PubMed:20651814
Annnotations
LitCoin-entities-OrganismTaxon-PD
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 964-969 | OrganismTaxon | denotes | codon | NCBItxid:79338 |
LitCoin-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-116 | Sentence | denotes | Lack of association between ADRA2B-4825 gene insertion/deletion polymorphism and migraine in Chinese Han population. |
| T2 | 117-127 | Sentence | denotes | OBJECTIVE: |
| T3 | 128-343 | Sentence | denotes | The present study aimed to estimate the association between susceptibility to migraine and the 12-nucleotide insertion/deletion (indel) polymorphism in promoter region of alpha(2B)-adrenergic receptor gene (ADRA2B). |
| T4 | 344-352 | Sentence | denotes | METHODS: |
| T5 | 353-466 | Sentence | denotes | A case-control study was carried out in Chinese Han population, including 368 cases of migraine and 517 controls. |
| T6 | 467-589 | Sentence | denotes | Genomic DNA was extracted from blood samples, and DNA fragments containing the site of polymorphism were amplified by PCR. |
| T7 | 590-707 | Sentence | denotes | Data were adjusted for sex, age, migraine history and family history, and analyzed using a logistic regression model. |
| T8 | 708-716 | Sentence | denotes | RESULTS: |
| T9 | 717-826 | Sentence | denotes | There was no association between indel polymorphism and migraine, at either the allele or the genotype level. |
| T10 | 827-838 | Sentence | denotes | CONCLUSION: |
| T11 | 839-1046 | Sentence | denotes | These findings do not support a functional significance of ADRA2B indel polymorphism at position -4825 relative to the start codon in the far upstream region of the promoter in the present migraine subjects. |
LitCoin-entities
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| 7727 | 28-34 | GeneOrGeneProduct | denotes | ADRA2B | NCBIGene:151 |
| 7728 | 34-63 | SequenceVariant | denotes | -4825 gene insertion/deletion | c|INDEL|-4825|| |
| 7729 | 81-89 | DiseaseOrPhenotypicFeature | denotes | migraine | MESH:D008881 |
| 7730 | 206-214 | DiseaseOrPhenotypicFeature | denotes | migraine | MESH:D008881 |
| 7731 | 223-263 | SequenceVariant | denotes | 12-nucleotide insertion/deletion (indel) | c|INDEL||12 |
| 7732 | 299-328 | GeneOrGeneProduct | denotes | alpha(2B)-adrenergic receptor | NCBIGene:151 |
| 7733 | 335-341 | GeneOrGeneProduct | denotes | ADRA2B | NCBIGene:151 |
| 7734 | 440-448 | DiseaseOrPhenotypicFeature | denotes | migraine | MESH:D008881 |
| 7735 | 623-631 | DiseaseOrPhenotypicFeature | denotes | migraine | MESH:D008881 |
| 7736 | 773-781 | DiseaseOrPhenotypicFeature | denotes | migraine | MESH:D008881 |
| 7737 | 898-904 | GeneOrGeneProduct | denotes | ADRA2B | NCBIGene:151 |
| 7738 | 905-941 | SequenceVariant | denotes | indel polymorphism at position -4825 | c|INDEL|-4825|| |
| 7739 | 1028-1036 | DiseaseOrPhenotypicFeature | denotes | migraine | MESH:D008881 |
LitCoin-GeneOrGeneProduct-v0
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-4 | GeneOrGeneProduct | denotes | Lack |
| T2 | 28-34 | GeneOrGeneProduct | denotes | ADRA2B |
| T3 | 81-89 | GeneOrGeneProduct | denotes | migraine |
