PubMed:20129423
Annnotations
LitCoin-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-216 | Sentence | denotes | Fatal carbamazepine induced fulminant eosinophilic (hypersensitivity) myocarditis: emphasis on anatomical and histological characteristics, mechanisms and genetics of drug hypersensitivity and differential diagnosis. |
| T2 | 217-355 | Sentence | denotes | The most severe adverse reactions to carbamazepine have been observed in the haemopoietic system, the liver and the cardiovascular system. |
| T3 | 356-492 | Sentence | denotes | A frequently fatal, although exceptionally rare side effect of carbamazepine is necrotizing eosinophilic (hypersensitivity) myocarditis. |
| T4 | 493-587 | Sentence | denotes | We report a case of hypersensitivity myocarditis secondary to administration of carbamazepine. |
| T5 | 588-692 | Sentence | denotes | Acute hypersensitivity myocarditis was not suspected clinically, and the diagnosis was made post-mortem. |
| T6 | 693-802 | Sentence | denotes | Histology revealed diffuse infiltration of the myocardium by eosinophils and lymphocytes with myocyte damage. |
| T7 | 803-850 | Sentence | denotes | Clinically, death was due to cardiogenic shock. |
| T8 | 851-974 | Sentence | denotes | To best of our knowledge this is the second case of fatal carbamazepine induced myocarditis reported in English literature. |
LitCoin-entities
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| 7081 | 6-19 | ChemicalEntity | denotes | carbamazepine | MESH:D002220 |
| 7082 | 52-68 | DiseaseOrPhenotypicFeature | denotes | hypersensitivity | MESH:D006967 |
| 7083 | 70-81 | DiseaseOrPhenotypicFeature | denotes | myocarditis | MESH:D009205 |
| 7084 | 167-188 | DiseaseOrPhenotypicFeature | denotes | drug hypersensitivity | MESH:D004342 |
| 7085 | 254-267 | ChemicalEntity | denotes | carbamazepine | MESH:D002220 |
| 7086 | 419-432 | ChemicalEntity | denotes | carbamazepine | MESH:D002220 |
| 7087 | 462-478 | DiseaseOrPhenotypicFeature | denotes | hypersensitivity | MESH:D006967 |
| 7088 | 480-491 | DiseaseOrPhenotypicFeature | denotes | myocarditis | MESH:D009205 |
| 7089 | 513-529 | DiseaseOrPhenotypicFeature | denotes | hypersensitivity | MESH:D006967 |
| 7090 | 530-541 | DiseaseOrPhenotypicFeature | denotes | myocarditis | MESH:D009205 |
| 7091 | 573-586 | ChemicalEntity | denotes | carbamazepine | MESH:D002220 |
| 7092 | 594-610 | DiseaseOrPhenotypicFeature | denotes | hypersensitivity | MESH:D006967 |
| 7093 | 611-622 | DiseaseOrPhenotypicFeature | denotes | myocarditis | MESH:D009205 |
| 7094 | 815-820 | DiseaseOrPhenotypicFeature | denotes | death | MESH:D003643 |
| 7095 | 832-849 | DiseaseOrPhenotypicFeature | denotes | cardiogenic shock | MESH:D012770 |
| 7096 | 909-922 | ChemicalEntity | denotes | carbamazepine | MESH:D002220 |
| 7097 | 931-942 | DiseaseOrPhenotypicFeature | denotes | myocarditis | MESH:D009205 |
LitCoin_Mondo
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 70-81 | DiseaseOrPhenotypicFeature | denotes | myocarditis | 0004496 |
| T2 | 399-403 | DiseaseOrPhenotypicFeature | denotes | rare | 0021136 |
