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PubMed:2142528 JSONTXT

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jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 22-54 protein denotes active transcription factor CREB
T2 56-93 protein denotes cAMP response element binding protein
T3 96-111 cell_type denotes Mammalian cells
T4 142-167 protein denotes transcription factor CREB
T5 169-206 protein denotes cAMP response element binding protein
T6 272-292 RNA denotes CREB gene transcript
T7 323-358 protein denotes 14-amino acid serine-rich insertion
T8 381-394 protein denotes CREB isoforms
T9 414-427 protein denotes CREB isoforms
T10 445-460 cell_type denotes many cell types
T11 533-563 DNA denotes cAMP response element in vitro
T12 609-622 protein denotes CREB proteins
T13 709-740 DNA denotes heterologous DNA-binding domain
T14 823-827 protein denotes CREB
T15 854-867 protein denotes CREB isoforms
T16 941-958 protein denotes regulatory domain
T17 987-1000 protein denotes CREB proteins

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-95 Sentence denotes Two distinct forms of active transcription factor CREB (cAMP response element binding protein).
S2 96-293 Sentence denotes Mammalian cells express two distinct forms of transcription factor CREB (cAMP response element binding protein) that are apparently the products of alternative splicing of the CREB gene transcript.
S3 294-395 Sentence denotes The two proteins differ by a 14-amino acid serine-rich insertion present in one of the CREB isoforms.
S4 396-483 Sentence denotes We show that both CREB isoforms are expressed in many cell types and mammalian species.
S5 484-564 Sentence denotes Both encode proteins that bind specifically to a cAMP response element in vitro.
S6 565-642 Sentence denotes As expected for proteins of this class, the CREB proteins bind DNA as dimers.
S7 643-828 Sentence denotes Both proteins impart cAMP-regulated transcriptional activity to a heterologous DNA-binding domain, showing that cAMP directly modulates the transcriptional stimulatory activity of CREB.
S8 829-1089 Sentence denotes The presence of multiple CREB isoforms with identical DNA-binding specificities but differences in the presumed regulatory domain raises the possibility that CREB proteins may be able to integrate distinct regulatory signals at the level of gene transcription.

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 0-94 NP denotes Two distinct forms of active transcription factor CREB (cAMP response element binding protein)
C3 120-207 NP denotes two distinct forms of transcription factor CREB (cAMP response element binding protein)
C4 208-212 NP denotes that
C2 120-292 NP denotes two distinct forms of transcription factor CREB (cAMP response element binding protein) that are apparently the products of alternative splicing of the CREB gene transcript
C5 294-310 NP denotes The two proteins
C6 377-394 NP denotes the CREB isoforms
C7 409-427 NP denotes both CREB isoforms
C8 484-488 NP denotes Both
C9 496-504 NP denotes proteins
C10 505-509 NP denotes that
C11 605-622 NP denotes the CREB proteins
C12 643-656 NP denotes Both proteins
C13 823-827 NP denotes CREB
C14 966-981 NP denotes the possibility
C15 982-986 NP denotes that
C16 987-1000 NP denotes CREB proteins
R1 C4 C3 coref-relat that,two distinct forms of transcription factor CREB (cAMP response element binding protein)
R2 C2 C1 coref-ident two distinct forms of transcription factor CREB (cAMP response element binding protein) that are apparently the products of alternative splicing of the CREB gene transcript,Two distinct forms of active transcription factor CREB (cAMP response element binding protein)
R3 C5 C2 coref-ident The two proteins,two distinct forms of transcription factor CREB (cAMP response element binding protein) that are apparently the products of alternative splicing of the CREB gene transcript
R4 C6 C5 coref-ident the CREB isoforms,The two proteins
R5 C7 C6 coref-ident both CREB isoforms,the CREB isoforms
R6 C8 C7 coref-pron Both,both CREB isoforms
R7 C10 C9 coref-relat that,proteins
R8 C11 C5 coref-ident the CREB proteins,The two proteins
R9 C12 C5 coref-ident Both proteins,The two proteins
R10 C13 C2 coref-ident CREB,two distinct forms of transcription factor CREB (cAMP response element binding protein) that are apparently the products of alternative splicing of the CREB gene transcript
R11 C15 C14 coref-relat that,the possibility
R12 C16 C11 coref-ident CREB proteins,the CREB proteins

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 22-54 protein_molecule denotes active transcription factor CREB
T2 56-60 nucleotide denotes cAMP
T3 96-111 cell_type denotes Mammalian cells
T4 142-162 protein_molecule denotes transcription factor
T5 163-167 protein_molecule denotes CREB
T6 169-173 nucleotide denotes cAMP
T7 244-264 other_name denotes alternative splicing
T8 272-276 protein_molecule denotes CREB
T9 323-358 protein_domain_or_region denotes 14-amino acid serine-rich insertion
T10 381-385 protein_molecule denotes CREB
T11 414-418 protein_molecule denotes CREB
T12 445-460 cell_type denotes many cell types
T13 465-482 multi_cell denotes mammalian species
T14 533-537 nucleotide denotes cAMP
T15 609-613 protein_molecule denotes CREB
T16 664-668 nucleotide denotes cAMP
T17 709-740 DNA_domain_or_region denotes heterologous DNA-binding domain
T18 755-759 nucleotide denotes cAMP
T19 783-819 other_name denotes transcriptional stimulatory activity
T20 823-827 protein_molecule denotes CREB
T21 854-858 protein_molecule denotes CREB
T22 883-908 other_name denotes DNA-binding specificities
T23 941-958 protein_domain_or_region denotes regulatory domain
T24 987-991 protein_molecule denotes CREB
T25 1070-1088 other_name denotes gene transcription