> top > docs > PubMed:20534142 > annotations

PubMed:20534142 JSONTXT

Annnotations TAB JSON ListView MergeView

PubTator4TogoVar

Id Subject Object Predicate Lexical cue proteinmutation
20534142_0 2014-2019 ProteinMutation denotes , inf rs6232

LitCoin-entities

Id Subject Object Predicate Lexical cue db_id
7472 15-22 DiseaseOrPhenotypicFeature denotes obesity MESH:D009765
7473 36-41 GeneOrGeneProduct denotes PCSK1 NCBIGene:5122
7474 47-54 GeneOrGeneProduct denotes insulin NCBIGene:3630
7475 71-81 ChemicalEntity denotes proinsulin MESH:D011384
7476 106-129 GeneOrGeneProduct denotes Prohormone convertase 1 NCBIGene:5122
7477 192-197 GeneOrGeneProduct denotes PCSK1 NCBIGene:5122
7478 237-244 DiseaseOrPhenotypicFeature denotes obesity MESH:D009765
7479 249-277 DiseaseOrPhenotypicFeature denotes abnormal glucose homeostasis MESH:D044882
7480 292-302 ChemicalEntity denotes proinsulin MESH:D011384
7481 383-389 SequenceVariant denotes rs6232 DBSNP:rs6232
7482 394-400 SequenceVariant denotes rs6235 DBSNP:rs6235
7483 422-429 DiseaseOrPhenotypicFeature denotes obesity MESH:D009765
7484 494-512 DiseaseOrPhenotypicFeature denotes insulin resistance MESH:D007333
7485 514-535 DiseaseOrPhenotypicFeature denotes beta-cell dysfunction
7486 540-559 DiseaseOrPhenotypicFeature denotes glucose intolerance MESH:D018149
7487 613-619 SequenceVariant denotes rs6232 DBSNP:rs6232
7488 624-630 SequenceVariant denotes rs6235 DBSNP:rs6235
7489 638-643 GeneOrGeneProduct denotes PCSK1 NCBIGene:5122
7490 699-706 ChemicalEntity denotes glucose MESH:D005947
7491 727-734 ChemicalEntity denotes glucose MESH:D005947
7492 736-743 GeneOrGeneProduct denotes insulin NCBIGene:3630
7493 745-755 ChemicalEntity denotes proinsulin MESH:D011384
7494 761-770 ChemicalEntity denotes C-peptide MESH:D002096
7495 824-851 DiseaseOrPhenotypicFeature denotes hyperinsulinemic-euglycemic MESH:D044903
7496 916-922 SequenceVariant denotes rs6235 DBSNP:rs6235
7497 936-942 SequenceVariant denotes rs6232 DBSNP:rs6232
7498 1010-1016 SequenceVariant denotes rs6235 DBSNP:rs6235
7499 1021-1027 SequenceVariant denotes rs6232 DBSNP:rs6232
7500 1138-1145 GeneOrGeneProduct denotes insulin NCBIGene:3630
7501 1191-1201 ChemicalEntity denotes proinsulin MESH:D011384
7502 1209-1219 ChemicalEntity denotes proinsulin MESH:D011384
7503 1223-1230 GeneOrGeneProduct denotes insulin NCBIGene:3630
7504 1232-1238 SequenceVariant denotes rs6235 DBSNP:rs6235
7505 1289-1295 SequenceVariant denotes rs6232 DBSNP:rs6232
7506 1346-1353 GeneOrGeneProduct denotes Insulin NCBIGene:3630
7507 1472-1478 SequenceVariant denotes rs6232 DBSNP:rs6232
7508 1565-1572 GeneOrGeneProduct denotes insulin NCBIGene:3630
7509 1660-1667 ChemicalEntity denotes glucose MESH:D005947
7510 1709-1719 ChemicalEntity denotes proinsulin MESH:D011384
7511 1736-1742 SequenceVariant denotes rs6235 DBSNP:rs6235
7512 1837-1842 GeneOrGeneProduct denotes PCSK1 NCBIGene:5122
7513 1886-1893 ChemicalEntity denotes glucose MESH:D005947
7514 1905-1915 ChemicalEntity denotes proinsulin MESH:D011384
7515 1936-1943 GeneOrGeneProduct denotes insulin NCBIGene:3630
7516 1968-1974 SequenceVariant denotes rs6232 DBSNP:rs6232
7517 2009-2014 SequenceVariant denotes N221D DBSNP:rs6232
7518 2027-2034 GeneOrGeneProduct denotes insulin NCBIGene:3630
7519 2051-2058 ChemicalEntity denotes glucose MESH:D005947

