PubMed:2034676
Annnotations
DisGeNET
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T0 | 1456-1462 | gene:4005 | denotes | Rhom-2 |
| T1 | 1516-1531 | disease:C0023492 | denotes | T-cell leukemia |
| R1 | T0 | T1 | associated_with | Rhom-2,T-cell leukemia |
PubmedHPO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 193-201 | HP_0001909 | denotes | leukemia |
| T2 | 216-225 | HP_0009824 | denotes | short arm |
| T3 | 325-335 | HP_0009609 | denotes | duplicated |
| T4 | 635-643 | HP_0001909 | denotes | leukemia |
| T5 | 1203-1209 | HP_0002664 | denotes | tumors |
| T6 | 1523-1531 | HP_0001909 | denotes | leukemia |
| T7 | 1658-1668 | HP_0009609 | denotes | duplicated |
jnlpba-st-training
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 4-20 | DNA | denotes | rhombotin family |
| T2 | 24-58 | DNA | denotes | cysteine-rich LIM-domain oncogenes |
| T3 | 93-114 | DNA | denotes | T-cell translocations |
| T4 | 118-151 | DNA | denotes | human chromosomes 11p15 and 11p13 |
| T5 | 216-225 | DNA | denotes | short arm |
| T6 | 229-248 | DNA | denotes | human chromosome 11 |
| T7 | 252-262 | DNA | denotes | band 11p15 |
| T8 | 276-290 | DNA | denotes | rhombotin gene |
| T9 | 336-357 | protein | denotes | cysteine-rich regions |
| T10 | 365-376 | protein | denotes | LIM domains |
| T11 | 401-422 | protein | denotes | zinc-binding proteins |
| T12 | 430-449 | protein | denotes | iron-sulfur centers |
| T13 | 453-464 | protein | denotes | ferredoxins |
| T14 | 488-502 | DNA | denotes | rhombotin gene |
| T15 | 552-558 | DNA | denotes | Rhom-2 |
| T16 | 574-593 | DNA | denotes | human chromosome 11 |
| T17 | 597-607 | DNA | denotes | band 11p13 |
| T18 | 628-667 | DNA | denotes | T-cell leukemia-specific translocations |
| T19 | 708-713 | DNA | denotes | 11p13 |
| T20 | 734-745 | DNA | denotes | Rhom-2 gene |
| T21 | 747-769 | DNA | denotes | Human and mouse Rhom-2 |
| T22 | 801-810 | DNA | denotes | rhombotin |
| T23 | 823-855 | DNA | denotes | tandem cysteine-rich LIM domains |
| T24 | 857-868 | RNA | denotes | Rhom-2 mRNA |
| T25 | 1037-1043 | DNA | denotes | Rhom-3 |
| T26 | 1102-1112 | DNA | denotes | LIM domain |
| T27 | 1116-1125 | DNA | denotes | rhombotin |
| T28 | 1137-1148 | DNA | denotes | Rhom-2 gene |
| T29 | 1196-1209 | cell_type | denotes | T-cell tumors |
| T30 | 1254-1268 | DNA | denotes | rhombotin gene |
| T31 | 1326-1335 | DNA | denotes | rhombotin |
| T32 | 1410-1432 | DNA | denotes | chromosome bands 11p15 |
| T33 | 1434-1443 | DNA | denotes | rhombotin |
| T34 | 1449-1454 | DNA | denotes | 11p13 |
| T35 | 1456-1462 | DNA | denotes | Rhom-2 |
| T36 | 1542-1554 | DNA | denotes | 11p15 target |
| T37 | 1600-1609 | DNA | denotes | rhombotin |
| T38 | 1636-1652 | DNA | denotes | T-cell oncogenes |
| T39 | 1669-1694 | DNA | denotes | cysteine-rich LIM domains |
DisGeNET5_gene_disease
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 2034676-10#57#63#gene4005 | 1456-1462 | gene4005 | denotes | Rhom-2 |
| 2034676-10#117#132#diseaseC0023492 | 1516-1531 | diseaseC0023492 | denotes | T-cell leukemia |
| 57#63#gene4005117#132#diseaseC0023492 | 2034676-10#57#63#gene4005 | 2034676-10#117#132#diseaseC0023492 | associated_with | Rhom-2,T-cell leukemia |
pubmed-sentences-benchmark
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| S1 | 0-152 | Sentence | denotes | The rhombotin family of cysteine-rich LIM-domain oncogenes: distinct members are involved in T-cell translocations to human chromosomes 11p15 and 11p13. |
| S2 | 153-291 | Sentence | denotes | A chromosomal translocation in a T-cell leukemia involving the short arm of human chromosome 11 at band 11p15 disrupts the rhombotin gene. |
| S3 | 292-465 | Sentence | denotes | This gene encodes a protein with duplicated cysteine-rich regions called LIM domains, which show homology to zinc-binding proteins and to iron-sulfur centers of ferredoxins. |
