PubMed:2112575
Annnotations
jnlpba-st-training
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 18-23 | DNA | denotes | c-fos |
| T2 | 25-30 | DNA | denotes | c-jun |
| T3 | 36-47 | DNA | denotes | c-myc genes |
| T4 | 78-98 | cell_type | denotes | human lymphoid cells |
| T5 | 150-172 | DNA | denotes | nuclear protooncogenes |
| T6 | 173-178 | DNA | denotes | c-fos |
| T7 | 180-185 | DNA | denotes | c-jun |
| T8 | 191-196 | DNA | denotes | c-myc |
| T9 | 212-232 | cell_type | denotes | human lymphoid cells |
| T10 | 313-323 | RNA | denotes | c-myc mRNA |
| T11 | 334-372 | cell_line | denotes | pre-B (Hyon) and T (DND-41) cell lines |
| T12 | 469-483 | DNA | denotes | protooncogenes |
| T13 | 487-497 | cell_line | denotes | Hyon cells |
| T14 | 662-667 | DNA | denotes | c-fos |
| T15 | 672-683 | DNA | denotes | c-myc genes |
| T16 | 749-759 | cell_line | denotes | Hyon cells |
| T17 | 775-785 | RNA | denotes | c-myc mRNA |
| T18 | 875-885 | RNA | denotes | c-myc mRNA |
| T19 | 1000-1022 | DNA | denotes | nuclear protooncogenes |
| T20 | 1072-1094 | DNA | denotes | nuclear protooncogenes |
| T21 | 1121-1135 | cell_type | denotes | lymphoid cells |
semrep-sample
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| E1-ti-1 | 4-14 | cui:C0185117 | denotes | expression |
| E2-ti-1 | 18-23 | cui:C0085301 | denotes | c-fos |
| E3-ti-1 | 25-30 | cui:C0085942 | denotes | c-jun |
| E4-ti-1 | 36-47 | cui:C0079068 | denotes | c-myc genes |
| E5-ti-1 | 64-74 | cui:C0282498 | denotes | heat shock |
| E6-ti-1 | 78-83 | cui:C0020114 | denotes | human |
| E7-ti-1 | 84-98 | cui:C0086574 | denotes | lymphoid cells |
| T1 | 78-98 | PART_OF | denotes | human lymphoid cells |
| T2 | 75-77 | LOCATION_OF | denotes | in |
| T3 | 75-77 | LOCATION_OF | denotes | in |
| T4 | 75-77 | LOCATION_OF | denotes | in |
| E1-ab-1 | 104-110 | cui:C1280500 | denotes | effect |
| E2-ab-1 | 114-124 | cui:C0282498 | denotes | heat shock |
| E3-ab-1 | 132-142 | cui:C0185117 | denotes | expression |
| E4-ab-1 | 150-157 | cui:C0521447 | denotes | nuclear |
| E5-ab-1 | 158-178 | cui:C0085940 | denotes | protooncogenes c-fos |
| E6-ab-1 | 180-185 | cui:C0085942 | denotes | c-jun |
| E7-ab-1 | 191-196 | cui:C0079068 | denotes | c-myc |
| E8-ab-1 | 212-217 | cui:C0020114 | denotes | human |
| E9-ab-1 | 218-232 | cui:C0086574 | denotes | lymphoid cells |
| T5 | 104-110 | AFFECTS | denotes | effect |
| T6 | 104-110 | AFFECTS | denotes | effect |
| T7 | 104-110 | AFFECTS | denotes | effect |
| T8 | 212-232 | PART_OF | denotes | human lymphoid cells |
| E1-ab-2 | 234-244 | cui:C0282498 | denotes | Heat shock |
| E2-ab-2 | 255-263 | cui:C0442805 | denotes | increase |
| E3-ab-2 | 267-272 | cui:C0085301 | denotes | c-fos |
| E4-ab-2 | 277-282 | cui:C0085942 | denotes | c-jun |
| E5-ab-2 | 283-287 | cui:C0035696 | denotes | mRNA |
| E6-ab-2 | 288-294 | cui:C0441889 | denotes | levels |
| E7-ab-2 | 301-309 | cui:C0547047 | denotes | decrease |
| E8-ab-2 | 313-318 | cui:C0079068 | denotes | c-myc |