LitCoin-sentences

Id Subject Object Predicate Lexical cue
T1 0-93 Sentence denotes Association of obesity risk SNPs in PCSK1 with insulin sensitivity and proinsulin conversion.
T2 94-105 Sentence denotes BACKGROUND:
T3 106-168 Sentence denotes Prohormone convertase 1 is involved in maturation of peptides.
T4 169-318 Sentence denotes Rare mutations in gene PCSK1, encoding this enzyme, cause childhood obesity and abnormal glucose homeostasis with elevated proinsulin concentrations.
T5 319-430 Sentence denotes Common single nucleotide polymorphisms (SNPs) within this gene, rs6232 and rs6235, are associated with obesity.
T6 431-560 Sentence denotes We studied whether these SNPs influence the prediabetic traits insulin resistance, beta-cell dysfunction, or glucose intolerance.
T7 561-569 Sentence denotes METHODS:
T8 570-644 Sentence denotes We genotyped 1498 German subjects for SNPs rs6232 and rs6235 within PCSK1.
T9 645-784 Sentence denotes The subjects were metabolically characterized by oral glucose tolerance test with glucose, insulin, proinsulin, and C-peptide measurements.
T10 785-858 Sentence denotes A subgroup of 512 subjects underwent a hyperinsulinemic-euglycemic clamp.
T11 859-867 Sentence denotes RESULTS:
T12 868-943 Sentence denotes The minor allele frequencies were 25.8% for SNP rs6235 and 6.0% for rs6232.
T13 944-1086 Sentence denotes After adjustment for sex and age, we found no association of SNPs rs6235 and rs6232 with BMI or other weight-related traits (all p >or= 0.07).
T14 1087-1345 Sentence denotes Both minor alleles, adjusted for sex, age, BMI and insulin sensitivity were associated with elevated AUCproinsulin and AUCproinsulin/AUCinsulin (rs6235: p(additive) model <or= 0.009, effect sizes 8/8%, rs6232: pdominant model <or= 0.01, effect sizes 10/21%).
T15 1346-1447 Sentence denotes Insulin secretion was not affected by the variants (different secretion parameters, all p >or= 0.08).
T16 1448-1731 Sentence denotes The minor allele of SNP rs6232 was additionally associated with 15% higher OGTT-derived and 19% higher clamp-derived insulin sensitivity (pdom <or= 0.0047), 4.5% lower HOMAIR (pdom = 0.02) and 3.5% lower 120-min glucose (pdom = 0.0003) independently of BMI and proinsulin conversion.
T17 1732-1800 Sentence denotes SNP rs6235 was not associated with parameters of glucose metabolism.
T18 1801-1813 Sentence denotes CONCLUSIONS:
T19 1814-1954 Sentence denotes Like rare mutations in PCSK1, the more common variants tested determine glucose-stimulated proinsulin conversion, but not insulin secretion.
T20 1955-2071 Sentence denotes In addition, rs6232, encoding the amino acid exchange N221D, influences insulin sensitivity and glucose homeostasis.

LitCoin_Mondo

Id Subject Object Predicate Lexical cue mondo_id
T1 169-173 DiseaseOrPhenotypicFeature denotes Rare 0021136
T2 540-559 DiseaseOrPhenotypicFeature denotes glucose intolerance 0001076
T3 1819-1823 DiseaseOrPhenotypicFeature denotes rare 0021136

