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PubMed:2008213 JSONTXT

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sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-84 Sentence denotes Glucose/galactose malabsorption caused by a defect in the Na+/glucose cotransporter.
TextSentencer_T2 85-300 Sentence denotes Glucose/galactose malabsorption (GGM) is an autosomal recessive disease manifesting within the first weeks of life and characterized by a selective failure to absorb dietary glucose and galactose from the intestine.
TextSentencer_T3 301-416 Sentence denotes The consequent severe diarrhoea and dehydration are usually fatal unless these sugars are eliminated from the diet.
TextSentencer_T4 417-546 Sentence denotes Intestinal biopsies of GGM patients have revealed a specific defect in Na(+)-dependent absorption of glucose in the brush border.
TextSentencer_T5 547-676 Sentence denotes Normal glucose absorption is mediated by the Na+/glucose cotransporter in the brush border membrane of the intestinal epithelium.
TextSentencer_T6 677-872 Sentence denotes Cellular influx is driven by the transmembrane Na+ electrochemical potential gradient; thereafter the sugar moves to the blood across the basolateral membrane via the facilitated glucose carrier.
TextSentencer_T7 873-1043 Sentence denotes We have previously cloned and sequenced a Na+/glucose cotransporter from normal human ileum and shown that this gene, SGLT1, resides on the distal q arm of chromosome 22.
TextSentencer_T8 1044-1182 Sentence denotes We have now amplified SGLT1 complementary DNA and genomic DNA from members of a family affected with GGM by the polymerase chain reaction.
TextSentencer_T9 1183-1442 Sentence denotes Sequence analysis of the amplified products has revealed a single missense mutation in SGLT1 which cosegregates with the GGM phenotype and results in a complete loss of Na(+)-dependent glucose transport in Xenopus oocytes injected with this complementary RNA.
T1 0-84 Sentence denotes Glucose/galactose malabsorption caused by a defect in the Na+/glucose cotransporter.
T2 85-300 Sentence denotes Glucose/galactose malabsorption (GGM) is an autosomal recessive disease manifesting within the first weeks of life and characterized by a selective failure to absorb dietary glucose and galactose from the intestine.
T3 301-416 Sentence denotes The consequent severe diarrhoea and dehydration are usually fatal unless these sugars are eliminated from the diet.
T4 417-546 Sentence denotes Intestinal biopsies of GGM patients have revealed a specific defect in Na(+)-dependent absorption of glucose in the brush border.
T5 547-676 Sentence denotes Normal glucose absorption is mediated by the Na+/glucose cotransporter in the brush border membrane of the intestinal epithelium.
T6 677-872 Sentence denotes Cellular influx is driven by the transmembrane Na+ electrochemical potential gradient; thereafter the sugar moves to the blood across the basolateral membrane via the facilitated glucose carrier.
T7 873-1043 Sentence denotes We have previously cloned and sequenced a Na+/glucose cotransporter from normal human ileum and shown that this gene, SGLT1, resides on the distal q arm of chromosome 22.
T8 1044-1182 Sentence denotes We have now amplified SGLT1 complementary DNA and genomic DNA from members of a family affected with GGM by the polymerase chain reaction.
T9 1183-1442 Sentence denotes Sequence analysis of the amplified products has revealed a single missense mutation in SGLT1 which cosegregates with the GGM phenotype and results in a complete loss of Na(+)-dependent glucose transport in Xenopus oocytes injected with this complementary RNA.

DisGeNET

Id Subject Object Predicate Lexical cue
T0 1066-1071 gene:6523 denotes SGLT1
T1 1145-1148 disease:C0268186 denotes GGM
R1 T0 T1 associated_with SGLT1,GGM

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 103-116 HP_0002024 denotes malabsorption
T2 129-148 HP_0000007 denotes autosomal recessive
T3 337-348 HP_0001944 denotes dehydration

DisGeNET5_gene_disease

Id Subject Object Predicate Lexical cue
2008213-8#87#92#gene6523 1270-1275 gene6523 denotes SGLT1
2008213-8#121#124#diseaseC0268186 1304-1307 diseaseC0268186 denotes GGM
87#92#gene6523121#124#diseaseC0268186 2008213-8#87#92#gene6523 2008213-8#121#124#diseaseC0268186 associated_with SGLT1,GGM

performance-test

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 798-803 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
PD-UBERON-AE-B_T2 290-299 http://purl.obolibrary.org/obo/UBERON_0000160 denotes intestine
PD-UBERON-AE-B_T3 417-427 http://purl.obolibrary.org/obo/UBERON_0000160 denotes Intestinal
PD-UBERON-AE-B_T4 654-664 http://purl.obolibrary.org/obo/UBERON_0000160 denotes intestinal
PD-UBERON-AE-B_T5 654-675 http://purl.obolibrary.org/obo/UBERON_0001277 denotes intestinal epithelium
PD-UBERON-AE-B_T6 665-675 http://purl.obolibrary.org/obo/UBERON_0000483 denotes epithelium
PD-UBERON-AE-B_T7 959-964 http://purl.obolibrary.org/obo/UBERON_0002116 denotes ileum
PD-UBERON-AE-B_T8 1022-1025 http://purl.obolibrary.org/obo/UBERON_0001460 denotes arm

