PubMed:20705401
Annnotations
LitCoin-entities-OrganismTaxon-PD
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 434-438 | OrganismTaxon | denotes | rats | NCBItxid:10118|NCBItxid:10116|NCBItxid:10114 |
| T4 | 663-667 | OrganismTaxon | denotes | rats | NCBItxid:10118|NCBItxid:10116|NCBItxid:10114 |
LitCoin-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-104 | Sentence | denotes | Serotonin 6 receptor gene is associated with methamphetamine-induced psychosis in a Japanese population. |
| T2 | 105-116 | Sentence | denotes | BACKGROUND: |
| T3 | 117-250 | Sentence | denotes | Altered serotonergic neural transmission is hypothesized to be a susceptibility factor for psychotic disorders such as schizophrenia. |
| T4 | 251-506 | Sentence | denotes | The serotonin 6 (5-HT6) receptor is therapeutically targeted by several second generation antipsychotics, such as clozapine and olanzapine, and d-amphetamine-induced hyperactivity in rats is corrected with the use of a selective 5-HT6 receptor antagonist. |
| T5 | 507-668 | Sentence | denotes | In addition, the disrupted prepulse inhibition induced by d-amphetamine or phencyclidine was restored by 5-HT6 receptor antagonist in an animal study using rats. |
| T6 | 669-876 | Sentence | denotes | These animal models were considered to reflect the positive symptoms of schizophrenia, and the above evidence suggests that altered 5-HT6 receptors are involved in the pathophysiology of psychotic disorders. |
| T7 | 877-986 | Sentence | denotes | The symptoms of methamphetamine (METH)-induced psychosis are similar to those of paranoid type schizophrenia. |
| T8 | 987-1095 | Sentence | denotes | Therefore, we conducted an analysis of the association of the 5-HT6 gene (HTR6) with METH-induced psychosis. |
| T9 | 1096-1103 | Sentence | denotes | METHOD: |
| T10 | 1104-1338 | Sentence | denotes | Using five tagging SNPs (rs6693503, rs1805054, rs4912138, rs3790757 and rs9659997), we conducted a genetic association analysis of case-control samples (197 METH-induced psychosis patients and 337 controls) in the Japanese population. |
| T11 | 1339-1448 | Sentence | denotes | The age and sex of the control subjects did not differ from those of the methamphetamine dependence patients. |
| T12 | 1449-1557 | Sentence | denotes | RESULTS: rs6693503 was associated with METH-induced psychosis patients in the allele/genotype-wise analysis. |
| T13 | 1558-1634 | Sentence | denotes | Moreover, this association remained significant after Bonferroni correction. |
| T14 | 1635-1853 | Sentence | denotes | In the haplotype-wise analysis, we detected an association between two markers (rs6693503 and rs1805054) and three markers (rs6693503, rs1805054 and rs4912138) in HTR6 and METH-induced psychosis patients, respectively. |
| T15 | 1854-1974 | Sentence | denotes | CONCLUSION: HTR6 may play an important role in the pathophysiology of METH-induced psychosis in the Japanese population. |
LitCoin-entities
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| 7790 | 0-20 | GeneOrGeneProduct | denotes | Serotonin 6 receptor | NCBIGene:3362 |
| 7791 | 45-60 | ChemicalEntity | denotes | methamphetamine | MESH:D008694 |
| 7792 | 69-78 | DiseaseOrPhenotypicFeature | denotes | psychosis | MESH:D011605 |
| 7793 | 208-227 | DiseaseOrPhenotypicFeature | denotes | psychotic disorders | MESH:D011605 |
| 7794 | 236-249 | DiseaseOrPhenotypicFeature | denotes | schizophrenia | MESH:D012559 |
