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PubMed:20855471 JSONTXT

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GlyCosmos15-Species

Id Subject Object Predicate Lexical cue db_id
1 40-44 Species denotes mice 10090
31 439-443 Species denotes mice 10090
35 853-857 Species denotes mice 10090
38 1219-1223 Species denotes mice 10090
43 1469-1473 Species denotes mice 10090
45 1513-1517 Species denotes mice 10090

Glycan-Motif

Id Subject Object Predicate Lexical cue
T1 1304-1310 https://glytoucan.org/Structures/Glycans/G00031MO denotes core 1
T2 1581-1587 https://glytoucan.org/Structures/Glycans/G00031MO denotes core 1

GlyCosmos6-Glycan-Motif-Image

Id Subject Object Predicate Lexical cue image
T1 58-64 Glycan_Motif denotes core 2 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00033MO
T2 109-115 Glycan_Motif denotes Core 2 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00033MO
T3 310-316 Glycan_Motif denotes core 2 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00033MO
T4 377-383 Glycan_Motif denotes core 4 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00037MO
T5 581-587 Glycan_Motif denotes core 2 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00033MO
T6 1249-1255 Glycan_Motif denotes core 2 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00033MO
T7 1304-1310 Glycan_Motif denotes core 1 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00031MO
T8 1374-1380 Glycan_Motif denotes core 2 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00033MO
T9 1551-1557 Glycan_Motif denotes core 2 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00033MO
T10 1581-1587 Glycan_Motif denotes core 1 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00031MO

GlyCosmos6-Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 1304-1310 https://glytoucan.org/Structures/Glycans/G00031MO denotes core 1
T2 1581-1587 https://glytoucan.org/Structures/Glycans/G00031MO denotes core 1

Glycosmos6-MAT

Id Subject Object Predicate Lexical cue
T1 703-708 http://purl.obolibrary.org/obo/MAT_0000526 denotes colon
T2 710-725 http://purl.obolibrary.org/obo/MAT_0000047 denotes small intestine
T3 716-725 http://purl.obolibrary.org/obo/MAT_0000043 denotes intestine
T4 727-734 http://purl.obolibrary.org/obo/MAT_0000051 denotes stomach
T5 736-742 http://purl.obolibrary.org/obo/MAT_0000119 denotes kidney
T6 744-751 http://purl.obolibrary.org/obo/MAT_0000081 denotes thyroid
T7 752-759 http://purl.obolibrary.org/obo/MAT_0000137 denotes trachea
T8 764-770 http://purl.obolibrary.org/obo/MAT_0000080 denotes thymus
T9 1311-1319 http://purl.obolibrary.org/obo/MAT_0000086 denotes antennae
T10 1338-1345 http://purl.obolibrary.org/obo/MAT_0000051 denotes stomach
T11 1354-1359 http://purl.obolibrary.org/obo/MAT_0000526 denotes colon
T12 1588-1596 http://purl.obolibrary.org/obo/MAT_0000086 denotes antennae
T13 1778-1785 http://purl.obolibrary.org/obo/MAT_0000051 denotes stomach
T14 1889-1894 http://purl.obolibrary.org/obo/MAT_0000526 denotes colon

ICD10

Id Subject Object Predicate Lexical cue
T1 744-751 http://purl.bioontology.org/ontology/ICD10/E06 denotes thyroid
T2 744-751 http://purl.bioontology.org/ontology/ICD10/E06.9 denotes thyroid

