PubMed:21130729
Annnotations
Anatomy-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 57-63 | Body_part | denotes | artery | http://purl.obolibrary.org/obo/MAT_0000034 |
| T2 | 64-77 | Body_part | denotes | smooth muscle | http://purl.obolibrary.org/obo/MAT_0000303 |
| T3 | 92-98 | Body_part | denotes | artery | http://purl.obolibrary.org/obo/MAT_0000034 |
| T4 | 99-112 | Body_part | denotes | smooth muscle | http://purl.obolibrary.org/obo/MAT_0000303 |
| T5 | 709-722 | Body_part | denotes | smooth muscle | http://purl.obolibrary.org/obo/MAT_0000303 |
Glycan-GlyCosmos
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 1039-1042 | Glycan | denotes | GM1 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G48558GR |
| T2 | 1287-1290 | Glycan | denotes | GM1 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G48558GR |
GlyCosmos-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 1039-1042 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GM1 | http://www.glycoepitope.jp/epitopes/EP0050 |
| T2 | 1287-1290 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GM1 | http://www.glycoepitope.jp/epitopes/EP0050 |
GlyCosmos15-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 48-63 | Body_part | denotes | coronary artery | http://purl.obolibrary.org/obo/UBERON_0001621 |
| T2 | 64-77 | Body_part | denotes | smooth muscle | http://purl.obolibrary.org/obo/UBERON_0001135 |
| T3 | 83-98 | Body_part | denotes | coronary artery | http://purl.obolibrary.org/obo/UBERON_0001621 |
| T4 | 99-112 | Body_part | denotes | smooth muscle | http://purl.obolibrary.org/obo/UBERON_0001135 |
| T5 | 179-191 | Body_part | denotes | sarcoplasmic | http://purl.obolibrary.org/obo/GO_0016528 |
| T6 | 192-201 | Body_part | denotes | reticulum | http://purl.obolibrary.org/obo/UBERON_0007361 |
| T7 | 275-287 | Body_part | denotes | sarcoplasmic | http://purl.obolibrary.org/obo/GO_0016528 |
| T8 | 288-297 | Body_part | denotes | reticulum | http://purl.obolibrary.org/obo/UBERON_0007361 |
| T9 | 469-495 | Body_part | denotes | regions of plasma membrane | http://purl.obolibrary.org/obo/GO_0098590 |
| T10 | 542-550 | Body_part | denotes | membrane | http://purl.obolibrary.org/obo/GO_0016020|http://purl.obolibrary.org/obo/UBERON_0000094|http://purl.obolibrary.org/obo/UBERON_0000158 |
| T13 | 709-729 | Body_part | denotes | smooth muscle tissue | http://purl.obolibrary.org/obo/UBERON_0001135 |
| T14 | 927-942 | Body_part | denotes | plasma membrane | http://purl.obolibrary.org/obo/GO_0005886 |
| T15 | 1444-1452 | Body_part | denotes | membrane | http://purl.obolibrary.org/obo/GO_0016020|http://purl.obolibrary.org/obo/UBERON_0000094|http://purl.obolibrary.org/obo/UBERON_0000158 |
| T18 | 1811-1823 | Body_part | denotes | sarcoplasmic | http://purl.obolibrary.org/obo/GO_0016528 |
| T19 | 1824-1833 | Body_part | denotes | reticulum | http://purl.obolibrary.org/obo/UBERON_0007361 |
GlyCosmos15-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 57-63 | Body_part | denotes | artery | http://purl.obolibrary.org/obo/MAT_0000034 |
| T2 | 64-77 | Body_part | denotes | smooth muscle | http://purl.obolibrary.org/obo/MAT_0000303 |
| T3 | 92-98 | Body_part | denotes | artery | http://purl.obolibrary.org/obo/MAT_0000034 |
| T4 | 99-112 | Body_part | denotes | smooth muscle | http://purl.obolibrary.org/obo/MAT_0000303 |
| T5 | 709-722 | Body_part | denotes | smooth muscle | http://purl.obolibrary.org/obo/MAT_0000303 |
GlyCosmos15-Sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-78 | Sentence | denotes | Sodium-calcium exchanger and lipid rafts in pig coronary artery smooth muscle. |
| T2 | 79-219 | Sentence | denotes | Pig coronary artery smooth muscle expresses, among many other proteins, Na+-Ca²+-exchanger NCX1 and sarcoplasmic reticulum Ca²+ pump SERCA2. |
| T3 | 220-365 | Sentence | denotes | NCX1 has been proposed to play a role in refilling the sarcoplasmic reticulum Ca²+ pool suggesting a functional linkage between the two proteins. |
| T4 | 366-513 | Sentence | denotes | We hypothesized that this functional linkage may require close apposition of SERCA2 and NCX1 involving regions of plasma membrane like lipid rafts. |
