PubMed:21329384
Annnotations
Glycosmos6-MAT
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 116-124 | http://purl.obolibrary.org/obo/MAT_0000279 | denotes | placenta |
DisGeNET
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T0 | 358-367 | gene:6277 | denotes | calcyclin |
| T1 | 338-347 | disease:C0013537 | denotes | eclampsia |
| T2 | 369-375 | gene:6277 | denotes | S100A6 |
| T3 | 338-347 | disease:C0013537 | denotes | eclampsia |
| R1 | T0 | T1 | associated_with | calcyclin,eclampsia |
| R2 | T2 | T3 | associated_with | S100A6,eclampsia |
Allie
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| SS1_21329384_3_0 | 573-601 | expanded | denotes | multiple reaction monitoring |
| SS2_21329384_3_0 | 603-606 | abbr | denotes | MRM |
| SS1_21329384_4_0 | 779-811 | expanded | denotes | formalin-fixed paraffin-embedded |
| SS2_21329384_4_0 | 813-817 | abbr | denotes | FFPE |
| AE1_21329384_3_0 | SS1_21329384_3_0 | SS2_21329384_3_0 | abbreviatedTo | multiple reaction monitoring,MRM |
| AE1_21329384_4_0 | SS1_21329384_4_0 | SS2_21329384_4_0 | abbreviatedTo | formalin-fixed paraffin-embedded,FFPE |
PubmedHPO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 148-161 | HP_0100602 | denotes | pre-eclampsia |
| T2 | 152-161 | HP_0100601 | denotes | eclampsia |
| T3 | 334-347 | HP_0100602 | denotes | pre-eclampsia |
| T4 | 338-347 | HP_0100601 | denotes | eclampsia |
DisGeNET5_gene_disease
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 21329384-0#61#70#gene6277 | 61-70 | gene6277 | denotes | calcyclin |
| 21329384-0#43#52#diseaseC0013537 | 43-52 | diseaseC0013537 | denotes | eclampsia |
| 61#70#gene627743#52#diseaseC0013537 | 21329384-0#61#70#gene6277 | 21329384-0#43#52#diseaseC0013537 | associated_with | calcyclin,eclampsia |
Preeclampsia
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| PD-Preeclampsia-B_T1 | 39-52 | ORPHA:275555 | denotes | pre-eclampsia |
| PD-Preeclampsia-B_T2 | 148-161 | ORPHA:275555 | denotes | pre-eclampsia |
| PD-Preeclampsia-B_T3 | 334-347 | ORPHA:275555 | denotes | pre-eclampsia |
| PD-Preeclampsia-B_T4 | 1323-1345 | ORPHA:275555 | denotes | pre-eclamptic patients |
Preeclampsia-compare
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| PD-Preeclampsia-B_T1 | 39-52 | ORPHA:275555 | denotes | pre-eclampsia |
| PD-Preeclampsia-B_T2 | 148-161 | ORPHA:275555 | denotes | pre-eclampsia |
| PD-Preeclampsia-B_T3 | 334-347 | ORPHA:275555 | denotes | pre-eclampsia |
| PD-Preeclampsia-B_T4 | 692-705 | ORPHA:275555 | denotes | pre-eclamptic |
| PD-Preeclampsia-B_T5 | 1323-1336 | ORPHA:275555 | denotes | pre-eclamptic |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| TextSentencer_T1 | 0-125 | Sentence | denotes | Multiple reaction monitoring assay for pre-eclampsia related calcyclin peptides in formalin fixed paraffin embedded placenta. |
| TextSentencer_T2 | 126-286 | Sentence | denotes | Although the cause of pre-eclampsia during pregnancy has not been elucidated yet, it is evident that placental and maternal endothelial dysfunction is involved. |
| TextSentencer_T3 | 287-448 | Sentence | denotes | We previously demonstrated that in early onset pre-eclampsia placental calcyclin (S100A6) expression is significantly higher compared to controls ( De Groot , C. |
| TextSentencer_T4 | 449-459 | Sentence | denotes | J. ; Clin. |
| TextSentencer_T5 | 460-488 | Sentence | denotes | Proteomics 2007 , 1 , 325 ). |
| TextSentencer_T6 | 489-646 | Sentence | denotes | In the current study, the results were confirmed and relatively quantified by using multiple reaction monitoring (MRM) on two peptide fragments of calcyclin. |
| TextSentencer_T7 | 647-881 | Sentence | denotes | Cells were obtained from control (n = 5) and pre-eclamptic placental (n = 5) tissue collected by laser capture microdissection from formalin-fixed paraffin-embedded (FFPE) material treated with a solution to reverse formalin fixation. |
| TextSentencer_T8 | 882-1028 | Sentence | denotes | Two calcyclin peptides with an extra glycine inserted in the middle of the amino acid sequence were synthesized and used as an internal reference. |
| TextSentencer_T9 | 1029-1129 | Sentence | denotes | Data presented show that MRM on laser microdissected material from FFPE tissue material is possible. |
| TextSentencer_T10 | 1130-1455 | Sentence | denotes | The developed MRM assay to study quantitative levels of proteins in FFPE laser microdissected cells using nonisotopic-labeled chemical analogs of mass tagged internal references showed that in pre-eclamptic patients elevated levels of calcyclin is observed in placental trophoblast cells compared to normal trophoblast cells. |
| TextSentencer_T11 | 1456-1546 | Sentence | denotes | By immunohistochemistry, we were able to confirm this observation in a qualitative manner. |
| T1 | 0-125 | Sentence | denotes | Multiple reaction monitoring assay for pre-eclampsia related calcyclin peptides in formalin fixed paraffin embedded placenta. |
