PubMed:21611757
Annnotations
LitCoin-PubTator-for-Tuning
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 5 | 10-13 | GeneOrGeneProduct | denotes | MPO | Gene:4353 |
| 6 | 28-48 | DiseaseOrPhenotypicFeature | denotes | polyarteritis nodosa | MESH:D010488 |
| 7 | 74-80 | DiseaseOrPhenotypicFeature | denotes | otitis | MESH:D010031 |
| 8 | 88-110 | DiseaseOrPhenotypicFeature | denotes | mononeuritis multiplex | MESH:D020422 |
| 9 | 116-135 | DiseaseOrPhenotypicFeature | denotes | acute renal failure | MESH:D058186 |
| 36 | 178-183 | OrganismTaxon | denotes | woman | Tax:9606 |
| 37 | 249-267 | DiseaseOrPhenotypicFeature | denotes | hearing impairment | MESH:D034381 |
| 38 | 295-301 | DiseaseOrPhenotypicFeature | denotes | otitis | MESH:D010031 |
| 39 | 435-443 | DiseaseOrPhenotypicFeature | denotes | deafness | MESH:D003638 |
| 40 | 445-453 | DiseaseOrPhenotypicFeature | denotes | numbness | MESH:D006987 |
| 41 | 455-471 | DiseaseOrPhenotypicFeature | denotes | gait disturbance | MESH:D020233 |
| 42 | 485-492 | DiseaseOrPhenotypicFeature | denotes | fatigue | MESH:D005221 |
| 43 | 722-738 | DiseaseOrPhenotypicFeature | denotes | exudative otitis | MESH:D010031 |
| 44 | 749-758 | DiseaseOrPhenotypicFeature | denotes | sinusitis | MESH:D012852 |
| 45 | 771-795 | DiseaseOrPhenotypicFeature | denotes | Wegener's granulomatosis | MESH:D014890 |
| 46 | 851-860 | DiseaseOrPhenotypicFeature | denotes | granuloma | MESH:D006099 |
| 47 | 874-884 | DiseaseOrPhenotypicFeature | denotes | vasculitis | MESH:D014657 |
| 48 | 971-974 | GeneOrGeneProduct | denotes | MPO | Gene:4353 |
| 49 | 1008-1019 | DiseaseOrPhenotypicFeature | denotes | polyangitis | |
| 50 | 1150-1174 | DiseaseOrPhenotypicFeature | denotes | glomerular abnormalities | MESH:D007674 |
| 51 | 1187-1207 | DiseaseOrPhenotypicFeature | denotes | polyarteritis nodosa | MESH:D010488 |
| 52 | 1259-1277 | ChemicalEntity | denotes | methylprednisolone | MESH:D008775 |
| 53 | 1304-1319 | DiseaseOrPhenotypicFeature | denotes | lacunar infarct | MESH:D059409 |
| 54 | 1342-1361 | DiseaseOrPhenotypicFeature | denotes | cerebral hemorrhage | MESH:D002543 |
| 55 | 1371-1378 | OrganismTaxon | denotes | patient | Tax:9606 |
| 56 | 1428-1446 | DiseaseOrPhenotypicFeature | denotes | fibrinoid necrosis | MESH:D038261 |
| 57 | 1588-1607 | DiseaseOrPhenotypicFeature | denotes | systemic vasculitis | MESH:D056647 |
| 58 | 1668-1675 | OrganismTaxon | denotes | patient | Tax:9606 |
| 59 | 1681-1684 | GeneOrGeneProduct | denotes | MPO | Gene:4353 |
| 60 | 1746-1752 | DiseaseOrPhenotypicFeature | denotes | otitis | MESH:D010031 |
| 61 | 1763-1775 | DiseaseOrPhenotypicFeature | denotes | hearing loss | MESH:D034381 |
LitCoin-Disease-Tuning-1
| Id | Subject | Object | Predicate | Lexical cue | ID: |
|---|---|---|---|---|---|
| T1 | 28-48 | DiseaseOrPhenotypicFeature | denotes | polyarteritis nodosa | D010488 |
| T2 | 74-86 | DiseaseOrPhenotypicFeature | denotes | otitis media | D010033 |
| T3 | 88-110 | DiseaseOrPhenotypicFeature | denotes | mononeuritis multiplex | D020422 |
| T4 | 116-135 | DiseaseOrPhenotypicFeature | denotes | acute renal failure | D058186 |
| T5 | 249-267 | DiseaseOrPhenotypicFeature | denotes | hearing impairment | D034381 |
| T6 | 295-307 | DiseaseOrPhenotypicFeature | denotes | otitis media | D010033 |
| T7 | 435-443 | DiseaseOrPhenotypicFeature | denotes | deafness | D003638 |