| E9-ab-2 | 319-323 | cui:C0035696 | denotes | mRNA |
| E10-ab-2 | 324-330 | cui:C0441889 | denotes | levels |
| E11-ab-2 | 334-337 | cui:C0740175 | denotes | pre |
| E12-ab-2 | 362-372 | cui:C0007600 | denotes | cell lines |
| E13-ab-2 | 404-410 | cui:C0205307 | denotes | normal |
| E14-ab-2 | 411-416 | cui:C0020114 | denotes | human |
| E15-ab-2 | 417-427 | cui:C0814999 | denotes | thymocytes |
| T9 | 310-312 | COEXISTS_WITH | denotes | in |
| T10 | 411-427 | PART_OF | denotes | human thymocytes |
| E1-ab-3 | 433-440 | cui:C0392747 | denotes | changes |
| E2-ab-3 | 448-452 | cui:C0035696 | denotes | mRNA |
| E3-ab-3 | 453-459 | cui:C0441889 | denotes | levels |
| E4-ab-3 | 469-483 | cui:C0033713 | denotes | protooncogenes |
| E5-ab-3 | 492-497 | cui:C0007634 | denotes | cells |
| E6-ab-3 | 503-507 | cui:C0205393 | denotes | most |
| E7-ab-3 | 532-541 | cui:C0439237 | denotes | degrees C |
| T11 | 484-486 | LOCATION_OF | denotes | in |
| E1-ab-4 | 543-550 | cui:C0022702 | denotes | kinetic |
| E2-ab-4 | 551-559 | cui:C0936012 | denotes | analysis |
| E3-ab-4 | 582-589 | cui:C0392747 | denotes | changes |
| E4-ab-4 | 615-621 | cui:C0456693 | denotes | 30 min |
| E5-ab-4 | 625-635 | cui:C0282498 | denotes | heat shock |
| E1-ab-5 | 637-644 | cui:C0205349 | denotes | Altered |
| E2-ab-5 | 645-658 | cui:C0040649 | denotes | transcription |
| E3-ab-5 | 662-667 | cui:C0085301 | denotes | c-fos |
| E4-ab-5 | 672-683 | cui:C0079068 | denotes | c-myc genes |
| E5-ab-5 | 700-706 | cui:C1280500 | denotes | effect |
| E6-ab-5 | 710-720 | cui:C0282498 | denotes | heat shock |
| T12 | 700-706 | AFFECTS | denotes | effect |
| T13 | 700-706 | AFFECTS | denotes | effect |
| E1-ab-6 | 735-745 | cui:C0282498 | denotes | heat shock |
| E2-ab-6 | 754-759 | cui:C0007634 | denotes | cells |
| E3-ab-6 | 775-780 | cui:C0079068 | denotes | c-myc |
| E4-ab-6 | 781-785 | cui:C0035696 | denotes | mRNA |
| E5-ab-6 | 795-805 | cui:C0442808 | denotes | increasing |
| E6-ab-6 | 810-819 | cui:C0018517 | denotes | half-life |
| E7-ab-6 | 834-837 | cui:C1524031 | denotes | min |
| E1-ab-7 | 843-850 | cui:C1561607 | denotes | overall |
| E2-ab-7 | 851-857 | cui:C1280500 | denotes | effect |
| E3-ab-7 | 861-871 | cui:C0282498 | denotes | heat shock |
| E4-ab-7 | 875-880 | cui:C0079068 | denotes | c-myc |
| E5-ab-7 | 881-885 | cui:C0035696 | denotes | mRNA |
| E6-ab-7 | 908-914 | cui:C0522501 | denotes | marked |
| E7-ab-7 | 933-946 | cui:C0040649 | denotes | transcription |
| E1-ab-8 | 954-961 | cui:C1274040 | denotes | results |
| E2-ab-8 | 983-996 | cui:C0040649 | denotes | transcription |
| E3-ab-8 | 1000-1007 | cui:C0521447 | denotes | nuclear |
| E4-ab-8 | 1008-1022 | cui:C0033713 | denotes | protooncogenes |
| E5-ab-8 | 1039-1049 | cui:C0282498 | denotes | heat shock |
| E6-ab-8 | 1063-1067 | cui:C0035820 | denotes | role |
| E7-ab-8 | 1072-1079 | cui:C0521447 | denotes | nuclear |
| E8-ab-8 | 1080-1094 | cui:C0033713 | denotes | protooncogenes |