LitCoin-SeqVar

Id Subject Object Predicate Lexical cue
T1 383-389 SequenceVariant denotes rs6232
T2 394-400 SequenceVariant denotes rs6235
T3 613-619 SequenceVariant denotes rs6232
T4 624-630 SequenceVariant denotes rs6235
T5 916-922 SequenceVariant denotes rs6235
T6 936-942 SequenceVariant denotes rs6232
T7 1010-1016 SequenceVariant denotes rs6235
T8 1021-1027 SequenceVariant denotes rs6232
T9 1232-1238 SequenceVariant denotes rs6235
T10 1289-1295 SequenceVariant denotes rs6232
T11 1472-1478 SequenceVariant denotes rs6232
T12 1736-1742 SequenceVariant denotes rs6235
T13 1968-1974 SequenceVariant denotes rs6232
T14 2009-2014 SequenceVariant denotes N221D

LitCoin-GeneOrGeneProduct-v0

Id Subject Object Predicate Lexical cue
T1 15-22 GeneOrGeneProduct denotes obesity
T2 36-41 GeneOrGeneProduct denotes PCSK1
T3 47-54 GeneOrGeneProduct denotes insulin
T4 71-81 GeneOrGeneProduct denotes proinsulin
T5 106-129 GeneOrGeneProduct denotes Prohormone convertase 1
T6 145-155 GeneOrGeneProduct denotes maturation
T7 169-173 GeneOrGeneProduct denotes Rare
T8 174-183 GeneOrGeneProduct denotes mutations
T9 192-197 GeneOrGeneProduct denotes PCSK1
T10 213-219 GeneOrGeneProduct denotes enzyme
T11 237-244 GeneOrGeneProduct denotes obesity
T12 292-302 GeneOrGeneProduct denotes proinsulin
T13 422-429 GeneOrGeneProduct denotes obesity
T14 487-493 GeneOrGeneProduct denotes traits
T15 494-501 GeneOrGeneProduct denotes insulin
T16 514-518 GeneOrGeneProduct denotes beta
T17 519-523 GeneOrGeneProduct denotes cell
T18 561-568 GeneOrGeneProduct denotes METHODS
T19 638-643 GeneOrGeneProduct denotes PCSK1
T20 707-716 GeneOrGeneProduct denotes tolerance
T21 717-721 GeneOrGeneProduct denotes test
T22 736-743 GeneOrGeneProduct denotes insulin
T23 745-755 GeneOrGeneProduct denotes proinsulin
T24 761-770 GeneOrGeneProduct denotes C-peptide
T25 852-857 GeneOrGeneProduct denotes clamp
T26 872-877 GeneOrGeneProduct denotes minor
T27 885-896 GeneOrGeneProduct denotes frequencies
T28 1040-1045 GeneOrGeneProduct denotes other
T29 1061-1067 GeneOrGeneProduct denotes traits
T30 1069-1074 GeneOrGeneProduct denotes all p
T31 1092-1097 GeneOrGeneProduct denotes minor
T32 1138-1145 GeneOrGeneProduct denotes insulin
T33 1277-1282 GeneOrGeneProduct denotes sizes
T34 1331-1336 GeneOrGeneProduct denotes sizes
T35 1346-1353 GeneOrGeneProduct denotes Insulin
T36 1354-1363 GeneOrGeneProduct denotes secretion
T37 1408-1417 GeneOrGeneProduct denotes secretion
T38 1430-1435 GeneOrGeneProduct denotes all p
T39 1452-1457 GeneOrGeneProduct denotes minor
T40 1551-1556 GeneOrGeneProduct denotes clamp
T41 1565-1572 GeneOrGeneProduct denotes insulin
T42 1709-1719 GeneOrGeneProduct denotes proinsulin
T43 1814-1818 GeneOrGeneProduct denotes Like
T44 1819-1823 GeneOrGeneProduct denotes rare
T45 1824-1833 GeneOrGeneProduct denotes mutations
T46 1837-1842 GeneOrGeneProduct denotes PCSK1
T47 1869-1875 GeneOrGeneProduct denotes tested
T48 1876-1885 GeneOrGeneProduct denotes determine
T49 1905-1915 GeneOrGeneProduct denotes proinsulin
T50 1936-1943 GeneOrGeneProduct denotes insulin
T51 1944-1953 GeneOrGeneProduct denotes secretion
T52 1989-1999 GeneOrGeneProduct denotes amino acid
T53 2027-2034 GeneOrGeneProduct denotes insulin