| T8 | 445-453 | DiseaseOrPhenotypicFeature | denotes | numbness | D006987 |
| T9 | 485-492 | DiseaseOrPhenotypicFeature | denotes | fatigue | D005221 |
| T10 | 609-621 | DiseaseOrPhenotypicFeature | denotes | inflammatory | DISEASE |
| T11 | 732-744 | DiseaseOrPhenotypicFeature | denotes | otitis media | D010033 |
| T12 | 749-758 | DiseaseOrPhenotypicFeature | denotes | sinusitis | D012852 |
| T13 | 771-795 | DiseaseOrPhenotypicFeature | denotes | Wegener's granulomatosis | D014890 |
| T14 | 851-860 | DiseaseOrPhenotypicFeature | denotes | granuloma | D006099 |
| T15 | 874-884 | DiseaseOrPhenotypicFeature | denotes | vasculitis | D014657 |
| T16 | 1059-1067 | DiseaseOrPhenotypicFeature | denotes | stenosis | D003251 |
| T17 | 1187-1207 | DiseaseOrPhenotypicFeature | denotes | polyarteritis nodosa | D010488 |
| T18 | 1209-1212 | DiseaseOrPhenotypicFeature | denotes | PAN | DISEASE|D010488 |
| T20 | 1304-1319 | DiseaseOrPhenotypicFeature | denotes | lacunar infarct | D059409 |
| T21 | 1342-1361 | DiseaseOrPhenotypicFeature | denotes | cerebral hemorrhage | D002543 |
| T22 | 1379-1383 | DiseaseOrPhenotypicFeature | denotes | died | DISEASE |
| T23 | 1438-1446 | DiseaseOrPhenotypicFeature | denotes | necrosis | D009336 |
| T24 | 1588-1607 | DiseaseOrPhenotypicFeature | denotes | systemic vasculitis | D056647 |
| T25 | 1637-1640 | DiseaseOrPhenotypicFeature | denotes | PAN | DISEASE|D010488 |
| T27 | 1699-1702 | DiseaseOrPhenotypicFeature | denotes | PAN | DISEASE|D010488 |
| T29 | 1746-1758 | DiseaseOrPhenotypicFeature | denotes | otitis media | D010033 |
| T30 | 1763-1775 | DiseaseOrPhenotypicFeature | denotes | hearing loss | D034381 |
| T31 | 1808-1811 | DiseaseOrPhenotypicFeature | denotes | PAN | DISEASE|D010488 |
LitEisuke
| Id | Subject | Object | Predicate | Lexical cue | #label |
|---|---|---|---|---|---|
| T1 | 28-48 | DiseaseOrPhenotypicFeature | denotes | polyarteritis nodosa | D010488 |
| T2 | 74-86 | DiseaseOrPhenotypicFeature | denotes | otitis media | D010033 |
| T3 | 88-110 | DiseaseOrPhenotypicFeature | denotes | mononeuritis multiplex | D020422 |
| T4 | 116-135 | DiseaseOrPhenotypicFeature | denotes | acute renal failure | D058186 |
| T5 | 249-267 | DiseaseOrPhenotypicFeature | denotes | hearing impairment | D034381 |
| T6 | 295-307 | DiseaseOrPhenotypicFeature | denotes | otitis media | D010033 |
| T7 | 435-443 | DiseaseOrPhenotypicFeature | denotes | deafness | D003638 |
| T8 | 445-453 | DiseaseOrPhenotypicFeature | denotes | numbness | D006987 |
| T9 | 485-492 | DiseaseOrPhenotypicFeature | denotes | fatigue | D005221 |
| T10 | 732-744 | DiseaseOrPhenotypicFeature | denotes | otitis media | D010033 |
| T11 | 749-758 | DiseaseOrPhenotypicFeature | denotes | sinusitis | D012852 |
| T12 | 771-795 | DiseaseOrPhenotypicFeature | denotes | Wegener's granulomatosis | D014890 |
| T13 | 851-860 | DiseaseOrPhenotypicFeature | denotes | granuloma | D006099 |
| T14 | 874-884 | DiseaseOrPhenotypicFeature | denotes | vasculitis | D014657 |
| T15 | 1059-1067 | DiseaseOrPhenotypicFeature | denotes | stenosis | D003251 |
| T16 | 1187-1207 | DiseaseOrPhenotypicFeature | denotes | polyarteritis nodosa | D010488 |
| T17 | 1209-1212 | DiseaseOrPhenotypicFeature | denotes | PAN | DISEASE|D010488 |
| T19 | 1304-1319 | DiseaseOrPhenotypicFeature | denotes | lacunar infarct | D059409 |
| T20 | 1342-1361 | DiseaseOrPhenotypicFeature | denotes | cerebral hemorrhage | D002543 |
