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PubMed:2136386 JSONTXT

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Glycan-Motif

Id Subject Object Predicate Lexical cue
T1 20-35 https://glytoucan.org/Structures/Glycans/G00065MO denotes polysialic acid
T2 89-100 https://glytoucan.org/Structures/Glycans/G81533KY denotes sialic acid
T3 295-310 https://glytoucan.org/Structures/Glycans/G00065MO denotes polysialic acid
T4 312-319 https://glytoucan.org/Structures/Glycans/G00065MO denotes polySia
T5 883-890 https://glytoucan.org/Structures/Glycans/G00065MO denotes polySia

GlyCosmos6-Glycan-Motif-Image

Id Subject Object Predicate Lexical cue image
T1 20-35 Glycan_Motif denotes polysialic acid https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00065MO
T2 89-100 Glycan_Motif denotes sialic acid https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81533KY
T3 295-310 Glycan_Motif denotes polysialic acid https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00065MO
T4 312-319 Glycan_Motif denotes polySia https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00065MO
T5 883-890 Glycan_Motif denotes polySia https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00065MO

GlyCosmos6-Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 20-35 https://glytoucan.org/Structures/Glycans/G00065MO denotes polysialic acid
T2 89-100 https://glytoucan.org/Structures/Glycans/G81533KY denotes sialic acid
T3 295-310 https://glytoucan.org/Structures/Glycans/G00065MO denotes polysialic acid

GlycoBiology-PACDB

Id Subject Object Predicate Lexical cue
_T1 47-63 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC002,LEC056,LEC062,LEC069,LEC081,LEC111,LEC133,LEC171,LEC177,LEC187,LEC211,LEC242,LEC252,LEC258,LEC259,LEC260,LEC262,LEC369,LEC377,LEC422,LEC442,LEC448,LEC450,LEC451,LEC454,LEC472,LEC492,LEC620 denotes Escherichia coli
_T2 47-63 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC243,LEC640 denotes Escherichia coli
_T3 47-63 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC157,LEC407 denotes Escherichia coli
_T4 47-63 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC054,LEC058,LEC073,LEC082,LEC091,LEC103,LEC109,LEC110,LEC123,LEC158,LEC179,LEC198,LEC205,LEC222,LEC223,LEC224,LEC225,LEC232,LEC298,LEC357,LEC378,LEC383,LEC388,LEC389,LEC397,LEC401,LEC410,LEC452 denotes Escherichia coli
_T5 47-63 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC244,LEC256,LEC354 denotes Escherichia coli
_T6 47-63 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC754 denotes Escherichia coli
_T7 47-66 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC247,LEC554 denotes Escherichia coli K1
_T8 47-66 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC263,LEC665 denotes Escherichia coli K1
_T9 47-66 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC636 denotes Escherichia coli K1
_T10 47-66 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC324 denotes Escherichia coli K1
_T11 47-66 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC295,LEC417 denotes Escherichia coli K1
_T12 47-66 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC487 denotes Escherichia coli K1
_T13 178-194 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC243,LEC640 denotes Escherichia coli
_T14 178-194 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC002,LEC056,LEC062,LEC069,LEC081,LEC111,LEC133,LEC171,LEC177,LEC187,LEC211,LEC242,LEC252,LEC258,LEC259,LEC260,LEC262,LEC369,LEC377,LEC422,LEC442,LEC448,LEC450,LEC451,LEC454,LEC472,LEC492,LEC620 denotes Escherichia coli
_T15 178-194 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC054,LEC058,LEC073,LEC082,LEC091,LEC103,LEC109,LEC110,LEC123,LEC158,LEC179,LEC198,LEC205,LEC222,LEC223,LEC224,LEC225,LEC232,LEC298,LEC357,LEC378,LEC383,LEC388,LEC389,LEC397,LEC401,LEC410,LEC452 denotes Escherichia coli
_T16 178-194 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC157,LEC407 denotes Escherichia coli
_T17 178-194 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC754 denotes Escherichia coli
_T18 178-194 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC244,LEC256,LEC354 denotes Escherichia coli
_T19 178-197 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC263,LEC665 denotes Escherichia coli K1
_T20 178-197 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC247,LEC554 denotes Escherichia coli K1
_T21 178-197 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC324 denotes Escherichia coli K1
_T22 178-197 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC295,LEC417 denotes Escherichia coli K1
_T23 178-197 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC487 denotes Escherichia coli K1
_T24 178-197 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC636 denotes Escherichia coli K1

