PubMed:20103725 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/20103725","sourcedb":"PubMed","sourceid":"20103725","source_url":"http://www.ncbi.nlm.nih.gov/pubmed/20103725","text":"Cyclooxygenase-2 inhibition for the prophylaxis and treatment of preinvasive breast cancer in a her-2/neu mouse model.\nDuctal carcinoma in situ (DCIS) is the most common form of preinvasive breast cancer. Several molecular alterations have been identified in DCIS. Among them, cyclooxygenase 2 (COX-2) overexpression has been shown in 60% to 80% of DCIS cases. Celecoxib is a nonsteroidal anti-inflammatory drug that selectively inhibits COX-2. In this study, we evaluated whether COX-2 inhibition by celecoxib can reduce the incidence of preinvasive breast cancer and its progression to invasive breast cancer in a mouse model exhibiting a similar phenotype to human solid-pattern DCIS. We have used the mouse model mouse mammary tumor virus (MMTV)-Neu to investigate this possibility. These mice carry a rat Her-2/Neu transgene and are known to develop DCIS-like lesions. Our results showed that celecoxib (500 ppm) given as prophylaxis was neither able to prevent tumor development nor delay tumor appearance compared with untreated mice. Furthermore, when the drug was given early in tumorigenesis, it did not reduce the progression of preinvasive to invasive tumors nor prevent lung metastasis. Reduction of prostaglandin levels was, however, achieved in mammary tumors of treated mice. In addition, celecoxib treatment caused an increase in apoptosis and decreased vascular endothelial growth factor expression in treated animals. Our results contrast with some previously published studies and highlight the complexity of the relationship between COX-2 and breast cancer.","tracks":[{"project":"c_corpus","denotations":[{"id":"T2","span":{"begin":0,"end":16},"obj":"O62725"},{"id":"T3","span":{"begin":0,"end":16},"obj":"Q05769"},{"id":"T4","span":{"begin":0,"end":16},"obj":"P35355"},{"id":"T5","span":{"begin":0,"end":16},"obj":"P79208"},{"id":"T6","span":{"begin":0,"end":16},"obj":"P35354"},{"id":"T7","span":{"begin":0,"end":16},"obj":"O02768"},{"id":"T8","span":{"begin":0,"end":16},"obj":"PR:000013428"},{"id":"T9","span":{"begin":0,"end":16},"obj":"P27607"},{"id":"T10","span":{"begin":0,"end":16},"obj":"O19183"},{"id":"T11","span":{"begin":0,"end":16},"obj":"O62698"},{"id":"T12","span":{"begin":0,"end":16},"obj":"P70682"},{"id":"T13","span":{"begin":0,"end":16},"obj":"D051546"},{"id":"T14","span":{"begin":77,"end":83},"obj":"UBERON:0000310"},{"id":"T15","span":{"begin":77,"end":90},"obj":"D001943"},{"id":"T16","span":{"begin":77,"end":90},"obj":"D001943"},{"id":"T17","span":{"begin":94,"end":101},"obj":"CVCL_J973"},{"id":"T18","span":{"begin":96,"end":101},"obj":"PR:P04626"},{"id":"T19","span":{"begin":96,"end":101},"obj":"PR:000002082"},{"id":"T20","span":{"begin":96,"end":101},"obj":"PR:Q03557"},{"id":"T21","span":{"begin":96,"end":101},"obj":"PR:P34708"},{"id":"T22","span":{"begin":96,"end":101},"obj":"PR:Q5AK64"},{"id":"T23","span":{"begin":102,"end":105},"obj":"PR:P04626"},{"id":"T24","span":{"begin":102,"end":105},"obj":"PR:000002082"},{"id":"T25","span":{"begin":102,"end":105},"obj":"PR:000011145"},{"id":"T26","span":{"begin":102,"end":105},"obj":"PR:P70424"},{"id":"T28","span":{"begin":102,"end":105},"obj":"PR:000011149"},{"id":"T29","span":{"begin":102,"end":105},"obj":"PR:O35657"},{"id":"T30","span":{"begin":102,"end":105},"obj":"PR:P06494"},{"id":"T31","span":{"begin":102,"end":105},"obj":"PR:P29503"},{"id":"T27","span":{"begin":102,"end":105},"obj":"CHEBI:23995"},{"id":"T32","span":{"begin":106,"end":111},"obj":"10090"},{"id":"T33","span":{"begin":106,"end":111},"obj":"D051379"},{"id":"T36","span":{"begin":126,"end":143},"obj":"D002278"},{"id":"T37","span":{"begin":126,"end":143},"obj":"D002278"},{"id":"T39","span":{"begin":145,"end":149},"obj":"CVCL_5552"},{"id":"T38","span":{"begin":145,"end":149},"obj":"D002285"},{"id":"T40","span":{"begin":145,"end":149},"obj":"D002285"},{"id":"T41","span":{"begin":190,"end":196},"obj":"UBERON:0000310"},{"id":"T42","span":{"begin":190,"end":203},"obj":"D001943"},{"id":"T43","span":{"begin":190,"end":203},"obj":"D001943"},{"id":"T45","span":{"begin":259,"end":263},"obj":"CVCL_5552"},{"id":"T44","span":{"begin":259,"end":263},"obj":"D002285"},{"id":"T46","span":{"begin":259,"end":263},"obj":"D002285"},{"id":"T48","span":{"begin":277,"end":293},"obj":"O62725"},{"id":"T49","span":{"begin":277,"end":293},"obj":"Q05769"},{"id":"T50","span":{"begin":277,"end":293},"obj":"P35355"},{"id":"T51","span":{"begin":277,"end":293},"obj":"P79208"},{"id":"T52","span":{"begin":277,"end":293},"obj":"P35354"},{"id":"T53","span":{"begin":277,"end":293},"obj":"O02768"},{"id":"T54","span":{"begin":277,"end":293},"obj":"PR:000013428"},{"id":"T55","span":{"begin":277,"end":293},"obj":"P27607"},{"id":"T56","span":{"begin":277,"end":293},"obj":"O19183"},{"id":"T57","span":{"begin":277,"end":293},"obj":"O62698"},{"id":"T58","span":{"begin":277,"end":293},"obj":"P70682"},{"id":"T59","span":{"begin":277,"end":293},"obj":"D051546"},{"id":"T65","span":{"begin":295,"end":298},"obj":"CVCL_E534"},{"id":"T68","span":{"begin