| T3 | 480-491 | DiseaseOrPhenotypicFeature | denotes | myocarditis | 0004496 |
| T4 | 530-541 | DiseaseOrPhenotypicFeature | denotes | myocarditis | 0004496 |
| T5 | 611-622 | DiseaseOrPhenotypicFeature | denotes | myocarditis | 0004496 |
| T6 | 931-942 | DiseaseOrPhenotypicFeature | denotes | myocarditis | 0004496 |
LitCoin-GeneOrGeneProduct-v0
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 20-27 | GeneOrGeneProduct | denotes | induced |
| T2 | 38-50 | GeneOrGeneProduct | denotes | eosinophilic |
| T3 | 52-68 | GeneOrGeneProduct | denotes | hypersensitivity |
| T4 | 172-188 | GeneOrGeneProduct | denotes | hypersensitivity |
| T5 | 319-324 | GeneOrGeneProduct | denotes | liver |
| T6 | 399-403 | GeneOrGeneProduct | denotes | rare |
| T7 | 404-408 | GeneOrGeneProduct | denotes | side |
| T8 | 436-447 | GeneOrGeneProduct | denotes | necrotizing |
| T9 | 448-460 | GeneOrGeneProduct | denotes | eosinophilic |
| T10 | 462-478 | GeneOrGeneProduct | denotes | hypersensitivity |
| T11 | 505-509 | GeneOrGeneProduct | denotes | case |
| T12 | 513-529 | GeneOrGeneProduct | denotes | hypersensitivity |
| T13 | 594-610 | GeneOrGeneProduct | denotes | hypersensitivity |
| T14 | 680-684 | GeneOrGeneProduct | denotes | post |
| T15 | 754-765 | GeneOrGeneProduct | denotes | eosinophils |
| T16 | 770-781 | GeneOrGeneProduct | denotes | lymphocytes |
| T17 | 795-801 | GeneOrGeneProduct | denotes | damage |
| T18 | 844-849 | GeneOrGeneProduct | denotes | shock |
| T19 | 854-858 | GeneOrGeneProduct | denotes | best |
| T20 | 895-899 | GeneOrGeneProduct | denotes | case |
| T21 | 923-930 | GeneOrGeneProduct | denotes | induced |
LitCoin-GeneOrGeneProduct-v2
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 319-324 | GeneOrGeneProduct | denotes | liver |
| T2 | 399-403 | GeneOrGeneProduct | denotes | rare |
| T3 | 404-408 | GeneOrGeneProduct | denotes | side |
| T4 | 680-684 | GeneOrGeneProduct | denotes | post |
| T5 | 754-765 | GeneOrGeneProduct | denotes | eosinophils |
| T6 | 770-781 | GeneOrGeneProduct | denotes | lymphocytes |
| T7 | 854-858 | GeneOrGeneProduct | denotes | best |
LitCoin-Disease-MeSH
| Id | Subject | Object | Predicate | Lexical cue | originalLabel |
|---|---|---|---|---|---|
| T1 | 52-68 | DiseaseOrPhenotypicFeature | denotes | hypersensitivity | D006967 |
| T2 | 70-81 | DiseaseOrPhenotypicFeature | denotes | myocarditis | D009205 |
| T3 | 167-188 | DiseaseOrPhenotypicFeature | denotes | drug hypersensitivity | D004342 |
| T4 | 462-478 | DiseaseOrPhenotypicFeature | denotes | hypersensitivity | D006967 |
| T5 | 480-491 | DiseaseOrPhenotypicFeature | denotes | myocarditis | D009205 |
| T6 | 513-529 | DiseaseOrPhenotypicFeature | denotes | hypersensitivity | D006967 |
| T7 | 530-541 | DiseaseOrPhenotypicFeature | denotes | myocarditis | D009205 |
| T8 | 594-610 | DiseaseOrPhenotypicFeature | denotes | hypersensitivity | D006967 |
| T9 | 611-622 | DiseaseOrPhenotypicFeature | denotes | myocarditis | D009205 |
| T10 | 815-820 | DiseaseOrPhenotypicFeature | denotes | death | D003643 |
