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GlyCosmos15-Species

Id Subject Object Predicate Lexical cue
20 486-499 Species denotes rat glioma C6
30 1497-1510 Species denotes rat glioma C6

GlyCosmos6-Glycan-Motif-Image

Id Subject Object Predicate Lexical cue image
T1 47-50 Glycan_Motif denotes GM1 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G48558GR|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G46613JI
T3 118-121 Glycan_Motif denotes GM1 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G48558GR|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G46613JI
T5 516-519 Glycan_Motif denotes GM1 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G48558GR|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G46613JI
T7 549-552 Glycan_Motif denotes GM1 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G48558GR|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G46613JI
T9 881-884 Glycan_Motif denotes GM1 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G48558GR|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G46613JI
T11 920-923 Glycan_Motif denotes GM1 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G48558GR|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G46613JI
T13 1440-1443 Glycan_Motif denotes GM1 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G48558GR|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G46613JI
T15 1716-1719 Glycan_Motif denotes GM1 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G48558GR|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G46613JI

sentences

Id Subject Object Predicate Lexical cue
T1 0-46 Sentence denotes Generation of cell surface neoganglioproteins.
T2 47-117 Sentence denotes GM1-neoganglioproteins are non-functional receptors for cholera toxin.
T3 118-369 Sentence denotes GM1 (II3Neu5Ac-GgOse4Cer)-oligosaccharide was prepared from the ganglioside by ozonolysis and alkaline fragmentation, reductively aminated and coupled to the heterobifunctional cross-linker succinimidyl 4-(N-maleimidomethyl) cyclohexane-1-carboxylate.
T4 370-530 Sentence denotes The resulting derivative reacted with free sulfhydryl groups and readily cross-linked to cell surface components on rat glioma C6 cells which are GM1-deficient.
T5 531-701 Sentence denotes Attachment of the GM1-oligosaccharide derivative, which was monitored by increased binding of 125I-cholera toxin to the cells, was both time- and concentration-dependent.
T6 702-823 Sentence denotes Prior treatment of the cells with dithiothreitol enhanced the attachment by generating additional free sulfhydryl groups.
T7 824-936 Sentence denotes The affinity of cholera toxin for cells treated with the GM1-oligosaccharide derivative or with GM1 was similar.
T8 937-1022 Sentence denotes The nature of the newly generated toxin receptors was determined by Western blotting.
T9 1023-1267 Sentence denotes Membranes from derivatized cells were separated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis, and the resolved components were electrophoretically transferred to a nitrocellulose sheet which was overlain with 125I-cholera toxin.
T10 1268-1361 Sentence denotes The toxin bound to a wide variety of membrane proteins, most of which were trypsin-sensitive.
T11 1362-1426 Sentence denotes No such binding was observed using membranes from control cells.
T12 1427-1685 Sentence denotes Although the GM1-neoganglioproteins newly generated on the surface of rat glioma C6 cells readily bound cholera toxin, the cells did not become more responsive to the toxin as measured by increased production of cyclic AMP or activation of adenylate cyclase.
T13 1686-1758 Sentence denotes In contrast, cells exposed to GM1 became highly responsive to the toxin.
T14 1759-1866 Sentence denotes Thus, neoganglioproteins on the cell surface appear to behave as nonfunctional receptors for cholera toxin.
T1 0-46 Sentence denotes Generation of cell surface neoganglioproteins.
T2 47-117 Sentence denotes GM1-neoganglioproteins are non-functional receptors for cholera toxin.
T3 118-369 Sentence denotes GM1 (II3Neu5Ac-GgOse4Cer)-oligosaccharide was prepared from the ganglioside by ozonolysis and alkaline fragmentation, reductively aminated and coupled to the heterobifunctional cross-linker succinimidyl 4-(N-maleimidomethyl) cyclohexane-1-carboxylate.
T4 370-530 Sentence denotes The resulting derivative reacted with free sulfhydryl groups and readily cross-linked to cell surface components on rat glioma C6 cells which are GM1-deficient.
T5 531-701 Sentence denotes Attachment of the GM1-oligosaccharide derivative, which was monitored by increased binding of 125I-cholera toxin to the cells, was both time- and concentration-dependent.
T6 702-823 Sentence denotes Prior treatment of the cells with dithiothreitol enhanced the attachment by generating additional free sulfhydryl groups.
T7 824-936 Sentence denotes The affinity of cholera toxin for cells treated with the GM1-oligosaccharide derivative or with GM1 was similar.
T8 937-1022 Sentence denotes The nature of the newly generated toxin receptors was determined by Western blotting.
T9 1023-1267 Sentence denotes Membranes from derivatized cells were separated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis, and the resolved components were electrophoretically transferred to a nitrocellulose sheet which was overlain with 125I-cholera toxin.
T10 1268-1361 Sentence denotes The toxin bound to a wide variety of membrane proteins, most of which were trypsin-sensitive.
T11 1362-1426 Sentence denotes No such binding was observed using membranes from control cells.
T12 1427-1685 Sentence denotes Although the GM1-neoganglioproteins newly generated on the surface of rat glioma C6 cells readily bound cholera toxin, the cells did not become more responsive to the toxin as measured by increased production of cyclic AMP or activation of adenylate cyclase.
T13 1686-1758 Sentence denotes In contrast, cells exposed to GM1 became highly responsive to the toxin.
T14 1759-1866 Sentence denotes Thus, neoganglioproteins on the cell surface appear to behave as nonfunctional receptors for cholera toxin.