| T21 | 1379-1383 | DiseaseOrPhenotypicFeature | denotes | died | DISEASE |
| T22 | 1588-1607 | DiseaseOrPhenotypicFeature | denotes | systemic vasculitis | D056647 |
| T23 | 1637-1640 | DiseaseOrPhenotypicFeature | denotes | PAN | DISEASE|D010488 |
| T25 | 1699-1702 | DiseaseOrPhenotypicFeature | denotes | PAN | DISEASE|D010488 |
| T27 | 1746-1758 | DiseaseOrPhenotypicFeature | denotes | otitis media | D010033 |
| T28 | 1763-1775 | DiseaseOrPhenotypicFeature | denotes | hearing loss | D034381 |
| T29 | 1808-1811 | DiseaseOrPhenotypicFeature | denotes | PAN | DISEASE|D010488 |
PubmedHPO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 249-267 | HP_0000365 | denotes | hearing impairment |
| T2 | 435-443 | HP_0000365 | denotes | deafness |
| T3 | 455-471 | HP_0001288 | denotes | gait disturbance |
| T4 | 485-492 | HP_0012378 | denotes | fatigue |
| T5 | 781-795 | HP_0002955 | denotes | granulomatosis |
| T6 | 1073-1086 | HP_0012327 | denotes | celiac artery |
| T7 | 1342-1361 | HP_0001342 | denotes | cerebral hemorrhage |
| T8 | 1763-1775 | HP_0000365 | denotes | hearing loss |
Allie
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| SS1_21611757_5_0 | 676-695 | expanded | denotes | computed tomography |
| SS2_21611757_5_0 | 697-699 | abbr | denotes | CT |
| SS1_21611757_8_0 | 918-969 | expanded | denotes | myeloperoxidase-antineutrophil cytoplasmic antibody |
| SS2_21611757_8_0 | 971-979 | abbr | denotes | MPO-ANCA |
| SS1_21611757_8_1 | 996-1019 | expanded | denotes | microscopic polyangitis |
| SS2_21611757_8_1 | 1021-1024 | abbr | denotes | MPA |
| SS1_21611757_10_0 | 1187-1207 | expanded | denotes | polyarteritis nodosa |
| SS2_21611757_10_0 | 1209-1212 | abbr | denotes | PAN |
| AE1_21611757_5_0 | SS1_21611757_5_0 | SS2_21611757_5_0 | abbreviatedTo | computed tomography,CT |
| AE1_21611757_8_0 | SS1_21611757_8_0 | SS2_21611757_8_0 | abbreviatedTo | myeloperoxidase-antineutrophil cytoplasmic antibody,MPO-ANCA |
| AE1_21611757_8_1 | SS1_21611757_8_1 | SS2_21611757_8_1 | abbreviatedTo | microscopic polyangitis,MPA |
| AE1_21611757_10_0 | SS1_21611757_10_0 | SS2_21611757_10_0 | abbreviatedTo | polyarteritis nodosa,PAN |
UBERON-AE
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| PD-UBERON-AE-B_T1 | 64-73 | http://purl.obolibrary.org/obo/UBERON_0007780 | denotes | exudative |
| PD-UBERON-AE-B_T2 | 285-294 | http://purl.obolibrary.org/obo/UBERON_0007780 | denotes | exudative |
| PD-UBERON-AE-B_T3 | 722-731 | http://purl.obolibrary.org/obo/UBERON_0007780 | denotes | exudative |
| PD-UBERON-AE-B_T4 | 1736-1745 | http://purl.obolibrary.org/obo/UBERON_0007780 | denotes | exudative |
| PD-UBERON-AE-B_T5 | 1073-1086 | http://purl.obolibrary.org/obo/UBERON_0001640 | denotes | celiac artery |
| PD-UBERON-AE-B_T6 | 1080-1086 | http://purl.obolibrary.org/obo/UBERON_0001637 | denotes | artery |
| PD-UBERON-AE-B_T7 | 1524-1532 | http://purl.obolibrary.org/obo/UBERON_0001637 | denotes | arteries |
| PD-UBERON-AE-B_T8 | 1545-1551 | http://purl.obolibrary.org/obo/UBERON_0000062 | denotes | organs |
PubCasesHPO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| TI1 | 74-86 | HP:0000388 | denotes | otitis media |
| AB1 | 249-267 | HP:0000365 | denotes | hearing impairment |
| AB2 | 295-307 | HP:0000388 | denotes | otitis media |
| AB3 | 455-471 | HP:0001288 | denotes | gait disturbance |
| AB4 | 485-492 | HP:0012378 | denotes | fatigue |
| AB5 | 732-744 | HP:0000388 | denotes | otitis media |