GlycoBiology-FMA

Id Subject Object Predicate Lexical cue
_T1 400-408 FMAID:226027 denotes branches
_T2 400-408 FMAID:226028 denotes branches
_T3 527-552 FMAID:166102 denotes biological and structural
_T4 703-708 FMAID:14543 denotes colon
_T5 703-708 FMAID:104231 denotes colon
_T6 710-725 FMAID:204388 denotes small intestine
_T7 710-725 FMAID:209219 denotes small intestine
_T8 710-725 FMAID:104314 denotes small intestine
_T9 710-725 FMAID:7200 denotes small intestine
_T10 710-725 FMAID:93676 denotes small intestine
_T11 716-725 FMAID:93674 denotes intestine
_T12 716-725 FMAID:226991 denotes intestine
_T13 716-725 FMAID:7199 denotes intestine
_T14 727-734 FMAID:7148 denotes stomach
_T15 727-734 FMAID:93576 denotes stomach
_T16 736-742 FMAID:93681 denotes kidney
_T17 736-742 FMAID:7203 denotes kidney
_T18 744-751 FMAID:13344 denotes thyroid
_T19 744-751 FMAID:102701 denotes thyroid
_T20 752-759 FMAID:7394 denotes trachea
_T21 752-759 FMAID:94012 denotes trachea
_T22 764-770 FMAID:9607 denotes thymus
_T23 764-770 FMAID:97496 denotes thymus
_T24 1068-1077 FMAID:226027 denotes branching
_T25 1068-1077 FMAID:226028 denotes branching
_T26 1190-1197 FMAID:256050 denotes tissues
_T27 1292-1300 FMAID:226028 denotes branches
_T28 1292-1300 FMAID:226027 denotes branches
_T29 1338-1345 FMAID:93576 denotes stomach
_T30 1338-1345 FMAID:7148 denotes stomach
_T31 1354-1359 FMAID:104231 denotes colon
_T32 1354-1359 FMAID:14543 denotes colon
_T33 1438-1445 FMAID:256050 denotes tissues
_T34 1572-1580 FMAID:226028 denotes branched
_T35 1572-1580 FMAID:226027 denotes branched
_T36 1778-1785 FMAID:93576 denotes stomach
_T37 1778-1785 FMAID:7148 denotes stomach
_T38 1889-1894 FMAID:104231 denotes colon
_T39 1889-1894 FMAID:14543 denotes colon
_T40 1895-1902 FMAID:256050 denotes tissues
_T41 1943-1954 FMAID:82780 denotes glycolipids
_T42 1943-1954 FMAID:196773 denotes glycolipids

uniprot-human

Id Subject Object Predicate Lexical cue
T1 75-107 http://www.uniprot.org/uniprot/Q06430 denotes N-acetylglucosaminyltransferases
T2 121-152 http://www.uniprot.org/uniprot/Q06430 denotes N-acetylglucosaminyltransferase
T3 75-107 http://www.uniprot.org/uniprot/Q8N0V5 denotes N-acetylglucosaminyltransferases
T4 121-152 http://www.uniprot.org/uniprot/Q8N0V5 denotes N-acetylglucosaminyltransferase
T5 75-107 http://www.uniprot.org/uniprot/Q8NFS9 denotes N-acetylglucosaminyltransferases
T6 121-152 http://www.uniprot.org/uniprot/Q8NFS9 denotes N-acetylglucosaminyltransferase
T7 213-219 http://www.uniprot.org/uniprot/Q9P109 denotes C2GnT3
T8 796-802 http://www.uniprot.org/uniprot/Q9P109 denotes C2GnT3
T9 1453-1459 http://www.uniprot.org/uniprot/Q9P109 denotes C2GnT3

uniprot-mouse

Id Subject Object Predicate Lexical cue
T1 75-107 http://www.uniprot.org/uniprot/P97402 denotes N-acetylglucosaminyltransferases
T2 121-152 http://www.uniprot.org/uniprot/P97402 denotes N-acetylglucosaminyltransferase
T3 213-219 http://www.uniprot.org/uniprot/E9Q649 denotes C2GnT3
T4 796-802 http://www.uniprot.org/uniprot/E9Q649 denotes C2GnT3
T5 1453-1459 http://www.uniprot.org/uniprot/E9Q649 denotes C2GnT3