":295,"end":300},"obj":"PR:Q9MIY7"},{"id":"T69","span":{"begin":295,"end":300},"obj":"P35354"},{"id":"T70","span":{"begin":295,"end":300},"obj":"P27607"},{"id":"T71","span":{"begin":295,"end":300},"obj":"PR:O62698"},{"id":"T72","span":{"begin":295,"end":300},"obj":"PR:000025365"},{"id":"T73","span":{"begin":295,"end":300},"obj":"P79208"},{"id":"T74","span":{"begin":295,"end":300},"obj":"PR:P21534"},{"id":"T75","span":{"begin":295,"end":300},"obj":"O19183"},{"id":"T76","span":{"begin":295,"end":300},"obj":"P70682"},{"id":"T77","span":{"begin":295,"end":300},"obj":"PR:P00410"},{"id":"T78","span":{"begin":295,"end":300},"obj":"PR:P00406"},{"id":"T79","span":{"begin":295,"end":300},"obj":"O62725"},{"id":"T80","span":{"begin":295,"end":300},"obj":"P35355"},{"id":"T81","span":{"begin":295,"end":300},"obj":"PR:P35354"},{"id":"T82","span":{"begin":295,"end":300},"obj":"PR:000013428"},{"id":"T83","span":{"begin":295,"end":300},"obj":"O62698"},{"id":"T84","span":{"begin":295,"end":300},"obj":"PR:P00403"},{"id":"T85","span":{"begin":295,"end":300},"obj":"Q05769"},{"id":"T86","span":{"begin":295,"end":300},"obj":"PR:P24894"},{"id":"T87","span":{"begin":295,"end":300},"obj":"PR:P00405"},{"id":"T88","span":{"begin":295,"end":300},"obj":"O02768"},{"id":"T89","span":{"begin":295,"end":300},"obj":"PR:P93285"},{"id":"T90","span":{"begin":295,"end":300},"obj":"PR:Q05769"},{"id":"T91","span":{"begin":295,"end":300},"obj":"PR:P35355"},{"id":"T92","span":{"begin":295,"end":300},"obj":"PR:P79208"},{"id":"T94","span":{"begin":349,"end":353},"obj":"CVCL_5552"},{"id":"T93","span":{"begin":349,"end":353},"obj":"D002285"},{"id":"T95","span":{"begin":349,"end":353},"obj":"D002285"},{"id":"T96","span":{"begin":361,"end":370},"obj":"140587"},{"id":"T97","span":{"begin":361,"end":370},"obj":"D000068579"},{"id":"T98","span":{"begin":361,"end":370},"obj":"D000068579"},{"id":"T99","span":{"begin":361,"end":370},"obj":"CHEBI:41423"},{"id":"T100","span":{"begin":389,"end":411},"obj":"CHEBI:35472"},{"id":"T107","span":{"begin":438,"end":441},"obj":"CVCL_E534"},{"id":"T110","span":{"begin":438,"end":443},"obj":"PR:Q9MIY7"},{"id":"T111","span":{"begin":438,"end":443},"obj":"P35354"},{"id":"T112","span":{"begin":438,"end":443},"obj":"P27607"},{"id":"T113","span":{"begin":438,"end":443},"obj":"PR:O62698"},{"id":"T114","span":{"begin":438,"end":443},"obj":"PR:000025365"},{"id":"T115","span":{"begin":438,"end":443},"obj":"P79208"},{"id":"T116","span":{"begin":438,"end":443},"obj":"PR:P21534"},{"id":"T117","span":{"begin":438,"end":443},"obj":"O19183"},{"id":"T118","span":{"begin":438,"end":443},"obj":"P70682"},{"id":"T119","span":{"begin":438,"end":443},"obj":"PR:P00410"},{"id":"T120","span":{"begin":438,"end":443},"obj":"PR:P00406"},{"id":"T121","span":{"begin":438,"end":443},"obj":"O62725"},{"id":"T122","span":{"begin":438,"end":443},"obj":"P35355"},{"id":"T123","span":{"begin":438,"end":443},"obj":"PR:P35354"},{"id":"T124","span":{"begin":438,"end":443},"obj":"PR:000013428"},{"id":"T125","span":{"begin":438,"end":443},"obj":"O62698"},{"id":"T126","span":{"begin":438,"end":443},"obj":"PR:P00403"},{"id":"T127","span":{"begin":438,"end":443},"obj":"Q05769"},{"id":"T128","span":{"begin":438,"end":443},"obj":"PR:P24894"},{"id":"T129","span":{"begin":438,"end":443},"obj":"PR:P00405"},{"id":"T130","span":{"begin":438,"end":443},"obj":"O02768"},{"id":"T131","span":{"begin":438,"end":443},"obj":"PR:P93285"},{"id":"T132","span":{"begin":438,"end":443},"obj":"PR:Q05769"},{"id":"T133","span":{"begin":438,"end":443},"obj":"PR:P35355"},{"id":"T134","span":{"begin":438,"end":443},"obj":"PR:P79208"},{"id":"T140","span":{"begin":481,"end":484},"obj":"CVCL_E534"},{"id":"T143","span":{"begin":481,"end":486},"obj":"PR:Q9MIY7"},{"id":"T144","span":{"begin":481,"end":486},"obj":"P35354"},{"id":"T145","span":{"begin":481,"end":486},"obj":"P27607"},{"id":"T146","span":{"begin":481,"end":486},"obj":"PR:O62698"},{"id":"T147","span":{"begin":481,"end":486},"obj":"PR:000025365"},{"id":"T148","span":{"begin":481,"end":486},"obj":"P79208"},{"id":"T149","span":{"begin":481,"end":486},"obj":"PR:P21534"},{"id":"T150","span":{"begin":481,"end":486},"obj":"O19183"},{"id":"T151","span":{"begin":481,"end":486},"obj":"P70682"},{"id":"T152","span":{"begin":481,"end":486},"obj":"PR:P00410"},{"id":"T153","span":{"begin":481,"end":486},"obj":"PR:P00406"},{"id":"T154","span":{"begin":481,"end":486},"obj":"O62725"},{"id":"T155","span":{"begin":481,"end":486},"obj":"P35355"},{"id":"T156","span":{"begin":481,"end":486},"obj":"PR:P35354"},{"id":"T157","span":{"begin":481,"end":486},"obj":"PR:000013428"},{"id":"T158","span":{"begin":481,"end":486},"obj":"O62698"},{"id":"T159","span":{"begin":481,"end":486},"obj":"PR:P00403"},{"id":"T160","span":{"begin":481,"end":486},"obj":"Q05769"},{"id":"T161","span":{"begin":481,"end":486},"obj":"PR:P24894"},{"id":"T162","span":{"begin":481,"end":486},"obj":"PR:P00405"},{"id":"T163","span":{"begin":481,"end":486},"obj":"O02768"},{"id":"T164","span":{"begin":481,"end":486},"obj":"PR:P93285"},{"id":"T165","span":{"begin":481,"end":486},"obj":"PR:Q05769"},{"id":"T166","span":{"begin":481,"end":486},"obj":"PR:P35355"},{"id":"T167","span":{"begin":481,"end":