| 7795 | 255-283 | GeneOrGeneProduct | denotes | serotonin 6 (5-HT6) receptor | NCBIGene:3362 |
| 7796 | 341-355 | ChemicalEntity | denotes | antipsychotics | MESH:D014150 |
| 7797 | 365-374 | ChemicalEntity | denotes | clozapine | MESH:D003024 |
| 7798 | 379-389 | ChemicalEntity | denotes | olanzapine | MESH:D000077152 |
| 7799 | 395-408 | ChemicalEntity | denotes | d-amphetamine | MESH:D003913 |
| 7800 | 417-430 | DiseaseOrPhenotypicFeature | denotes | hyperactivity | MESH:D006948 |
| 7801 | 434-438 | OrganismTaxon | denotes | rats | NCBITaxon:10116 |
| 7802 | 480-505 | ChemicalEntity | denotes | 5-HT6 receptor antagonist | MESH:D012702 |
| 7803 | 565-578 | ChemicalEntity | denotes | d-amphetamine | MESH:D003913 |
| 7804 | 582-595 | ChemicalEntity | denotes | phencyclidine | MESH:D010622 |
| 7805 | 612-637 | ChemicalEntity | denotes | 5-HT6 receptor antagonist | MESH:D012702 |
| 7806 | 663-667 | OrganismTaxon | denotes | rats | NCBITaxon:10116 |
| 7807 | 741-754 | DiseaseOrPhenotypicFeature | denotes | schizophrenia | MESH:D012559 |
| 7808 | 801-816 | GeneOrGeneProduct | denotes | 5-HT6 receptors | NCBIGene:3362 |
| 7809 | 856-875 | DiseaseOrPhenotypicFeature | denotes | psychotic disorders | MESH:D011605 |
| 7810 | 893-908 | ChemicalEntity | denotes | methamphetamine | MESH:D008694 |
| 7811 | 910-914 | ChemicalEntity | denotes | METH | MESH:D008694 |
| 7812 | 924-933 | DiseaseOrPhenotypicFeature | denotes | psychosis | MESH:D011605 |
| 7813 | 958-985 | DiseaseOrPhenotypicFeature | denotes | paranoid type schizophrenia | MESH:D012563 |
| 7814 | 1049-1054 | GeneOrGeneProduct | denotes | 5-HT6 | NCBIGene:3362 |
| 7815 | 1061-1065 | GeneOrGeneProduct | denotes | HTR6 | NCBIGene:3362 |
| 7816 | 1072-1076 | ChemicalEntity | denotes | METH | MESH:D008694 |
| 7817 | 1085-1094 | DiseaseOrPhenotypicFeature | denotes | psychosis | MESH:D011605 |
| 7818 | 1129-1138 | SequenceVariant | denotes | rs6693503 | DBSNP:rs6693503 |
| 7819 | 1140-1149 | SequenceVariant | denotes | rs1805054 | DBSNP:rs1805054 |
| 7820 | 1151-1160 | SequenceVariant | denotes | rs4912138 | DBSNP:rs4912138 |
| 7821 | 1162-1171 | SequenceVariant | denotes | rs3790757 | DBSNP:rs3790757 |
| 7822 | 1176-1185 | SequenceVariant | denotes | rs9659997 | DBSNP:rs9659997 |
| 7823 | 1261-1265 | ChemicalEntity | denotes | METH | MESH:D008694 |
| 7824 | 1274-1283 | DiseaseOrPhenotypicFeature | denotes | psychosis | MESH:D011605 |
| 7825 | 1284-1292 | OrganismTaxon | denotes | patients | NCBITaxon:9606 |
| 7826 | 1412-1427 | ChemicalEntity | denotes | methamphetamine | MESH:D008694 |
| 7827 | 1439-1447 | OrganismTaxon | denotes | patients | NCBITaxon:9606 |
| 7828 | 1458-1467 | SequenceVariant | denotes | rs6693503 | DBSNP:rs6693503 |
| 7829 | 1488-1492 | ChemicalEntity | denotes | METH | MESH:D008694 |
| 7830 | 1501-1510 | DiseaseOrPhenotypicFeature | denotes | psychosis | MESH:D011605 |
| 7831 | 1511-1519 | OrganismTaxon | denotes | patients | NCBITaxon:9606 |
| 7832 | 1715-1724 | SequenceVariant | denotes | rs6693503 | DBSNP:rs6693503 |
| 7833 | 1729-1738 | SequenceVariant | denotes | rs1805054 | DBSNP:rs1805054 |
| 7834 | 1759-1768 | SequenceVariant | denotes | rs6693503 | DBSNP:rs6693503 |
| 7835 | 1770-1779 | SequenceVariant | denotes | rs1805054 | DBSNP:rs1805054 |
| 7836 | 1784-1793 | SequenceVariant | denotes | rs4912138 | DBSNP:rs4912138 |
| 7837 | 1798-1802 | GeneOrGeneProduct | denotes | HTR6 | NCBIGene:3362 |