GlycoBiology-NCBITAXON

Id Subject Object Predicate Lexical cue
T1 66-70 http://purl.bioontology.org/ontology/NCBITAXON/3554 denotes beta
T2 66-70 http://purl.bioontology.org/ontology/NCBITAXON/158455 denotes beta
T3 752-759 http://purl.bioontology.org/ontology/NCBITAXON/988164 denotes trachea
T4 764-770 http://purl.bioontology.org/ontology/NCBITAXON/49990 denotes thymus
T5 1190-1197 http://purl.bioontology.org/ontology/STY/T024 denotes tissues
T6 1311-1319 http://purl.bioontology.org/ontology/NCBITAXON/293542 denotes antennae
T7 1438-1445 http://purl.bioontology.org/ontology/STY/T024 denotes tissues
T8 1588-1596 http://purl.bioontology.org/ontology/NCBITAXON/293542 denotes antennae
T9 1895-1902 http://purl.bioontology.org/ontology/STY/T024 denotes tissues

GO-BP

Id Subject Object Predicate Lexical cue
T1 5-16 http://purl.obolibrary.org/obo/GO_0046960 denotes sensitivity
T2 361-373 http://purl.obolibrary.org/obo/GO_0009058 denotes biosynthesis
T3 667-677 http://purl.obolibrary.org/obo/GO_0097503 denotes sialylated
T4 1721-1729 http://purl.obolibrary.org/obo/GO_0097502 denotes mannosyl

GO-CC

Id Subject Object Predicate Lexical cue
T1 58-62 http://purl.obolibrary.org/obo/GO_0019013 denotes core
T2 310-314 http://purl.obolibrary.org/obo/GO_0019013 denotes core
T3 377-381 http://purl.obolibrary.org/obo/GO_0019013 denotes core
T4 581-585 http://purl.obolibrary.org/obo/GO_0019013 denotes core
T5 1062-1066 http://purl.obolibrary.org/obo/GO_0019013 denotes core
T6 1249-1253 http://purl.obolibrary.org/obo/GO_0019013 denotes core
T7 1304-1308 http://purl.obolibrary.org/obo/GO_0019013 denotes core
T8 1374-1378 http://purl.obolibrary.org/obo/GO_0019013 denotes core
T9 1551-1555 http://purl.obolibrary.org/obo/GO_0019013 denotes core
T10 109-113 http://purl.obolibrary.org/obo/GO_0019013 denotes Core

Allie

Id Subject Object Predicate Lexical cue
SS1_20855471_1_0 109-152 expanded denotes Core 2 β1,6-N-acetylglucosaminyltransferase
SS2_20855471_1_0 154-159 abbr denotes C2GnT
AE1_20855471_1_0 SS1_20855471_1_0 SS2_20855471_1_0 abbreviatedTo "Core 2 β1,6-N-acetylglucosaminyltransferase",C2GnT

GlycoBiology-MAT

Id Subject Object Predicate Lexical cue
T1 703-708 http://purl.obolibrary.org/obo/MAT_0000526 denotes colon
T2 710-725 http://purl.obolibrary.org/obo/MAT_0000047 denotes small intestine
T3 716-725 http://purl.obolibrary.org/obo/MAT_0000043 denotes intestine
T4 727-734 http://purl.obolibrary.org/obo/MAT_0000051 denotes stomach
T5 736-742 http://purl.obolibrary.org/obo/MAT_0000119 denotes kidney
T6 744-751 http://purl.obolibrary.org/obo/MAT_0000081 denotes thyroid
T7 752-759 http://purl.obolibrary.org/obo/MAT_0000137 denotes trachea
T8 764-770 http://purl.obolibrary.org/obo/MAT_0000080 denotes thymus
T9 1311-1319 http://purl.obolibrary.org/obo/MAT_0000086 denotes antennae
T10 1338-1345 http://purl.obolibrary.org/obo/MAT_0000051 denotes stomach
T11 1354-1359 http://purl.obolibrary.org/obo/MAT_0000526 denotes colon
T12 1588-1596 http://purl.obolibrary.org/obo/MAT_0000086 denotes antennae
T13 1778-1785 http://purl.obolibrary.org/obo/MAT_0000051 denotes stomach
T14 1889-1894 http://purl.obolibrary.org/obo/MAT_0000526 denotes colon