| T11 | 832-849 | DiseaseOrPhenotypicFeature | denotes | cardiogenic shock | D012770 |
| T12 | 931-942 | DiseaseOrPhenotypicFeature | denotes | myocarditis | D009205 |
LitCoin-GeneOrGeneProduct-v3
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 754-765 | GeneOrGeneProduct | denotes | eosinophils |
LitCoin_Mondo_095
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 52-68 | DiseaseOrPhenotypicFeature | denotes | hypersensitivity | 0005271|0000605 |
| T3 | 70-81 | DiseaseOrPhenotypicFeature | denotes | myocarditis | 0004496 |
| T4 | 172-188 | DiseaseOrPhenotypicFeature | denotes | hypersensitivity | 0005271|0000605 |
| T6 | 462-478 | DiseaseOrPhenotypicFeature | denotes | hypersensitivity | 0005271|0000605 |
| T8 | 480-491 | DiseaseOrPhenotypicFeature | denotes | myocarditis | 0004496 |
| T9 | 513-529 | DiseaseOrPhenotypicFeature | denotes | hypersensitivity | 0005271|0000605 |
| T11 | 530-541 | DiseaseOrPhenotypicFeature | denotes | myocarditis | 0004496 |
| T12 | 594-610 | DiseaseOrPhenotypicFeature | denotes | hypersensitivity | 0005271|0000605 |
| T14 | 611-622 | DiseaseOrPhenotypicFeature | denotes | myocarditis | 0004496 |
| T15 | 931-942 | DiseaseOrPhenotypicFeature | denotes | myocarditis | 0004496 |
LitCoin-MeSH-Disease-2
| Id | Subject | Object | Predicate | Lexical cue | ID: |
|---|---|---|---|---|---|
| T1 | 52-68 | DiseaseOrPhenotypicFeature | denotes | hypersensitivity | D006967 |
| T2 | 70-81 | DiseaseOrPhenotypicFeature | denotes | myocarditis | D009205 |
| T3 | 167-188 | DiseaseOrPhenotypicFeature | denotes | drug hypersensitivity | D004342 |
| T4 | 462-478 | DiseaseOrPhenotypicFeature | denotes | hypersensitivity | D006967 |
| T5 | 480-491 | DiseaseOrPhenotypicFeature | denotes | myocarditis | D009205 |
| T6 | 513-529 | DiseaseOrPhenotypicFeature | denotes | hypersensitivity | D006967 |
| T7 | 530-541 | DiseaseOrPhenotypicFeature | denotes | myocarditis | D009205 |
| T8 | 594-610 | DiseaseOrPhenotypicFeature | denotes | hypersensitivity | D006967 |
| T9 | 611-622 | DiseaseOrPhenotypicFeature | denotes | myocarditis | D009205 |
| T10 | 815-820 | DiseaseOrPhenotypicFeature | denotes | death | D003643 |
| T11 | 832-849 | DiseaseOrPhenotypicFeature | denotes | cardiogenic shock | D012770 |
| T12 | 931-942 | DiseaseOrPhenotypicFeature | denotes | myocarditis | D009205 |
LitCoin-MONDO_bioort2019
| Id | Subject | Object | Predicate | Lexical cue | #label |
|---|---|---|---|---|---|
| T1 | 52-68 | DiseaseOrPhenotypicFeature | denotes | hypersensitivity | D006967 |
| T2 | 70-81 | DiseaseOrPhenotypicFeature | denotes | myocarditis | D009205 |
| T3 | 167-188 | DiseaseOrPhenotypicFeature | denotes | drug hypersensitivity | D004342 |
| T4 | 462-478 | DiseaseOrPhenotypicFeature | denotes | hypersensitivity | D006967 |
| T5 | 480-491 | DiseaseOrPhenotypicFeature | denotes | myocarditis | D009205 |
| T6 | 513-529 | DiseaseOrPhenotypicFeature | denotes | hypersensitivity | D006967 |
| T7 | 530-541 | DiseaseOrPhenotypicFeature | denotes | myocarditis | D009205 |
| T8 | 594-610 | DiseaseOrPhenotypicFeature | denotes | hypersensitivity | D006967 |