486},"obj":"PR:P79208"},{"id":"T168","span":{"begin":501,"end":510},"obj":"140587"},{"id":"T169","span":{"begin":501,"end":510},"obj":"D000068579"},{"id":"T170","span":{"begin":501,"end":510},"obj":"D000068579"},{"id":"T171","span":{"begin":501,"end":510},"obj":"CHEBI:41423"},{"id":"T172","span":{"begin":551,"end":557},"obj":"UBERON:0000310"},{"id":"T173","span":{"begin":551,"end":564},"obj":"D001943"},{"id":"T174","span":{"begin":551,"end":564},"obj":"D001943"},{"id":"T175","span":{"begin":597,"end":603},"obj":"UBERON:0000310"},{"id":"T176","span":{"begin":597,"end":610},"obj":"D001943"},{"id":"T177","span":{"begin":597,"end":610},"obj":"D001943"},{"id":"T178","span":{"begin":614,"end":621},"obj":"MGI:87853"},{"id":"T179","span":{"begin":616,"end":621},"obj":"10090"},{"id":"T180","span":{"begin":616,"end":621},"obj":"D051379"},{"id":"T181","span":{"begin":659,"end":667},"obj":"PR:P48775"},{"id":"T182","span":{"begin":662,"end":667},"obj":"D006801"},{"id":"T184","span":{"begin":682,"end":686},"obj":"CVCL_5552"},{"id":"T183","span":{"begin":682,"end":686},"obj":"D002285"},{"id":"T185","span":{"begin":682,"end":686},"obj":"D002285"},{"id":"T186","span":{"begin":705,"end":710},"obj":"10090"},{"id":"T187","span":{"begin":705,"end":710},"obj":"D051379"},{"id":"T192","span":{"begin":717,"end":748},"obj":"11757"},{"id":"T193","span":{"begin":731,"end":736},"obj":"D009369"},{"id":"T194","span":{"begin":731,"end":736},"obj":"D009369"},{"id":"T197","span":{"begin":750,"end":753},"obj":"PR:P04626"},{"id":"T198","span":{"begin":750,"end":753},"obj":"PR:000002082"},{"id":"T199","span":{"begin":750,"end":753},"obj":"PR:000011145"},{"id":"T200","span":{"begin":750,"end":753},"obj":"PR:P70424"},{"id":"T202","span":{"begin":750,"end":753},"obj":"PR:000011149"},{"id":"T203","span":{"begin":750,"end":753},"obj":"PR:O35657"},{"id":"T204","span":{"begin":750,"end":753},"obj":"PR:P06494"},{"id":"T205","span":{"begin":750,"end":753},"obj":"PR:P29503"},{"id":"T201","span":{"begin":750,"end":753},"obj":"CHEBI:23995"},{"id":"T206","span":{"begin":793,"end":797},"obj":"PR:000005054"},{"id":"T208","span":{"begin":793,"end":797},"obj":"O89094"},{"id":"T207","span":{"begin":793,"end":797},"obj":"D051379"},{"id":"T209","span":{"begin":793,"end":797},"obj":"10095"},{"id":"T211","span":{"begin":806,"end":809},"obj":"PR:P63003-1"},{"id":"T212","span":{"begin":806,"end":809},"obj":"PR:Q2G0B1"},{"id":"T213","span":{"begin":806,"end":809},"obj":"PR:Q8VHJ4"},{"id":"T210","span":{"begin":806,"end":809},"obj":"10116"},{"id":"T214","span":{"begin":806,"end":809},"obj":"D051381"},{"id":"T215","span":{"begin":810,"end":815},"obj":"PR:P04626"},{"id":"T216","span":{"begin":810,"end":815},"obj":"PR:000002082"},{"id":"T217","span":{"begin":810,"end":815},"obj":"PR:Q03557"},{"id":"T218","span":{"begin":810,"end":815},"obj":"PR:P34708"},{"id":"T219","span":{"begin":810,"end":815},"obj":"PR:Q5AK64"},{"id":"T220","span":{"begin":816,"end":819},"obj":"PR:P04626"},{"id":"T221","span":{"begin":816,"end":819},"obj":"PR:000002082"},{"id":"T222","span":{"begin":816,"end":819},"obj":"PR:000011145"},{"id":"T223","span":{"begin":816,"end":819},"obj":"PR:P70424"},{"id":"T225","span":{"begin":816,"end":819},"obj":"PR:000011149"},{"id":"T226","span":{"begin":816,"end":819},"obj":"PR:O35657"},{"id":"T227","span":{"begin":816,"end":819},"obj":"PR:P06494"},{"id":"T228","span":{"begin":816,"end":819},"obj":"PR:P29503"},{"id":"T224","span":{"begin":816,"end":819},"obj":"CHEBI:23995"},{"id":"T229","span":{"begin":820,"end":829},"obj":"SO:0000902"},{"id":"T231","span":{"begin":855,"end":859},"obj":"CVCL_5552"},{"id":"T230","span":{"begin":855,"end":859},"obj":"D002285"},{"id":"T232","span":{"begin":855,"end":859},"obj":"D002285"},{"id":"T233","span":{"begin":898,"end":907},"obj":"140587"},{"id":"T234","span":{"begin":898,"end":907},"obj":"D000068579"},{"id":"T235","span":{"begin":898,"end":907},"obj":"D000068579"},{"id":"T236","span":{"begin":898,"end":907},"obj":"CHEBI:41423"},{"id":"T237","span":{"begin":913,"end":916},"obj":"Q6I7B6"},{"id":"T238","span":{"begin":967,"end":972},"obj":"D009369"},{"id":"T239","span":{"begin":967,"end":972},"obj":"D009369"},{"id":"T240","span":{"begin":995,"end":1000},"obj":"D009369"},{"id":"T241","span":{"begin":995,"end":1000},"obj":"D009369"},{"id":"T242","span":{"begin":1036,"end":1040},"obj":"PR:000005054"},{"id":"T244","span":{"begin":1036,"end":1040},"obj":"O89094"},{"id":"T243","span":{"begin":1036,"end":1040},"obj":"D051379"},{"id":"T245","span":{"begin":1036,"end":1040},"obj":"10095"},{"id":"T246","span":{"begin":1064,"end":1068},"obj":"CHEBI:23888"},{"id":"T247","span":{"begin":1088,"end":1101},"obj":"D063646"},{"id":"T248","span":{"begin":1088,"end":1101},"obj":"D063646"},{"id":"T249","span":{"begin":1164,"end":1170},"obj":"D009369"},{"id":"T250","span":{"begin":1164,"end":1170},"obj":"D009369"},{"id":"T251","span":{"begin":1183,"end":1187},"obj":"UBERON:0002048"},{"id":"T252","span":{"begin":1188,"end":1198},"obj":"D009362"},{"id":"T253","span":{"begin":1188,"end":1198},"obj":"D009362"},{"id":"T254","span":{"begin":1213,"end":1226},"obj":"CHEBI:26333"},{"id":"T255","span":{"begin":1268,"end":1274},"obj":"D009369"},{"id":"T256