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-108 Sentence denotes High-sensitivity O-glycomic analysis of mice deficient in core 2 {beta}1,6-N-acetylglucosaminyltransferases.
TextSentencer_T2 109-284 Sentence denotes Core 2 β1,6-N-acetylglucosaminyltransferase (C2GnT), which exists in three isoforms, C2GnT1, C2GnT2 and C2GnT3, is one of the key enzymes in the O-glycan biosynthetic pathway.
TextSentencer_T3 285-409 Sentence denotes These isoenzymes produce core 2 O-glycans and have been correlated with the biosynthesis of core 4 O-glycans and I-branches.
TextSentencer_T4 410-597 Sentence denotes Previously, we have reported mice with single and multiple deficiencies of C2GnT isoenzyme(s) and have evaluated the biological and structural consequences of the loss of core 2 function.
TextSentencer_T5 598-858 Sentence denotes We now present more comprehensive O-glycomic analyses of neutral and sialylated glycans expressed in the colon, small intestine, stomach, kidney, thyroid/trachea and thymus of wild-type, C2GnT2 and C2GnT3 single knockouts and the C2GnT1-3 triple knockout mice.
TextSentencer_T6 859-999 Sentence denotes Very high-quality data have emerged from our mass spectrometry techniques with the capability of detecting O-glycans up to at least 3500 Da.
TextSentencer_T7 1000-1198 Sentence denotes We were able to unambiguously elucidate the types of O-glycan core, branching location and residue linkages, which allowed us to exhaustively characterize structural changes in the knockout tissues.
TextSentencer_T8 1199-1360 Sentence denotes The C2GnT2 knockout mice suffered a major loss of core 2 O-glycans as well as glycans with I-branches on core 1 antennae especially in the stomach and the colon.
TextSentencer_T9 1361-1474 Sentence denotes In contrast, core 2 O-glycans still dominated the O-glycomic profile of most tissues in the C2GnT3 knockout mice.
TextSentencer_T10 1475-1697 Sentence denotes Analysis of the C2GnT triple knockout mice revealed a complete loss of both core 2 O-glycans and branched core 1 antennae, confirming that the three known isoenzymes are entirely responsible for producing these structures.
TextSentencer_T11 1698-1786 Sentence denotes Unexpectedly, O-linked mannosyl glycans are upregulated in the triple deficient stomach.
TextSentencer_T12 1787-1955 Sentence denotes In addition, our studies have revealed an interesting terminal structure detected on O-glycans of the colon tissues that is similar to the RM2 antigen from glycolipids.
T1 0-108 Sentence denotes High-sensitivity O-glycomic analysis of mice deficient in core 2 {beta}1,6-N-acetylglucosaminyltransferases.
T2 109-284 Sentence denotes Core 2 β1,6-N-acetylglucosaminyltransferase (C2GnT), which exists in three isoforms, C2GnT1, C2GnT2 and C2GnT3, is one of the key enzymes in the O-glycan biosynthetic pathway.
T3 285-409 Sentence denotes These isoenzymes produce core 2 O-glycans and have been correlated with the biosynthesis of core 4 O-glycans and I-branches.
T4 410-597 Sentence denotes Previously, we have reported mice with single and multiple deficiencies of C2GnT isoenzyme(s) and have evaluated the biological and structural consequences of the loss of core 2 function.
T5 598-858 Sentence denotes We now present more comprehensive O-glycomic analyses of neutral and sialylated glycans expressed in the colon, small intestine, stomach, kidney, thyroid/trachea and thymus of wild-type, C2GnT2 and C2GnT3 single knockouts and the C2GnT1-3 triple knockout mice.