| T9 | 611-622 | DiseaseOrPhenotypicFeature | denotes | myocarditis | D009205 |
| T10 | 832-849 | DiseaseOrPhenotypicFeature | denotes | cardiogenic shock | D012770 |
| T11 | 931-942 | DiseaseOrPhenotypicFeature | denotes | myocarditis | D009205 |
LitCoin-Chemical-MeSH-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | ID: |
|---|---|---|---|---|---|
| T1 | 6-19 | ChemicalEntity | denotes | carbamazepine | D002220|http://purl.obolibrary.org/obo/CHEBI_3387 |
| T3 | 254-267 | ChemicalEntity | denotes | carbamazepine | D002220|http://purl.obolibrary.org/obo/CHEBI_3387 |
| T5 | 419-432 | ChemicalEntity | denotes | carbamazepine | D002220|http://purl.obolibrary.org/obo/CHEBI_3387 |
| T7 | 573-586 | ChemicalEntity | denotes | carbamazepine | D002220|http://purl.obolibrary.org/obo/CHEBI_3387 |
| T9 | 909-922 | ChemicalEntity | denotes | carbamazepine | D002220|http://purl.obolibrary.org/obo/CHEBI_3387 |
LitCoin-training-merged
| Id | Subject | Object | Predicate | Lexical cue | #label | ID: |
|---|---|---|---|---|---|---|
| T9 | 909-922 | ChemicalEntity | denotes | carbamazepine | http://purl.obolibrary.org/obo/CHEBI_3387|D002220 | |
| T7 | 573-586 | ChemicalEntity | denotes | carbamazepine | http://purl.obolibrary.org/obo/CHEBI_3387|D002220 | |
| T5 | 419-432 | ChemicalEntity | denotes | carbamazepine | http://purl.obolibrary.org/obo/CHEBI_3387|D002220 | |
| T3 | 254-267 | ChemicalEntity | denotes | carbamazepine | http://purl.obolibrary.org/obo/CHEBI_3387|D002220 | |
| T1 | 6-19 | ChemicalEntity | denotes | carbamazepine | http://purl.obolibrary.org/obo/CHEBI_3387|D002220 | |
| T80373 | 754-765 | GeneOrGeneProduct | denotes | eosinophils | ||
| T11 | 931-942 | DiseaseOrPhenotypicFeature | denotes | myocarditis | D009205 | |
| T10 | 832-849 | DiseaseOrPhenotypicFeature | denotes | cardiogenic shock | D012770 | |
| T22750 | 611-622 | DiseaseOrPhenotypicFeature | denotes | myocarditis | D009205 | |
| T8 | 594-610 | DiseaseOrPhenotypicFeature | denotes | hypersensitivity | D006967 | |
| T37882 | 530-541 | DiseaseOrPhenotypicFeature | denotes | myocarditis | D009205 | |
| T6 | 513-529 | DiseaseOrPhenotypicFeature | denotes | hypersensitivity | D006967 | |
| T5720 | 480-491 | DiseaseOrPhenotypicFeature | denotes | myocarditis | D009205 | |
| T4 | 462-478 | DiseaseOrPhenotypicFeature | denotes | hypersensitivity | D006967 | |
| T88795 | 167-188 | DiseaseOrPhenotypicFeature | denotes | drug hypersensitivity | D004342 | |
| T2 | 70-81 | DiseaseOrPhenotypicFeature | denotes | myocarditis | D009205 | |
| T7082 | 52-68 | DiseaseOrPhenotypicFeature | denotes | hypersensitivity | D006967 |
PubmedHPO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 832-849 | HP_0030149 | denotes | cardiogenic shock |
PubCasesHPO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| TI1 | 70-81 | HP:0012819 | denotes | myocarditis |
| AB1 | 480-491 | HP:0012819 | denotes | myocarditis |
| AB2 | 530-541 | HP:0012819 | denotes | myocarditis |
| AB3 | 611-622 | HP:0012819 | denotes | myocarditis |
| AB4 | 832-849 | HP:0030149 | denotes | cardiogenic shock |
| AB5 | 931-942 | HP:0012819 | denotes | myocarditis |