| E9-ab-8 | 1102-1117 | cui:C0149784 | denotes | stress response |
| E10-ab-8 | 1121-1135 | cui:C0086574 | denotes | lymphoid cells |
| T14 | 1026-1035 | AFFECTS | denotes | regulated |
| T15 | 1095-1097 | COEXISTS_WITH | denotes | in |
| R1 | E7-ti-1 | T1 | subjectOf | lymphoid cells,human lymphoid cells |
| R2 | E6-ti-1 | T1 | objectOf | human,human lymphoid cells |
| R3 | E7-ti-1 | T2 | subjectOf | lymphoid cells,in |
| R4 | E4-ti-1 | T2 | objectOf | c-myc genes,in |
| R5 | E7-ti-1 | T3 | subjectOf | lymphoid cells,in |
| R6 | E3-ti-1 | T3 | objectOf | c-jun,in |
| R7 | E7-ti-1 | T4 | subjectOf | lymphoid cells,in |
| R8 | E2-ti-1 | T4 | objectOf | c-fos,in |
| R9 | E5-ab-1 | T5 | subjectOf | protooncogenes c-fos,effect |
| R10 | E2-ab-1 | T5 | objectOf | heat shock,effect |
| R11 | E7-ab-1 | T6 | subjectOf | c-myc,effect |
| R12 | E2-ab-1 | T6 | objectOf | heat shock,effect |
| R13 | E6-ab-1 | T7 | subjectOf | c-jun,effect |
| R14 | E2-ab-1 | T7 | objectOf | heat shock,effect |
| R15 | E9-ab-1 | T8 | subjectOf | lymphoid cells,human lymphoid cells |
| R16 | E8-ab-1 | T8 | objectOf | human,human lymphoid cells |
| R17 | E4-ab-2 | T9 | subjectOf | c-jun,in |
| R18 | E8-ab-2 | T9 | objectOf | c-myc,in |
| R19 | E15-ab-2 | T10 | subjectOf | thymocytes,human thymocytes |
| R20 | E14-ab-2 | T10 | objectOf | human,human thymocytes |
| R21 | E5-ab-3 | T11 | subjectOf | cells,in |
| R22 | E4-ab-3 | T11 | objectOf | protooncogenes,in |
| R23 | E4-ab-5 | T12 | subjectOf | c-myc genes,effect |
| R24 | E6-ab-5 | T12 | objectOf | heat shock,effect |
| R25 | E3-ab-5 | T13 | subjectOf | c-fos,effect |
| R26 | E6-ab-5 | T13 | objectOf | heat shock,effect |
| R27 | E5-ab-8 | T14 | subjectOf | heat shock,regulated |
| R28 | E2-ab-8 | T14 | objectOf | transcription,regulated |
| R29 | E2-ab-8 | T15 | subjectOf | transcription,in |
| R30 | E9-ab-8 | T15 | objectOf | stress response,in |
pubmed-sentences-benchmark
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| S1 | 0-99 | Sentence | denotes | The expression of c-fos, c-jun, and c-myc genes is regulated by heat shock in human lymphoid cells. |
| S2 | 100-233 | Sentence | denotes | The effect of heat shock on the expression of the nuclear protooncogenes c-fos, c-jun, and c-myc was studied in human lymphoid cells. |
| S3 | 234-428 | Sentence | denotes | Heat shock caused an increase in c-fos and c-jun mRNA levels and a decrease in c-myc mRNA levels in pre-B (Hyon) and T (DND-41) cell lines as well as in freshly isolated normal human thymocytes. |
| S4 | 429-636 | Sentence | denotes | The changes in the mRNA levels of these protooncogenes in Hyon cells were most pronounced at 42 and 43 degrees C; kinetic analysis demonstrated that the changes could be detected within 30 min of heat shock. |
| S5 | 637-721 | Sentence | denotes | Altered transcription of c-fos and c-myc genes was the primary effect of heat shock. |
| S6 | 722-838 | Sentence | denotes | Secondarily, heat shock of Hyon cells stabilized the c-myc mRNA level by increasing its half-life from 24 to 45 min. |