","span":{"begin":1268,"end":1274},"obj":"D009369"},{"id":"T257","span":{"begin":1286,"end":1290},"obj":"PR:000005054"},{"id":"T259","span":{"begin":1286,"end":1290},"obj":"O89094"},{"id":"T258","span":{"begin":1286,"end":1290},"obj":"D051379"},{"id":"T260","span":{"begin":1286,"end":1290},"obj":"10095"},{"id":"T261","span":{"begin":1305,"end":1314},"obj":"140587"},{"id":"T262","span":{"begin":1305,"end":1314},"obj":"D000068579"},{"id":"T263","span":{"begin":1305,"end":1314},"obj":"D000068579"},{"id":"T264","span":{"begin":1305,"end":1314},"obj":"CHEBI:41423"},{"id":"T265","span":{"begin":1347,"end":1356},"obj":"GO:0097194"},{"id":"T266","span":{"begin":1347,"end":1356},"obj":"GO:0006915"},{"id":"T267","span":{"begin":1371,"end":1405},"obj":"D042461"},{"id":"T269","span":{"begin":1371,"end":1405},"obj":"D042461"},{"id":"T268","span":{"begin":1371,"end":1405},"obj":"GO:0005172"},{"id":"T272","span":{"begin":1392,"end":1405},"obj":"P08441"},{"id":"T273","span":{"begin":1392,"end":1405},"obj":"P08072"},{"id":"T274","span":{"begin":1392,"end":1405},"obj":"Q776B5"},{"id":"T275","span":{"begin":1392,"end":1405},"obj":"Q6RZT5"},{"id":"T276","span":{"begin":1392,"end":1405},"obj":"Q8V307"},{"id":"T282","span":{"begin":1554,"end":1557},"obj":"CVCL_E534"},{"id":"T285","span":{"begin":1554,"end":1559},"obj":"PR:Q9MIY7"},{"id":"T286","span":{"begin":1554,"end":1559},"obj":"P35354"},{"id":"T287","span":{"begin":1554,"end":1559},"obj":"P27607"},{"id":"T288","span":{"begin":1554,"end":1559},"obj":"PR:O62698"},{"id":"T289","span":{"begin":1554,"end":1559},"obj":"PR:000025365"},{"id":"T290","span":{"begin":1554,"end":1559},"obj":"P79208"},{"id":"T291","span":{"begin":1554,"end":1559},"obj":"PR:P21534"},{"id":"T292","span":{"begin":1554,"end":1559},"obj":"O19183"},{"id":"T293","span":{"begin":1554,"end":1559},"obj":"P70682"},{"id":"T294","span":{"begin":1554,"end":1559},"obj":"PR:P00410"},{"id":"T295","span":{"begin":1554,"end":1559},"obj":"PR:P00406"},{"id":"T296","span":{"begin":1554,"end":1559},"obj":"O62725"},{"id":"T297","span":{"begin":1554,"end":1559},"obj":"P35355"},{"id":"T298","span":{"begin":1554,"end":1559},"obj":"PR:P35354"},{"id":"T299","span":{"begin":1554,"end":1559},"obj":"PR:000013428"},{"id":"T300","span":{"begin":1554,"end":1559},"obj":"O62698"},{"id":"T301","span":{"begin":1554,"end":1559},"obj":"PR:P00403"},{"id":"T302","span":{"begin":1554,"end":1559},"obj":"Q05769"},{"id":"T303","span":{"begin":1554,"end":1559},"obj":"PR:P24894"},{"id":"T304","span":{"begin":1554,"end":1559},"obj":"PR:P00405"},{"id":"T305","span":{"begin":1554,"end":1559},"obj":"O02768"},{"id":"T306","span":{"begin":1554,"end":1559},"obj":"PR:P93285"},{"id":"T307","span":{"begin":1554,"end":1559},"obj":"PR:Q05769"},{"id":"T308","span":{"begin":1554,"end":1559},"obj":"PR:P35355"},{"id":"T309","span":{"begin":1554,"end":1559},"obj":"PR:P79208"},{"id":"T310","span":{"begin":1564,"end":1570},"obj":"UBERON:0000310"},{"id":"T311","span":{"begin":1564,"end":1577},"obj":"D001943"},{"id":"T312","span":{"begin":1564,"end":1577},"obj":"D001943"}],"attributes":[{"subj":"T2","pred":"source","obj":"c_corpus"},{"subj":"T3","pred":"source","obj":"c_corpus"},{"subj":"T4","pred":"source","obj":"c_corpus"},{"subj":"T5","pred":"source","obj":"c_corpus"},{"subj":"T6","pred":"source","obj":"c_corpus"},{"subj":"T7","pred":"source","obj":"c_corpus"},{"subj":"T8","pred":"source","obj":"c_corpus"},{"subj":"T9","pred":"source","obj":"c_corpus"},{"subj":"T10","pred":"source","obj":"c_corpus"},{"subj":"T11","pred":"source","obj":"c_corpus"},{"subj":"T12","pred":"source","obj":"c_corpus"},{"subj":"T13","pred":"source","obj":"c_corpus"},{"subj":"T14","pred":"source","obj":"c_corpus"},{"subj":"T15","pred":"source","obj":"c_corpus"},{"subj":"T16","pred":"source","obj":"c_corpus"},{"subj":"T17","pred":"source","obj":"c_corpus"},{"subj":"T18","pred":"source","obj":"c_corpus"},{"subj":"T19","pred":"source","obj":"c_corpus"},{"subj":"T20","pred":"source","obj":"c_corpus"},{"subj":"T21","pred":"source","obj":"c_corpus"},{"subj":"T22","pred":"source","obj":"c_corpus"},{"subj":"T23","pred":"source","obj":"c_corpus"},{"subj":"T24","pred":"source","obj":"c_corpus"},{"subj":"T25","pred":"source","obj":"c_corpus"},{"subj":"T26","pred":"source","obj":"c_corpus"},{"subj":"T28","pred":"source","obj":"c_corpus"},{"subj":"T29","pred":"source","obj":"c_corpus"},{"subj":"T30","pred":"source","obj":"c_corpus"},{"subj":"T31","pred":"source","obj":"c_corpus"},{"subj":"T27","pred":"source","obj":"c_corpus"},{"subj":"T32","pred":"source","obj":"c_corpus"},{"subj":"T33","pred":"source","obj":"c_corpus"},{"subj":"T36","pred":"source","obj":"c_corpus"},{"subj":"T37","pred":"source","obj":"c_corpus"},{"subj":"T39","pred":"source","obj":"c_corpus"},{"subj":"T38","pred":"source","obj":"c_corpus"},{"subj":"T40","pred":"source","obj":"c_corpus"},{"subj":"T41","pred":"source","obj":"c_corpus"},{"subj":"T42","pred":"source","obj":"c_corpus"},{"subj":"T43","pred":"source","obj":"c_corpus"},{"subj":"T45","pred":"source","obj":"c_corpus"},{"subj":"T44","pred":"source","obj":"c_corpus"},{"subj":"T46","pred":"source","obj":"c_corpus"},{"subj":"T48","pred":"source","obj":"c_corpus"},{"subj":"T49","pred