GlycoBiology-FMA

Id Subject Object Predicate Lexical cue
_T1 36-43 FMAID:85272 denotes capsule
_T2 36-43 FMAID:199625 denotes capsule
_T3 36-46 FMAID:218590 denotes capsule in
_T4 120-127 FMAID:85272 denotes capsule
_T5 120-127 FMAID:199625 denotes capsule
_T6 198-203 FMAID:169002 denotes cells
_T7 198-203 FMAID:68646 denotes cells
_T8 321-328 FMAID:85272 denotes capsule
_T9 321-328 FMAID:199625 denotes capsule
_T10 419-426 FMAID:85272 denotes capsule
_T11 419-426 FMAID:199625 denotes capsule
_T12 891-898 FMAID:85272 denotes capsule
_T13 891-898 FMAID:199625 denotes capsule
_T14 1044-1054 FMAID:166112 denotes mg protein
_T15 1047-1054 FMAID:67257 denotes protein
_T16 1047-1054 FMAID:165447 denotes protein
_T17 1330-1337 FMAID:67257 denotes protein
_T18 1330-1337 FMAID:165447 denotes protein
_T19 1460-1467 FMAID:84785 denotes in cell
_T20 1460-1467 FMAID:199054 denotes in cell
_T21 1518-1523 FMAID:169002 denotes cells
_T22 1518-1523 FMAID:68646 denotes cells

uniprot-human

Id Subject Object Predicate Lexical cue
T1 64-66 http://www.uniprot.org/uniprot/P04264 denotes K1
T2 195-197 http://www.uniprot.org/uniprot/P04264 denotes K1
T3 511-513 http://www.uniprot.org/uniprot/P04264 denotes K1
T4 89-109 http://www.uniprot.org/uniprot/Q9NR45 denotes sialic acid synthase
T5 702-705 http://www.uniprot.org/uniprot/P21941 denotes CMP
T6 754-757 http://www.uniprot.org/uniprot/P21941 denotes CMP
T7 866-869 http://www.uniprot.org/uniprot/P21941 denotes CMP

uniprot-mouse

Id Subject Object Predicate Lexical cue
T1 64-66 http://www.uniprot.org/uniprot/P04104 denotes K1
T2 195-197 http://www.uniprot.org/uniprot/P04104 denotes K1
T3 511-513 http://www.uniprot.org/uniprot/P04104 denotes K1
T4 1228-1230 http://www.uniprot.org/uniprot/Q9DCA7 denotes ca
T5 1628-1630 http://www.uniprot.org/uniprot/Q8VHK8 denotes AT