| S7 | 839-947 | Sentence | denotes | The overall effect of heat shock on c-myc mRNA level, however, was a marked inhibition of its transcription. |
| S8 | 948-1136 | Sentence | denotes | These results demonstrate that the transcription of nuclear protooncogenes is regulated by heat shock indicating a role for nuclear protooncogenes in the stress response of lymphoid cells. |
genia-medco-coref
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| C2 | 18-47 | NP | denotes | c-fos, c-jun, and c-myc genes |
| C1 | 0-47 | NP | denotes | The expression of c-fos, c-jun, and c-myc genes |
| C3 | 64-74 | NP | denotes | heat shock |
| C4 | 78-98 | NP | denotes | human lymphoid cells |
| C5 | 114-124 | NP | denotes | heat shock |
| C7 | 146-196 | NP | denotes | the nuclear protooncogenes c-fos, c-jun, and c-myc |
| C6 | 128-196 | NP | denotes | the expression of the nuclear protooncogenes c-fos, c-jun, and c-myc |
| C8 | 212-232 | NP | denotes | human lymphoid cells |
| C9 | 234-244 | NP | denotes | Heat shock |
| C11 | 463-483 | NP | denotes | these protooncogenes |
| C12 | 487-497 | NP | denotes | Hyon cells |
| C10 | 429-497 | NP | denotes | The changes in the mRNA levels of these protooncogenes in Hyon cells |
| C13 | 578-589 | NP | denotes | the changes |
| C14 | 625-635 | NP | denotes | heat shock |
| C15 | 710-720 | NP | denotes | heat shock |
| C16 | 735-745 | NP | denotes | heat shock |
| C17 | 749-759 | NP | denotes | Hyon cells |
| C18 | 771-791 | NP | denotes | the c-myc mRNA level |
| C19 | 861-871 | NP | denotes | heat shock |
| C20 | 875-891 | NP | denotes | c-myc mRNA level |
| C21 | 929-932 | NP | denotes | its |
| C22 | 1000-1022 | NP | denotes | nuclear protooncogenes |
| C23 | 1039-1049 | NP | denotes | heat shock |
| C24 | 1072-1094 | NP | denotes | nuclear protooncogenes |
| C25 | 1121-1135 | NP | denotes | lymphoid cells |
| R1 | C5 | C3 | coref-ident | heat shock,heat shock |
| R2 | C7 | C2 | coref-ident | "the nuclear protooncogenes c-fos, c-jun, and c-myc","c-fos, c-jun, and c-myc genes" |
| R3 | C6 | C1 | coref-ident | "the expression of the nuclear protooncogenes c-fos, c-jun, and c-myc","The expression of c-fos, c-jun, and c-myc genes" |
| R4 | C8 | C4 | coref-ident | human lymphoid cells,human lymphoid cells |
| R5 | C9 | C5 | coref-ident | Heat shock,heat shock |
| R6 | C11 | C7 | coref-ident | these protooncogenes,"the nuclear protooncogenes c-fos, c-jun, and c-myc" |
| R7 | C13 | C10 | coref-ident | the changes,The changes in the mRNA levels of these protooncogenes in Hyon cells |
| R8 | C14 | C9 | coref-ident | heat shock,Heat shock |
| R9 | C15 | C14 | coref-ident | heat shock,heat shock |
| R10 | C16 | C15 | coref-ident | heat shock,heat shock |
| R11 | C17 | C12 | coref-ident | Hyon cells,Hyon cells |
| R12 | C19 | C16 | coref-ident | heat shock,heat shock |
| R13 | C20 | C18 | coref-ident | c-myc mRNA level,the c-myc mRNA level |