":"source","obj":"c_corpus"},{"subj":"T50","pred":"source","obj":"c_corpus"},{"subj":"T51","pred":"source","obj":"c_corpus"},{"subj":"T52","pred":"source","obj":"c_corpus"},{"subj":"T53","pred":"source","obj":"c_corpus"},{"subj":"T54","pred":"source","obj":"c_corpus"},{"subj":"T55","pred":"source","obj":"c_corpus"},{"subj":"T56","pred":"source","obj":"c_corpus"},{"subj":"T57","pred":"source","obj":"c_corpus"},{"subj":"T58","pred":"source","obj":"c_corpus"},{"subj":"T59","pred":"source","obj":"c_corpus"},{"subj":"T65","pred":"source","obj":"c_corpus"},{"subj":"T68","pred":"source","obj":"c_corpus"},{"subj":"T69","pred":"source","obj":"c_corpus"},{"subj":"T70","pred":"source","obj":"c_corpus"},{"subj":"T71","pred":"source","obj":"c_corpus"},{"subj":"T72","pred":"source","obj":"c_corpus"},{"subj":"T73","pred":"source","obj":"c_corpus"},{"subj":"T74","pred":"source","obj":"c_corpus"},{"subj":"T75","pred":"source","obj":"c_corpus"},{"subj":"T76","pred":"source","obj":"c_corpus"},{"subj":"T77","pred":"source","obj":"c_corpus"},{"subj":"T78","pred":"source","obj":"c_corpus"},{"subj":"T79","pred":"source","obj":"c_corpus"},{"subj":"T80","pred":"source","obj":"c_corpus"},{"subj":"T81","pred":"source","obj":"c_corpus"},{"subj":"T82","pred":"source","obj":"c_corpus"},{"subj":"T83","pred":"source","obj":"c_corpus"},{"subj":"T84","pred":"source","obj":"c_corpus"},{"subj":"T85","pred":"source","obj":"c_corpus"},{"subj":"T86","pred":"source","obj":"c_corpus"},{"subj":"T87","pred":"source","obj":"c_corpus"},{"subj":"T88","pred":"source","obj":"c_corpus"},{"subj":"T89","pred":"source","obj":"c_corpus"},{"subj":"T90","pred":"source","obj":"c_corpus"},{"subj":"T91","pred":"source","obj":"c_corpus"},{"subj":"T92","pred":"source","obj":"c_corpus"},{"subj":"T94","pred":"source","obj":"c_corpus"},{"subj":"T93","pred":"source","obj":"c_corpus"},{"subj":"T95","pred":"source","obj":"c_corpus"},{"subj":"T96","pred":"source","obj":"c_corpus"},{"subj":"T97","pred":"source","obj":"c_corpus"},{"subj":"T98","pred":"source","obj":"c_corpus"},{"subj":"T99","pred":"source","obj":"c_corpus"},{"subj":"T100","pred":"source","obj":"c_corpus"},{"subj":"T107","pred":"source","obj":"c_corpus"},{"subj":"T110","pred":"source","obj":"c_corpus"},{"subj":"T111","pred":"source","obj":"c_corpus"},{"subj":"T112","pred":"source","obj":"c_corpus"},{"subj":"T113","pred":"source","obj":"c_corpus"},{"subj":"T114","pred":"source","obj":"c_corpus"},{"subj":"T115","pred":"source","obj":"c_corpus"},{"subj":"T116","pred":"source","obj":"c_corpus"},{"subj":"T117","pred":"source","obj":"c_corpus"},{"subj":"T118","pred":"source","obj":"c_corpus"},{"subj":"T119","pred":"source","obj":"c_corpus"},{"subj":"T120","pred":"source","obj":"c_corpus"},{"subj":"T121","pred":"source","obj":"c_corpus"},{"subj":"T122","pred":"source","obj":"c_corpus"},{"subj":"T123","pred":"source","obj":"c_corpus"},{"subj":"T124","pred":"source","obj":"c_corpus"},{"subj":"T125","pred":"source","obj":"c_corpus"},{"subj":"T126","pred":"source","obj":"c_corpus"},{"subj":"T127","pred":"source","obj":"c_corpus"},{"subj":"T128","pred":"source","obj":"c_corpus"},{"subj":"T129","pred":"source","obj":"c_corpus"},{"subj":"T130","pred":"source","obj":"c_corpus"},{"subj":"T131","pred":"source","obj":"c_corpus"},{"subj":"T132","pred":"source","obj":"c_corpus"},{"subj":"T133","pred":"source","obj":"c_corpus"},{"subj":"T134","pred":"source","obj":"c_corpus"},{"subj":"T140","pred":"source","obj":"c_corpus"},{"subj":"T143","pred":"source","obj":"c_corpus"},{"subj":"T144","pred":"source","obj":"c_corpus"},{"subj":"T145","pred":"source","obj":"c_corpus"},{"subj":"T146","pred":"source","obj":"c_corpus"},{"subj":"T147","pred":"source","obj":"c_corpus"},{"subj":"T148","pred":"source","obj":"c_corpus"},{"subj":"T149","pred":"source","obj":"c_corpus"},{"subj":"T150","pred":"source","obj":"c_corpus"},{"subj":"T151","pred":"source","obj":"c_corpus"},{"subj":"T152","pred":"source","obj":"c_corpus"},{"subj":"T153","pred":"source","obj":"c_corpus"},{"subj":"T154","pred":"source","obj":"c_corpus"},{"subj":"T155","pred":"source","obj":"c_corpus"},{"subj":"T156","pred":"source","obj":"c_corpus"},{"subj":"T157","pred":"source","obj":"c_corpus"},{"subj":"T158","pred":"source","obj":"c_corpus"},{"subj":"T159","pred":"source","obj":"c_corpus"},{"subj":"T160","pred":"source","obj":"c_corpus"},{"subj":"T161","pred":"source","obj":"c_corpus"},{"subj":"T162","pred":"source","obj":"c_corpus"},{"subj":"T163","pred":"source","obj":"c_corpus"},{"subj":"T164","pred":"source","obj":"c_corpus"},{"subj":"T165","pred":"source","obj":"c_corpus"},{"subj":"T166","pred":"source","obj":"c_corpus"},{"subj":"T167","pred":"source","obj":"c_corpus"},{"subj":"T168","pred":"source","obj":"c_corpus"},{"subj":"T169","pred":"source","obj":"c_corpus"},{"subj":"T170","pred":"source","obj":"c_corpus"},{"subj":"T171","pred":"source","obj":"c_corpus"},{"subj":"T172","pred":"source","obj":"c_corpus"},{"subj":"T173","pred":"source","obj":"c_corpus"},{"subj":"T174","pred":"source","obj":"c_corpus"},{"subj":"T175","pred":"source","obj":"c_corpus"},{"subj":"T176","pred":"source","obj":"c_corpus"},{"subj":"T177","pred":"source","obj":"c_corpus"},{"subj":"T178","pred":"source","obj":"c_corpus"},{"subj":"T179","pred":"source","obj":"c_corpus"},{"subj":"T180","pred":"source","obj":"c_corpus"},{"subj":"T181","pred":"source","obj":"c_corpus"},{"subj":"T182","pred":"source","obj":"c_corpus"},{"subj":"T184","pred":"source","obj":"c_corpus"},{"subj":"T183","pred":"source","obj":"c_corpus"},{"subj":"T185","pred":"source","obj":"c_corpus"},{"subj":"T186","pred":"source","obj":"c_corpus"},{"subj":"T187","pred":"source","obj":"c_corpus"},{"subj":"T192","pred":"source","obj":"c_corpus"},{"subj":"T193","pred":"source","obj":"c_corpus"},{"subj":"T194","pred":"source","obj":"c_corpus"},{"subj":"T197","pred":"source","obj":"c_corpus"},{"subj":"T198","pred":"source","obj":"c_corpus"},{"subj":"T199","pred":"source","obj":"c_corpus"},{"subj":"T200","pred":"source","obj":"c_corpus"},{"subj":"T202","pred":"source","obj":"c_corpus"},{"subj":"T203","pred":"source","obj":"c_corpus"},{"subj":"T204","pred":"source","obj":"c_corpus"},{"subj":"T205","pred":"source","obj":"c_corpus"},{"subj":"T201","pred":"source","obj":"c_corpus"},{"subj":"T206","pred":"source","obj":"c_corpus"},{"subj":"T208","pred":"source","obj":"c_corpus"},{"subj":"T207","pred":"source","obj":"c_corpus"},{"subj":"T209","pred":"source","obj":"c_corpus"},{"subj":"T211","pred":"source","obj":"c_corpus"},{"subj":"T212","pred":"source","obj":"c_corpus"},{"subj":"T213","pred":"source","obj":"c_corpus"},{"subj":"T210","pred":"source","obj":"c_corpus"},{"subj":"T214","pred":"source","obj":"c_corpus"},{"subj":"T215","pred":"source","obj":"c_corpus"},{"subj":"T216","pred":"source","obj":"c_corpus"},{"subj":"T217","pred":"source","obj":"c_corpus"},{"subj":"T218","pred":"source","obj":"c_corpus"},{"subj":"T219","pred":"source","obj":"c_corpus"},{"subj":"T220","pred":"source","obj":"c_corpus"},{"subj":"T221","pred":"source","obj":"c_corpus"},{"subj":"T222","pred":"source","obj":"c_corpus"},{"subj":"T223","pred":"source","obj":"c_corpus"},{"subj":"T225","pred":"source","obj":"c_corpus"},{"subj":"T226","pred":"source","obj":"c_corpus"},{"subj":"T227","pred":"source","obj":"c_corpus"},{"subj":"T228","pred":"source","obj":"c_corpus"},{"subj":"T224","pred":"source","obj":"c_corpus"},{"subj":"T229","pred":"source","obj":"c_corpus"},{"subj":"T231","pred":"source","obj":"c_corpus"},{"subj":"T230","pred":"source","obj":"c_corpus"},{"subj":"T232","pred":"source","obj":"c_corpus"},{"subj":"T233","pred":"source","obj":"c_corpus"},{"subj":"T234","pred":"source","obj":"c_corpus"},{"subj":"T235","pred":"source","obj":"c_corpus"},{"subj":"T236","pred":"source","obj":"c_corpus"},{"subj":"T237","pred":"source","obj":"c_corpus"},{"subj":"T238","pred":"source","obj":"c_corpus"},{"subj":"T239","pred":"source","obj":"c_corpus"},{"subj":"T240","pred":"source","obj":"c_corpus"},{"subj":"T241","pred":"source","obj":"c_corpus"},{"subj":"T242","pred":"source","obj":"c_corpus"},{"subj":"T244","pred":"source","obj":"c_corpus"},{"subj":"T243","pred":"source","obj":"c_corpus"},{"subj":"T245","pred":"source","obj":"c_corpus"},{"subj":"T246","pred":"source","obj":"c_corpus"},{"subj":"T247","pred":"source","obj":"c_corpus"},{"subj":"T248","pred":"source","obj":"c_corpus"},{"subj":"T249","pred":"source","obj":"c_corpus"},{"subj":"T250","pred":"source","obj":"c_corpus"},{"subj":"T251","pred":"source","obj":"c_corpus"},{"subj":"T252","pred":"source","obj":"c_corpus"},{"subj":"T253","pred":"source","obj":"c_corpus"},{"subj":"T254","pred":"source","obj":"c_corpus"},{"subj":"T255","pred":"source","obj":"c_corpus"},{"subj":"T256","pred":"source","obj":"c_corpus"},{"subj":"T257","pred":"source","obj":"c_corpus"},{"subj":"T259","pred":"source","obj":"c_corpus"},{"subj":"T258","pred":"source","obj":"c_corpus"},{"subj":"T260","pred":"source","obj":"c_corpus"},{"subj":"T261","pred":"source","obj":"c_corpus"},{"subj":"T262","pred":"source","obj":"c_corpus"},{"subj":"T263","pred":"source","obj":"c_corpus"},{"subj":"T264","pred":"source","obj":"c_corpus"},{"subj":"T265","pred":"source","obj":"c_corpus"},{"subj":"T266","pred":"source","obj":"c_corpus"},{"subj":"T267","pred":"source","obj":"c_corpus"},{"subj":"T269","pred":"source","obj":"c_corpus"},{"subj":"T268","pred":"source","obj":"c_corpus"},{"subj":"T272","pred":"source","obj":"c_corpus"},{"subj":"T273","pred":"source","obj":"c_corpus"},{"subj":"T274","pred":"source","obj":"c_corpus"},{"subj":"T275","pred":"source","obj":"c_corpus"},{"subj":"T276","pred":"source","obj":"c_corpus"},{"subj":"T282","pred":"source","obj":"c_corpus"},{"subj":"T285","pred":"source","obj":"c_corpus"},{"subj":"T286","pred":"source","obj":"c_corpus"},{"subj":"T287","pred":"source","obj":"c_corpus"},{"subj":"T288","pred":"source","obj":"c_corpus"},{"subj":"T289","pred":"source","obj":"c_corpus"},{"subj":"T290","pred":"source","obj":"c_corpus"},{"subj":"T291","pred":"source","obj":"c_corpus"},{"subj":"T292","pred":"source","obj":"c_corpus"},{"subj":"T293","pred":"source","obj":"c_corpus"},{"subj":"T294","pred":"source","obj":"c_corpus"},{"subj":"T295","pred":"source","obj":"c_corpus"},{"subj":"T296","pred":"source","obj":"c_corpus"},{"subj":"T297","pred":"source","obj":"c_corpus"},{"subj":"T298","pred":"source","obj":"c_corpus"},{"subj":"T299","pred":"