| T4 | 206-214 | GeneOrGeneProduct | denotes | migraine |
| T5 | 299-304 | GeneOrGeneProduct | denotes | alpha |
| T6 | 309-328 | GeneOrGeneProduct | denotes | adrenergic receptor |
| T7 | 335-341 | GeneOrGeneProduct | denotes | ADRA2B |
| T8 | 344-351 | GeneOrGeneProduct | denotes | METHODS |
| T9 | 355-359 | GeneOrGeneProduct | denotes | case |
| T10 | 386-389 | GeneOrGeneProduct | denotes | out |
| T11 | 431-436 | GeneOrGeneProduct | denotes | cases |
| T12 | 440-448 | GeneOrGeneProduct | denotes | migraine |
| T13 | 623-631 | GeneOrGeneProduct | denotes | migraine |
| T14 | 773-781 | GeneOrGeneProduct | denotes | migraine |
| T15 | 845-853 | GeneOrGeneProduct | denotes | findings |
| T16 | 898-904 | GeneOrGeneProduct | denotes | ADRA2B |
| T17 | 958-963 | GeneOrGeneProduct | denotes | start |
| T18 | 1028-1036 | GeneOrGeneProduct | denotes | migraine |
LitCoin-GeneOrGeneProduct-v2
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-4 | GeneOrGeneProduct | denotes | Lack |
| T2 | 28-34 | GeneOrGeneProduct | denotes | ADRA2B |
| T3 | 81-89 | GeneOrGeneProduct | denotes | migraine |
| T4 | 206-214 | GeneOrGeneProduct | denotes | migraine |
| T5 | 299-304 | GeneOrGeneProduct | denotes | alpha |
| T6 | 309-328 | GeneOrGeneProduct | denotes | adrenergic receptor |
| T7 | 335-341 | GeneOrGeneProduct | denotes | ADRA2B |
| T8 | 440-448 | GeneOrGeneProduct | denotes | migraine |
| T9 | 623-631 | GeneOrGeneProduct | denotes | migraine |
| T10 | 773-781 | GeneOrGeneProduct | denotes | migraine |
| T11 | 898-904 | GeneOrGeneProduct | denotes | ADRA2B |
| T12 | 958-963 | GeneOrGeneProduct | denotes | start |
| T13 | 1028-1036 | GeneOrGeneProduct | denotes | migraine |
LitCoin-Disease-MeSH
| Id | Subject | Object | Predicate | Lexical cue | originalLabel |
|---|---|---|---|---|---|
| T1 | 81-89 | DiseaseOrPhenotypicFeature | denotes | migraine | D008881 |
| T2 | 206-214 | DiseaseOrPhenotypicFeature | denotes | migraine | D008881 |
| T3 | 440-448 | DiseaseOrPhenotypicFeature | denotes | migraine | D008881 |
| T4 | 623-631 | DiseaseOrPhenotypicFeature | denotes | migraine | D008881 |
| T5 | 773-781 | DiseaseOrPhenotypicFeature | denotes | migraine | D008881 |
| T6 | 1028-1036 | DiseaseOrPhenotypicFeature | denotes | migraine | D008881 |
LitCoin-GeneOrGeneProduct-v3
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 28-34 | GeneOrGeneProduct | denotes | ADRA2B |
| T2 | 309-328 | GeneOrGeneProduct | denotes | adrenergic receptor |
| T3 | 335-341 | GeneOrGeneProduct | denotes | ADRA2B |
| T4 | 898-904 | GeneOrGeneProduct | denotes | ADRA2B |
LitCoin_Mondo_095
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 81-89 | DiseaseOrPhenotypicFeature | denotes | migraine | 0005277 |
| T2 | 206-214 | DiseaseOrPhenotypicFeature | denotes | migraine | 0005277 |
| T3 | 440-448 | DiseaseOrPhenotypicFeature | denotes | migraine | 0005277 |
| T4 | 623-631 | DiseaseOrPhenotypicFeature | denotes | migraine | 0005277 |
| T5 | 773-781 | DiseaseOrPhenotypicFeature | denotes | migraine | 0005277 |
| T6 | 1028-1036 | DiseaseOrPhenotypicFeature | denotes | migraine | 0005277 |