| R14 | C21 | C20 | coref-pron | its,c-myc mRNA level |
| R15 | C22 | C11 | coref-ident | nuclear protooncogenes,these protooncogenes |
| R16 | C23 | C19 | coref-ident | heat shock,heat shock |
| R17 | C24 | C22 | coref-ident | nuclear protooncogenes,nuclear protooncogenes |
| R18 | C25 | C8 | coref-ident | lymphoid cells,human lymphoid cells |
GENIAcorpus
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 18-23 | DNA_domain_or_region | denotes | c-fos |
| T2 | 25-30 | DNA_domain_or_region | denotes | c-jun |
| T3 | 36-47 | DNA_domain_or_region | denotes | c-myc genes |
| T4 | 64-74 | other_name | denotes | heat shock |
| T5 | 78-98 | cell_type | denotes | human lymphoid cells |
| T6 | 114-124 | other_name | denotes | heat shock |
| T7 | 150-172 | DNA_family_or_group | denotes | nuclear protooncogenes |
| T8 | 173-178 | DNA_domain_or_region | denotes | c-fos |
| T9 | 180-185 | DNA_domain_or_region | denotes | c-jun |
| T10 | 191-196 | DNA_domain_or_region | denotes | c-myc |
| T11 | 212-232 | cell_type | denotes | human lymphoid cells |
| T12 | 313-318 | DNA_domain_or_region | denotes | c-myc |
| T13 | 448-459 | other_name | denotes | mRNA levels |
| T14 | 469-483 | DNA_family_or_group | denotes | protooncogenes |
| T15 | 487-497 | cell_line | denotes | Hyon cells |
| T16 | 625-635 | other_name | denotes | heat shock |
| T17 | 662-667 | DNA_domain_or_region | denotes | c-fos |
| T18 | 672-677 | DNA_domain_or_region | denotes | c-myc |
| T19 | 710-720 | other_name | denotes | heat shock |
| T20 | 735-745 | other_name | denotes | heat shock |
| T21 | 749-759 | cell_line | denotes | Hyon cells |
| T22 | 775-780 | DNA_domain_or_region | denotes | c-myc |
| T23 | 810-819 | other_name | denotes | half-life |
| T24 | 861-871 | other_name | denotes | heat shock |
| T25 | 875-880 | DNA_domain_or_region | denotes | c-myc |
| T26 | 933-946 | other_name | denotes | transcription |
| T27 | 983-996 | other_name | denotes | transcription |
| T28 | 1000-1007 | DNA_domain_or_region | denotes | nuclear |
| T29 | 1008-1022 | DNA_family_or_group | denotes | protooncogenes |
| T30 | 1039-1049 | other_name | denotes | heat shock |
| T31 | 1072-1079 | DNA_family_or_group | denotes | nuclear |
| T32 | 1080-1094 | DNA_family_or_group | denotes | protooncogenes |
| T33 | 1121-1135 | cell_type | denotes | lymphoid cells |
metamap-sample
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 673-684 | C0079068 | denotes | -myc genes |
| T2 | 37-48 | C0079068 | denotes | -myc genes |
| T3 | 412-417 | C0086418 | denotes | uman |
| T4 | 79-84 | C0086418 | denotes | uman |
| T5 | 1122-1136 | C0086574 | denotes | ymphoid cells. |
| T6 | 219-233 | C0086574 | denotes | ymphoid cells. |
| T7 | 85-99 | C0086574 | denotes | ymphoid cells. |
| T8 | 1040-1050 | C0282498 | denotes | eat shock |
| T9 | 862-872 | C0282498 | denotes | eat shock |
| T10 | 736-746 | C0282498 | denotes | eat shock |
| T11 | 711-721 | C0282498 | denotes | eat shock. |
| T12 | 626-636 | C0282498 | denotes | eat shock. |
