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sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-75 Sentence denotes Molecular characterization of the cis-prenyltransferase of Giardia lamblia.
TextSentencer_T2 76-275 Sentence denotes Giardia lamblia, the protist that causes diarrhea, makes an Asn-linked-glycan (N-glycan) precursor that contains just two sugars (GlcNAc(2)) attached by a pyrophosphate linkage to a polyprenol lipid.
TextSentencer_T3 276-673 Sentence denotes Because the candidate cis-prenyltransferase of Giardia appears to be more similar to bacterial enzymes than to those of most eukaryotes and because Giardia is missing a candidate dolichol kinase (ortholog to Saccharomyces cerevisiae SEC59 gene product), we wondered how Giardia synthesizes dolichol phosphate (Dol-P), which is used to make N-glycans and glycosylphosphatidylinositol (GPI) anchors.
TextSentencer_T4 674-841 Sentence denotes Here we show that cultured Giardia makes an unsaturated polyprenyl pyrophosphate (dehydrodolichol), which contains 11 and 12 isoprene units and is reduced to dolichol.
TextSentencer_T5 842-1096 Sentence denotes The Giardia cis-prenyltransferase that we have named Gl-UPPS because the enzyme primarily synthesizes undecaprenol pyrophosphate is phylogenetically related to those of bacteria and Trypanosoma rather than to those of other protists, metazoans and fungi.
TextSentencer_T6 1097-1339 Sentence denotes In transformed Saccharomyces, the Giardia cis-prenyltransferase also makes a polyprenol containing 11 and 12 isoprene units and supports normal growth, N-glycosylation and GPI anchor synthesis of a rer2Delta, srt1Delta double-deletion mutant.
TextSentencer_T7 1340-1463 Sentence denotes Finally, despite the absence of an ortholog to SEC59, Giardia has cytidine triphosphate-dependent dolichol kinase activity.
TextSentencer_T8 1464-1655 Sentence denotes These results suggest that the synthetic pathway for Dol-P is conserved in Giardia, even if some of the important enzymes are different from those of higher eukaryotes or remain unidentified.
T1 0-75 Sentence denotes Molecular characterization of the cis-prenyltransferase of Giardia lamblia.
T2 76-275 Sentence denotes Giardia lamblia, the protist that causes diarrhea, makes an Asn-linked-glycan (N-glycan) precursor that contains just two sugars (GlcNAc(2)) attached by a pyrophosphate linkage to a polyprenol lipid.
T3 276-673 Sentence denotes Because the candidate cis-prenyltransferase of Giardia appears to be more similar to bacterial enzymes than to those of most eukaryotes and because Giardia is missing a candidate dolichol kinase (ortholog to Saccharomyces cerevisiae SEC59 gene product), we wondered how Giardia synthesizes dolichol phosphate (Dol-P), which is used to make N-glycans and glycosylphosphatidylinositol (GPI) anchors.
T4 674-841 Sentence denotes Here we show that cultured Giardia makes an unsaturated polyprenyl pyrophosphate (dehydrodolichol), which contains 11 and 12 isoprene units and is reduced to dolichol.
T5 842-1096 Sentence denotes The Giardia cis-prenyltransferase that we have named Gl-UPPS because the enzyme primarily synthesizes undecaprenol pyrophosphate is phylogenetically related to those of bacteria and Trypanosoma rather than to those of other protists, metazoans and fungi.
T6 1097-1339 Sentence denotes In transformed Saccharomyces, the Giardia cis-prenyltransferase also makes a polyprenol containing 11 and 12 isoprene units and supports normal growth, N-glycosylation and GPI anchor synthesis of a rer2Delta, srt1Delta double-deletion mutant.
T7 1340-1463 Sentence denotes Finally, despite the absence of an ortholog to SEC59, Giardia has cytidine triphosphate-dependent dolichol kinase activity.
T8 1464-1655 Sentence denotes These results suggest that the synthetic pathway for Dol-P is conserved in Giardia, even if some of the important enzymes are different from those of higher eukaryotes or remain unidentified.
T1 0-75 Sentence denotes Molecular characterization of the cis-prenyltransferase of Giardia lamblia.
T2 76-275 Sentence denotes Giardia lamblia, the protist that causes diarrhea, makes an Asn-linked-glycan (N-glycan) precursor that contains just two sugars (GlcNAc(2)) attached by a pyrophosphate linkage to a polyprenol lipid.
T3 276-673 Sentence denotes Because the candidate cis-prenyltransferase of Giardia appears to be more similar to bacterial enzymes than to those of most eukaryotes and because Giardia is missing a candidate dolichol kinase (ortholog to Saccharomyces cerevisiae SEC59 gene product), we wondered how Giardia synthesizes dolichol phosphate (Dol-P), which is used to make N-glycans and glycosylphosphatidylinositol (GPI) anchors.
T4 674-841 Sentence denotes Here we show that cultured Giardia makes an unsaturated polyprenyl pyrophosphate (dehydrodolichol), which contains 11 and 12 isoprene units and is reduced to dolichol.
T5 842-1096 Sentence denotes The Giardia cis-prenyltransferase that we have named Gl-UPPS because the enzyme primarily synthesizes undecaprenol pyrophosphate is phylogenetically related to those of bacteria and Trypanosoma rather than to those of other protists, metazoans and fungi.
T6 1097-1339 Sentence denotes In transformed Saccharomyces, the Giardia cis-prenyltransferase also makes a polyprenol containing 11 and 12 isoprene units and supports normal growth, N-glycosylation and GPI anchor synthesis of a rer2Delta, srt1Delta double-deletion mutant.
T7 1340-1463 Sentence denotes Finally, despite the absence of an ortholog to SEC59, Giardia has cytidine triphosphate-dependent dolichol kinase activity.
T8 1464-1655 Sentence denotes These results suggest that the synthetic pathway for Dol-P is conserved in Giardia, even if some of the important enzymes are different from those of higher eukaryotes or remain unidentified.

