PubMed:21507905 / 392-814 JSONTXT

{"project":"Glycan-Motif","denotations":[{"id":"T9","span":{"begin":225,"end":228},"obj":"https://glytoucan.org/Structures/Glycans/G81928IQ"},{"id":"T10","span":{"begin":225,"end":228},"obj":"https://glytoucan.org/Structures/Glycans/G98544DH"}],"text":"In order to investigate the balance between surface and intracellular expression and synthesis and degradation of these glycosphingolipids in human lymphocytes of various differentiation stages, we analyzed (i) expression of GD3 molecules on native T and B cells and thymocytes by flow cytometry and (ii) activity and regulation of possible key enzymes for CD60a,b,c synthesis and degradation at the transcriptional level."}

{"project":"GlyCosmos6-Glycan-Motif-Image","denotations":[{"id":"T10","span":{"begin":225,"end":228},"obj":"Glycan_Motif"}],"attributes":[{"id":"A10","pred":"image","subj":"T10","obj":"https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G98544DH"},{"id":"A11","pred":"image","subj":"T10","obj":"https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81928IQ"}],"text":"In order to investigate the balance between surface and intracellular expression and synthesis and degradation of these glycosphingolipids in human lymphocytes of various differentiation stages, we analyzed (i) expression of GD3 molecules on native T and B cells and thymocytes by flow cytometry and (ii) activity and regulation of possible key enzymes for CD60a,b,c synthesis and degradation at the transcriptional level."}

{"project":"sentences","denotations":[{"id":"TextSentencer_T4","span":{"begin":0,"end":422},"obj":"Sentence"},{"id":"T4","span":{"begin":0,"end":422},"obj":"Sentence"},{"id":"T4","span":{"begin":0,"end":422},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"In order to investigate the balance between surface and intracellular expression and synthesis and degradation of these glycosphingolipids in human lymphocytes of various differentiation stages, we analyzed (i) expression of GD3 molecules on native T and B cells and thymocytes by flow cytometry and (ii) activity and regulation of possible key enzymes for CD60a,b,c synthesis and degradation at the transcriptional level."}

{"project":"GlyCosmos6-Glycan-Motif-Structure","denotations":[{"id":"T10","span":{"begin":225,"end":228},"obj":"https://glytoucan.org/Structures/Glycans/G81928IQ"},{"id":"T11","span":{"begin":225,"end":228},"obj":"https://glytoucan.org/Structures/Glycans/G98544DH"}],"text":"In order to investigate the balance between surface and intracellular expression and synthesis and degradation of these glycosphingolipids in human lymphocytes of various differentiation stages, we analyzed (i) expression of GD3 molecules on native T and B cells and thymocytes by flow cytometry and (ii) activity and regulation of possible key enzymes for CD60a,b,c synthesis and degradation at the transcriptional level."}