UBERON-AE

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 290-299 http://purl.obolibrary.org/obo/UBERON_0000160 denotes intestine
PD-UBERON-AE-B_T2 654-664 http://purl.obolibrary.org/obo/UBERON_0000160 denotes intestinal
PD-UBERON-AE-B_T3 654-675 http://purl.obolibrary.org/obo/UBERON_0001277 denotes intestinal epithelium
PD-UBERON-AE-B_T4 665-675 http://purl.obolibrary.org/obo/UBERON_0000483 denotes epithelium
PD-UBERON-AE-B_T5 798-803 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
PD-UBERON-AE-B_T6 959-964 http://purl.obolibrary.org/obo/UBERON_0002116 denotes ileum
PD-UBERON-AE-B_T7 1022-1025 http://purl.obolibrary.org/obo/UBERON_0001460 denotes arm

PubCasesHPO

Id Subject Object Predicate Lexical cue
AB1 103-116 HP:0002024 denotes malabsorption
AB2 337-348 HP:0001944 denotes dehydration

PubCasesORDO

Id Subject Object Predicate Lexical cue
TI1 0-31 ORDO:35710 denotes Glucose/galactose malabsorption

NCBIDiseaseCorpus

Id Subject Object Predicate Lexical cue
T1 0-31 SpecificDisease:OMIM:606824 denotes Glucose/galactose malabsorption
T2 85-116 SpecificDisease:OMIM:606824 denotes Glucose/galactose malabsorption
T3 118-121 SpecificDisease:OMIM:606824 denotes GGM
T4 129-156 DiseaseClass:D030342 denotes autosomal recessive disease
T5 323-332 SpecificDisease:D003967 denotes diarrhoea
T6 337-348 SpecificDisease:D003681 denotes dehydration
T7 440-443 Modifier:OMIM:606824 denotes GGM
T8 1145-1148 SpecificDisease:OMIM:606824 denotes GGM
T9 1304-1307 Modifier:OMIM:606824 denotes GGM

NCBI-Disease-Train

Id Subject Object Predicate Lexical cue database_id
T2250 0-31 SpecificDisease denotes Glucose/galactose malabsorption OMIM:606824
T2251 85-116 SpecificDisease denotes Glucose/galactose malabsorption OMIM:606824
T2252 118-121 SpecificDisease denotes GGM OMIM:606824
T2253 129-156 DiseaseClass denotes autosomal recessive disease D030342
T2254 323-332 SpecificDisease denotes diarrhoea D003967
T2255 337-348 SpecificDisease denotes dehydration D003681
T2256 440-443 Modifier denotes GGM OMIM:606824
T2257 1145-1148 SpecificDisease denotes GGM OMIM:606824
T2258 1304-1307 Modifier denotes GGM OMIM:606824

NCBI-Disease-Corpus-All

Id Subject Object Predicate Lexical cue database_id
T2250 0-31 SpecificDisease denotes Glucose/galactose malabsorption OMIM:606824
T2251 85-116 SpecificDisease denotes Glucose/galactose malabsorption OMIM:606824
T2252 118-121 SpecificDisease denotes GGM OMIM:606824
T2253 129-156 DiseaseClass denotes autosomal recessive disease D030342
T2254 323-332 SpecificDisease denotes diarrhoea D003967
T2255 337-348 SpecificDisease denotes dehydration D003681
T2256 440-443 Modifier denotes GGM OMIM:606824
T2257 1145-1148 SpecificDisease denotes GGM OMIM:606824
T2258 1304-1307 Modifier denotes GGM OMIM:606824

NCBI-Disease-Corpus-2stage-All

Id Subject Object Predicate Lexical cue
T1 85-116 SpecificDisease denotes Glucose/galactose malabsorption
T2 118-121 SpecificDisease denotes GGM
T3 440-443 SpecificDisease denotes GGM
T4 1145-1148 SpecificDisease denotes GGM
T5 1304-1307 SpecificDisease denotes GGM

NCBI-Disease-Corpus-rezarta-All

Id Subject Object Predicate Lexical cue
T1 85-116 SpecificDisease denotes Glucose/galactose malabsorption
T2 118-121 SpecificDisease denotes GGM
T3 440-443 Modifier denotes GGM
T4 1145-1148 Modifier denotes GGM
T5 1304-1307 Modifier denotes GGM

NCBI-Disease-Corpus-4oGuideline-All

Id Subject Object Predicate Lexical cue
T1 85-116 SpecificDisease denotes Glucose/galactose malabsorption
T2 129-156 DiseaseClass denotes autosomal recessive disease
T3 440-443 SpecificDisease denotes GGM
T4 1145-1148 SpecificDisease denotes GGM
T5 1304-1307 SpecificDisease denotes GGM

NCBI-Disease-Corpus-Simple-All

Id Subject Object Predicate Lexical cue
T1 85-122 SpecificDisease denotes Glucose/galactose malabsorption (GGM)
T2 149-156 SpecificDisease denotes disease
T3 323-332 SpecificDisease denotes diarrhoea
T4 337-348 SpecificDisease denotes dehydration
T5 440-443 SpecificDisease denotes GGM
T6 1145-1148 SpecificDisease denotes GGM
T7 1304-1317 SpecificDisease denotes GGM phenotype