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 117-125 HP_0002014 denotes diarrhea

GlycoBiology-PACDB

Id Subject Object Predicate Lexical cue
_T1 484-508 http://acgg.asia/db/diseases/pacdb/lec?ids=LEC297 denotes Saccharomyces cerevisiae

GlycoBiology-FMA

Id Subject Object Predicate Lexical cue
_T1 198-204 FMAID:196724 denotes sugars
_T2 269-274 FMAID:165448 denotes lipid
_T3 269-274 FMAID:67264 denotes lipid
_T4 515-519 FMAID:198663 denotes gene
_T5 630-658 FMAID:85436 denotes glycosylphosphatidylinositol
_T6 630-658 FMAID:82806 denotes glycosylphosphatidylinositol
_T7 630-658 FMAID:199790 denotes glycosylphosphatidylinositol
_T8 630-658 FMAID:196801 denotes glycosylphosphatidylinositol

uniprot-human

Id Subject Object Predicate Lexical cue
T1 455-470 http://www.uniprot.org/uniprot/Q9UPQ8 denotes dolichol kinase
T2 1438-1453 http://www.uniprot.org/uniprot/Q9UPQ8 denotes dolichol kinase
T3 660-663 http://www.uniprot.org/uniprot/P06744 denotes GPI
T4 1269-1272 http://www.uniprot.org/uniprot/P06744 denotes GPI

uniprot-mouse

Id Subject Object Predicate Lexical cue
T1 34-37 http://www.uniprot.org/uniprot/Q62225 denotes cis
T2 298-301 http://www.uniprot.org/uniprot/Q62225 denotes cis
T3 854-857 http://www.uniprot.org/uniprot/Q62225 denotes cis
T4 1139-1142 http://www.uniprot.org/uniprot/Q62225 denotes cis
T5 136-139 http://www.uniprot.org/uniprot/Q61024 denotes Asn
T6 455-470 http://www.uniprot.org/uniprot/Q8R2Y3 denotes dolichol kinase
T7 1438-1453 http://www.uniprot.org/uniprot/Q8R2Y3 denotes dolichol kinase
T8 660-663 http://www.uniprot.org/uniprot/Q8C675 denotes GPI
T9 1269-1272 http://www.uniprot.org/uniprot/Q8C675 denotes GPI