LitCoin-GeneOrGeneProduct-v2

Id Subject Object Predicate Lexical cue
T1 36-41 GeneOrGeneProduct denotes PCSK1
T2 47-54 GeneOrGeneProduct denotes insulin
T3 71-81 GeneOrGeneProduct denotes proinsulin
T4 106-129 GeneOrGeneProduct denotes Prohormone convertase 1
T5 145-155 GeneOrGeneProduct denotes maturation
T6 192-197 GeneOrGeneProduct denotes PCSK1
T7 213-219 GeneOrGeneProduct denotes enzyme
T8 292-302 GeneOrGeneProduct denotes proinsulin
T9 487-493 GeneOrGeneProduct denotes traits
T10 494-501 GeneOrGeneProduct denotes insulin
T11 514-518 GeneOrGeneProduct denotes beta
T12 519-523 GeneOrGeneProduct denotes cell
T13 638-643 GeneOrGeneProduct denotes PCSK1
T14 736-743 GeneOrGeneProduct denotes insulin
T15 745-755 GeneOrGeneProduct denotes proinsulin
T16 761-770 GeneOrGeneProduct denotes C-peptide
T17 852-857 GeneOrGeneProduct denotes clamp
T18 872-877 GeneOrGeneProduct denotes minor
T19 1040-1045 GeneOrGeneProduct denotes other
T20 1061-1067 GeneOrGeneProduct denotes traits
T21 1092-1097 GeneOrGeneProduct denotes minor
T22 1138-1145 GeneOrGeneProduct denotes insulin
T23 1346-1353 GeneOrGeneProduct denotes Insulin
T24 1452-1457 GeneOrGeneProduct denotes minor
T25 1551-1556 GeneOrGeneProduct denotes clamp
T26 1565-1572 GeneOrGeneProduct denotes insulin
T27 1709-1719 GeneOrGeneProduct denotes proinsulin
T28 1819-1823 GeneOrGeneProduct denotes rare
T29 1837-1842 GeneOrGeneProduct denotes PCSK1
T30 1905-1915 GeneOrGeneProduct denotes proinsulin
T31 1936-1943 GeneOrGeneProduct denotes insulin
T32 1989-1999 GeneOrGeneProduct denotes amino acid
T33 2027-2034 GeneOrGeneProduct denotes insulin

LitCoin-Disease-MeSH

Id Subject Object Predicate Lexical cue originalLabel
T1 15-22 DiseaseOrPhenotypicFeature denotes obesity D009765
T2 47-66 DiseaseOrPhenotypicFeature denotes insulin sensitivity D007333
T3 227-244 DiseaseOrPhenotypicFeature denotes childhood obesity D063766
T4 422-429 DiseaseOrPhenotypicFeature denotes obesity D009765
T5 475-486 DiseaseOrPhenotypicFeature denotes prediabetic D011236
T6 494-512 DiseaseOrPhenotypicFeature denotes insulin resistance D007333
T7 540-559 DiseaseOrPhenotypicFeature denotes glucose intolerance D018149
T8 1138-1157 DiseaseOrPhenotypicFeature denotes insulin sensitivity D007333
T9 1565-1584 DiseaseOrPhenotypicFeature denotes insulin sensitivity D007333
T10 2027-2046 DiseaseOrPhenotypicFeature denotes insulin sensitivity D007333

LitCoin-GeneOrGeneProduct-v3

Id Subject Object Predicate Lexical cue
T1 36-41 GeneOrGeneProduct denotes PCSK1
T2 106-129 GeneOrGeneProduct denotes Prohormone convertase 1
T3 192-197 GeneOrGeneProduct denotes PCSK1
T4 638-643 GeneOrGeneProduct denotes PCSK1
T5 1837-1842 GeneOrGeneProduct denotes PCSK1

LitCoin_Mondo_095

Id Subject Object Predicate Lexical cue mondo_id
T1 15-22 DiseaseOrPhenotypicFeature denotes obesity 0011122
T2 55-66 DiseaseOrPhenotypicFeature denotes sensitivity 0000605
T3 237-244 DiseaseOrPhenotypicFeature denotes obesity 0011122
T4 422-429 DiseaseOrPhenotypicFeature denotes obesity 0011122
T5 540-559 DiseaseOrPhenotypicFeature denotes glucose intolerance 0001076
T6 1146-1157 DiseaseOrPhenotypicFeature denotes sensitivity 0000605
T7 1573-1584 DiseaseOrPhenotypicFeature denotes sensitivity 0000605
T8 2035-2046 DiseaseOrPhenotypicFeature denotes sensitivity 0000605