| AB6 | 749-758 | HP:0000246 | denotes | sinusitis |
| AB7 | 781-795 | HP:0002955 | denotes | granulomatosis |
| AB8 | 874-884 | HP:0002633 | denotes | vasculitis |
| AB9 | 1342-1361 | HP:0001342 | denotes | cerebral hemorrhage |
| AB10 | 1597-1607 | HP:0002633 | denotes | vasculitis |
| AB11 | 1746-1758 | HP:0000388 | denotes | otitis media |
PubCasesORDO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| TI1 | 28-48 | ORDO:767 | denotes | polyarteritis nodosa |
| AB1 | 1187-1207 | ORDO:767 | denotes | polyarteritis nodosa |
| AB2 | 1209-1212 | ORDO:767 | denotes | PAN |
| AB3 | 1637-1640 | ORDO:767 | denotes | PAN |
| AB4 | 1699-1702 | ORDO:767 | denotes | PAN |
| AB5 | 1808-1811 | ORDO:767 | denotes | PAN |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| TextSentencer_T1 | 0-136 | Sentence | denotes | A case of MPO-ANCA-positive polyarteritis nodosa complicated by exudative otitis media, mononeuritis multiplex, and acute renal failure. |
| TextSentencer_T2 | 137-385 | Sentence | denotes | In December 2008, a 69-year-old Japanese woman was admitted to the Department of Otorhinolaryngology because of hearing impairment due to bilateral exudative otitis media, and was discharged without complete recovery despite conventional treatment. |
| TextSentencer_T3 | 386-493 | Sentence | denotes | Two weeks later, she was readmitted for worsened deafness, numbness, gait disturbance, and general fatigue. |
| TextSentencer_T4 | 494-555 | Sentence | denotes | She was referred to our department for general investigation. |
| TextSentencer_T5 | 556-667 | Sentence | denotes | On admission, laboratory examination revealed severe inflammatory signs and active nephritic urinary sediments. |
| TextSentencer_T6 | 668-759 | Sentence | denotes | Cranial computed tomography (CT) revealed progressive exudative otitis media and sinusitis. |
| TextSentencer_T7 | 760-810 | Sentence | denotes | Initially, Wegener's granulomatosis was suspected. |
| TextSentencer_T8 | 811-885 | Sentence | denotes | Nasal cavity biopsy, however, showed no granuloma formation or vasculitis. |
| TextSentencer_T9 | 886-1026 | Sentence | denotes | Serology revealed high titer of myeloperoxidase-antineutrophil cytoplasmic antibody (MPO-ANCA), suggestive of microscopic polyangitis (MPA). |
| TextSentencer_T10 | 1027-1175 | Sentence | denotes | However, contrast CT identified stenosis of a celiac artery, and renal biopsy showed tubulointerstitial changes with minor glomerular abnormalities. |
| TextSentencer_T11 | 1176-1292 | Sentence | denotes | Therefore, polyarteritis nodosa (PAN) was suspected and treatment with intravenous methylprednisolone was initiated. |
| TextSentencer_T12 | 1293-1410 | Sentence | denotes | However, a lacunar infarct developed followed by cerebral hemorrhage, and the patient died 19 days after readmission. |
| TextSentencer_T13 | 1411-1552 | Sentence | denotes | Autopsy revealed fibrinoid necrosis, neutrophilic infiltration, and giant cell reaction in small to medium-sized arteries in multiple organs. |
| TextSentencer_T14 | 1553-1641 | Sentence | denotes | These findings led to diagnosis of systemic vasculitis anatomically compatible with PAN. |
| TextSentencer_T15 | 1642-1812 | Sentence | denotes | This was a rare case of a patient with MPO-ANCA-positive PAN who may have developed bilateral exudative otitis media and hearing loss as the initial manifestation of PAN. |
