against transition metal-independent hydroxyl radical generation by xanthine oxidase.
T2	95-316	Sentence	denotes	It is shown by the use of EPR spectroscopy that formation of the hydroxyl radical adduct with the spin trap 5,5-dimethyl-1-pyrroline N-oxide (DMPO) in the xanthine-xanthine oxidase system is hydrogen peroxide-independent.
T3	317-450	Sentence	denotes	Production of the DMPO-hydroxyl radical adduct is inhibited by superoxide dismutase but is unaffected by purified grades of catalase.
T4	451-635	Sentence	denotes	Hydroxyl radicals are a secondary product of the decomposition of the DMPO-superoxide radical adduct and are also formed as a result of trace metals such as iron present in the buffer.
T5	636-717	Sentence	denotes	These results are in contrast with a recent report (Kuppusamy, P., and Zweier, J.
T6	718-730	Sentence	denotes	W. (1989) J.
T7	731-736	Sentence	denotes	Biol.
T8	737-742	Sentence	denotes	Chem.
T9	743-945	Sentence	denotes	264, 9880-9884) in which the assertion is made that the hydroxyl radical adduct arises from the trapping of hydroxyl radicals generated via the direct reduction of hydrogen peroxide by xanthine oxidase.
T10	946-1178	Sentence	denotes	It is demonstrated here that treatment of phosphate buffer with the chelator deferoxamine mesylate is not in itself sufficient to suppress the effect of contaminating adventitious metal ions in xanthine-xanthine oxidase incubations.

NCBITAXON

Id	Subject	Object	Predicate	Lexical cue	db_id
T1	1014-1022	OrganismTaxon	denotes	chelator	263156