LitCoin-MeSH-Disease-2

Id Subject Object Predicate Lexical cue ID:
T1 15-22 DiseaseOrPhenotypicFeature denotes obesity D009765
T2 47-66 DiseaseOrPhenotypicFeature denotes insulin sensitivity D007333
T3 227-244 DiseaseOrPhenotypicFeature denotes childhood obesity D063766
T4 249-277 DiseaseOrPhenotypicFeature denotes abnormal glucose homeostasis DISEASE
T5 422-429 DiseaseOrPhenotypicFeature denotes obesity D009765
T6 494-512 DiseaseOrPhenotypicFeature denotes insulin resistance D007333
T7 514-535 DiseaseOrPhenotypicFeature denotes beta-cell dysfunction DISEASE
T8 540-559 DiseaseOrPhenotypicFeature denotes glucose intolerance D018149
T9 824-851 DiseaseOrPhenotypicFeature denotes hyperinsulinemic-euglycemic DISEASE
T10 1138-1157 DiseaseOrPhenotypicFeature denotes insulin sensitivity D007333
T11 1565-1584 DiseaseOrPhenotypicFeature denotes insulin sensitivity D007333
T12 2027-2046 DiseaseOrPhenotypicFeature denotes insulin sensitivity D007333

LitCoin-MONDO_bioort2019

Id Subject Object Predicate Lexical cue #label
T1 15-22 DiseaseOrPhenotypicFeature denotes obesity D009765
T2 227-244 DiseaseOrPhenotypicFeature denotes childhood obesity D063766
T3 249-277 DiseaseOrPhenotypicFeature denotes abnormal glucose homeostasis DISEASE
T4 422-429 DiseaseOrPhenotypicFeature denotes obesity D009765
T5 494-512 DiseaseOrPhenotypicFeature denotes insulin resistance D007333
T6 514-535 DiseaseOrPhenotypicFeature denotes beta-cell dysfunction DISEASE
T7 540-559 DiseaseOrPhenotypicFeature denotes glucose intolerance D018149
T8 824-851 DiseaseOrPhenotypicFeature denotes hyperinsulinemic-euglycemic DISEASE

LitCoin-Chemical-MeSH-CHEBI

Id Subject Object Predicate Lexical cue ID:
T1 71-81 ChemicalEntity denotes proinsulin ChemicalEntity
T2 106-129 ChemicalEntity denotes Prohormone convertase 1 D045664
T3 258-265 ChemicalEntity denotes glucose D005947|http://purl.obolibrary.org/obo/CHEBI_4167|http://purl.obolibrary.org/obo/CHEBI_17234
T6 292-302 ChemicalEntity denotes proinsulin ChemicalEntity
T7 540-547 ChemicalEntity denotes glucose D005947|http://purl.obolibrary.org/obo/CHEBI_4167|http://purl.obolibrary.org/obo/CHEBI_17234
T10 699-706 ChemicalEntity denotes glucose D005947|http://purl.obolibrary.org/obo/CHEBI_4167|http://purl.obolibrary.org/obo/CHEBI_17234
T13 727-734 ChemicalEntity denotes glucose D005947|http://purl.obolibrary.org/obo/CHEBI_4167|http://purl.obolibrary.org/obo/CHEBI_17234
T16 745-755 ChemicalEntity denotes proinsulin ChemicalEntity
T17 761-770 ChemicalEntity denotes C-peptide http://purl.obolibrary.org/obo/CHEBI_80332
T18 1660-1667 ChemicalEntity denotes glucose D005947|http://purl.obolibrary.org/obo/CHEBI_4167|http://purl.obolibrary.org/obo/CHEBI_17234
T21 1709-1719 ChemicalEntity denotes proinsulin ChemicalEntity
T22 1781-1788 ChemicalEntity denotes glucose D005947|http://purl.obolibrary.org/obo/CHEBI_4167|http://purl.obolibrary.org/obo/CHEBI_17234
T25 1886-1893 ChemicalEntity denotes glucose D005947|http://purl.obolibrary.org/obo/CHEBI_4167|http://purl.obolibrary.org/obo/CHEBI_17234
T28 1905-1915 ChemicalEntity denotes proinsulin ChemicalEntity
T29 2051-2058 ChemicalEntity denotes glucose D005947|http://purl.obolibrary.org/obo/CHEBI_4167|http://purl.obolibrary.org/obo/CHEBI_17234