| T13 | 235-245 | C0282498 | denotes | eat shock |
| T14 | 115-125 | C0282498 | denotes | eat shock |
| T15 | 65-75 | C0282498 | denotes | eat shock |
| T16 | 1027-1035 | C0851285 | denotes | egulated |
| T17 | 52-61 | C0851285 | denotes | egulated |
| T18 | 278-283 | C0162508 | denotes | -jun |
| T19 | 181-186 | C0162508 | denotes | -jun, |
| T20 | 26-31 | C0162508 | denotes | -jun, |
| T21 | 133-143 | C0185117 | denotes | xpression |
| T22 | 5-15 | C0185117 | denotes | xpression |
| T23 | 85-93 | C1518071 | denotes | ymphoid |
| T24 | 470-484 | C0033713 | denotes | rotooncogenes |
| T25 | 882-886 | C0035696 | denotes | RNA |
| T26 | 782-786 | C0035696 | denotes | RNA |
| T27 | 449-453 | C0035696 | denotes | RNA |
| T28 | 984-997 | C0040649 | denotes | ranscription |
| T29 | 934-947 | C0040649 | denotes | ranscription. |
| T30 | 646-659 | C0040649 | denotes | ranscription |
| T31 | 867-872 | C0036974 | denotes | hock |
| T32 | 716-721 | C0036974 | denotes | hock. |
| T33 | 120-125 | C0036974 | denotes | hock |
| T34 | 418-428 | C0814999 | denotes | hymocytes. |
| T35 | 430-441 | C0025320 | denotes | he changes |
| T36 | 887-892 | C0441889 | denotes | evel, |
| T37 | 787-792 | C0441889 | denotes | evel |
| T38 | 454-460 | C0441889 | denotes | evels |
| T39 | 552-560 | C1524024 | denotes | nalysis |
| T40 | 363-373 | C0007600 | denotes | ell lines |
| T41 | 852-858 | C1280500 | denotes | ffect |
| T42 | 701-707 | C1280500 | denotes | ffect |
| T43 | 105-111 | C1280500 | denotes | ffect |
| T44 | 151-158 | C0521447 | denotes | uclear |
| T45 | 246-252 | C0015127 | denotes | aused |
| T46 | 811-820 | C0018517 | denotes | alf-life |
| T47 | 544-551 | C0022702 | denotes | inetic |
| T48 | 844-851 | C0282416 | denotes | verall |
| T49 | 876-881 | C0086661 | denotes | -myc |
| T50 | 192-197 | C0086661 | denotes | -myc |
| T51 | 755-760 | C0007634 | denotes | ells |
| T52 | 493-498 | C0007634 | denotes | ells |
| T53 | 396-404 | C1548221 | denotes | solated |
| T54 | 583-590 | C0443172 | denotes | hanges |
| T55 | 504-508 | C0205393 | denotes | ost |
| T56 | 761-771 | C0184512 | denotes | tabilized |
| T57 | 1103-1117 | C0149784 | denotes | tress response |
| T58 | 955-962 | C1274040 | denotes | esults |
| T59 | 533-542 | C0439237 | denotes | egrees C; |
| T60 | 835-838 | C0702093 | denotes | in. |
| T61 | 352-353 | C2603360 | denotes | |
| T62 | 616-622 | C1442458 | denotes | 0 min |
| T63 | 1064-1068 | C1705810 | denotes | ole |
| T64 | 377-381 | C0205170 | denotes | ell |
| T65 | 256-264 | C0442805 | denotes | ncrease |
| T66 | 916-926 | C0021469 | denotes | nhibition |
| T67 | 302-310 | C0547047 | denotes | ecrease |
| T68 | 600-608 | C0442726 | denotes | etected |
| T69 | 335-340 | C1292769 | denotes | re-B |
| T70 | 405-410 | C0439166 | denotes | ormal |
| T71 | 638-644 | C0392747 | denotes | ltered |
| T72 | 909-915 | C0522501 | denotes | arked |
| T73 | 693-700 | C0205225 | denotes | rimary |
| T74 | 796-806 | C0442808 | denotes | ncreasing |