| T5 | 514-613 | Sentence | denotes | Lipid rafts are specialized membrane microdomains that appear as platforms to co-localize proteins. |
| T6 | 614-865 | Sentence | denotes | To determine the distribution of NCX1, SERCA2 and lipid rafts, we isolated microsomes from the smooth muscle tissue, treated them with non-ionic detergent and obtained fractions of different densities by sucrose density gradient centrifugal flotation. |
| T7 | 866-1125 | Sentence | denotes | We examined the distribution of NCX1; SERCA2; non-lipid raft plasma membrane marker transferrin receptor protein; lipid raft markers caveolin-1, flotillin-2, prion protein, GM1-gangliosides and cholesterol; and cytoskeletal markers clathrin, actin and myosin. |
| T8 | 1126-1220 | Sentence | denotes | Distribution of markers identified two subsets of lipid rafts that differ in their components. |
| T9 | 1221-1335 | Sentence | denotes | One subset is rich in caveolin-1 and flotillin-2 and the other in GM1-gangliosides, prion protein and cholesterol. |
| T10 | 1336-1506 | Sentence | denotes | NCX1 distribution correlated strongly with SERCA2, caveolin-1 and flotillin-2, less strongly with the other membrane markers and negatively with the cytoskeletal markers. |
| T11 | 1507-1651 | Sentence | denotes | These experiments were repeated with a non-detergent method of treating microsomes with sonication at high pH and similar results were obtained. |
| T12 | 1652-1834 | Sentence | denotes | These observations are consistent with the observed functional linkage between NCX1 and SERCA2 and suggest a role for NCX1 in supplying Ca²+ for refilling the sarcoplasmic reticulum. |
GlyCosmos15-Glycan
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 1039-1042 | Glycan | denotes | GM1 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G48558GR |
| T2 | 1287-1290 | Glycan | denotes | GM1 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G48558GR |
GlyCosmos15-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 1039-1042 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GM1 | http://www.glycoepitope.jp/epitopes/EP0050 |
| T2 | 1287-1290 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GM1 | http://www.glycoepitope.jp/epitopes/EP0050 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 48-63 | Body_part | denotes | coronary artery | http://purl.obolibrary.org/obo/UBERON_0001621 |
| T2 | 64-77 | Body_part | denotes | smooth muscle | http://purl.obolibrary.org/obo/UBERON_0001135 |
| T3 | 83-98 | Body_part | denotes | coronary artery | http://purl.obolibrary.org/obo/UBERON_0001621 |
| T4 | 99-112 | Body_part | denotes | smooth muscle | http://purl.obolibrary.org/obo/UBERON_0001135 |
| T5 | 179-191 | Body_part | denotes | sarcoplasmic | http://purl.obolibrary.org/obo/GO_0016528 |
| T6 | 192-201 | Body_part | denotes | reticulum | http://purl.obolibrary.org/obo/UBERON_0007361 |
| T7 | 275-287 | Body_part | denotes | sarcoplasmic | http://purl.obolibrary.org/obo/GO_0016528 |
| T8 | 288-297 | Body_part | denotes | reticulum | http://purl.obolibrary.org/obo/UBERON_0007361 |
| T9 | 469-495 | Body_part | denotes | regions of plasma membrane | http://purl.obolibrary.org/obo/GO_0098590 |
| T10 | 542-550 | Body_part | denotes | membrane | http://purl.obolibrary.org/obo/GO_0016020|http://purl.obolibrary.org/obo/UBERON_0000094|http://purl.obolibrary.org/obo/UBERON_0000158 |
| T13 | 709-729 | Body_part | denotes | smooth muscle tissue | http://purl.obolibrary.org/obo/UBERON_0001135 |
| T14 | 927-942 | Body_part | denotes | plasma membrane | http://purl.obolibrary.org/obo/GO_0005886 |
| T15 | 1444-1452 | Body_part | denotes | membrane | http://purl.obolibrary.org/obo/GO_0016020|http://purl.obolibrary.org/obo/UBERON_0000094|http://purl.obolibrary.org/obo/UBERON_0000158 |
| T18 | 1811-1823 | Body_part | denotes | sarcoplasmic | http://purl.obolibrary.org/obo/GO_0016528 |
| T19 | 1824-1833 | Body_part | denotes | reticulum | http://purl.obolibrary.org/obo/UBERON_0007361 |