| T1 | 0-136 | Sentence | denotes | A case of MPO-ANCA-positive polyarteritis nodosa complicated by exudative otitis media, mononeuritis multiplex, and acute renal failure. |
| T2 | 137-385 | Sentence | denotes | In December 2008, a 69-year-old Japanese woman was admitted to the Department of Otorhinolaryngology because of hearing impairment due to bilateral exudative otitis media, and was discharged without complete recovery despite conventional treatment. |
| T3 | 386-493 | Sentence | denotes | Two weeks later, she was readmitted for worsened deafness, numbness, gait disturbance, and general fatigue. |
| T4 | 494-555 | Sentence | denotes | She was referred to our department for general investigation. |
| T5 | 556-667 | Sentence | denotes | On admission, laboratory examination revealed severe inflammatory signs and active nephritic urinary sediments. |
| T6 | 668-759 | Sentence | denotes | Cranial computed tomography (CT) revealed progressive exudative otitis media and sinusitis. |
| T7 | 760-810 | Sentence | denotes | Initially, Wegener's granulomatosis was suspected. |
| T8 | 811-885 | Sentence | denotes | Nasal cavity biopsy, however, showed no granuloma formation or vasculitis. |
| T9 | 886-1026 | Sentence | denotes | Serology revealed high titer of myeloperoxidase-antineutrophil cytoplasmic antibody (MPO-ANCA), suggestive of microscopic polyangitis (MPA). |
| T10 | 1027-1175 | Sentence | denotes | However, contrast CT identified stenosis of a celiac artery, and renal biopsy showed tubulointerstitial changes with minor glomerular abnormalities. |
| T11 | 1176-1292 | Sentence | denotes | Therefore, polyarteritis nodosa (PAN) was suspected and treatment with intravenous methylprednisolone was initiated. |
| T12 | 1293-1410 | Sentence | denotes | However, a lacunar infarct developed followed by cerebral hemorrhage, and the patient died 19 days after readmission. |
| T13 | 1411-1552 | Sentence | denotes | Autopsy revealed fibrinoid necrosis, neutrophilic infiltration, and giant cell reaction in small to medium-sized arteries in multiple organs. |
| T14 | 1553-1641 | Sentence | denotes | These findings led to diagnosis of systemic vasculitis anatomically compatible with PAN. |
| T15 | 1642-1812 | Sentence | denotes | This was a rare case of a patient with MPO-ANCA-positive PAN who may have developed bilateral exudative otitis media and hearing loss as the initial manifestation of PAN. |
performance-test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| PD-UBERON-AE-B_T1 | 1080-1086 | http://purl.obolibrary.org/obo/UBERON_0001637 | denotes | artery |
| PD-UBERON-AE-B_T2 | 1524-1532 | http://purl.obolibrary.org/obo/UBERON_0001637 | denotes | arteries |
| PD-UBERON-AE-B_T3 | 1545-1551 | http://purl.obolibrary.org/obo/UBERON_0000062 | denotes | organs |
| PD-UBERON-AE-B_T4 | 64-73 | http://purl.obolibrary.org/obo/UBERON_0007780 | denotes | exudative |
| PD-UBERON-AE-B_T5 | 285-294 | http://purl.obolibrary.org/obo/UBERON_0007780 | denotes | exudative |
| PD-UBERON-AE-B_T6 | 722-731 | http://purl.obolibrary.org/obo/UBERON_0007780 | denotes | exudative |
| PD-UBERON-AE-B_T7 | 1736-1745 | http://purl.obolibrary.org/obo/UBERON_0007780 | denotes | exudative |
| PD-UBERON-AE-B_T8 | 811-823 | http://purl.obolibrary.org/obo/UBERON_0001707 | denotes | Nasal cavity |
| PD-UBERON-AE-B_T9 | 1073-1086 | http://purl.obolibrary.org/obo/UBERON_0001640 | denotes | celiac artery |