{"project":"GlycoBiology-FMA","denotations":[{"id":"_T21","span":{"begin":44,"end":51},"obj":"FMAID:50594"},{"id":"_T22","span":{"begin":44,"end":51},"obj":"FMAID:146300"},{"id":"_T23","span":{"begin":120,"end":138},"obj":"FMAID:82818"},{"id":"_T24","span":{"begin":120,"end":138},"obj":"FMAID:82819"},{"id":"_T25","span":{"begin":120,"end":138},"obj":"FMAID:196815"},{"id":"_T26","span":{"begin":120,"end":138},"obj":"FMAID:196813"},{"id":"_T27","span":{"begin":120,"end":138},"obj":"FMAID:196807"},{"id":"_T28","span":{"begin":120,"end":138},"obj":"FMAID:82812"},{"id":"_T29","span":{"begin":120,"end":138},"obj":"FMAID:196814"},{"id":"_T30","span":{"begin":120,"end":138},"obj":"FMAID:82813"},{"id":"_T31","span":{"begin":120,"end":138},"obj":"FMAID:196810"},{"id":"_T32","span":{"begin":120,"end":138},"obj":"FMAID:82815"},{"id":"_T33","span":{"begin":120,"end":138},"obj":"FMAID:196806"},{"id":"_T34","span":{"begin":120,"end":138},"obj":"FMAID:196812"},{"id":"_T35","span":{"begin":120,"end":138},"obj":"FMAID:82817"},{"id":"_T36","span":{"begin":120,"end":138},"obj":"FMAID:196809"},{"id":"_T37","span":{"begin":120,"end":138},"obj":"FMAID:82814"},{"id":"_T38","span":{"begin":120,"end":138},"obj":"FMAID:82811"},{"id":"_T39","span":{"begin":120,"end":138},"obj":"FMAID:196808"},{"id":"_T40","span":{"begin":148,"end":159},"obj":"FMAID:167173"},{"id":"_T41","span":{"begin":148,"end":159},"obj":"FMAID:62863"},{"id":"_T42","span":{"begin":148,"end":159},"obj":"FMAID:167163"},{"id":"_T43","span":{"begin":148,"end":159},"obj":"FMAID:167171"},{"id":"_T44","span":{"begin":148,"end":159},"obj":"FMAID:62869"},{"id":"_T45","span":{"begin":148,"end":159},"obj":"FMAID:167174"},{"id":"_T46","span":{"begin":148,"end":159},"obj":"FMAID:62870"},{"id":"_T47","span":{"begin":148,"end":159},"obj":"FMAID:167176"},{"id":"_T48","span":{"begin":257,"end":262},"obj":"FMAID:68646"},{"id":"_T49","span":{"begin":257,"end":262},"obj":"FMAID:169002"},{"id":"_T50","span":{"begin":267,"end":277},"obj":"FMAID:72202"},{"id":"_T51","span":{"begin":267,"end":277},"obj":"FMAID:174276"}],"namespaces":[{"prefix":"FMAID","uri":"http://purl.org/sig/ont/fma/fma"}],"text":"In order to investigate the balance between surface and intracellular expression and synthesis and degradation of these glycosphingolipids in human lymphocytes of various differentiation stages, we analyzed (i) expression of GD3 molecules on native T and B cells and thymocytes by flow cytometry and (ii) activity and regulation of possible key enzymes for CD60a,b,c synthesis and degradation at the transcriptional level."}

{"project":"uniprot-human","denotations":[{"id":"T1","span":{"begin":301,"end":303},"obj":"http://www.uniprot.org/uniprot/Q8SNA0"}],"text":"In order to investigate the balance between surface and intracellular expression and synthesis and degradation of these glycosphingolipids in human lymphocytes of various differentiation stages, we analyzed (i) expression of GD3 molecules on native T and B cells and thymocytes by flow cytometry and (ii) activity and regulation of possible key enzymes for CD60a,b,c synthesis and degradation at the transcriptional level."}

{"project":"uniprot-mouse","denotations":[{"id":"T1","span":{"begin":301,"end":303},"obj":"http://www.uniprot.org/uniprot/P04441"}],"text":"In order to investigate the balance between surface and intracellular expression and synthesis and degradation of these glycosphingolipids in human lymphocytes of various differentiation stages, we analyzed (i) expression of GD3 molecules on native T and B cells and thymocytes by flow cytometry and (ii) activity and regulation of possible key enzymes for CD60a,b,c synthesis and degradation at the transcriptional level."}

{"project":"GlycoBiology-NCBITAXON","denotations":[{"id":"T2","span":{"begin":257,"end":262},"obj":"http://purl.bioontology.org/ontology/STY/T025"}],"text":"In order to investigate the balance between surface and intracellular expression and synthesis and degradation of these glycosphingolipids in human lymphocytes of various differentiation stages, we analyzed (i) expression of GD3 molecules on native T and B cells and thymocytes by flow cytometry and (ii) activity and regulation of possible key enzymes for CD60a,b,c synthesis and degradation at the transcriptional level."}

{"project":"GO-BP","denotations":[{"id":"T3","span":{"begin":318,"end":328},"obj":"http://purl.obolibrary.org/obo/GO_0065007"},{"id":"T14","span":{"begin":85,"end":94},"obj":"http://purl.obolibrary.org/obo/GO_0009058"},{"id":"T15","span":{"begin":367,"end":376},"obj":"http://purl.obolibrary.org/obo/GO_0009058"},{"id":"T17","span":{"begin":99,"end":110},"obj":"http://purl.obolibrary.org/obo/GO_0009056"},{"id":"T18","span":{"begin":381,"end":392},"obj":"http://purl.obolibrary.org/obo/GO_0009056"},{"id":"T19","span":{"begin":99,"end":138},"obj":"http://purl.obolibrary.org/obo/GO_0046479"},{"id":"T20","span":{"begin":301,"end":328},"obj":"http://purl.obolibrary.org/obo/GO_1904005"},{"id":"T21","span":{"begin":400,"end":415},"obj":"http://purl.obolibrary.org/obo/GO_0006351"}],"text":"In order to investigate the balance between surface and intracellular expression and synthesis and degradation of these glycosphingolipids in human lymphocytes of various differentiation stages, we analyzed (i) expression of GD3 molecules on native T and B cells and thymocytes by flow cytometry and (ii) activity and regulation of possible key enzymes for CD60a,b,c synthesis and degradation at the transcriptional level."}