GlycoBiology-NCBITAXON

Id Subject Object Predicate Lexical cue
T1 34-37 http://purl.bioontology.org/ontology/NCBITAXON/245896 denotes cis
T2 59-66 http://purl.bioontology.org/ontology/NCBITAXON/5740 denotes Giardia
T3 59-74 http://purl.bioontology.org/ontology/NCBITAXON/29255 denotes Giardia lamblia
T4 76-83 http://purl.bioontology.org/ontology/NCBITAXON/5740 denotes Giardia
T5 76-91 http://purl.bioontology.org/ontology/NCBITAXON/29255 denotes Giardia lamblia
T6 298-301 http://purl.bioontology.org/ontology/NCBITAXON/245896 denotes cis
T7 323-330 http://purl.bioontology.org/ontology/NCBITAXON/5740 denotes Giardia
T8 401-411 http://purl.bioontology.org/ontology/NCBITAXON/2759 denotes eukaryotes
T9 424-431 http://purl.bioontology.org/ontology/NCBITAXON/5740 denotes Giardia
T10 484-497 http://purl.bioontology.org/ontology/NCBITAXON/4895 denotes Saccharomyces
T11 484-497 http://purl.bioontology.org/ontology/NCBITAXON/4930 denotes Saccharomyces
T12 484-497 http://purl.bioontology.org/ontology/NCBITAXON/4891 denotes Saccharomyces
T13 484-497 http://purl.bioontology.org/ontology/NCBITAXON/36034 denotes Saccharomyces
T14 546-553 http://purl.bioontology.org/ontology/NCBITAXON/5740 denotes Giardia
T15 701-708 http://purl.bioontology.org/ontology/NCBITAXON/5740 denotes Giardia
T16 846-853 http://purl.bioontology.org/ontology/NCBITAXON/5740 denotes Giardia
T17 854-857 http://purl.bioontology.org/ontology/NCBITAXON/245896 denotes cis
T18 991-998 http://purl.bioontology.org/ontology/NCBITAXON/353209 denotes related
T19 1011-1019 http://purl.bioontology.org/ontology/NCBITAXON/629395 denotes bacteria
T20 1011-1019 http://purl.bioontology.org/ontology/NCBITAXON/2 denotes bacteria
T21 1024-1035 http://purl.bioontology.org/ontology/NCBITAXON/71805 denotes Trypanosoma
T22 1024-1035 http://purl.bioontology.org/ontology/NCBITAXON/5690 denotes Trypanosoma
T23 1024-1035 http://purl.bioontology.org/ontology/NCBITAXON/56869 denotes Trypanosoma
T24 1024-1035 http://purl.bioontology.org/ontology/NCBITAXON/5654 denotes Trypanosoma
T25 1112-1125 http://purl.bioontology.org/ontology/NCBITAXON/4891 denotes Saccharomyces
T26 1112-1125 http://purl.bioontology.org/ontology/NCBITAXON/4930 denotes Saccharomyces
T27 1112-1125 http://purl.bioontology.org/ontology/NCBITAXON/36034 denotes Saccharomyces
T28 1112-1125 http://purl.bioontology.org/ontology/NCBITAXON/4895 denotes Saccharomyces
T29 1131-1138 http://purl.bioontology.org/ontology/NCBITAXON/5740 denotes Giardia
T30 1139-1142 http://purl.bioontology.org/ontology/NCBITAXON/245896 denotes cis
T31 1394-1401 http://purl.bioontology.org/ontology/NCBITAXON/5740 denotes Giardia
T32 1539-1546 http://purl.bioontology.org/ontology/NCBITAXON/5740 denotes Giardia
T33 1621-1631 http://purl.bioontology.org/ontology/NCBITAXON/2759 denotes eukaryotes