LitCoin-training-merged

Id Subject Object Predicate Lexical cue #label ID:
T29 2051-2058 ChemicalEntity denotes glucose http://purl.obolibrary.org/obo/CHEBI_17234|http://purl.obolibrary.org/obo/CHEBI_4167|D005947
T28 1905-1915 ChemicalEntity denotes proinsulin ChemicalEntity
T25 1886-1893 ChemicalEntity denotes glucose http://purl.obolibrary.org/obo/CHEBI_17234|http://purl.obolibrary.org/obo/CHEBI_4167|D005947
T22 1781-1788 ChemicalEntity denotes glucose http://purl.obolibrary.org/obo/CHEBI_17234|http://purl.obolibrary.org/obo/CHEBI_4167|D005947
T21 1709-1719 ChemicalEntity denotes proinsulin ChemicalEntity
T18 1660-1667 ChemicalEntity denotes glucose http://purl.obolibrary.org/obo/CHEBI_17234|http://purl.obolibrary.org/obo/CHEBI_4167|D005947
T17 761-770 ChemicalEntity denotes C-peptide http://purl.obolibrary.org/obo/CHEBI_80332
T16 745-755 ChemicalEntity denotes proinsulin ChemicalEntity
T13 727-734 ChemicalEntity denotes glucose http://purl.obolibrary.org/obo/CHEBI_17234|http://purl.obolibrary.org/obo/CHEBI_4167|D005947
T10 699-706 ChemicalEntity denotes glucose http://purl.obolibrary.org/obo/CHEBI_17234|http://purl.obolibrary.org/obo/CHEBI_4167|D005947
T7 540-547 ChemicalEntity denotes glucose http://purl.obolibrary.org/obo/CHEBI_17234|http://purl.obolibrary.org/obo/CHEBI_4167|D005947
T6 292-302 ChemicalEntity denotes proinsulin ChemicalEntity
T3 258-265 ChemicalEntity denotes glucose http://purl.obolibrary.org/obo/CHEBI_17234|http://purl.obolibrary.org/obo/CHEBI_4167|D005947
T2 106-129 ChemicalEntity denotes Prohormone convertase 1 D045664
T1 71-81 ChemicalEntity denotes proinsulin ChemicalEntity
T5 1837-1842 GeneOrGeneProduct denotes PCSK1
T4 638-643 GeneOrGeneProduct denotes PCSK1
T38704 192-197 GeneOrGeneProduct denotes PCSK1
T35555 106-129 GeneOrGeneProduct denotes Prohormone convertase 1
T37650 36-41 GeneOrGeneProduct denotes PCSK1
T8 824-851 DiseaseOrPhenotypicFeature denotes hyperinsulinemic-euglycemic DISEASE
T95521 540-559 DiseaseOrPhenotypicFeature denotes glucose intolerance D018149
T63991 514-535 DiseaseOrPhenotypicFeature denotes beta-cell dysfunction DISEASE
T33461 494-512 DiseaseOrPhenotypicFeature denotes insulin resistance D007333
T85779 422-429 DiseaseOrPhenotypicFeature denotes obesity D009765
T29348 249-277 DiseaseOrPhenotypicFeature denotes abnormal glucose homeostasis DISEASE
T78923 227-244 DiseaseOrPhenotypicFeature denotes childhood obesity D063766
T46141 15-22 DiseaseOrPhenotypicFeature denotes obesity D009765
T14 2009-2014 SequenceVariant denotes N221D
T4581 1968-1974 SequenceVariant denotes rs6232
T12 1736-1742 SequenceVariant denotes rs6235
T11 1472-1478 SequenceVariant denotes rs6232
T56073 1289-1295 SequenceVariant denotes rs6232
T9 1232-1238 SequenceVariant denotes rs6235
T68862 1021-1027 SequenceVariant denotes rs6232
T94266 1010-1016 SequenceVariant denotes rs6235
T90830 936-942 SequenceVariant denotes rs6232
T17106 916-922 SequenceVariant denotes rs6235
T83049 624-630 SequenceVariant denotes rs6235
T4152 613-619 SequenceVariant denotes rs6232
T8159 394-400 SequenceVariant denotes rs6235
T1717 383-389 SequenceVariant denotes rs6232