| 7838 | 1807-1811 | ChemicalEntity | denotes | METH | MESH:D008694 |
| 7839 | 1820-1829 | DiseaseOrPhenotypicFeature | denotes | psychosis | MESH:D011605 |
| 7840 | 1830-1838 | OrganismTaxon | denotes | patients | NCBITaxon:9606 |
| 7841 | 1866-1870 | GeneOrGeneProduct | denotes | HTR6 | NCBIGene:3362 |
| 7842 | 1924-1928 | ChemicalEntity | denotes | METH | MESH:D008694 |
| 7843 | 1937-1946 | DiseaseOrPhenotypicFeature | denotes | psychosis | MESH:D011605 |
LitCoin_Mondo
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 45-78 | DiseaseOrPhenotypicFeature | denotes | methamphetamine-induced psychosis | 0005465 |
| T2 | 208-227 | DiseaseOrPhenotypicFeature | denotes | psychotic disorders | 0005485 |
| T3 | 236-249 | DiseaseOrPhenotypicFeature | denotes | schizophrenia | 0005090 |
| T4 | 741-754 | DiseaseOrPhenotypicFeature | denotes | schizophrenia | 0005090 |
| T5 | 856-875 | DiseaseOrPhenotypicFeature | denotes | psychotic disorders | 0005485 |
| T6 | 972-985 | DiseaseOrPhenotypicFeature | denotes | schizophrenia | 0005090 |
LitCoin-SeqVar
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 1129-1138 | SequenceVariant | denotes | rs6693503 |
| T2 | 1140-1149 | SequenceVariant | denotes | rs1805054 |
| T3 | 1151-1160 | SequenceVariant | denotes | rs4912138 |
| T4 | 1162-1171 | SequenceVariant | denotes | rs3790757 |
| T5 | 1176-1185 | SequenceVariant | denotes | rs9659997 |
| T6 | 1458-1467 | SequenceVariant | denotes | rs6693503 |
| T7 | 1715-1724 | SequenceVariant | denotes | rs6693503 |
| T8 | 1729-1738 | SequenceVariant | denotes | rs1805054 |
| T9 | 1759-1768 | SequenceVariant | denotes | rs6693503 |
| T10 | 1770-1779 | SequenceVariant | denotes | rs1805054 |
| T11 | 1784-1793 | SequenceVariant | denotes | rs4912138 |
LitCoin-GeneOrGeneProduct-v0
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 12-20 | GeneOrGeneProduct | denotes | receptor |
| T2 | 61-68 | GeneOrGeneProduct | denotes | induced |
| T3 | 79-83 | GeneOrGeneProduct | denotes | in a |
| T4 | 138-144 | GeneOrGeneProduct | denotes | neural |
| T5 | 197-203 | GeneOrGeneProduct | denotes | factor |
| T6 | 268-273 | GeneOrGeneProduct | denotes | 5-HT6 |
| T7 | 275-283 | GeneOrGeneProduct | denotes | receptor |
| T8 | 409-416 | GeneOrGeneProduct | denotes | induced |
| T9 | 480-485 | GeneOrGeneProduct | denotes | 5-HT6 |
| T10 | 486-494 | GeneOrGeneProduct | denotes | receptor |
| T11 | 495-505 | GeneOrGeneProduct | denotes | antagonist |
| T12 | 524-533 | GeneOrGeneProduct | denotes | disrupted |
| T13 | 554-561 | GeneOrGeneProduct | denotes | induced |
| T14 | 612-617 | GeneOrGeneProduct | denotes | 5-HT6 |
| T15 | 618-626 | GeneOrGeneProduct | denotes | receptor |
| T16 | 627-637 | GeneOrGeneProduct | denotes | antagonist |
| T17 | 801-806 | GeneOrGeneProduct | denotes | 5-HT6 |
| T18 | 807-816 | GeneOrGeneProduct | denotes | receptors |
| T19 | 910-914 | GeneOrGeneProduct | denotes | METH |
| T20 | 916-923 | GeneOrGeneProduct | denotes | induced |
| T21 | 938-945 | GeneOrGeneProduct | denotes | similar |
| T22 | 1049-1054 | GeneOrGeneProduct | denotes | 5-HT6 |
| T23 | 1061-1065 | GeneOrGeneProduct | denotes | HTR6 |
| T24 | 1072-1076 | GeneOrGeneProduct | denotes | METH |
| T25 | 1077-1084 | GeneOrGeneProduct | denotes | induced |
| T26 | 1096-1102 | GeneOrGeneProduct | denotes | METHOD |
| T27 | 1235-1239 | GeneOrGeneProduct | denotes | case |
| T28 | 1261-1265 | GeneOrGeneProduct | denotes | METH |