GlycoBiology-NCBITAXON

Id Subject Object Predicate Lexical cue
T1 47-58 http://purl.bioontology.org/ontology/NCBITAXON/561 denotes Escherichia
T2 178-189 http://purl.bioontology.org/ontology/NCBITAXON/561 denotes Escherichia
T3 198-203 http://purl.bioontology.org/ontology/STY/T025 denotes cells
T4 576-579 http://purl.bioontology.org/ontology/NCBITAXON/208766 denotes Sia
T5 576-579 http://purl.bioontology.org/ontology/NCBITAXON/172412 denotes Sia
T6 606-609 http://purl.bioontology.org/ontology/NCBITAXON/208766 denotes Sia
T7 606-609 http://purl.bioontology.org/ontology/NCBITAXON/172412 denotes Sia
T8 637-640 http://purl.bioontology.org/ontology/NCBITAXON/208766 denotes Sia
T9 637-640 http://purl.bioontology.org/ontology/NCBITAXON/172412 denotes Sia
T10 694-697 http://purl.bioontology.org/ontology/NCBITAXON/208766 denotes Sia
T11 694-697 http://purl.bioontology.org/ontology/NCBITAXON/172412 denotes Sia
T12 706-709 http://purl.bioontology.org/ontology/NCBITAXON/172412 denotes Sia
T13 706-709 http://purl.bioontology.org/ontology/NCBITAXON/208766 denotes Sia
T14 758-761 http://purl.bioontology.org/ontology/NCBITAXON/172412 denotes Sia
T15 758-761 http://purl.bioontology.org/ontology/NCBITAXON/208766 denotes Sia
T16 801-804 http://purl.bioontology.org/ontology/NCBITAXON/208766 denotes Sia
T17 801-804 http://purl.bioontology.org/ontology/NCBITAXON/172412 denotes Sia
T18 861-864 http://purl.bioontology.org/ontology/NCBITAXON/172412 denotes Sia
T19 861-864 http://purl.bioontology.org/ontology/NCBITAXON/208766 denotes Sia
T20 870-873 http://purl.bioontology.org/ontology/NCBITAXON/208766 denotes Sia
T21 870-873 http://purl.bioontology.org/ontology/NCBITAXON/172412 denotes Sia
T22 997-1000 http://purl.bioontology.org/ontology/NCBITAXON/208766 denotes Sia
T23 997-1000 http://purl.bioontology.org/ontology/NCBITAXON/172412 denotes Sia
T24 1087-1090 http://purl.bioontology.org/ontology/NCBITAXON/208766 denotes Sia
T25 1087-1090 http://purl.bioontology.org/ontology/NCBITAXON/172412 denotes Sia
T26 1214-1217 http://purl.bioontology.org/ontology/NCBITAXON/208766 denotes Sia
T27 1214-1217 http://purl.bioontology.org/ontology/NCBITAXON/172412 denotes Sia
T28 1399-1402 http://purl.bioontology.org/ontology/NCBITAXON/172412 denotes Sia
T29 1399-1402 http://purl.bioontology.org/ontology/NCBITAXON/208766 denotes Sia
T30 1424-1427 http://purl.bioontology.org/ontology/NCBITAXON/208766 denotes Sia
T31 1424-1427 http://purl.bioontology.org/ontology/NCBITAXON/172412 denotes Sia
T32 1518-1523 http://purl.bioontology.org/ontology/STY/T025 denotes cells