source","obj":"c_corpus"},{"subj":"T300","pred":"source","obj":"c_corpus"},{"subj":"T301","pred":"source","obj":"c_corpus"},{"subj":"T302","pred":"source","obj":"c_corpus"},{"subj":"T303","pred":"source","obj":"c_corpus"},{"subj":"T304","pred":"source","obj":"c_corpus"},{"subj":"T305","pred":"source","obj":"c_corpus"},{"subj":"T306","pred":"source","obj":"c_corpus"},{"subj":"T307","pred":"source","obj":"c_corpus"},{"subj":"T308","pred":"source","obj":"c_corpus"},{"subj":"T309","pred":"source","obj":"c_corpus"},{"subj":"T310","pred":"source","obj":"c_corpus"},{"subj":"T311","pred":"source","obj":"c_corpus"},{"subj":"T312","pred":"source","obj":"c_corpus"}]},{"project":"Inflammaging","denotations":[{"id":"T1","span":{"begin":0,"end":118},"obj":"Sentence"},{"id":"T2","span":{"begin":119,"end":204},"obj":"Sentence"},{"id":"T3","span":{"begin":205,"end":264},"obj":"Sentence"},{"id":"T4","span":{"begin":265,"end":360},"obj":"Sentence"},{"id":"T5","span":{"begin":361,"end":444},"obj":"Sentence"},{"id":"T6","span":{"begin":445,"end":687},"obj":"Sentence"},{"id":"T7","span":{"begin":688,"end":786},"obj":"Sentence"},{"id":"T8","span":{"begin":787,"end":873},"obj":"Sentence"},{"id":"T9","span":{"begin":874,"end":1041},"obj":"Sentence"},{"id":"T10","span":{"begin":1042,"end":1199},"obj":"Sentence"},{"id":"T11","span":{"begin":1200,"end":1291},"obj":"Sentence"},{"id":"T12","span":{"begin":1292,"end":1436},"obj":"Sentence"},{"id":"T13","span":{"begin":1437,"end":1578},"obj":"Sentence"},{"id":"T1","span":{"begin":0,"end":118},"obj":"Sentence"},{"id":"T2","span":{"begin":119,"end":204},"obj":"Sentence"},{"id":"T3","span":{"begin":205,"end":264},"obj":"Sentence"},{"id":"T4","span":{"begin":265,"end":360},"obj":"Sentence"},{"id":"T5","span":{"begin":361,"end":444},"obj":"Sentence"},{"id":"T6","span":{"begin":445,"end":687},"obj":"Sentence"},{"id":"T7","span":{"begin":688,"end":786},"obj":"Sentence"},{"id":"T8","span":{"begin":787,"end":873},"obj":"Sentence"},{"id":"T9","span":{"begin":874,"end":1041},"obj":"Sentence"},{"id":"T10","span":{"begin":1042,"end":1199},"obj":"Sentence"},{"id":"T11","span":{"begin":1200,"end":1291},"obj":"Sentence"},{"id":"T12","span":{"begin":1292,"end":1436},"obj":"Sentence"},{"id":"T13","span":{"begin":1437,"end":1578},"obj":"Sentence"}],"attributes":[{"subj":"T1","pred":"source","obj":"Inflammaging"},{"subj":"T2","pred":"source","obj":"Inflammaging"},{"subj":"T3","pred":"source","obj":"Inflammaging"},{"subj":"T4","pred":"source","obj":"Inflammaging"},{"subj":"T5","pred":"source","obj":"Inflammaging"},{"subj":"T6","pred":"source","obj":"Inflammaging"},{"subj":"T7","pred":"source","obj":"Inflammaging"},{"subj":"T8","pred":"source","obj":"Inflammaging"},{"subj":"T9","pred":"source","obj":"Inflammaging"},{"subj":"T10","pred":"source","obj":"Inflammaging"},{"subj":"T11","pred":"source","obj":"Inflammaging"},{"subj":"T12","pred":"source","obj":"Inflammaging"},{"subj":"T13","pred":"source","obj":"Inflammaging"},{"subj":"T1","pred":"source","obj":"Inflammaging"},{"subj":"T2","pred":"source","obj":"Inflammaging"},{"subj":"T3","pred":"source","obj":"Inflammaging"},{"subj":"T4","pred":"source","obj":"Inflammaging"},{"subj":"T5","pred":"source","obj":"Inflammaging"},{"subj":"T6","pred":"source","obj":"Inflammaging"},{"subj":"T7","pred":"source","obj":"Inflammaging"},{"subj":"T8","pred":"source","obj":"Inflammaging"},{"subj":"T9","pred":"source","obj":"Inflammaging"},{"subj":"T10","pred":"source","obj":"Inflammaging"},{"subj":"T11","pred":"source","obj":"Inflammaging"},{"subj":"T12","pred":"source","obj":"Inflammaging"},{"subj":"T13","pred":"source","obj":"Inflammaging"}]},{"project":"PubmedHPO","denotations":[{"id":"T1","span":{"begin":190,"end":203},"obj":"HP_0003002"},{"id":"T2","span":{"begin":190,"end":203},"obj":"HP_0100013"},{"id":"T3","span":{"begin":197,"end":203},"obj":"HP_0002664"},{"id":"T4","span":{"begin":551,"end":564},"obj":"HP_0003002"},{"id":"T5","span":{"begin":551,"end":564},"obj":"HP_0100013"},{"id":"T6","span":{"begin":558,"end":564},"obj":"HP_0002664"},{"id":"T7","span":{"begin":597,"end":610},"obj":"HP_0003002"},{"id":"T8","span":{"begin":597,"end":610},"obj":"HP_0100013"},{"id":"T9","span":{"begin":604,"end":610},"obj":"HP_0002664"},{"id":"T10","span":{"begin":731,"end":736},"obj":"HP_0002664"},{"id":"T11","span":{"begin":967,"end":972},"obj":"HP_0002664"},{"id":"T12","span":{"begin":995,"end":1000},"obj":"HP_0002664"},{"id":"T13","span":{"begin":1164,"end":1170},"obj":"HP_0002664"},{"id":"T14","span":{"begin":1268,"end":1274},"obj":"HP_0002664"},{"id":"T15","span":{"begin":1564,"end":1577},"obj":"HP_0003002"},{"id":"T16","span":{"begin":1564,"end":1577},"obj":"HP_0100013"},{"id":"T17","span":{"begin":1571,"end":1577},"obj":"HP_0002664"}],"attributes":[{"subj":"T1","pred":"source","obj":"PubmedHPO"},{"subj":"T2","pred":"source","obj":"PubmedHPO"},{"subj":"T3","pred":"source","obj":"PubmedHPO"},{"subj":"T4","pred":"source","obj":"PubmedHPO"},{"subj":"T5","pred":"source","obj":"PubmedHPO"},{"subj":"T6","pred":"source","obj":"PubmedHPO"},{"subj":"T7","pred":"source","obj":"PubmedHPO"},{"subj":"T8","pred":"source","obj":"PubmedHPO"},{"subj":"T9","pred":"source","obj":"PubmedHPO"},{"