| T29 | 1266-1273 | GeneOrGeneProduct | denotes | induced |
| T30 | 1488-1492 | GeneOrGeneProduct | denotes | METH |
| T31 | 1493-1500 | GeneOrGeneProduct | denotes | induced |
| T32 | 1543-1547 | GeneOrGeneProduct | denotes | wise |
| T33 | 1652-1656 | GeneOrGeneProduct | denotes | wise |
| T34 | 1798-1802 | GeneOrGeneProduct | denotes | HTR6 |
| T35 | 1807-1811 | GeneOrGeneProduct | denotes | METH |
| T36 | 1812-1819 | GeneOrGeneProduct | denotes | induced |
| T37 | 1866-1870 | GeneOrGeneProduct | denotes | HTR6 |
| T38 | 1924-1928 | GeneOrGeneProduct | denotes | METH |
| T39 | 1929-1936 | GeneOrGeneProduct | denotes | induced |
LitCoin-GeneOrGeneProduct-v2
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 12-20 | GeneOrGeneProduct | denotes | receptor |
| T2 | 197-203 | GeneOrGeneProduct | denotes | factor |
| T3 | 268-273 | GeneOrGeneProduct | denotes | 5-HT6 |
| T4 | 275-283 | GeneOrGeneProduct | denotes | receptor |
| T5 | 480-485 | GeneOrGeneProduct | denotes | 5-HT6 |
| T6 | 486-494 | GeneOrGeneProduct | denotes | receptor |
| T7 | 524-533 | GeneOrGeneProduct | denotes | disrupted |
| T8 | 612-617 | GeneOrGeneProduct | denotes | 5-HT6 |
| T9 | 618-626 | GeneOrGeneProduct | denotes | receptor |
| T10 | 801-806 | GeneOrGeneProduct | denotes | 5-HT6 |
| T11 | 910-914 | GeneOrGeneProduct | denotes | METH |
| T12 | 938-945 | GeneOrGeneProduct | denotes | similar |
| T13 | 1049-1054 | GeneOrGeneProduct | denotes | 5-HT6 |
| T14 | 1061-1065 | GeneOrGeneProduct | denotes | HTR6 |
| T15 | 1072-1076 | GeneOrGeneProduct | denotes | METH |
| T16 | 1261-1265 | GeneOrGeneProduct | denotes | METH |
| T17 | 1488-1492 | GeneOrGeneProduct | denotes | METH |
| T18 | 1543-1547 | GeneOrGeneProduct | denotes | wise |
| T19 | 1652-1656 | GeneOrGeneProduct | denotes | wise |
| T20 | 1798-1802 | GeneOrGeneProduct | denotes | HTR6 |
| T21 | 1807-1811 | GeneOrGeneProduct | denotes | METH |
| T22 | 1866-1870 | GeneOrGeneProduct | denotes | HTR6 |
| T23 | 1924-1928 | GeneOrGeneProduct | denotes | METH |
LitCoin-Disease-MeSH
| Id | Subject | Object | Predicate | Lexical cue | originalLabel |
|---|---|---|---|---|---|
| T1 | 69-78 | DiseaseOrPhenotypicFeature | denotes | psychosis | D011618 |
| T2 | 208-227 | DiseaseOrPhenotypicFeature | denotes | psychotic disorders | D011618 |
| T3 | 236-249 | DiseaseOrPhenotypicFeature | denotes | schizophrenia | D012559 |
| T4 | 417-430 | DiseaseOrPhenotypicFeature | denotes | hyperactivity | DISEASE |
| T5 | 741-754 | DiseaseOrPhenotypicFeature | denotes | schizophrenia | D012559 |
| T6 | 856-875 | DiseaseOrPhenotypicFeature | denotes | psychotic disorders | D011618 |
| T7 | 924-933 | DiseaseOrPhenotypicFeature | denotes | psychosis | D011618 |
| T8 | 972-985 | DiseaseOrPhenotypicFeature | denotes | schizophrenia | D012559 |
| T9 | 1085-1094 | DiseaseOrPhenotypicFeature | denotes | psychosis | D011618 |
| T10 | 1274-1283 | DiseaseOrPhenotypicFeature | denotes | psychosis | D011618 |
| T11 | 1501-1510 | DiseaseOrPhenotypicFeature | denotes | psychosis | D011618 |
| T12 | 1820-1829 | DiseaseOrPhenotypicFeature | denotes | psychosis | D011618 |
| T13 | 1937-1946 | DiseaseOrPhenotypicFeature | denotes | psychosis | D011618 |
LitCoin-GeneOrGeneProduct-v3
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 268-273 | GeneOrGeneProduct | denotes | 5-HT6 |
| T2 | 480-485 | GeneOrGeneProduct | denotes | 5-HT6 |
| T3 | 612-617 | GeneOrGeneProduct | denotes | 5-HT6 |