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-67 Sentence denotes Biosynthesis of the polysialic acid capsule in Escherichia coli K1.
TextSentencer_T2 68-158 Sentence denotes Cold inactivation of sialic acid synthase regulates capsule expression below 20 degrees C.
TextSentencer_T3 159-329 Sentence denotes When neuroinvasive Escherichia coli K1 cells are grown at temperatures below 20 degrees C, they fail to synthesize the alpha-2,8-linked polysialic acid (polySia) capsule.
TextSentencer_T4 330-473 Sentence denotes The objective of this study was to use a genetic and biochemical approach to analyse why capsule expression was defective at cold temperatures.
TextSentencer_T5 474-580 Sentence denotes The strategy was to construct E.coli K1-derived mutants with defects in activation and degradation of Sia.
TextSentencer_T6 581-710 Sentence denotes The inability to degrade Sia because of a defect in the Sia-specific aldolase permitted accurate quantitation of Sia and CMP-Sia.
TextSentencer_T7 711-805 Sentence denotes Strains EV5 and EV90 possessed a defective CMP-Sia synthetase and were unable to activate Sia.
TextSentencer_T8 806-938 Sentence denotes These mutants were then used to study how synthesis of Sia, CMP-Sia, and the polySia capsule was affected by growth at 15 degrees C.
TextSentencer_T9 939-1074 Sentence denotes In contrast to wild type strains, the mutants accumulated Sia in considerable quantities (up to 100 nmol mg protein-1) at 37 degrees C.
TextSentencer_T10 1075-1133 Sentence denotes However, no Sia was detected after growth at 15 degrees C.
TextSentencer_T11 1134-1231 Sentence denotes A temperature upshift experiment showed that the intracellular concentration of Sia increased ca.
TextSentencer_T12 1232-1376 Sentence denotes 3-fold within 5-10 min after shift from 15 to 37 degrees C, even in the presence of inhibitors of protein synthesis or transcription initiation.
TextSentencer_T13 1377-1641 Sentence denotes An in vitro assay for Sia synthase showed that Sia was synthesized at 37 degrees C in cell-free extracts from both 37 and 15 degrees C grown cells, but that no synthesis occurred when the same extracts were assayed at 15 degrees C.(ABSTRACT TRUNCATED AT 250 WORDS)
T1 0-67 Sentence denotes Biosynthesis of the polysialic acid capsule in Escherichia coli K1.
T2 68-158 Sentence denotes Cold inactivation of sialic acid synthase regulates capsule expression below 20 degrees C.
T3 159-329 Sentence denotes When neuroinvasive Escherichia coli K1 cells are grown at temperatures below 20 degrees C, they fail to synthesize the alpha-2,8-linked polysialic acid (polySia) capsule.
T4 330-473 Sentence denotes The objective of this study was to use a genetic and biochemical approach to analyse why capsule expression was defective at cold temperatures.
T5 474-1231 Sentence denotes The strategy was to construct E.coli K1-derived mutants with defects in activation and degradation of Sia. The inability to degrade Sia because of a defect in the Sia-specific aldolase permitted accurate quantitation of Sia and CMP-Sia. Strains EV5 and EV90 possessed a defective CMP-Sia synthetase and were unable to activate Sia. These mutants were then used to study how synthesis of Sia, CMP-Sia, and the polySia capsule was affected by growth at 15 degrees C. In contrast to wild type strains, the mutants accumulated Sia in considerable quantities (up to 100 nmol mg protein-1) at 37 degrees C. However, no Sia was detected after growth at 15 degrees C. A temperature upshift experiment showed that the intracellular concentration of Sia increased ca.
T6 1232-1376 Sentence denotes 3-fold within 5-10 min after shift from 15 to 37 degrees C, even in the presence of inhibitors of protein synthesis or transcription initiation.
T7 1377-1641 Sentence denotes An in vitro assay for Sia synthase showed that Sia was synthesized at 37 degrees C in cell-free extracts from both 37 and 15 degrees C grown cells, but that no synthesis occurred when the same extracts were assayed at 15 degrees C.(ABSTRACT TRUNCATED AT 250 WORDS)
T1 0-67 Sentence denotes Biosynthesis of the polysialic acid capsule in Escherichia coli K1.
T2 68-158 Sentence denotes Cold inactivation of sialic acid synthase regulates capsule expression below 20 degrees C.
T3 159-329 Sentence denotes When neuroinvasive Escherichia coli K1 cells are grown at temperatures below 20 degrees C, they fail to synthesize the alpha-2,8-linked polysialic acid (polySia) capsule.
T4 330-473 Sentence denotes The objective of this study was to use a genetic and biochemical approach to analyse why capsule expression was defective at cold temperatures.
T5 474-580 Sentence denotes The strategy was to construct E.coli K1-derived mutants with defects in activation and degradation of Sia.
T6 581-710 Sentence denotes The inability to degrade Sia because of a defect in the Sia-specific aldolase permitted accurate quantitation of Sia and CMP-Sia.
T7 711-805 Sentence denotes Strains EV5 and EV90 possessed a defective CMP-Sia synthetase and were unable to activate Sia.
T8 806-938 Sentence denotes These mutants were then used to study how synthesis of Sia, CMP-Sia, and the polySia capsule was affected by growth at 15 degrees C.
T9 939-1074 Sentence denotes In contrast to wild type strains, the mutants accumulated Sia in considerable quantities (up to 100 nmol mg protein-1) at 37 degrees C.
T10 1075-1133 Sentence denotes However, no Sia was detected after growth at 15 degrees C.
T11 1134-1231 Sentence denotes A temperature upshift experiment showed that the intracellular concentration of Sia increased ca.
T12 1232-1376 Sentence denotes 3-fold within 5-10 min after shift from 15 to 37 degrees C, even in the presence of inhibitors of protein synthesis or transcription initiation.
T13 1377-1641 Sentence denotes An in vitro assay for Sia synthase showed that Sia was synthesized at 37 degrees C in cell-free extracts from both 37 and 15 degrees C grown cells, but that no synthesis occurred when the same extracts were assayed at 15 degrees C.(ABSTRACT TRUNCATED AT 250 WORDS)