| T2 | 126-286 | Sentence | denotes | Although the cause of pre-eclampsia during pregnancy has not been elucidated yet, it is evident that placental and maternal endothelial dysfunction is involved. |
| T3 | 287-448 | Sentence | denotes | We previously demonstrated that in early onset pre-eclampsia placental calcyclin (S100A6) expression is significantly higher compared to controls ( De Groot , C. |
| T4 | 449-459 | Sentence | denotes | J. ; Clin. |
| T5 | 460-488 | Sentence | denotes | Proteomics 2007 , 1 , 325 ). |
| T6 | 489-646 | Sentence | denotes | In the current study, the results were confirmed and relatively quantified by using multiple reaction monitoring (MRM) on two peptide fragments of calcyclin. |
| T7 | 647-881 | Sentence | denotes | Cells were obtained from control (n = 5) and pre-eclamptic placental (n = 5) tissue collected by laser capture microdissection from formalin-fixed paraffin-embedded (FFPE) material treated with a solution to reverse formalin fixation. |
| T8 | 882-1028 | Sentence | denotes | Two calcyclin peptides with an extra glycine inserted in the middle of the amino acid sequence were synthesized and used as an internal reference. |
| T9 | 1029-1129 | Sentence | denotes | Data presented show that MRM on laser microdissected material from FFPE tissue material is possible. |
| T10 | 1130-1455 | Sentence | denotes | The developed MRM assay to study quantitative levels of proteins in FFPE laser microdissected cells using nonisotopic-labeled chemical analogs of mass tagged internal references showed that in pre-eclamptic patients elevated levels of calcyclin is observed in placental trophoblast cells compared to normal trophoblast cells. |
| T11 | 1456-1546 | Sentence | denotes | By immunohistochemistry, we were able to confirm this observation in a qualitative manner. |
UBERON-AE
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| PD-UBERON-AE-B_T1 | 116-124 | http://purl.obolibrary.org/obo/UBERON_0001987 | denotes | placenta |
| PD-UBERON-AE-B_T2 | 724-730 | http://purl.obolibrary.org/obo/UBERON_0000479 | denotes | tissue |
| PD-UBERON-AE-B_T3 | 1101-1107 | http://purl.obolibrary.org/obo/UBERON_0000479 | denotes | tissue |
| PD-UBERON-AE-B_T4 | 1400-1411 | http://purl.obolibrary.org/obo/UBERON_0000088 | denotes | trophoblast |
| PD-UBERON-AE-B_T5 | 1437-1448 | http://purl.obolibrary.org/obo/UBERON_0000088 | denotes | trophoblast |
performance-test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| PD-UBERON-AE-B_T1 | 724-730 | http://purl.obolibrary.org/obo/UBERON_0000479 | denotes | tissue |
| PD-UBERON-AE-B_T2 | 1101-1107 | http://purl.obolibrary.org/obo/UBERON_0000479 | denotes | tissue |
| PD-UBERON-AE-B_T3 | 116-124 | http://purl.obolibrary.org/obo/UBERON_0001987 | denotes | placenta |
| PD-UBERON-AE-B_T4 | 227-236 | http://purl.obolibrary.org/obo/UBERON_0001987 | denotes | placental |
| PD-UBERON-AE-B_T5 | 348-357 | http://purl.obolibrary.org/obo/UBERON_0001987 | denotes | placental |
| PD-UBERON-AE-B_T6 | 706-715 | http://purl.obolibrary.org/obo/UBERON_0001987 | denotes | placental |
| PD-UBERON-AE-B_T7 | 1390-1399 | http://purl.obolibrary.org/obo/UBERON_0001987 | denotes | placental |
| PD-UBERON-AE-B_T8 | 1400-1411 | http://purl.obolibrary.org/obo/UBERON_0000088 | denotes | trophoblast |
| PD-UBERON-AE-B_T9 | 1437-1448 | http://purl.obolibrary.org/obo/UBERON_0000088 | denotes | trophoblast |
HP-phenotype
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 250-273 | Phenotype | denotes | endothelial dysfunction | HP:0032654 |
mondo_disease
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 39-52 | Disease | denotes | pre-eclampsia | http://purl.obolibrary.org/obo/MONDO_0005081 |
| T2 | 148-161 | Disease | denotes | pre-eclampsia | http://purl.obolibrary.org/obo/MONDO_0005081 |
| T3 | 334-347 | Disease | denotes | pre-eclampsia | http://purl.obolibrary.org/obo/MONDO_0005081 |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 919-926 | OrganismTaxon | denotes | glycine | 3846 |
Anatomy-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 116-124 | Body_part | denotes | placenta | http://purl.obolibrary.org/obo/MAT_0000279 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 116-124 | Body_part | denotes | placenta | http://purl.obolibrary.org/obo/UBERON_0001987 |
| T2 | 724-730 | Body_part | denotes | tissue | http://purl.obolibrary.org/obo/UBERON_0000479 |
| T3 | 1101-1107 | Body_part | denotes | tissue | http://purl.obolibrary.org/obo/UBERON_0000479 |
| T4 | 1400-1417 | Body_part | denotes | trophoblast cells | http://purl.obolibrary.org/obo/CL_0000351 |
| T5 | 1437-1454 | Body_part | denotes | trophoblast cells | http://purl.obolibrary.org/obo/CL_0000351 |
CL-cell
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 1400-1417 | Cell | denotes | trophoblast cells | http://purl.obolibrary.org/obo/CL:0000351 |
| T2 | 1437-1454 | Cell | denotes | trophoblast cells | http://purl.obolibrary.org/obo/CL:0000351 |