| T4 | 801-806 | GeneOrGeneProduct | denotes | 5-HT6 |
| T5 | 1049-1054 | GeneOrGeneProduct | denotes | 5-HT6 |
| T6 | 1061-1065 | GeneOrGeneProduct | denotes | HTR6 |
| T7 | 1543-1547 | GeneOrGeneProduct | denotes | wise |
| T8 | 1652-1656 | GeneOrGeneProduct | denotes | wise |
| T9 | 1798-1802 | GeneOrGeneProduct | denotes | HTR6 |
| T10 | 1866-1870 | GeneOrGeneProduct | denotes | HTR6 |
LitCoin_Mondo_095
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 45-78 | DiseaseOrPhenotypicFeature | denotes | methamphetamine-induced psychosis | 0005465 |
| T2 | 208-227 | DiseaseOrPhenotypicFeature | denotes | psychotic disorders | 0005485 |
| T3 | 236-249 | DiseaseOrPhenotypicFeature | denotes | schizophrenia | 0005090 |
| T4 | 741-754 | DiseaseOrPhenotypicFeature | denotes | schizophrenia | 0005090 |
| T5 | 856-875 | DiseaseOrPhenotypicFeature | denotes | psychotic disorders | 0005485 |
| T6 | 924-933 | DiseaseOrPhenotypicFeature | denotes | psychosis | 0005485 |
| T7 | 958-985 | DiseaseOrPhenotypicFeature | denotes | paranoid type schizophrenia | 0001484 |
| T8 | 1085-1094 | DiseaseOrPhenotypicFeature | denotes | psychosis | 0005485 |
| T9 | 1274-1283 | DiseaseOrPhenotypicFeature | denotes | psychosis | 0005485 |
| T10 | 1428-1438 | DiseaseOrPhenotypicFeature | denotes | dependence | 0004938 |
| T11 | 1501-1510 | DiseaseOrPhenotypicFeature | denotes | psychosis | 0005485 |
| T12 | 1820-1829 | DiseaseOrPhenotypicFeature | denotes | psychosis | 0005485 |
| T13 | 1937-1946 | DiseaseOrPhenotypicFeature | denotes | psychosis | 0005485 |
LitCoin-MeSH-Disease-2
| Id | Subject | Object | Predicate | Lexical cue | ID: |
|---|---|---|---|---|---|
| T1 | 69-78 | DiseaseOrPhenotypicFeature | denotes | psychosis | D011618 |
| T2 | 208-227 | DiseaseOrPhenotypicFeature | denotes | psychotic disorders | D011618 |
| T3 | 236-249 | DiseaseOrPhenotypicFeature | denotes | schizophrenia | D012559 |
| T4 | 417-430 | DiseaseOrPhenotypicFeature | denotes | hyperactivity | DISEASE |
| T5 | 741-754 | DiseaseOrPhenotypicFeature | denotes | schizophrenia | D012559 |
| T6 | 856-875 | DiseaseOrPhenotypicFeature | denotes | psychotic disorders | D011618 |
| T7 | 924-933 | DiseaseOrPhenotypicFeature | denotes | psychosis | D011618 |
| T8 | 972-985 | DiseaseOrPhenotypicFeature | denotes | schizophrenia | D012559 |
| T9 | 1085-1094 | DiseaseOrPhenotypicFeature | denotes | psychosis | D011618 |
| T10 | 1274-1283 | DiseaseOrPhenotypicFeature | denotes | psychosis | D011618 |
| T11 | 1501-1510 | DiseaseOrPhenotypicFeature | denotes | psychosis | D011618 |
| T12 | 1820-1829 | DiseaseOrPhenotypicFeature | denotes | psychosis | D011618 |
| T13 | 1937-1946 | DiseaseOrPhenotypicFeature | denotes | psychosis | D011618 |
LitCoin-MONDO_bioort2019
| Id | Subject | Object | Predicate | Lexical cue | #label |
|---|---|---|---|---|---|
| T1 | 69-78 | DiseaseOrPhenotypicFeature | denotes | psychosis | D011618 |
| T2 | 208-227 | DiseaseOrPhenotypicFeature | denotes | psychotic disorders | D011618 |
| T3 | 236-249 | DiseaseOrPhenotypicFeature | denotes | schizophrenia | D012559 |
| T4 | 417-430 | DiseaseOrPhenotypicFeature | denotes | hyperactivity | DISEASE |
| T5 | 741-754 | DiseaseOrPhenotypicFeature | denotes | schizophrenia | D012559 |
| T6 | 856-875 | DiseaseOrPhenotypicFeature | denotes | psychotic disorders | D011618 |
| T7 | 924-933 | DiseaseOrPhenotypicFeature | denotes | psychosis | D011618 |