GlyCosmos6-Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 47-50 https://glytoucan.org/Structures/Glycans/G46613JI denotes GM1
T2 47-50 https://glytoucan.org/Structures/Glycans/G48558GR denotes GM1
T3 118-121 https://glytoucan.org/Structures/Glycans/G46613JI denotes GM1
T4 118-121 https://glytoucan.org/Structures/Glycans/G48558GR denotes GM1
T5 516-519 https://glytoucan.org/Structures/Glycans/G46613JI denotes GM1
T6 516-519 https://glytoucan.org/Structures/Glycans/G48558GR denotes GM1
T7 549-552 https://glytoucan.org/Structures/Glycans/G46613JI denotes GM1
T8 549-552 https://glytoucan.org/Structures/Glycans/G48558GR denotes GM1
T9 881-884 https://glytoucan.org/Structures/Glycans/G46613JI denotes GM1
T10 881-884 https://glytoucan.org/Structures/Glycans/G48558GR denotes GM1
T11 920-923 https://glytoucan.org/Structures/Glycans/G46613JI denotes GM1
T12 920-923 https://glytoucan.org/Structures/Glycans/G48558GR denotes GM1
T13 1440-1443 https://glytoucan.org/Structures/Glycans/G46613JI denotes GM1
T14 1440-1443 https://glytoucan.org/Structures/Glycans/G48558GR denotes GM1
T15 1716-1719 https://glytoucan.org/Structures/Glycans/G46613JI denotes GM1
T16 1716-1719 https://glytoucan.org/Structures/Glycans/G48558GR denotes GM1

Glycosmos6-GlycoEpitope

Id Subject Object Predicate Lexical cue
T1 47-50 http://www.glycoepitope.jp/epitopes/EP0050 denotes GM1
T2 118-121 http://www.glycoepitope.jp/epitopes/EP0050 denotes GM1
T3 516-519 http://www.glycoepitope.jp/epitopes/EP0050 denotes GM1
T4 549-552 http://www.glycoepitope.jp/epitopes/EP0050 denotes GM1
T5 881-884 http://www.glycoepitope.jp/epitopes/EP0050 denotes GM1
T6 920-923 http://www.glycoepitope.jp/epitopes/EP0050 denotes GM1
T7 1440-1443 http://www.glycoepitope.jp/epitopes/EP0050 denotes GM1
T8 1716-1719 http://www.glycoepitope.jp/epitopes/EP0050 denotes GM1

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 490-496 HP_0009733 denotes glioma
T2 1501-1507 HP_0009733 denotes glioma

GlyCosmos15-Glycan

Id Subject Object Predicate Lexical cue image
T1 47-50 Glycan denotes GM1 https://api.glycosmos.org/wurcs2image/latest/png/binary/G48558GR
T2 118-121 Glycan denotes GM1 https://api.glycosmos.org/wurcs2image/latest/png/binary/G48558GR
T3 516-519 Glycan denotes GM1 https://api.glycosmos.org/wurcs2image/latest/png/binary/G48558GR
T4 549-552 Glycan denotes GM1 https://api.glycosmos.org/wurcs2image/latest/png/binary/G48558GR
T5 881-884 Glycan denotes GM1 https://api.glycosmos.org/wurcs2image/latest/png/binary/G48558GR
T6 920-923 Glycan denotes GM1 https://api.glycosmos.org/wurcs2image/latest/png/binary/G48558GR
T7 1440-1443 Glycan denotes GM1 https://api.glycosmos.org/wurcs2image/latest/png/binary/G48558GR
T8 1716-1719 Glycan denotes GM1 https://api.glycosmos.org/wurcs2image/latest/png/binary/G48558GR

mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 103-110 Disease denotes cholera http://purl.obolibrary.org/obo/MONDO_0015766
T2 490-496 Disease denotes glioma http://purl.obolibrary.org/obo/MONDO_0021042
T3 630-637 Disease denotes cholera http://purl.obolibrary.org/obo/MONDO_0015766
T4 840-847 Disease denotes cholera http://purl.obolibrary.org/obo/MONDO_0015766
T5 1253-1260 Disease denotes cholera http://purl.obolibrary.org/obo/MONDO_0015766
T6 1501-1507 Disease denotes glioma http://purl.obolibrary.org/obo/MONDO_0021042
T7 1531-1538 Disease denotes cholera http://purl.obolibrary.org/obo/MONDO_0015766
T8 1852-1859 Disease denotes cholera http://purl.obolibrary.org/obo/MONDO_0015766

HP-phenotype

Id Subject Object Predicate Lexical cue hp_id
T1 490-496 Phenotype denotes glioma HP:0009733
T2 1501-1507 Phenotype denotes glioma HP:0009733

Glycan-GlyCosmos

Id Subject Object Predicate Lexical cue image
T1 47-50 Glycan denotes GM1 https://api.glycosmos.org/wurcs2image/latest/png/binary/G48558GR
T2 118-121 Glycan denotes GM1 https://api.glycosmos.org/wurcs2image/latest/png/binary/G48558GR
T3 516-519 Glycan denotes GM1 https://api.glycosmos.org/wurcs2image/latest/png/binary/G48558GR
T4 549-552 Glycan denotes GM1 https://api.glycosmos.org/wurcs2image/latest/png/binary/G48558GR
T5 881-884 Glycan denotes GM1 https://api.glycosmos.org/wurcs2image/latest/png/binary/G48558GR
T6 920-923 Glycan denotes GM1 https://api.glycosmos.org/wurcs2image/latest/png/binary/G48558GR
T7 1440-1443 Glycan denotes GM1 https://api.glycosmos.org/wurcs2image/latest/png/binary/G48558GR
T8 1716-1719 Glycan denotes GM1 https://api.glycosmos.org/wurcs2image/latest/png/binary/G48558GR

GlyCosmos-GlycoEpitope

Id Subject Object Predicate Lexical cue glycoepitope_id
T1 47-50 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes GM1 http://www.glycoepitope.jp/epitopes/EP0050
T2 118-121 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes GM1 http://www.glycoepitope.jp/epitopes/EP0050
T3 516-519 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes GM1 http://www.glycoepitope.jp/epitopes/EP0050
T4 549-552 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes GM1 http://www.glycoepitope.jp/epitopes/EP0050
T5 881-884 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes GM1 http://www.glycoepitope.jp/epitopes/EP0050
T6 920-923 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes GM1 http://www.glycoepitope.jp/epitopes/EP0050
T7 1440-1443 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes GM1 http://www.glycoepitope.jp/epitopes/EP0050
T8 1716-1719 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes GM1 http://www.glycoepitope.jp/epitopes/EP0050

GlyCosmos15-HP

Id Subject Object Predicate Lexical cue hp_id
T1 490-496 Phenotype denotes glioma HP:0009733
T2 1501-1507 Phenotype denotes glioma HP:0009733

GlyCosmos15-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 103-110 Disease denotes cholera MONDO:0015766
T2 490-496 Disease denotes glioma MONDO:0021042|MONDO:0100342
T4 630-637 Disease denotes cholera MONDO:0015766
T5 840-847 Disease denotes cholera MONDO:0015766
T6 1253-1260 Disease denotes cholera MONDO:0015766
T7 1501-1507 Disease denotes glioma MONDO:0021042|MONDO:0100342
T9 1531-1538 Disease denotes cholera MONDO:0015766
T10 1852-1859 Disease denotes cholera MONDO:0015766