T6 859-1198 Sentence denotes Very high-quality data have emerged from our mass spectrometry techniques with the capability of detecting O-glycans up to at least 3500 Da. We were able to unambiguously elucidate the types of O-glycan core, branching location and residue linkages, which allowed us to exhaustively characterize structural changes in the knockout tissues.
T7 1199-1360 Sentence denotes The C2GnT2 knockout mice suffered a major loss of core 2 O-glycans as well as glycans with I-branches on core 1 antennae especially in the stomach and the colon.
T8 1361-1474 Sentence denotes In contrast, core 2 O-glycans still dominated the O-glycomic profile of most tissues in the C2GnT3 knockout mice.
T9 1475-1697 Sentence denotes Analysis of the C2GnT triple knockout mice revealed a complete loss of both core 2 O-glycans and branched core 1 antennae, confirming that the three known isoenzymes are entirely responsible for producing these structures.
T10 1698-1786 Sentence denotes Unexpectedly, O-linked mannosyl glycans are upregulated in the triple deficient stomach.
T11 1787-1955 Sentence denotes In addition, our studies have revealed an interesting terminal structure detected on O-glycans of the colon tissues that is similar to the RM2 antigen from glycolipids.
T1 0-108 Sentence denotes High-sensitivity O-glycomic analysis of mice deficient in core 2 {beta}1,6-N-acetylglucosaminyltransferases.
T2 109-284 Sentence denotes Core 2 β1,6-N-acetylglucosaminyltransferase (C2GnT), which exists in three isoforms, C2GnT1, C2GnT2 and C2GnT3, is one of the key enzymes in the O-glycan biosynthetic pathway.
T3 285-409 Sentence denotes These isoenzymes produce core 2 O-glycans and have been correlated with the biosynthesis of core 4 O-glycans and I-branches.
T4 410-597 Sentence denotes Previously, we have reported mice with single and multiple deficiencies of C2GnT isoenzyme(s) and have evaluated the biological and structural consequences of the loss of core 2 function.
T5 598-858 Sentence denotes We now present more comprehensive O-glycomic analyses of neutral and sialylated glycans expressed in the colon, small intestine, stomach, kidney, thyroid/trachea and thymus of wild-type, C2GnT2 and C2GnT3 single knockouts and the C2GnT1-3 triple knockout mice.
T6 859-999 Sentence denotes Very high-quality data have emerged from our mass spectrometry techniques with the capability of detecting O-glycans up to at least 3500 Da.
T7 1000-1198 Sentence denotes We were able to unambiguously elucidate the types of O-glycan core, branching location and residue linkages, which allowed us to exhaustively characterize structural changes in the knockout tissues.
T8 1199-1360 Sentence denotes The C2GnT2 knockout mice suffered a major loss of core 2 O-glycans as well as glycans with I-branches on core 1 antennae especially in the stomach and the colon.
T9 1361-1474 Sentence denotes In contrast, core 2 O-glycans still dominated the O-glycomic profile of most tissues in the C2GnT3 knockout mice.
T10 1475-1697 Sentence denotes Analysis of the C2GnT triple knockout mice revealed a complete loss of both core 2 O-glycans and branched core 1 antennae, confirming that the three known isoenzymes are entirely responsible for producing these structures.
T11 1698-1786 Sentence denotes Unexpectedly, O-linked mannosyl glycans are upregulated in the triple deficient stomach.
T12 1787-1955 Sentence denotes In addition, our studies have revealed an interesting terminal structure detected on O-glycans of the colon tissues that is similar to the RM2 antigen from glycolipids.