| T8 | 972-985 | DiseaseOrPhenotypicFeature | denotes | schizophrenia | D012559 |
| T9 | 1085-1094 | DiseaseOrPhenotypicFeature | denotes | psychosis | D011618 |
| T10 | 1274-1283 | DiseaseOrPhenotypicFeature | denotes | psychosis | D011618 |
| T11 | 1501-1510 | DiseaseOrPhenotypicFeature | denotes | psychosis | D011618 |
| T12 | 1820-1829 | DiseaseOrPhenotypicFeature | denotes | psychosis | D011618 |
| T13 | 1937-1946 | DiseaseOrPhenotypicFeature | denotes | psychosis | D011618 |
LitCoin-NCBITaxon-2
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 434-438 | OrganismTaxon | denotes | rats |
| T2 | 663-667 | OrganismTaxon | denotes | rats |
| T3 | 1284-1292 | OrganismTaxon | denotes | patients |
| T4 | 1439-1447 | OrganismTaxon | denotes | patients |
| T5 | 1511-1519 | OrganismTaxon | denotes | patients |
| T6 | 1830-1838 | OrganismTaxon | denotes | patients |
LitCoin-Chemical-MeSH-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | ID: |
|---|---|---|---|---|---|
| T1 | 0-9 | ChemicalEntity | denotes | Serotonin | http://purl.obolibrary.org/obo/CHEBI_28790 |
| T2 | 45-60 | ChemicalEntity | denotes | methamphetamine | D008694|http://purl.obolibrary.org/obo/CHEBI_6809 |
| T4 | 255-264 | ChemicalEntity | denotes | serotonin | D012701|http://purl.obolibrary.org/obo/CHEBI_350546|http://purl.obolibrary.org/obo/CHEBI_28790 |
| T7 | 365-374 | ChemicalEntity | denotes | clozapine | D003024|http://purl.obolibrary.org/obo/CHEBI_3766 |
| T9 | 379-389 | ChemicalEntity | denotes | olanzapine | D000077152|http://purl.obolibrary.org/obo/CHEBI_7735 |
| T11 | 395-408 | ChemicalEntity | denotes | d-amphetamine | http://purl.obolibrary.org/obo/CHEBI_4469 |
| T12 | 480-505 | ChemicalEntity | denotes | 5-HT6 receptor antagonist | ChemicalEntity |
| T13 | 565-578 | ChemicalEntity | denotes | d-amphetamine | http://purl.obolibrary.org/obo/CHEBI_4469 |
| T14 | 582-595 | ChemicalEntity | denotes | phencyclidine | D010622|http://purl.obolibrary.org/obo/CHEBI_8058 |
| T16 | 612-637 | ChemicalEntity | denotes | 5-HT6 receptor antagonist | ChemicalEntity |
| T17 | 893-908 | ChemicalEntity | denotes | methamphetamine | D008694|http://purl.obolibrary.org/obo/CHEBI_6809 |
| T19 | 910-914 | ChemicalEntity | denotes | METH | D008694 |
| T20 | 1072-1076 | ChemicalEntity | denotes | METH | D008694 |
| T21 | 1261-1265 | ChemicalEntity | denotes | METH | D008694 |
| T22 | 1412-1427 | ChemicalEntity | denotes | methamphetamine | D008694|http://purl.obolibrary.org/obo/CHEBI_6809 |
| T24 | 1488-1492 | ChemicalEntity | denotes | METH | D008694 |
| T25 | 1807-1811 | ChemicalEntity | denotes | METH | D008694 |
| T26 | 1924-1928 | ChemicalEntity | denotes | METH | D008694 |
LitCoin-training-merged
| Id | Subject | Object | Predicate | Lexical cue | #label | ID: |
|---|---|---|---|---|---|---|
| T26 | 1924-1928 | ChemicalEntity | denotes | METH | D008694 | |
| T25 | 1807-1811 | ChemicalEntity | denotes | METH | D008694 | |
| T24 | 1488-1492 | ChemicalEntity | denotes | METH | D008694 | |
| T22 | 1412-1427 | ChemicalEntity | denotes | methamphetamine | http://purl.obolibrary.org/obo/CHEBI_6809|D008694 | |
| T21 | 1261-1265 | ChemicalEntity | denotes | METH | D008694 | |
| T20 | 1072-1076 | ChemicalEntity | denotes | METH | D008694 | |
| T19 | 910-914 | ChemicalEntity | denotes | METH | D008694 | |
| T17 | 893-908 | ChemicalEntity | denotes | methamphetamine | http://purl.obolibrary.org/obo/CHEBI_6809|D008694 | |