GlyCosmos15-GlycoEpitope

Id Subject Object Predicate Lexical cue glycoepitope_id
T1 47-50 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes GM1 http://www.glycoepitope.jp/epitopes/EP0050
T2 118-121 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes GM1 http://www.glycoepitope.jp/epitopes/EP0050
T3 516-519 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes GM1 http://www.glycoepitope.jp/epitopes/EP0050
T4 549-552 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes GM1 http://www.glycoepitope.jp/epitopes/EP0050
T5 881-884 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes GM1 http://www.glycoepitope.jp/epitopes/EP0050
T6 920-923 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes GM1 http://www.glycoepitope.jp/epitopes/EP0050
T7 1440-1443 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes GM1 http://www.glycoepitope.jp/epitopes/EP0050
T8 1716-1719 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes GM1 http://www.glycoepitope.jp/epitopes/EP0050

GlyCosmos15-Sentences

Id Subject Object Predicate Lexical cue
T1 0-46 Sentence denotes Generation of cell surface neoganglioproteins.
T2 47-117 Sentence denotes GM1-neoganglioproteins are non-functional receptors for cholera toxin.
T3 118-369 Sentence denotes GM1 (II3Neu5Ac-GgOse4Cer)-oligosaccharide was prepared from the ganglioside by ozonolysis and alkaline fragmentation, reductively aminated and coupled to the heterobifunctional cross-linker succinimidyl 4-(N-maleimidomethyl) cyclohexane-1-carboxylate.
T4 370-530 Sentence denotes The resulting derivative reacted with free sulfhydryl groups and readily cross-linked to cell surface components on rat glioma C6 cells which are GM1-deficient.
T5 531-701 Sentence denotes Attachment of the GM1-oligosaccharide derivative, which was monitored by increased binding of 125I-cholera toxin to the cells, was both time- and concentration-dependent.
T6 702-823 Sentence denotes Prior treatment of the cells with dithiothreitol enhanced the attachment by generating additional free sulfhydryl groups.
T7 824-936 Sentence denotes The affinity of cholera toxin for cells treated with the GM1-oligosaccharide derivative or with GM1 was similar.
T8 937-1022 Sentence denotes The nature of the newly generated toxin receptors was determined by Western blotting.
T9 1023-1267 Sentence denotes Membranes from derivatized cells were separated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis, and the resolved components were electrophoretically transferred to a nitrocellulose sheet which was overlain with 125I-cholera toxin.
T10 1268-1361 Sentence denotes The toxin bound to a wide variety of membrane proteins, most of which were trypsin-sensitive.
T11 1362-1426 Sentence denotes No such binding was observed using membranes from control cells.
T12 1427-1685 Sentence denotes Although the GM1-neoganglioproteins newly generated on the surface of rat glioma C6 cells readily bound cholera toxin, the cells did not become more responsive to the toxin as measured by increased production of cyclic AMP or activation of adenylate cyclase.
T13 1686-1758 Sentence denotes In contrast, cells exposed to GM1 became highly responsive to the toxin.
T14 1759-1866 Sentence denotes Thus, neoganglioproteins on the cell surface appear to behave as nonfunctional receptors for cholera toxin.

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 486-489 OrganismTaxon denotes rat 10114|10116
T3 1497-1500 OrganismTaxon denotes rat 10114|10116

GlyCosmos15-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 1305-1313 Body_part denotes membrane http://purl.obolibrary.org/obo/GO_0016020|http://purl.obolibrary.org/obo/UBERON_0000094|http://purl.obolibrary.org/obo/UBERON_0000158
T4 1397-1406 Body_part denotes membranes http://purl.obolibrary.org/obo/GO_0016020|http://purl.obolibrary.org/obo/UBERON_0000094|http://purl.obolibrary.org/obo/UBERON_0000158

GlyCosmos15-FMA

Id Subject Object Predicate Lexical cue db_id
T1 14-26 Body_part denotes cell surface FMA:67653
T2 459-471 Body_part denotes cell surface FMA:67653
T3 1791-1803 Body_part denotes cell surface FMA:67653

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 1305-1313 Body_part denotes membrane http://purl.obolibrary.org/obo/GO_0016020|http://purl.obolibrary.org/obo/UBERON_0000094|http://purl.obolibrary.org/obo/UBERON_0000158
T4 1397-1406 Body_part denotes membranes http://purl.obolibrary.org/obo/GO_0016020|http://purl.obolibrary.org/obo/UBERON_0000094|http://purl.obolibrary.org/obo/UBERON_0000158