DisGeNET

Id Subject Object Predicate Lexical cue
T0 36-41 gene:5122 denotes PCSK1
T1 15-22 disease:C0028754 denotes obesity
T2 47-54 gene:723961 denotes insulin
T3 15-22 disease:C0028754 denotes obesity
T4 47-54 gene:3630 denotes insulin
T5 15-22 disease:C0028754 denotes obesity
T6 71-81 gene:3630 denotes proinsulin
T7 15-22 disease:C0028754 denotes obesity
T8 292-302 gene:3630 denotes proinsulin
T9 227-244 disease:C2362324 denotes childhood obesity
T10 292-302 gene:3630 denotes proinsulin
T11 227-244 disease:C3645710 denotes childhood obesity
R1 T0 T1 associated_with PCSK1,obesity
R2 T2 T3 associated_with insulin,obesity
R3 T4 T5 associated_with insulin,obesity
R4 T6 T7 associated_with proinsulin,obesity
R5 T8 T9 associated_with proinsulin,childhood obesity
R6 T10 T11 associated_with proinsulin,childhood obesity

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 237-244 HP_0001513 denotes obesity
T2 249-277 HP_0011014 denotes abnormal glucose homeostasis
T3 422-429 HP_0001513 denotes obesity
T4 494-512 HP_0000855 denotes insulin resistance
T5 514-535 HP_0006279 denotes beta-cell dysfunction
T6 540-559 HP_0000833 denotes glucose intolerance

Allie

Id Subject Object Predicate Lexical cue
SS1_20534142_4_0 326-357 expanded denotes single nucleotide polymorphisms
SS2_20534142_4_0 359-363 abbr denotes SNPs
AE1_20534142_4_0 SS1_20534142_4_0 SS2_20534142_4_0 abbreviatedTo single nucleotide polymorphisms,SNPs

DisGeNET5_gene_disease

Id Subject Object Predicate Lexical cue
20534142-0#36#41#gene5122 36-41 gene5122 denotes PCSK1
20534142-0#71#81#gene3630 71-81 gene3630 denotes proinsulin
20534142-0#15#22#diseaseC0028754 15-22 diseaseC0028754 denotes obesity
36#41#gene512215#22#diseaseC0028754 20534142-0#36#41#gene5122 20534142-0#15#22#diseaseC0028754 associated_with PCSK1,obesity
71#81#gene363015#22#diseaseC0028754 20534142-0#71#81#gene3630 20534142-0#15#22#diseaseC0028754 associated_with proinsulin,obesity

tmVarCorpus

Id Subject Object Predicate Lexical cue
T1 383-389 SNP:rs6232 denotes rs6232
T2 394-400 SNP:rs6235 denotes rs6235
T3 613-619 SNP:rs6232 denotes rs6232
T4 624-630 SNP:rs6235 denotes rs6235
T5 916-922 SNP:rs6235 denotes rs6235
T6 936-942 SNP:rs6232 denotes rs6232
T7 1010-1016 SNP:rs6235 denotes rs6235
T8 1021-1027 SNP:rs6232 denotes rs6232
T9 1232-1238 SNP:rs6235 denotes rs6235
T10 1289-1295 SNP:rs6232 denotes rs6232
T11 1472-1478 SNP:rs6232 denotes rs6232
T12 1736-1742 SNP:rs6235 denotes rs6235
T13 1968-1974 SNP:rs6232 denotes rs6232
T14 2009-2014 ProteinMutation:p|SUB|N|221|D denotes N221D