| T16 | 612-637 | ChemicalEntity | denotes | 5-HT6 receptor antagonist | ChemicalEntity | |
| T14 | 582-595 | ChemicalEntity | denotes | phencyclidine | http://purl.obolibrary.org/obo/CHEBI_8058|D010622 | |
| T13 | 565-578 | ChemicalEntity | denotes | d-amphetamine | http://purl.obolibrary.org/obo/CHEBI_4469 | |
| T12 | 480-505 | ChemicalEntity | denotes | 5-HT6 receptor antagonist | ChemicalEntity | |
| T11 | 395-408 | ChemicalEntity | denotes | d-amphetamine | http://purl.obolibrary.org/obo/CHEBI_4469 | |
| T9 | 379-389 | ChemicalEntity | denotes | olanzapine | http://purl.obolibrary.org/obo/CHEBI_7735|D000077152 | |
| T7 | 365-374 | ChemicalEntity | denotes | clozapine | http://purl.obolibrary.org/obo/CHEBI_3766|D003024 | |
| T4 | 255-264 | ChemicalEntity | denotes | serotonin | http://purl.obolibrary.org/obo/CHEBI_28790|http://purl.obolibrary.org/obo/CHEBI_350546|D012701 | |
| T2 | 45-60 | ChemicalEntity | denotes | methamphetamine | http://purl.obolibrary.org/obo/CHEBI_6809|D008694 | |
| T1 | 0-9 | ChemicalEntity | denotes | Serotonin | http://purl.obolibrary.org/obo/CHEBI_28790 | |
| T10 | 1866-1870 | GeneOrGeneProduct | denotes | HTR6 | ||
| T14043 | 1798-1802 | GeneOrGeneProduct | denotes | HTR6 | ||
| T8 | 1652-1656 | GeneOrGeneProduct | denotes | wise | ||
| T24278 | 1543-1547 | GeneOrGeneProduct | denotes | wise | ||
| T6 | 1061-1065 | GeneOrGeneProduct | denotes | HTR6 | ||
| T5 | 1049-1054 | GeneOrGeneProduct | denotes | 5-HT6 | ||
| T79537 | 801-806 | GeneOrGeneProduct | denotes | 5-HT6 | ||
| T3 | 612-617 | GeneOrGeneProduct | denotes | 5-HT6 | ||
| T21282 | 480-485 | GeneOrGeneProduct | denotes | 5-HT6 | ||
| T82416 | 268-273 | GeneOrGeneProduct | denotes | 5-HT6 | ||
| T80913 | 1937-1946 | DiseaseOrPhenotypicFeature | denotes | psychosis | D011618 | |
| T79280 | 1820-1829 | DiseaseOrPhenotypicFeature | denotes | psychosis | D011618 | |
| T63507 | 1501-1510 | DiseaseOrPhenotypicFeature | denotes | psychosis | D011618 | |
| T64301 | 1274-1283 | DiseaseOrPhenotypicFeature | denotes | psychosis | D011618 | |
| T52210 | 1085-1094 | DiseaseOrPhenotypicFeature | denotes | psychosis | D011618 | |
| T23603 | 972-985 | DiseaseOrPhenotypicFeature | denotes | schizophrenia | D012559 | |
| T53747 | 924-933 | DiseaseOrPhenotypicFeature | denotes | psychosis | D011618 | |
| T58004 | 856-875 | DiseaseOrPhenotypicFeature | denotes | psychotic disorders | D011618 | |
| T49414 | 741-754 | DiseaseOrPhenotypicFeature | denotes | schizophrenia | D012559 | |
| T91803 | 417-430 | DiseaseOrPhenotypicFeature | denotes | hyperactivity | DISEASE | |
| T91903 | 236-249 | DiseaseOrPhenotypicFeature | denotes | schizophrenia | D012559 | |
| T97403 | 208-227 | DiseaseOrPhenotypicFeature | denotes | psychotic disorders | D011618 | |
| T83850 | 69-78 | DiseaseOrPhenotypicFeature | denotes | psychosis | D011618 | |
| T37616 | 1830-1838 | OrganismTaxon | denotes | patients | ||
| T12478 | 1511-1519 | OrganismTaxon | denotes | patients | ||
| T95619 | 1439-1447 | OrganismTaxon | denotes | patients | ||
| T78983 | 1284-1292 | OrganismTaxon | denotes | patients | ||
| T98834 | 663-667 | OrganismTaxon | denotes | rats | ||
| T37875 | 434-438 | OrganismTaxon | denotes | rats | ||
| T85724 | 1784-1793 | SequenceVariant | denotes | rs4912138 | ||
| T18283 | 1770-1779 | SequenceVariant | denotes | rs1805054 | ||
| T40889 | 1759-1768 | SequenceVariant | denotes | rs6693503 | ||
| T51212 | 1729-1738 | SequenceVariant | denotes | rs1805054 | ||