| S4 | 466-526 | Sentence | denotes | Two homologues of the rhombotin gene have now been isolated. |
| S5 | 527-746 | Sentence | denotes | One of these, designated Rhom-2, is located on human chromosome 11 at band 11p13, where a cluster of T-cell leukemia-specific translocations occur; all translocation breakpoints at 11p13 are upstream of the Rhom-2 gene. |
| S6 | 747-856 | Sentence | denotes | Human and mouse Rhom-2 are highly conserved and, like rhombotin, encode two tandem cysteine-rich LIM domains. |
| S7 | 857-1009 | Sentence | denotes | Rhom-2 mRNA is expressed in early mouse development in central nervous system, lung, kidney, liver, and spleen but only very low levels occur in thymus. |
| S8 | 1010-1126 | Sentence | denotes | The other gene, designated Rhom-3, is not on chromosome 11 but also retains homology to the LIM domain of rhombotin. |
| S9 | 1127-1290 | Sentence | denotes | Since the Rhom-2 gene is such a common site of chromosomal damage in T-cell tumors, the consistency of translocations near the rhombotin gene was further examined. |
| S10 | 1291-1398 | Sentence | denotes | A second translocation adjacent to rhombotin was found and at the same position as in the previous example. |
| S11 | 1399-1576 | Sentence | denotes | Therefore, chromosome bands 11p15 (rhombotin) and 11p13 (Rhom-2) are consistent sites of chromosome translocation in T-cell leukemia, with the 11p15 target more rarely involved. |
| S12 | 1577-1695 | Sentence | denotes | The results define the rhombotin gene family as a class of T-cell oncogenes with duplicated cysteine-rich LIM domains. |
genia-medco-coref
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| C1 | 0-20 | NP | denotes | The rhombotin family |
| C3 | 136-141 | NP | denotes | 11p15 |
| C4 | 146-151 | NP | denotes | 11p13 |
| C2 | 118-151 | NP | denotes | human chromosomes 11p15 and 11p13 |
| C5 | 229-262 | NP | denotes | human chromosome 11 at band 11p15 |
| C6 | 272-290 | NP | denotes | the rhombotin gene |
| C7 | 292-301 | NP | denotes | This gene |
| C8 | 365-376 | NP | denotes | LIM domains |
| C9 | 378-383 | NP | denotes | which |
| C10 | 484-502 | NP | denotes | the rhombotin gene |
| C11 | 527-539 | NP | denotes | One of these |
| C12 | 552-558 | NP | denotes | Rhom-2 |
| C13 | 574-607 | NP | denotes | human chromosome 11 at band 11p13 |
| C14 | 708-713 | NP | denotes | 11p13 |
| C15 | 730-745 | NP | denotes | the Rhom-2 gene |
| C16 | 801-810 | NP | denotes | rhombotin |
| C17 | 823-855 | NP | denotes | tandem cysteine-rich LIM domains |
| C18 | 857-868 | NP | denotes | Rhom-2 mRNA |
| C19 | 1010-1024 | NP | denotes | The other gene |
| C20 | 1037-1043 | NP | denotes | Rhom-3 |
| C21 | 1133-1148 | NP | denotes | the Rhom-2 gene |
| C22 | 1250-1268 | NP | denotes | the rhombotin gene |
| C23 | 1410-1463 | NP | denotes | chromosome bands 11p15 (rhombotin) and 11p13 (Rhom-2) |
| C24 | 1542-1547 | NP | denotes | 11p15 |
| C25 | 1596-1621 | NP | denotes | the rhombotin gene family |
| C26 | 1669-1694 | NP | denotes | cysteine-rich LIM domains |
| R1 | C5 | C2 | coref-other | human chromosome 11 at band 11p15,human chromosomes 11p15 and 11p13 |
| R2 | C7 | C6 | coref-ident | This gene,the rhombotin gene |
| R3 | C9 | C8 | coref-relat | which,LIM domains |
| R4 | C10 | C6 | coref-ident | the rhombotin gene,the rhombotin gene |
| R5 | C12 | C11 | coref-appos | Rhom-2,One of these |
| R6 | C13 | C2 | coref-other | human chromosome 11 at band 11p13,human chromosomes 11p15 and 11p13 |
| R7 | C14 | C4 | coref-ident | 11p13,11p13 |
| R8 | C15 | C12 | coref-ident | the Rhom-2 gene,Rhom-2 |
| R9 | C16 | C10 | coref-ident | rhombotin,the rhombotin gene |
| R10 | C17 | C8 | coref-ident | tandem cysteine-rich LIM domains,LIM domains |
| R11 | C18 | C12 | coref-other | Rhom-2 mRNA,Rhom-2 |