GlycoBiology-Epitope

Id Subject Object Predicate Lexical cue
PD-GlycoEpitope-B_T1 1926-1929 http://www.glycoepitope.jp/epitopes/AN0279 denotes RM2

performance-test

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 1190-1197 http://purl.obolibrary.org/obo/UBERON_0000479 denotes tissues
PD-UBERON-AE-B_T2 1438-1445 http://purl.obolibrary.org/obo/UBERON_0000479 denotes tissues
PD-UBERON-AE-B_T3 1895-1902 http://purl.obolibrary.org/obo/UBERON_0000479 denotes tissues
PD-UBERON-AE-B_T4 703-708 http://purl.obolibrary.org/obo/UBERON_0001155 denotes colon
PD-UBERON-AE-B_T5 1354-1359 http://purl.obolibrary.org/obo/UBERON_0001155 denotes colon
PD-UBERON-AE-B_T6 1889-1894 http://purl.obolibrary.org/obo/UBERON_0001155 denotes colon
PD-UBERON-AE-B_T7 736-742 http://purl.obolibrary.org/obo/UBERON_0002113 denotes kidney
PD-UBERON-AE-B_T8 727-734 http://purl.obolibrary.org/obo/UBERON_0000945 denotes stomach
PD-UBERON-AE-B_T9 1338-1345 http://purl.obolibrary.org/obo/UBERON_0000945 denotes stomach
PD-UBERON-AE-B_T10 1778-1785 http://purl.obolibrary.org/obo/UBERON_0000945 denotes stomach
PD-UBERON-AE-B_T11 716-725 http://purl.obolibrary.org/obo/UBERON_0000160 denotes intestine
PD-UBERON-AE-B_T12 1311-1319 http://purl.obolibrary.org/obo/UBERON_0000972 denotes antennae
PD-UBERON-AE-B_T13 1588-1596 http://purl.obolibrary.org/obo/UBERON_0000972 denotes antennae
PD-UBERON-AE-B_T14 710-725 http://purl.obolibrary.org/obo/UBERON_0002108 denotes small intestine
PD-UBERON-AE-B_T15 752-759 http://purl.obolibrary.org/obo/UBERON_0003126 denotes trachea
PD-UBERON-AE-B_T16 764-770 http://purl.obolibrary.org/obo/UBERON_0002370 denotes thymus

GlyCosmos15-Glycan

Id Subject Object Predicate Lexical cue image
T1 58-64 Glycan denotes core 2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G00033MO
T2 109-115 Glycan denotes Core 2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G00033MO
T3 310-316 Glycan denotes core 2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G00033MO
T4 377-383 Glycan denotes core 4 https://api.glycosmos.org/wurcs2image/latest/png/binary/G00037MO
T5 581-587 Glycan denotes core 2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G00033MO
T6 1249-1255 Glycan denotes core 2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G00033MO
T7 1304-1310 Glycan denotes core 1 https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO
T8 1374-1380 Glycan denotes core 2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G00033MO
T9 1551-1557 Glycan denotes core 2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G00033MO
T10 1581-1587 Glycan denotes core 1 https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO

Glycan-GlyCosmos

Id Subject Object Predicate Lexical cue image
T1 58-64 Glycan denotes core 2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G00033MO
T2 310-316 Glycan denotes core 2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G00033MO
T3 377-383 Glycan denotes core 4 https://api.glycosmos.org/wurcs2image/latest/png/binary/G00037MO
T4 581-587 Glycan denotes core 2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G00033MO
T5 1249-1255 Glycan denotes core 2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G00033MO
T6 1304-1310 Glycan denotes core 1 https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO
T7 1374-1380 Glycan denotes core 2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G00033MO
T8 1551-1557 Glycan denotes core 2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G00033MO
T9 1581-1587 Glycan denotes core 1 https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO

GlyCosmos15-Sentences

Id Subject Object Predicate Lexical cue
T1 0-108 Sentence denotes High-sensitivity O-glycomic analysis of mice deficient in core 2 {beta}1,6-N-acetylglucosaminyltransferases.
T2 109-284 Sentence denotes Core 2 β1,6-N-acetylglucosaminyltransferase (C2GnT), which exists in three isoforms, C2GnT1, C2GnT2 and C2GnT3, is one of the key enzymes in the O-glycan biosynthetic pathway.
T3 285-409 Sentence denotes These isoenzymes produce core 2 O-glycans and have been correlated with the biosynthesis of core 4 O-glycans and I-branches.
T4 410-597 Sentence denotes Previously, we have reported mice with single and multiple deficiencies of C2GnT isoenzyme(s) and have evaluated the biological and structural consequences of the loss of core 2 function.
T5 598-858 Sentence denotes We now present more comprehensive O-glycomic analyses of neutral and sialylated glycans expressed in the colon, small intestine, stomach, kidney, thyroid/trachea and thymus of wild-type, C2GnT2 and C2GnT3 single knockouts and the C2GnT1-3 triple knockout mice.
T6 859-1198 Sentence denotes Very high-quality data have emerged from our mass spectrometry techniques with the capability of detecting O-glycans up to at least 3500 Da. We were able to unambiguously elucidate the types of O-glycan core, branching location and residue linkages, which allowed us to exhaustively characterize structural changes in the knockout tissues.
T7 1199-1360 Sentence denotes The C2GnT2 knockout mice suffered a major loss of core 2 O-glycans as well as glycans with I-branches on core 1 antennae especially in the stomach and the colon.
T8 1361-1474 Sentence denotes In contrast, core 2 O-glycans still dominated the O-glycomic profile of most tissues in the C2GnT3 knockout mice.
T9 1475-1697 Sentence denotes Analysis of the C2GnT triple knockout mice revealed a complete loss of both core 2 O-glycans and branched core 1 antennae, confirming that the three known isoenzymes are entirely responsible for producing these structures.
T10 1698-1786 Sentence denotes Unexpectedly, O-linked mannosyl glycans are upregulated in the triple deficient stomach.
T11 1787-1955 Sentence denotes In addition, our studies have revealed an interesting terminal structure detected on O-glycans of the colon tissues that is similar to the RM2 antigen from glycolipids.