GO-BP

Id Subject Object Predicate Lexical cue
T1 1241-1247 http://purl.obolibrary.org/obo/GO_0040007 denotes growth
T2 1251-1264 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation
T3 1269-1289 http://purl.obolibrary.org/obo/GO_0006506 denotes GPI anchor synthesis
T4 1280-1289 http://purl.obolibrary.org/obo/GO_0009058 denotes synthesis
T5 1438-1462 http://purl.obolibrary.org/obo/GO_0004168 denotes dolichol kinase activity
T6 1447-1462 http://purl.obolibrary.org/obo/GO_0033674 denotes kinase activity
T7 1447-1462 http://purl.obolibrary.org/obo/GO_0016301 denotes kinase activity

GO-MF

Id Subject Object Predicate Lexical cue
T1 665-672 http://purl.obolibrary.org/obo/GO_0043495 denotes anchors
T2 1273-1279 http://purl.obolibrary.org/obo/GO_0043495 denotes anchor

Allie

Id Subject Object Predicate Lexical cue
SS1_20308470_2_0 566-584 expanded denotes dolichol phosphate
SS2_20308470_2_0 586-591 abbr denotes Dol-P
SS1_20308470_2_1 630-658 expanded denotes glycosylphosphatidylinositol
SS2_20308470_2_1 660-663 abbr denotes GPI
AE1_20308470_2_0 SS1_20308470_2_0 SS2_20308470_2_0 abbreviatedTo dolichol phosphate,Dol-P
AE1_20308470_2_1 SS1_20308470_2_1 SS2_20308470_2_1 abbreviatedTo glycosylphosphatidylinositol,GPI

EDAM-topics

Id Subject Object Predicate Lexical cue
T1 245-252 http://edamontology.org/topic_0102 denotes linkage
T2 269-274 http://edamontology.org/topic_0153 denotes lipid
T3 401-411 http://edamontology.org/topic_2818 denotes eukaryotes
T4 974-990 http://edamontology.org/topic_3293 denotes phylogenetically
T5 1090-1095 http://edamontology.org/topic_0782 denotes fungi
T6 1505-1512 http://edamontology.org/topic_0602 denotes pathway
T7 1621-1631 http://edamontology.org/topic_2818 denotes eukaryotes

EDAM-DFO

Id Subject Object Predicate Lexical cue
T1 515-527 http://edamontology.org/data_0896 denotes gene product
T2 889-894 http://edamontology.org/data_2099 denotes named
T3 974-998 http://edamontology.org/data_1438 denotes phylogenetically related
T4 1234-1240 http://edamontology.org/operation_3435 denotes normal
T5 1505-1512 http://edamontology.org/data_2600 denotes pathway
T6 1642-1654 http://edamontology.org/data_1104 denotes unidentified

NGLY1-deficiency

Id Subject Object Predicate Lexical cue
PD-NGLY1-deficiency-B_T1 206-212 chem:24139 denotes GlcNAc

GlycoBiology-Motifs

Id Subject Object Predicate Lexical cue
T1 155-163 http://rdf.glycoinfo.org/glycan/G00027MO denotes N-glycan
T2 616-625 http://rdf.glycoinfo.org/glycan/G00027MO denotes N-glycans
T3 660-672 http://rdf.glycoinfo.org/glycan/G00045MO denotes GPI) anchors
T4 1269-1279 http://rdf.glycoinfo.org/glycan/G00045MO denotes GPI anchor