| R12 | C20 | C19 | coref-appos | Rhom-3,The other gene |
| R13 | C21 | C15 | coref-ident | the Rhom-2 gene,the Rhom-2 gene |
| R14 | C22 | C16 | coref-ident | the rhombotin gene,rhombotin |
| R15 | C23 | C2 | coref-other | chromosome bands 11p15 (rhombotin) and 11p13 (Rhom-2),human chromosomes 11p15 and 11p13 |
| R16 | C24 | C3 | coref-ident | 11p15,11p15 |
| R17 | C25 | C1 | coref-ident | the rhombotin gene family,The rhombotin family |
| R18 | C26 | C17 | coref-ident | cysteine-rich LIM domains,tandem cysteine-rich LIM domains |
GENIAcorpus
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 4-20 | DNA_family_or_group | denotes | rhombotin family |
| T2 | 24-32 | amino_acid_monomer | denotes | cysteine |
| T3 | 93-114 | DNA_domain_or_region | denotes | T-cell translocations |
| T4 | 155-180 | other_name | denotes | chromosomal translocation |
| T5 | 186-201 | other_name | denotes | T-cell leukemia |
| T6 | 216-225 | DNA_domain_or_region | denotes | short arm |
| T7 | 229-248 | DNA_molecule | denotes | human chromosome 11 |
| T8 | 252-262 | DNA_domain_or_region | denotes | band 11p15 |
| T9 | 276-290 | DNA_domain_or_region | denotes | rhombotin gene |
| T10 | 336-344 | amino_acid_monomer | denotes | cysteine |
| T11 | 365-376 | protein_domain_or_region | denotes | LIM domains |
| T12 | 401-422 | protein_family_or_group | denotes | zinc-binding proteins |
| T13 | 430-449 | protein_domain_or_region | denotes | iron-sulfur centers |
| T14 | 453-464 | protein_molecule | denotes | ferredoxins |
| T15 | 488-502 | DNA_domain_or_region | denotes | rhombotin gene |
| T16 | 552-558 | DNA_domain_or_region | denotes | Rhom-2 |
| T17 | 574-593 | DNA_molecule | denotes | human chromosome 11 |
| T18 | 597-607 | DNA_domain_or_region | denotes | band 11p13 |
| T19 | 628-667 | DNA_domain_or_region | denotes | T-cell leukemia-specific translocations |
| T20 | 708-713 | DNA_domain_or_region | denotes | 11p13 |
| T21 | 734-740 | DNA_domain_or_region | denotes | Rhom-2 |
| T22 | 801-810 | DNA_domain_or_region | denotes | rhombotin |
| T23 | 823-829 | DNA_domain_or_region | denotes | tandem |
| T24 | 830-838 | amino_acid_monomer | denotes | cysteine |
| T25 | 844-855 | protein_domain_or_region | denotes | LIM domains |
| T26 | 857-863 | DNA_domain_or_region | denotes | Rhom-2 |
| T27 | 885-908 | other_name | denotes | early mouse development |
| T28 | 912-934 | body_part | denotes | central nervous system |
| T29 | 936-940 | body_part | denotes | lung |
| T30 | 942-948 | body_part | denotes | kidney |
| T31 | 950-955 | body_part | denotes | liver |
| T32 | 961-967 | body_part | denotes | spleen |
| T33 | 1002-1008 | body_part | denotes | thymus |
| T34 | 1037-1043 | DNA_domain_or_region | denotes | Rhom-3 |
| T35 | 1102-1112 | DNA_domain_or_region | denotes | LIM domain |
| T36 | 1116-1125 | DNA_domain_or_region | denotes | rhombotin |
| T37 | 1137-1143 | DNA_domain_or_region | denotes | Rhom-2 |
| T38 | 1174-1192 | other_name | denotes | chromosomal damage |
| T39 | 1196-1209 | cell_type | denotes | T-cell tumors |
| T40 | 1254-1263 | DNA_domain_or_region | denotes | rhombotin |
| T41 | 1326-1335 | DNA_domain_or_region | denotes | rhombotin |
| T42 | 1410-1432 | DNA_domain_or_region | denotes | chromosome bands 11p15 |
| T43 | 1434-1443 | DNA_domain_or_region | denotes | rhombotin |
| T44 | 1449-1454 | DNA_domain_or_region | denotes | 11p13 |
| T45 | 1456-1462 | DNA_domain_or_region | denotes | Rhom-2 |
| T46 | 1516-1531 | other_name | denotes | T-cell leukemia |
| T47 | 1542-1554 | DNA_domain_or_region | denotes | 11p15 target |
| T48 | 1600-1609 | DNA_domain_or_region | denotes | rhombotin |
| T49 | 1636-1652 | DNA_family_or_group | denotes | T-cell oncogenes |
| T50 | 1669-1677 | amino_acid_monomer | denotes | cysteine |
| T51 | 1683-1694 | protein_domain_or_region | denotes | LIM domains |