GlyCosmos15-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 703-708 Body_part denotes colon http://purl.obolibrary.org/obo/UBERON_0001155
T2 710-725 Body_part denotes small intestine http://purl.obolibrary.org/obo/UBERON_0002108
T3 727-734 Body_part denotes stomach http://purl.obolibrary.org/obo/UBERON_0000945
T4 736-742 Body_part denotes kidney http://purl.obolibrary.org/obo/UBERON_0002113
T5 744-751 Body_part denotes thyroid http://purl.obolibrary.org/obo/UBERON_0002046
T6 752-759 Body_part denotes trachea http://purl.obolibrary.org/obo/UBERON_0003126|http://purl.obolibrary.org/obo/UBERON_0003127|http://purl.obolibrary.org/obo/UBERON_6005043
T9 764-770 Body_part denotes thymus http://purl.obolibrary.org/obo/UBERON_0002370
T10 1338-1345 Body_part denotes stomach http://purl.obolibrary.org/obo/UBERON_0000945
T11 1354-1359 Body_part denotes colon http://purl.obolibrary.org/obo/UBERON_0001155
T12 1778-1785 Body_part denotes stomach http://purl.obolibrary.org/obo/UBERON_0000945
T13 1889-1894 Body_part denotes colon http://purl.obolibrary.org/obo/UBERON_0001155

GlyCosmos15-NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 40-44 OrganismTaxon denotes mice 10088
T2 439-443 OrganismTaxon denotes mice 10088
T3 764-770 OrganismTaxon denotes thymus 49990
T4 853-857 OrganismTaxon denotes mice 10088
T5 1219-1223 OrganismTaxon denotes mice 10088
T6 1469-1473 OrganismTaxon denotes mice 10088
T7 1513-1517 OrganismTaxon denotes mice 10088

GlyCosmos15-FMA

Id Subject Object Predicate Lexical cue db_id
T1 527-552 Body_part denotes biological and structural FMA:305751
T2 703-708 Body_part denotes colon FMA:14543
T3 710-725 Body_part denotes small intestine FMA:7200
T4 727-734 Body_part denotes stomach FMA:7148
T5 736-742 Body_part denotes kidney FMA:7203
T6 752-759 Body_part denotes trachea FMA:7394
T7 764-770 Body_part denotes thymus FMA:9607
T8 1190-1197 Body_part denotes tissues FMA:9637
T9 1338-1345 Body_part denotes stomach FMA:7148
T10 1354-1359 Body_part denotes colon FMA:14543
T11 1438-1445 Body_part denotes tissues FMA:9637
T12 1778-1785 Body_part denotes stomach FMA:7148
T13 1889-1894 Body_part denotes colon FMA:14543
T14 1895-1902 Body_part denotes tissues FMA:9637

