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PubMed:21244006 JSONTXT

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GlyCosmos15-Species

Id Subject Object Predicate Lexical cue db_id
1 6-30 Species denotes Streptococcus pneumoniae 1313
15 69-93 Species denotes Streptococcus penumoniae
16 105-110 Species denotes human 9606
20 278-291 Species denotes S. pneumoniae
27 907-919 Species denotes pneumococcal

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 136-164 HP_0011947 denotes respiratory tract infections
T2 182-192 HP_0002858 denotes meningitis

GlyCosmos15-Glycan

Id Subject Object Predicate Lexical cue image
T1 498-504 Glycan denotes Neu5Ac https://api.glycosmos.org/wurcs2image/latest/png/binary/G76685HR
T2 681-687 Glycan denotes Neu5Ac https://api.glycosmos.org/wurcs2image/latest/png/binary/G76685HR
T3 873-879 Glycan denotes Neu5Ac https://api.glycosmos.org/wurcs2image/latest/png/binary/G76685HR

mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 6-30 Disease denotes Streptococcus pneumoniae http://purl.obolibrary.org/obo/MONDO_0005972
T2 136-164 Disease denotes respiratory tract infections http://purl.obolibrary.org/obo/MONDO_0024355
T3 182-192 Disease denotes meningitis http://purl.obolibrary.org/obo/MONDO_0004796|http://purl.obolibrary.org/obo/MONDO_0021108
T5 281-291 Disease denotes pneumoniae http://purl.obolibrary.org/obo/MONDO_0005249

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 182-192 Body_part denotes meningitis http://purl.obolibrary.org/obo/MAT_0000113

HP-phenotype

Id Subject Object Predicate Lexical cue hp_id
T1 20-30 Phenotype denotes pneumoniae HP:0002090
T2 136-164 Phenotype denotes respiratory tract infections HP:0011947
T3 182-192 Phenotype denotes meningitis HP:0001287
T4 281-291 Phenotype denotes pneumoniae HP:0002090

Glycan-GlyCosmos

Id Subject Object Predicate Lexical cue image
T1 498-504 Glycan denotes Neu5Ac https://api.glycosmos.org/wurcs2image/latest/png/binary/G76685HR
T2 681-687 Glycan denotes Neu5Ac https://api.glycosmos.org/wurcs2image/latest/png/binary/G76685HR
T3 873-879 Glycan denotes Neu5Ac https://api.glycosmos.org/wurcs2image/latest/png/binary/G76685HR

GlyCosmos15-HP

Id Subject Object Predicate Lexical cue hp_id
T1 20-30 Phenotype denotes pneumoniae HP:0002090
T2 136-164 Phenotype denotes respiratory tract infections HP:0011947
T3 182-192 Phenotype denotes meningitis HP:0001287
T4 281-291 Phenotype denotes pneumoniae HP:0002090

GlyCosmos15-NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 6-30 OrganismTaxon denotes Streptococcus pneumoniae 1313
T2 69-82 OrganismTaxon denotes Streptococcus 1301
T3 105-110 OrganismTaxon denotes human 9606

GlyCosmos15-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 136-153 Body_part denotes respiratory tract http://purl.obolibrary.org/obo/UBERON_0000065|http://purl.obolibrary.org/obo/UBERON_0000072

GlyCosmos15-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 6-30 Disease denotes Streptococcus pneumoniae MONDO:0005972
T2 136-164 Disease denotes respiratory tract infections MONDO:0024355
T3 182-192 Disease denotes meningitis MONDO:0004796|MONDO:0021108
T5 281-291 Disease denotes pneumoniae MONDO:0005249

GlyCosmos15-Sentences

Id Subject Object Predicate Lexical cue
T1 0-68 Sentence denotes Three Streptococcus pneumoniae sialidases: three different products.
T2 69-277 Sentence denotes Streptococcus penumoniae is a major human pathogen responsible for respiratory tract infections, septicemia, and meningitis and continues to produce numerous cases of disease with relatively high mortalities.
T3 278-419 Sentence denotes S. pneumoniae encodes up to three sialidases, NanA, NanB, and NanC, that have been implicated in pathogenesis and are potential drug targets.
T4 420-616 Sentence denotes NanA has been shown to be a promiscuous sialidase, hydrolyzing the removal of Neu5Ac from a variety of glycoconjugates with retention of configuration at the anomeric center, as we confirm by NMR.
T5 617-721 Sentence denotes NanB is an intramolecular trans-sialidase producing 2,7-anhydro-Neu5Ac selectively from α2,3-sialosides.
T6 722-880 Sentence denotes Here, we show that the first product of NanC is 2-deoxy-2,3-didehydro-N-acetylneuraminic acid (Neu5Ac2en) that can be slowly hydrated by the enzyme to Neu5Ac.
T7 881-1082 Sentence denotes We propose that the three pneumococcal sialidases share a common catalytic mechanism up to the final product formation step, and speculate on the roles of the enzymes in the lifecycle of the bacterium.

GlyCosmos15-FMA

Id Subject Object Predicate Lexical cue db_id
T1 136-153 Body_part denotes respiratory tract FMA:265130

GlyCosmos15-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 182-192 Body_part denotes meningitis http://purl.obolibrary.org/obo/MAT_0000113

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 6-30 OrganismTaxon denotes Streptococcus pneumoniae 1313
T2 69-82 OrganismTaxon denotes Streptococcus 1301
T3 105-110 OrganismTaxon denotes human 9606

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 136-153 Body_part denotes respiratory tract http://purl.obolibrary.org/obo/UBERON_0000065|http://purl.obolibrary.org/obo/UBERON_0000072