{"project":"GO-CC","denotations":[{"id":"T2","span":{"begin":56,"end":69},"obj":"http://purl.obolibrary.org/obo/GO_0005622"},{"id":"T4","span":{"begin":257,"end":262},"obj":"http://purl.obolibrary.org/obo/GO_0005623"}],"text":"In order to investigate the balance between surface and intracellular expression and synthesis and degradation of these glycosphingolipids in human lymphocytes of various differentiation stages, we analyzed (i) expression of GD3 molecules on native T and B cells and thymocytes by flow cytometry and (ii) activity and regulation of possible key enzymes for CD60a,b,c synthesis and degradation at the transcriptional level."}

{"project":"Glycan-GlyCosmos","denotations":[{"id":"T5","span":{"begin":225,"end":228},"obj":"Glycan"}],"attributes":[{"id":"A5","pred":"glycosmos_id","subj":"T5","obj":"https://glycosmos.org/glycans/show/G98544DH"},{"id":"A15","pred":"image","subj":"T5","obj":"https://api.glycosmos.org/wurcs2image/latest/png/binary/G98544DH"}],"text":"In order to investigate the balance between surface and intracellular expression and synthesis and degradation of these glycosphingolipids in human lymphocytes of various differentiation stages, we analyzed (i) expression of GD3 molecules on native T and B cells and thymocytes by flow cytometry and (ii) activity and regulation of possible key enzymes for CD60a,b,c synthesis and degradation at the transcriptional level."}

{"project":"GlyCosmos15-NCBITAXON","denotations":[{"id":"T2","span":{"begin":142,"end":147},"obj":"OrganismTaxon"}],"attributes":[{"id":"A2","pred":"db_id","subj":"T2","obj":"9606"}],"text":"In order to investigate the balance between surface and intracellular expression and synthesis and degradation of these glycosphingolipids in human lymphocytes of various differentiation stages, we analyzed (i) expression of GD3 molecules on native T and B cells and thymocytes by flow cytometry and (ii) activity and regulation of possible key enzymes for CD60a,b,c synthesis and degradation at the transcriptional level."}

{"project":"GlyCosmos15-CL","denotations":[{"id":"T4","span":{"begin":148,"end":159},"obj":"Cell"},{"id":"T5","span":{"begin":255,"end":262},"obj":"Cell"},{"id":"T6","span":{"begin":267,"end":277},"obj":"Cell"}],"attributes":[{"id":"A4","pred":"cl_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/CL:0000542"},{"id":"A5","pred":"cl_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/CL:0000236"},{"id":"A6","pred":"cl_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/CL:0000893"}],"text":"In order to investigate the balance between surface and intracellular expression and synthesis and degradation of these glycosphingolipids in human lymphocytes of various differentiation stages, we analyzed (i) expression of GD3 molecules on native T and B cells and thymocytes by flow cytometry and (ii) activity and regulation of possible key enzymes for CD60a,b,c synthesis and degradation at the transcriptional level."}

{"project":"GlyCosmos15-UBERON","denotations":[{"id":"T4","span":{"begin":56,"end":69},"obj":"Body_part"},{"id":"T5","span":{"begin":148,"end":159},"obj":"Body_part"},{"id":"T6","span":{"begin":267,"end":277},"obj":"Body_part"}],"attributes":[{"id":"A4","pred":"uberon_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/GO_0005622"},{"id":"A5","pred":"uberon_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/CL_0000542"},{"id":"A6","pred":"uberon_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/CL_0000893"}],"text":"In order to investigate the balance between surface and intracellular expression and synthesis and degradation of these glycosphingolipids in human lymphocytes of various differentiation stages, we analyzed (i) expression of GD3 molecules on native T and B cells and thymocytes by flow cytometry and (ii) activity and regulation of possible key enzymes for CD60a,b,c synthesis and degradation at the transcriptional level."}