GO-BP

Id Subject Object Predicate Lexical cue
T1 0-12 http://purl.obolibrary.org/obo/GO_0009058 denotes Biosynthesis
T2 110-119 http://purl.obolibrary.org/obo/GO_0065007 denotes regulates
T3 561-572 http://purl.obolibrary.org/obo/GO_0009056 denotes degradation
T4 598-605 http://purl.obolibrary.org/obo/GO_0009056 denotes degrade
T5 848-857 http://purl.obolibrary.org/obo/GO_0009058 denotes synthesis
T6 1338-1347 http://purl.obolibrary.org/obo/GO_0009058 denotes synthesis
T7 1537-1546 http://purl.obolibrary.org/obo/GO_0009058 denotes synthesis
T8 915-921 http://purl.obolibrary.org/obo/GO_0040007 denotes growth
T9 1110-1116 http://purl.obolibrary.org/obo/GO_0040007 denotes growth
T10 1228-1230 http://purl.obolibrary.org/obo/GO_0033968 denotes ca
T11 1330-1347 http://purl.obolibrary.org/obo/GO_0006412 denotes protein synthesis
T12 1351-1364 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription

GO-CC

Id Subject Object Predicate Lexical cue
T1 198-203 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T2 1463-1467 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T3 1183-1196 http://purl.obolibrary.org/obo/GO_0005622 denotes intracellular

UBERON-AE

Id Subject Object Predicate Lexical cue
T1 36-43 http://purl.obolibrary.org/obo/UBERON_0003893 denotes capsule
T2 120-127 http://purl.obolibrary.org/obo/UBERON_0003893 denotes capsule
T3 321-328 http://purl.obolibrary.org/obo/UBERON_0003893 denotes capsule
T4 419-426 http://purl.obolibrary.org/obo/UBERON_0003893 denotes capsule
T5 891-898 http://purl.obolibrary.org/obo/UBERON_0003893 denotes capsule

Lectin

Id Subject Object Predicate Lexical cue
Lectin_T1 1228-1230 https://acgg.asia/db/lfdb/LfDB0227 denotes ca

performance-test

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 36-43 http://purl.obolibrary.org/obo/UBERON_0003893 denotes capsule
PD-UBERON-AE-B_T2 120-127 http://purl.obolibrary.org/obo/UBERON_0003893 denotes capsule
PD-UBERON-AE-B_T3 321-328 http://purl.obolibrary.org/obo/UBERON_0003893 denotes capsule
PD-UBERON-AE-B_T4 419-426 http://purl.obolibrary.org/obo/UBERON_0003893 denotes capsule
PD-UBERON-AE-B_T5 891-898 http://purl.obolibrary.org/obo/UBERON_0003893 denotes capsule

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 47-63 OrganismTaxon denotes Escherichia coli 562
T2 178-194 OrganismTaxon denotes Escherichia coli 562

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 1183-1196 Body_part denotes intracellular http://purl.obolibrary.org/obo/GO_0005622

CL-cell

Id Subject Object Predicate Lexical cue cl_id
T1 1458-1467 Cell denotes C in cell http://purl.obolibrary.org/obo/CL:0000570