GlyCosmos15-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 703-708 Body_part denotes colon http://purl.obolibrary.org/obo/MAT_0000526
T2 710-725 Body_part denotes small intestine http://purl.obolibrary.org/obo/MAT_0000047
T3 727-734 Body_part denotes stomach http://purl.obolibrary.org/obo/MAT_0000051
T4 736-742 Body_part denotes kidney http://purl.obolibrary.org/obo/MAT_0000119
T5 744-751 Body_part denotes thyroid http://purl.obolibrary.org/obo/MAT_0000081
T6 752-759 Body_part denotes trachea http://purl.obolibrary.org/obo/MAT_0000137
T7 764-770 Body_part denotes thymus http://purl.obolibrary.org/obo/MAT_0000080
T8 1311-1319 Body_part denotes antennae http://purl.obolibrary.org/obo/MAT_0000086
T9 1338-1345 Body_part denotes stomach http://purl.obolibrary.org/obo/MAT_0000051
T10 1354-1359 Body_part denotes colon http://purl.obolibrary.org/obo/MAT_0000526
T11 1588-1596 Body_part denotes antennae http://purl.obolibrary.org/obo/MAT_0000086
T12 1778-1785 Body_part denotes stomach http://purl.obolibrary.org/obo/MAT_0000051
T13 1889-1894 Body_part denotes colon http://purl.obolibrary.org/obo/MAT_0000526

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 40-44 OrganismTaxon denotes mice 10088
T2 439-443 OrganismTaxon denotes mice 10088
T3 752-759 OrganismTaxon denotes trachea 988164
T4 764-770 OrganismTaxon denotes thymus 49990
T5 853-857 OrganismTaxon denotes mice 10088
T6 1219-1223 OrganismTaxon denotes mice 10088
T7 1469-1473 OrganismTaxon denotes mice 10088
T8 1513-1517 OrganismTaxon denotes mice 10088

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 703-708 Body_part denotes colon http://purl.obolibrary.org/obo/MAT_0000526
T2 710-725 Body_part denotes small intestine http://purl.obolibrary.org/obo/MAT_0000047
T3 727-734 Body_part denotes stomach http://purl.obolibrary.org/obo/MAT_0000051
T4 736-742 Body_part denotes kidney http://purl.obolibrary.org/obo/MAT_0000119
T5 744-751 Body_part denotes thyroid http://purl.obolibrary.org/obo/MAT_0000081
T6 752-759 Body_part denotes trachea http://purl.obolibrary.org/obo/MAT_0000137
T7 764-770 Body_part denotes thymus http://purl.obolibrary.org/obo/MAT_0000080
T8 1311-1319 Body_part denotes antennae http://purl.obolibrary.org/obo/MAT_0000086
T9 1338-1345 Body_part denotes stomach http://purl.obolibrary.org/obo/MAT_0000051
T10 1354-1359 Body_part denotes colon http://purl.obolibrary.org/obo/MAT_0000526
T11 1588-1596 Body_part denotes antennae http://purl.obolibrary.org/obo/MAT_0000086
T12 1778-1785 Body_part denotes stomach http://purl.obolibrary.org/obo/MAT_0000051
T13 1889-1894 Body_part denotes colon http://purl.obolibrary.org/obo/MAT_0000526

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 703-708 Body_part denotes colon http://purl.obolibrary.org/obo/UBERON_0001155
T2 710-725 Body_part denotes small intestine http://purl.obolibrary.org/obo/UBERON_0002108
T3 727-734 Body_part denotes stomach http://purl.obolibrary.org/obo/UBERON_0000945
T4 736-742 Body_part denotes kidney http://purl.obolibrary.org/obo/UBERON_0002113
T5 744-751 Body_part denotes thyroid http://purl.obolibrary.org/obo/UBERON_0002046
T6 752-759 Body_part denotes trachea http://purl.obolibrary.org/obo/UBERON_0003126|http://purl.obolibrary.org/obo/UBERON_0003127|http://purl.obolibrary.org/obo/UBERON_6005043
T9 764-770 Body_part denotes thymus http://purl.obolibrary.org/obo/UBERON_0002370
T10 1338-1345 Body_part denotes stomach http://purl.obolibrary.org/obo/UBERON_0000945
T11 1354-1359 Body_part denotes colon http://purl.obolibrary.org/obo/UBERON_0001155
T12 1778-1785 Body_part denotes stomach http://purl.obolibrary.org/obo/UBERON_0000945
T13 1889-1894 Body_part denotes colon http://purl.obolibrary.org/obo/UBERON_0001155