{"project":"sentences","denotations":[{"id":"TextSentencer_T4","span":{"begin":0,"end":422},"obj":"Sentence"},{"id":"T4","span":{"begin":0,"end":422},"obj":"Sentence"},{"id":"T4","span":{"begin":0,"end":422},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"In order to investigate the balance between surface and intracellular expression and synthesis and degradation of these glycosphingolipids in human lymphocytes of various differentiation stages, we analyzed (i) expression of GD3 molecules on native T and B cells and thymocytes by flow cytometry and (ii) activity and regulation of possible key enzymes for CD60a,b,c synthesis and degradation at the transcriptional level."}

{"project":"GlyCosmos15-Sentences","blocks":[{"id":"T4","span":{"begin":0,"end":422},"obj":"Sentence"}],"text":"In order to investigate the balance between surface and intracellular expression and synthesis and degradation of these glycosphingolipids in human lymphocytes of various differentiation stages, we analyzed (i) expression of GD3 molecules on native T and B cells and thymocytes by flow cytometry and (ii) activity and regulation of possible key enzymes for CD60a,b,c synthesis and degradation at the transcriptional level."}

{"project":"GlyCosmos15-Glycan","denotations":[{"id":"T5","span":{"begin":225,"end":228},"obj":"Glycan"}],"attributes":[{"id":"A5","pred":"glycosmos_id","subj":"T5","obj":"https://glycosmos.org/glycans/show/G98544DH"},{"id":"A15","pred":"image","subj":"T5","obj":"https://api.glycosmos.org/wurcs2image/latest/png/binary/G98544DH"}],"text":"In order to investigate the balance between surface and intracellular expression and synthesis and degradation of these glycosphingolipids in human lymphocytes of various differentiation stages, we analyzed (i) expression of GD3 molecules on native T and B cells and thymocytes by flow cytometry and (ii) activity and regulation of possible key enzymes for CD60a,b,c synthesis and degradation at the transcriptional level."}

{"project":"NCBITAXON","denotations":[{"id":"T2","span":{"begin":142,"end":147},"obj":"OrganismTaxon"}],"attributes":[{"id":"A2","pred":"db_id","subj":"T2","obj":"9606"}],"text":"In order to investigate the balance between surface and intracellular expression and synthesis and degradation of these glycosphingolipids in human lymphocytes of various differentiation stages, we analyzed (i) expression of GD3 molecules on native T and B cells and thymocytes by flow cytometry and (ii) activity and regulation of possible key enzymes for CD60a,b,c synthesis and degradation at the transcriptional level."}

{"project":"Anatomy-UBERON","denotations":[{"id":"T4","span":{"begin":56,"end":69},"obj":"Body_part"},{"id":"T5","span":{"begin":148,"end":159},"obj":"Body_part"},{"id":"T6","span":{"begin":267,"end":277},"obj":"Body_part"}],"attributes":[{"id":"A4","pred":"uberon_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/GO_0005622"},{"id":"A5","pred":"uberon_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/CL_0000542"},{"id":"A6","pred":"uberon_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/CL_0000893"}],"text":"In order to investigate the balance between surface and intracellular expression and synthesis and degradation of these glycosphingolipids in human lymphocytes of various differentiation stages, we analyzed (i) expression of GD3 molecules on native T and B cells and thymocytes by flow cytometry and (ii) activity and regulation of possible key enzymes for CD60a,b,c synthesis and degradation at the transcriptional level."}

{"project":"CL-cell","denotations":[{"id":"T4","span":{"begin":148,"end":159},"obj":"Cell"},{"id":"T5","span":{"begin":255,"end":262},"obj":"Cell"},{"id":"T6","span":{"begin":267,"end":277},"obj":"Cell"}],"attributes":[{"id":"A4","pred":"cl_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/CL:0000542"},{"id":"A5","pred":"cl_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/CL:0000236"},{"id":"A6","pred":"cl_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/CL:0000893"}],"text":"In order to investigate the balance between surface and intracellular expression and synthesis and degradation of these glycosphingolipids in human lymphocytes of various differentiation stages, we analyzed (i) expression of GD3 molecules on native T and B cells and thymocytes by flow cytometry and (ii) activity and regulation of possible key enzymes for CD60a,b,c synthesis and degradation at the transcriptional level."}