| T20212 | 1715-1724 | SequenceVariant | denotes | rs6693503 | ||
| T41685 | 1458-1467 | SequenceVariant | denotes | rs6693503 | ||
| T91080 | 1176-1185 | SequenceVariant | denotes | rs9659997 | ||
| T99960 | 1162-1171 | SequenceVariant | denotes | rs3790757 | ||
| T69827 | 1151-1160 | SequenceVariant | denotes | rs4912138 | ||
| T21856 | 1140-1149 | SequenceVariant | denotes | rs1805054 | ||
| T79203 | 1129-1138 | SequenceVariant | denotes | rs6693503 |
DisGeNET
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T0 | 1866-1870 | gene:3362 | denotes | HTR6 |
| T1 | 1929-1946 | disease:C0036939 | denotes | induced psychosis |
| R1 | T0 | T1 | associated_with | HTR6,induced psychosis |
PubmedHPO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 236-249 | HP_0100753 | denotes | schizophrenia |
| T2 | 417-430 | HP_0000752 | denotes | hyperactivity |
| T3 | 741-754 | HP_0100753 | denotes | schizophrenia |
| T4 | 924-933 | HP_0000709 | denotes | psychosis |
| T5 | 958-966 | HP_0011999 | denotes | paranoid |
| T6 | 972-985 | HP_0100753 | denotes | schizophrenia |
| T7 | 1085-1094 | HP_0000709 | denotes | psychosis |
Allie
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| SS1_20705401_6_0 | 893-908 | expanded | denotes | methamphetamine |
| SS2_20705401_6_0 | 910-914 | abbr | denotes | METH |
| AE1_20705401_6_0 | SS1_20705401_6_0 | SS2_20705401_6_0 | abbreviatedTo | methamphetamine,METH |
DisGeNET5_variant_disease
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 20705401-11#149#158#geners4912138 | 1784-1793 | geners4912138 | denotes | rs4912138 |
| 20705401-11#177#194#diseaseC0036939 | 1812-1829 | diseaseC0036939 | denotes | induced psychosis |
| 20705401-9#0#9#geners6693503 | 1458-1467 | geners6693503 | denotes | rs6693503 |
| 20705401-9#35#52#diseaseC0036939 | 1493-1510 | diseaseC0036939 | denotes | induced psychosis |
| 149#158#geners4912138177#194#diseaseC0036939 | 20705401-11#149#158#geners4912138 | 20705401-11#177#194#diseaseC0036939 | associated_with | rs4912138,induced psychosis |
| 0#9#geners669350335#52#diseaseC0036939 | 20705401-9#0#9#geners6693503 | 20705401-9#35#52#diseaseC0036939 | associated_with | rs6693503,induced psychosis |
DisGeNET5_gene_disease
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 20705401-12#0#4#gene3362 | 1866-1870 | gene3362 | denotes | HTR6 |
| 20705401-12#63#80#diseaseC0036939 | 1929-1946 | diseaseC0036939 | denotes | induced psychosis |
| 20705401-2#17#22#gene3362 | 268-273 | gene3362 | denotes | 5-HT6 |
| 20705401-2#229#234#gene3362 | 480-485 | gene3362 | denotes | 5-HT6 |
| 20705401-2#166#179#diseaseC0424295 | 417-430 | diseaseC0424295 | denotes | hyperactivity |
| 20705401-4#132#137#gene3362 | 801-806 | gene3362 | denotes | 5-HT6 |
| 20705401-4#187#206#diseaseC0033975 | 856-875 | diseaseC0033975 | denotes | psychotic disorders |
| 0#4#gene336263#80#diseaseC0036939 | 20705401-12#0#4#gene3362 | 20705401-12#63#80#diseaseC0036939 | associated_with | HTR6,induced psychosis |
| 17#22#gene3362166#179#diseaseC0424295 | 20705401-2#17#22#gene3362 | 20705401-2#166#179#diseaseC0424295 | associated_with | 5-HT6,hyperactivity |
| 229#234#gene3362166#179#diseaseC0424295 | 20705401-2#229#234#gene3362 | 20705401-2#166#179#diseaseC0424295 | associated_with | 5-HT6,hyperactivity |
| 132#137#gene3362187#206#diseaseC0033975 | 20705401-4#132#137#gene3362 | 20705401-4#187#206#diseaseC0033975 | associated_with | 5-HT6,psychotic disorders |