GlyTouCan-IUPAC

Id Subject Object Predicate Lexical cue
GlycanIUPAC_T1 198-204 "http://rdf.glycoinfo.org/glycan/G59665TO" denotes sugars
GlycanIUPAC_T2 198-204 "http://rdf.glycoinfo.org/glycan/G32915EI" denotes sugars
GlycanIUPAC_T3 198-204 "http://rdf.glycoinfo.org/glycan/G60625TS" denotes sugars
GlycanIUPAC_T4 206-212 "http://rdf.glycoinfo.org/glycan/G26693XF" denotes GlcNAc
GlycanIUPAC_T5 206-212 "http://rdf.glycoinfo.org/glycan/G01864SU" denotes GlcNAc
GlycanIUPAC_T6 206-212 "http://rdf.glycoinfo.org/glycan/G17605FD" denotes GlcNAc
GlycanIUPAC_T7 206-212 "http://rdf.glycoinfo.org/glycan/G41950LU" denotes GlcNAc
GlycanIUPAC_T8 206-212 "http://rdf.glycoinfo.org/glycan/G57195RJ" denotes GlcNAc
GlycanIUPAC_T9 206-212 "http://rdf.glycoinfo.org/glycan/G85391SA" denotes GlcNAc
GlycanIUPAC_T10 206-212 "http://rdf.glycoinfo.org/glycan/G89565QL" denotes GlcNAc
GlycanIUPAC_T11 206-212 "http://rdf.glycoinfo.org/glycan/G80869MR" denotes GlcNAc
GlycanIUPAC_T12 206-212 "http://rdf.glycoinfo.org/glycan/G55978NL" denotes GlcNAc
GlycanIUPAC_T13 206-212 "http://rdf.glycoinfo.org/glycan/G54644LT" denotes GlcNAc
GlycanIUPAC_T14 206-212 "http://rdf.glycoinfo.org/glycan/G25694UG" denotes GlcNAc
GlycanIUPAC_T15 206-212 "http://rdf.glycoinfo.org/glycan/G25126RB" denotes GlcNAc
GlycanIUPAC_T16 206-212 "http://rdf.glycoinfo.org/glycan/G51848AD" denotes GlcNAc
GlycanIUPAC_T17 206-212 "http://rdf.glycoinfo.org/glycan/G94667GM" denotes GlcNAc
GlycanIUPAC_T18 206-212 "http://rdf.glycoinfo.org/glycan/G30124BO" denotes GlcNAc
GlycanIUPAC_T19 206-212 "http://rdf.glycoinfo.org/glycan/G82777EZ" denotes GlcNAc
GlycanIUPAC_T20 206-212 "http://rdf.glycoinfo.org/glycan/G10151YZ" denotes GlcNAc
GlycanIUPAC_T21 206-212 "http://rdf.glycoinfo.org/glycan/G17585ZM" denotes GlcNAc
GlycanIUPAC_T22 206-212 "http://rdf.glycoinfo.org/glycan/G04411CJ" denotes GlcNAc
GlycanIUPAC_T23 206-212 "http://rdf.glycoinfo.org/glycan/G38254HJ" denotes GlcNAc
GlycanIUPAC_T24 206-212 "http://rdf.glycoinfo.org/glycan/G75188FS" denotes GlcNAc
GlycanIUPAC_T25 206-212 "http://rdf.glycoinfo.org/glycan/G70374VG" denotes GlcNAc
GlycanIUPAC_T26 206-212 "http://rdf.glycoinfo.org/glycan/G45176LJ" denotes GlcNAc
GlycanIUPAC_T27 206-212 "http://rdf.glycoinfo.org/glycan/G30874VW" denotes GlcNAc
GlycanIUPAC_T28 206-212 "http://rdf.glycoinfo.org/glycan/G69333MI" denotes GlcNAc
GlycanIUPAC_T29 206-212 "http://rdf.glycoinfo.org/glycan/G10676XO" denotes GlcNAc
GlycanIUPAC_T30 206-212 "http://rdf.glycoinfo.org/glycan/G14843DJ" denotes GlcNAc
GlycanIUPAC_T31 206-212 "http://rdf.glycoinfo.org/glycan/G47546FR" denotes GlcNAc
GlycanIUPAC_T32 206-212 "http://rdf.glycoinfo.org/glycan/G73695ZM" denotes GlcNAc
GlycanIUPAC_T33 206-212 "http://rdf.glycoinfo.org/glycan/G31923TJ" denotes GlcNAc
GlycanIUPAC_T34 206-212 "http://rdf.glycoinfo.org/glycan/G60519EP" denotes GlcNAc
GlycanIUPAC_T35 206-212 "http://rdf.glycoinfo.org/glycan/G07933IA" denotes GlcNAc
GlycanIUPAC_T36 206-212 "http://rdf.glycoinfo.org/glycan/G40745NH" denotes GlcNAc
GlycanIUPAC_T37 206-212 "http://rdf.glycoinfo.org/glycan/G54496YV" denotes GlcNAc
GlycanIUPAC_T38 206-212 "http://rdf.glycoinfo.org/glycan/G62953SQ" denotes GlcNAc
GlycanIUPAC_T39 206-212 "http://rdf.glycoinfo.org/glycan/G70070AY" denotes GlcNAc
GlycanIUPAC_T40 206-212 "http://rdf.glycoinfo.org/glycan/G78792WC" denotes GlcNAc
GlycanIUPAC_T41 206-212 "http://rdf.glycoinfo.org/glycan/G25238AV" denotes GlcNAc
GlycanIUPAC_T42 206-212 "http://rdf.glycoinfo.org/glycan/G40510DP" denotes GlcNAc
GlycanIUPAC_T43 206-212 "http://rdf.glycoinfo.org/glycan/G61120TK" denotes GlcNAc
GlycanIUPAC_T44 206-212 "http://rdf.glycoinfo.org/glycan/G41342KV" denotes GlcNAc
GlycanIUPAC_T45 206-212 "http://rdf.glycoinfo.org/glycan/G90703NA" denotes GlcNAc
GlycanIUPAC_T46 206-212 "http://rdf.glycoinfo.org/glycan/G01591HR" denotes GlcNAc
GlycanIUPAC_T47 206-212 "http://rdf.glycoinfo.org/glycan/G56520XN" denotes GlcNAc
GlycanIUPAC_T48 206-212 "http://rdf.glycoinfo.org/glycan/G81830JX" denotes GlcNAc

mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 59-66 Disease denotes Giardia http://purl.obolibrary.org/obo/MONDO_0001103
T2 76-83 Disease denotes Giardia http://purl.obolibrary.org/obo/MONDO_0001103
T3 117-125 Disease denotes diarrhea http://purl.obolibrary.org/obo/MONDO_0001673
T4 323-330 Disease denotes Giardia http://purl.obolibrary.org/obo/MONDO_0001103
T5 424-431 Disease denotes Giardia http://purl.obolibrary.org/obo/MONDO_0001103
T6 546-553 Disease denotes Giardia http://purl.obolibrary.org/obo/MONDO_0001103
T7 701-708 Disease denotes Giardia http://purl.obolibrary.org/obo/MONDO_0001103
T8 846-853 Disease denotes Giardia http://purl.obolibrary.org/obo/MONDO_0001103
T9 1131-1138 Disease denotes Giardia http://purl.obolibrary.org/obo/MONDO_0001103
T10 1394-1401 Disease denotes Giardia http://purl.obolibrary.org/obo/MONDO_0001103
T11 1539-1546 Disease denotes Giardia http://purl.obolibrary.org/obo/MONDO_0001103

GlyCosmos15-HP

Id Subject Object Predicate Lexical cue hp_id
T1 117-125 Phenotype denotes diarrhea HP:0002014

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 59-74 OrganismTaxon denotes Giardia lamblia 5741
T2 76-91 OrganismTaxon denotes Giardia lamblia 5741
T3 323-330 OrganismTaxon denotes Giardia 5740
T4 401-411 OrganismTaxon denotes eukaryotes 2759
T5 424-431 OrganismTaxon denotes Giardia 5740
T6 484-508 OrganismTaxon denotes Saccharomyces cerevisiae 4932
T7 546-553 OrganismTaxon denotes Giardia 5740
T8 701-708 OrganismTaxon denotes Giardia 5740
T9 846-853 OrganismTaxon denotes Giardia 5740
T10 1011-1019 OrganismTaxon denotes bacteria 2|629395
T12 1024-1035 OrganismTaxon denotes Trypanosoma 5690
T13 1090-1095 OrganismTaxon denotes fungi 4751
T14 1112-1125 OrganismTaxon denotes Saccharomyces 4930
T15 1131-1138 OrganismTaxon denotes Giardia 5740
T16 1394-1401 OrganismTaxon denotes Giardia 5740
T17 1539-1546 OrganismTaxon denotes Giardia 5740
T18 1621-1631 OrganismTaxon denotes eukaryotes 2759