PubMed:20335937 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/20335937","sourcedb":"PubMed","sourceid":"20335937","text":"A new flavone C-glycoside from Clematis rehderiana.\nA new flavone C-glycoside, isovitexin 6''-O-E-p-coumarate (1) and two known flavonoid glycosides--quercetin 3-O-beta-D-glucuronopyranoside (2) and isoorientin (3)--were isolated from an ethanol extract of aerial parts of Clematis rehderiana. Their structures were determined by spectroscopic methods. The antioxidant effects of the two flavone C-glycosides were evaluated by both the MTT and DPPH assays. Compound 1 showed potent activities against H2O2-induced impairment in PC12 cells within the concentration range tested, whereas compound 3 scavenged DPPH radical strongly, with an IC50 value of 13.5 microM.","tracks":[{"project":"LitCoin-PubTator-for-Tuning","denotations":[{"id":"2","span":{"begin":6,"end":25},"obj":"ChemicalEntity"},{"id":"3","span":{"begin":31,"end":50},"obj":"OrganismTaxon"},{"id":"16","span":{"begin":58,"end":77},"obj":"ChemicalEntity"},{"id":"17","span":{"begin":79,"end":109},"obj":"ChemicalEntity"},{"id":"18","span":{"begin":128,"end":150},"obj":"ChemicalEntity"},{"id":"19","span":{"begin":162,"end":168},"obj":"OrganismTaxon"},{"id":"20","span":{"begin":199,"end":210},"obj":"ChemicalEntity"},{"id":"21","span":{"begin":238,"end":245},"obj":"ChemicalEntity"},{"id":"22","span":{"begin":273,"end":292},"obj":"OrganismTaxon"},{"id":"23","span":{"begin":388,"end":408},"obj":"ChemicalEntity"},{"id":"24","span":{"begin":436,"end":439},"obj":"ChemicalEntity"},{"id":"25","span":{"begin":444,"end":448},"obj":"ChemicalEntity"},{"id":"26","span":{"begin":501,"end":505},"obj":"ChemicalEntity"},{"id":"27","span":{"begin":607,"end":619},"obj":"ChemicalEntity"}],"attributes":[{"id":"A3","pred":"tao:has_database_id","subj":"3","obj":"Tax:3453"},{"id":"A19","pred":"tao:has_database_id","subj":"19","obj":"Tax:95145"},{"id":"A20","pred":"tao:has_database_id","subj":"20","obj":"MESH:C057912"},{"id":"A21","pred":"tao:has_database_id","subj":"21","obj":"MESH:D000431"},{"id":"A22","pred":"tao:has_database_id","subj":"22","obj":"Tax:3453"},{"id":"A24","pred":"tao:has_database_id","subj":"24","obj":"MESH:C070243"},{"id":"A25","pred":"tao:has_database_id","subj":"25","obj":"MESH:C004931"},{"id":"A26","pred":"tao:has_database_id","subj":"26","obj":"MESH:D006861"},{"subj":"2","pred":"source","obj":"LitCoin-PubTator-for-Tuning"},{"subj":"3","pred":"source","obj":"LitCoin-PubTator-for-Tuning"},{"subj":"16","pred":"source","obj":"LitCoin-PubTator-for-Tuning"},{"subj":"17","pred":"source","obj":"LitCoin-PubTator-for-Tuning"},{"subj":"18","pred":"source","obj":"LitCoin-PubTator-for-Tuning"},{"subj":"19","pred":"source","obj":"LitCoin-PubTator-for-Tuning"},{"subj":"20","pred":"source","obj":"LitCoin-PubTator-for-Tuning"},{"subj":"21","pred":"source","obj":"LitCoin-PubTator-for-Tuning"},{"subj":"22","pred":"source","obj":"LitCoin-PubTator-for-Tuning"},{"subj":"23","pred":"source","obj":"LitCoin-PubTator-for-Tuning"},{"subj":"24","pred":"source","obj":"LitCoin-PubTator-for-Tuning"},{"subj":"25","pred":"source","obj":"LitCoin-PubTator-for-Tuning"},{"subj":"26","pred":"source","obj":"LitCoin-PubTator-for-Tuning"},{"subj":"27","pred":"source","obj":"LitCoin-PubTator-for-Tuning"}]},{"project":"LitCoin-PubTator_CellLine","denotations":[{"id":"T1","span":{"begin":528,"end":532},"obj":"CellLine"}],"attributes":[{"id":"A1","pred":"cellosaurus_accession_id","subj":"T1","obj":"CVCL_0481"},{"id":"A2","pred":"cellosaurus_accession_id","subj":"T1","obj":"CVCL_S979"},{"subj":"T1","pred":"source","obj":"LitCoin-PubTator_CellLine"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCoin-PubTator-for-Tuning","color":"#ec93ba","default":true},{"id":"LitCoin-PubTator_CellLine","color":"#93d4ec"}]}]}}