PubMed:20512609
Annnotations
GoldHamster
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 32-43 | D006965 | denotes | hyperplasia |
| T2 | 32-43 | D006965 | denotes | hyperplasia |
| T3 | 48-53 | UBERON:0001977 | denotes | serum |
| T4 | 157-165 | UBERON:0001637 | denotes | arteries |
| T5 | 275-278 | P08798 | denotes | PSV |
| T6 | 335-340 | UBERON:0001977 | denotes | serum |
| T7 | 470-481 | D006965 | denotes | hyperplasia |
| T8 | 470-481 | D006965 | denotes | hyperplasia |
| T9 | 507-520 | UBERON:2000098 | denotes | proliferation |
| T10 | 748-753 | UBERON:0001977 | denotes | serum |
| T11 | 799-804 | UBERON:0001977 | denotes | serum |
| T12 | 884-897 | UBERON:2000098 | denotes | proliferation |
| T13 | 1129-1142 | UBERON:2000098 | denotes | proliferation |
| T14 | 1147-1153 | UBERON:0000055 | denotes | vessel |
| T15 | 1322-1335 | UBERON:2000098 | denotes | proliferation |
PubMed_ArguminSci
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 138-249 | DRI_Background | denotes | Ex vivo culture of arteries and veins is an established tool for investigating mechanically induced remodeling. |
| T2 | 250-334 | DRI_Background | denotes | Porcine saphenous veins (PSV) cultured ex vivo with a venous mechanical environment, |
| T3 | 367-669 | DRI_Background | denotes | medium and standard cell-culture conditions (5% CO₂ and 95% balance air ~140 mmHg pO₂) develop intimal hyperplasia (IH), increased cellular proliferation, decreased compliance and exhibit inward eutrophic remodeling thereby suggesting that nonmechanical factors stimulate some changes observed ex vivo. |
| T4 | 670-789 | DRI_Outcome | denotes | Herein we explore the contribution of exposure to greater than venous pO₂ and serum to these changes in cultured veins. |
| T5 | 790-930 | DRI_Background | denotes | Removing serum from culture medium did not inhibit development of IH, but did reduce cellular proliferation and inward eutrophic remodeling. |
| T6 | 931-1005 | DRI_Background | denotes | In contrast, veins perfused using reduced pO₂ (75 mmHg) showed reduced IH. |
| T7 | 1006-1223 | DRI_Outcome | denotes | Among the statically cultured vessels, veins cultured at arterial pO₂ (95 mmHg) and above showed IH as well as increase in proliferation and vessel weight compared to fresh veins; veins cultured at venous pO₂ did not. |
| T8 | 1224-1472 | DRI_Approach | denotes | Taken together, these data suggest that exposure of SV to arterial pO₂ stimulates IH and cellular proliferation independent of changes in the mechanical environment, which might provide insight into the etiology of IH in SV used as arterial grafts. |
Goldhamster2_Cellosaurus
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 9-11 | CVCL_2676|Cancer_cell_line|Homo sapiens | denotes | pO |
| T2 | 9-11 | CVCL_N593|Spontaneously_immortalized_cell_line|Ovis aries | denotes | pO |
| T3 | 179-181 | CVCL_8754|Cancer_cell_line|Homo sapiens | denotes | an |
| T4 | 179-181 | CVCL_H241|Cancer_cell_line|Homo sapiens | denotes | an |
| T5 | 302-303 | CVCL_6479|Finite_cell_line|Mus musculus | denotes | a |
| T6 | 415-425 | CVCL_9T89|Cancer_cell_line|Homo sapiens | denotes | CO₂ and 95 |
| T7 | 415-417 | CVCL_J653|Cancer_cell_line|Homo sapiens | denotes | CO |
| T8 | 449-451 | CVCL_2676|Cancer_cell_line|Homo sapiens | denotes | pO |
| T9 | 449-451 | CVCL_N593|Spontaneously_immortalized_cell_line|Ovis aries | denotes | pO |
| T10 | 644-651 | CVCL_0238|Cancer_cell_line|Homo sapiens | denotes | changes |
| T11 | 677-679 | CVCL_5M23|Cancer_cell_line|Mesocricetus auratus | denotes | we |
| T12 | 740-742 | CVCL_2676|Cancer_cell_line|Homo sapiens | denotes | pO |
| T13 | 740-742 | CVCL_N593|Spontaneously_immortalized_cell_line|Ovis aries | denotes | pO |
| T14 | 763-770 | CVCL_0238|Cancer_cell_line|Homo sapiens | denotes | changes |
| T15 | 973-975 | CVCL_2676|Cancer_cell_line|Homo sapiens | denotes | pO |
| T16 | 973-975 | CVCL_N593|Spontaneously_immortalized_cell_line|Ovis aries | denotes | pO |
| T17 | 1072-1074 | CVCL_2676|Cancer_cell_line|Homo sapiens | denotes | pO |
| T18 | 1072-1074 | CVCL_N593|Spontaneously_immortalized_cell_line|Ovis aries | denotes | pO |
| T19 | 1211-1213 | CVCL_2676|Cancer_cell_line|Homo sapiens | denotes | pO |
| T20 | 1211-1213 | CVCL_N593|Spontaneously_immortalized_cell_line|Ovis aries | denotes | pO |
| T21 | 1276-1278 | CVCL_E938|Transformed_cell_line|Mus musculus | denotes | SV |
| T22 | 1291-1293 | CVCL_2676|Cancer_cell_line|Homo sapiens | denotes | pO |
| T23 | 1291-1293 | CVCL_N593|Spontaneously_immortalized_cell_line|Ovis aries | denotes | pO |
| T24 | 1351-1358 | CVCL_0238|Cancer_cell_line|Homo sapiens | denotes | changes |
| T25 | 1445-1447 | CVCL_E938|Transformed_cell_line|Mus musculus | denotes | SV |
Allie
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| SS1_20512609_2_0 | 250-273 | expanded | denotes | Porcine saphenous veins |
| SS2_20512609_2_0 | 275-278 | abbr | denotes | PSV |
| SS1_20512609_2_1 | 462-481 | expanded | denotes | intimal hyperplasia |
| SS2_20512609_2_1 | 483-485 | abbr | denotes | IH |
| AE1_20512609_2_0 | SS1_20512609_2_0 | SS2_20512609_2_0 | abbreviatedTo | Porcine saphenous veins,PSV |
| AE1_20512609_2_1 | SS1_20512609_2_1 | SS2_20512609_2_1 | abbreviatedTo | intimal hyperplasia,IH |