PubMed:2111191 JSON TXT

Annnotations TAB JSON ListView MergeView

Id	Subject	Object	Predicate	Lexical cue
T1	58-87	cell_type	denotes	human tonsillar T-lymphocytes
T2	106-135	cell_type	denotes	human tonsillar T-lymphocytes
T3	221-244	protein	denotes	glucocorticoid receptor
T4	246-248	protein	denotes	GR
T5	461-480	protein	denotes	phytohaemagglutinin
T6	482-485	protein	denotes	PHA
T7	589-592	protein	denotes	PHA
T8	737-741	protein	denotes	-PHA

Id	Subject	Object	Predicate	Lexical cue
S1	0-88	Sentence	denotes	Effects of mitogenic agents upon glucocorticoid action in human tonsillar T-lymphocytes.
S2	89-314	Sentence	denotes	The treatment of human tonsillar T-lymphocytes with 4-phorbol 12-myristate 13-acetate (PMA), resulted in about two fold increase in glucocorticoid receptor (GR) number, without any significant change in the receptor affinity.
S3	315-374	Sentence	denotes	This increase disappeared in the presence of cycloheximide.
S4	375-540	Sentence	denotes	Alone, PMA and calcium ionophore A23187 did not affect, but together stimulated, like phytohaemagglutinin (PHA), leucine and, in particular, thymidine incorporation.
S5	541-593	Sentence	denotes	PMA enhanced slightly the stimulatory effect of PHA.
S6	594-811	Sentence	denotes	Alone, these agents failed to alter the suppressive effect of dexamethasone on thymidine and leucine incorporation; however, PMA-A23187 and PMA-PHA combinations appeared to antagonize the suppression by dexamethasone.

Id	Subject	Object	Predicate	Lexical cue
C1	58-87	NP	denotes	human tonsillar T-lymphocytes
C2	106-135	NP	denotes	human tonsillar T-lymphocytes
C3	141-180	NP	denotes	4-phorbol 12-myristate 13-acetate (PMA)
C4	200-256	NP	denotes	two fold increase in glucocorticoid receptor (GR) number
C5	315-328	NP	denotes	This increase
C6	382-385	NP	denotes	PMA
C8	461-486	NP	denotes	phytohaemagglutinin (PHA)
C9	488-539	NP	denotes	leucine and, in particular, thymidine incorporation
C7	461-539	NP	denotes	phytohaemagglutinin (PHA), leucine and, in particular, thymidine incorporation
C10	541-544	NP	denotes	PMA
C11	589-592	NP	denotes	PHA
C12	601-613	NP	denotes	these agents
C13	656-669	NP	denotes	dexamethasone
C14	673-708	NP	denotes	thymidine and leucine incorporation
C15	797-810	NP	denotes	dexamethasone
R1	C2	C1	coref-ident	human tonsillar T-lymphocytes,human tonsillar T-lymphocytes
R2	C5	C4	coref-ident	This increase,two fold increase in glucocorticoid receptor (GR) number
R3	C6	C3	coref-ident	PMA,4-phorbol 12-myristate 13-acetate (PMA)
R4	C10	C6	coref-ident	PMA,PMA
R5	C11	C8	coref-ident	PHA,phytohaemagglutinin (PHA)
R6	C12	C7	coref-ident	these agents,"phytohaemagglutinin (PHA), leucine and, in particular, thymidine incorporation"
R7	C14	C9	coref-ident	thymidine and leucine incorporation,"leucine and, in particular, thymidine incorporation"
R8	C15	C13	coref-ident	dexamethasone,dexamethasone

Id	Subject	Object	Predicate	Lexical cue
T1	11-27	other_name	denotes	mitogenic agents
T2	33-47	lipid	denotes	glucocorticoid
T3	58-76	cell_type	denotes	human tonsillar T-
T4	76-87	cell_type	denotes	lymphocytes
T5	106-124	cell_type	denotes	human tonsillar T-
T6	124-135	cell_type	denotes	lymphocytes
T7	141-174	other_organic_compound	denotes	4-phorbol 12-myristate 13-acetate
T8	176-179	other_organic_compound	denotes	PMA
T9	221-235	lipid	denotes	glucocorticoid
T10	246-248	protein_family_or_group	denotes	GR
T11	296-313	other_name	denotes	receptor affinity
T12	360-373	other_organic_compound	denotes	cycloheximide
T13	382-385	other_organic_compound	denotes	PMA
T14	390-414	other_organic_compound	denotes	calcium ionophore A23187
T15	461-480	protein_molecule	denotes	phytohaemagglutinin
T16	482-485	protein_molecule	denotes	PHA
T17	488-495	amino_acid_monomer	denotes	leucine
T18	516-525	nucleotide	denotes	thymidine
T19	541-544	other_organic_compound	denotes	PMA
T20	589-592	protein_molecule	denotes	PHA
T21	656-669	lipid	denotes	dexamethasone
T22	673-682	nucleotide	denotes	thymidine
T23	687-694	amino_acid_monomer	denotes	leucine
T24	719-722	other_organic_compound	denotes	PMA
T25	734-737	other_organic_compound	denotes	PMA
T26	737-741	protein_molecule	denotes	-PHA
T27	797-810	lipid	denotes	dexamethasone