LitCoin-MeSH-Disease-2
| Id | Subject | Object | Predicate | Lexical cue | ID: |
|---|---|---|---|---|---|
| T1 | 81-89 | DiseaseOrPhenotypicFeature | denotes | migraine | D008881 |
| T2 | 206-214 | DiseaseOrPhenotypicFeature | denotes | migraine | D008881 |
| T3 | 440-448 | DiseaseOrPhenotypicFeature | denotes | migraine | D008881 |
| T4 | 623-631 | DiseaseOrPhenotypicFeature | denotes | migraine | D008881 |
| T5 | 773-781 | DiseaseOrPhenotypicFeature | denotes | migraine | D008881 |
| T6 | 1028-1036 | DiseaseOrPhenotypicFeature | denotes | migraine | D008881 |
LitCoin-MONDO_bioort2019
| Id | Subject | Object | Predicate | Lexical cue | #label |
|---|---|---|---|---|---|
| T1 | 81-89 | DiseaseOrPhenotypicFeature | denotes | migraine | D008881 |
| T2 | 206-214 | DiseaseOrPhenotypicFeature | denotes | migraine | D008881 |
| T3 | 440-448 | DiseaseOrPhenotypicFeature | denotes | migraine | D008881 |
| T4 | 623-631 | DiseaseOrPhenotypicFeature | denotes | migraine | D008881 |
| T5 | 773-781 | DiseaseOrPhenotypicFeature | denotes | migraine | D008881 |
| T6 | 1028-1036 | DiseaseOrPhenotypicFeature | denotes | migraine | D008881 |
LitCoin-training-merged
| Id | Subject | Object | Predicate | Lexical cue | #label |
|---|---|---|---|---|---|
| T4 | 898-904 | GeneOrGeneProduct | denotes | ADRA2B | |
| T3 | 335-341 | GeneOrGeneProduct | denotes | ADRA2B | |
| T2 | 309-328 | GeneOrGeneProduct | denotes | adrenergic receptor | |
| T1 | 28-34 | GeneOrGeneProduct | denotes | ADRA2B | |
| T6 | 1028-1036 | DiseaseOrPhenotypicFeature | denotes | migraine | D008881 |
| T5 | 773-781 | DiseaseOrPhenotypicFeature | denotes | migraine | D008881 |
| T33969 | 623-631 | DiseaseOrPhenotypicFeature | denotes | migraine | D008881 |
| T24033 | 440-448 | DiseaseOrPhenotypicFeature | denotes | migraine | D008881 |
| T97800 | 206-214 | DiseaseOrPhenotypicFeature | denotes | migraine | D008881 |
| T41738 | 81-89 | DiseaseOrPhenotypicFeature | denotes | migraine | D008881 |
DisGeNET
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T0 | 28-34 | gene:151 | denotes | ADRA2B |
| T1 | 81-89 | disease:C0149931 | denotes | migraine |
| T2 | 335-341 | gene:151 | denotes | ADRA2B |
| T3 | 206-214 | disease:C0149931 | denotes | migraine |
| T4 | 299-328 | gene:151 | denotes | alpha(2B)-adrenergic receptor |
| T5 | 206-214 | disease:C0149931 | denotes | migraine |
| T6 | 898-904 | gene:151 | denotes | ADRA2B |
| T7 | 1028-1036 | disease:C0149931 | denotes | migraine |
| R1 | T0 | T1 | associated_with | ADRA2B,migraine |
| R2 | T2 | T3 | associated_with | ADRA2B,migraine |
| R3 | T4 | T5 | associated_with | alpha(2B)-adrenergic receptor,migraine |
| R4 | T6 | T7 | associated_with | ADRA2B,migraine |
Allie
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| SS1_20651814_2_0 | 299-333 | expanded | denotes | alpha(2B)-adrenergic receptor gene |
| SS2_20651814_2_0 | 335-341 | abbr | denotes | ADRA2B |
| AE1_20651814_2_0 | SS1_20651814_2_0 | SS2_20651814_2_0 | abbreviatedTo | alpha(2B)-adrenergic receptor gene,ADRA2B |
PubmedHPO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 206-214 | HP_0002076 | denotes | migraine |