subj":"T10","pred":"source","obj":"PubmedHPO"},{"subj":"T11","pred":"source","obj":"PubmedHPO"},{"subj":"T12","pred":"source","obj":"PubmedHPO"},{"subj":"T13","pred":"source","obj":"PubmedHPO"},{"subj":"T14","pred":"source","obj":"PubmedHPO"},{"subj":"T15","pred":"source","obj":"PubmedHPO"},{"subj":"T16","pred":"source","obj":"PubmedHPO"},{"subj":"T17","pred":"source","obj":"PubmedHPO"}]},{"project":"Allie","denotations":[{"id":"SS1_20103725_1_0","span":{"begin":119,"end":143},"obj":"expanded"},{"id":"SS2_20103725_1_0","span":{"begin":145,"end":149},"obj":"abbr"},{"id":"SS1_20103725_3_0","span":{"begin":277,"end":293},"obj":"expanded"},{"id":"SS2_20103725_3_0","span":{"begin":295,"end":300},"obj":"abbr"},{"id":"SS1_20103725_6_0","span":{"begin":717,"end":742},"obj":"expanded"},{"id":"SS2_20103725_6_0","span":{"begin":744,"end":748},"obj":"abbr"}],"relations":[{"id":"AE1_20103725_1_0","pred":"abbreviatedTo","subj":"SS1_20103725_1_0","obj":"SS2_20103725_1_0"},{"id":"AE1_20103725_3_0","pred":"abbreviatedTo","subj":"SS1_20103725_3_0","obj":"SS2_20103725_3_0"},{"id":"AE1_20103725_6_0","pred":"abbreviatedTo","subj":"SS1_20103725_6_0","obj":"SS2_20103725_6_0"}],"attributes":[{"subj":"SS1_20103725_1_0","pred":"source","obj":"Allie"},{"subj":"SS2_20103725_1_0","pred":"source","obj":"Allie"},{"subj":"SS1_20103725_3_0","pred":"source","obj":"Allie"},{"subj":"SS2_20103725_3_0","pred":"source","obj":"Allie"},{"subj":"SS1_20103725_6_0","pred":"source","obj":"Allie"},{"subj":"SS2_20103725_6_0","pred":"source","obj":"Allie"}]},{"project":"UseCases_ArguminSci_Discourse","denotations":[{"id":"T1","span":{"begin":0,"end":118},"obj":"DRI_Background"},{"id":"T2","span":{"begin":119,"end":204},"obj":"DRI_Background"},{"id":"T3","span":{"begin":205,"end":264},"obj":"DRI_Background"},{"id":"T4","span":{"begin":265,"end":360},"obj":"DRI_Background"},{"id":"T5","span":{"begin":361,"end":444},"obj":"DRI_Background"},{"id":"T6","span":{"begin":445,"end":687},"obj":"DRI_Approach"},{"id":"T7","span":{"begin":688,"end":786},"obj":"DRI_Approach"},{"id":"T8","span":{"begin":787,"end":873},"obj":"DRI_Background"},{"id":"T9","span":{"begin":874,"end":1041},"obj":"DRI_Outcome"},{"id":"T10","span":{"begin":1042,"end":1199},"obj":"DRI_Challenge"},{"id":"T11","span":{"begin":1200,"end":1291},"obj":"DRI_Background"},{"id":"T12","span":{"begin":1292,"end":1436},"obj":"DRI_Background"},{"id":"T13","span":{"begin":1437,"end":1578},"obj":"DRI_Outcome"}],"attributes":[{"subj":"T1","pred":"source","obj":"UseCases_ArguminSci_Discourse"},{"subj":"T2","pred":"source","obj":"UseCases_ArguminSci_Discourse"},{"subj":"T3","pred":"source","obj":"UseCases_ArguminSci_Discourse"},{"subj":"T4","pred":"source","obj":"UseCases_ArguminSci_Discourse"},{"subj":"T5","pred":"source","obj":"UseCases_ArguminSci_Discourse"},{"subj":"T6","pred":"source","obj":"UseCases_ArguminSci_Discourse"},{"subj":"T7","pred":"source","obj":"UseCases_ArguminSci_Discourse"},{"subj":"T8","pred":"source","obj":"UseCases_ArguminSci_Discourse"},{"subj":"T9","pred":"source","obj":"UseCases_ArguminSci_Discourse"},{"subj":"T10","pred":"source","obj":"UseCases_ArguminSci_Discourse"},{"subj":"T11","pred":"source","obj":"UseCases_ArguminSci_Discourse"},{"subj":"T12","pred":"source","obj":"UseCases_ArguminSci_Discourse"},{"subj":"T13","pred":"source","obj":"UseCases_ArguminSci_Discourse"}]},{"project":"PubMed_ArguminSci","denotations":[{"id":"T1","span":{"begin":119,"end":204},"obj":"DRI_Background"},{"id":"T2","span":{"begin":205,"end":264},"obj":"DRI_Background"},{"id":"T3","span":{"begin":265,"end":360},"obj":"DRI_Background"},{"id":"T4","span":{"begin":361,"end":444},"obj":"DRI_Background"},{"id":"T5","span":{"begin":445,"end":687},"obj":"DRI_Approach"},{"id":"T6","span":{"begin":688,"end":786},"obj":"DRI_Approach"},{"id":"T7","span":{"begin":787,"end":873},"obj":"DRI_Background"},{"id":"T8","span":{"begin":874,"end":1041},"obj":"DRI_Outcome"},{"id":"T9","span":{"begin":1042,"end":1199},"obj":"DRI_Challenge"},{"id":"T10","span":{"begin":1200,"end":1291},"obj":"DRI_Background"},{"id":"T11","span":{"begin":1292,"end":1436},"obj":"DRI_Background"},{"id":"T12","span":{"begin":1437,"end":1578},"obj":"DRI_Outcome"}],"attributes":[{"subj":"T1","pred":"source","obj":"PubMed_ArguminSci"},{"subj":"T2","pred":"source","obj":"PubMed_ArguminSci"},{"subj":"T3","pred":"source","obj":"PubMed_ArguminSci"},{"subj":"T4","pred":"source","obj":"PubMed_ArguminSci"},{"subj":"T5","pred":"source","obj":"PubMed_ArguminSci"},{"subj":"T6","pred":"source","obj":"PubMed_ArguminSci"},{"subj":"T7","pred":"source","obj":"PubMed_ArguminSci"},{"subj":"T8","pred":"source","obj":"PubMed_ArguminSci"},{"subj":"T9","pred":"source","obj":"PubMed_ArguminSci"},{"subj":"T10","pred":"source","obj":"PubMed_ArguminSci"},{"subj":"T11","pred":"source","obj":"PubMed_ArguminSci"},{"subj":"T12","pred":"source","obj":"PubMed_ArguminSci"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"c_corpus","color":"#ec93cd","default":true},{"id":"Inflammaging","color":"#93e7ec"},{"id":"PubmedHPO","color":"#ecd793"},{"id":"Allie","color":"#bd93ec"},{"id":"UseCases_ArguminSci_Discourse","color":"#93eca3"},{"id":"PubMed_ArguminSci","color":"#ec939c"}]}]}}