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PubMed:2006697 JSONTXT

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jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 11-34 protein denotes glucocorticoid receptor
T2 150-173 protein denotes glucocorticoid receptor
T3 345-390 protein denotes lymphocyte cytosolic glucocorticoid receptors
T4 646-669 protein denotes glucocorticoid receptor
T5 759-783 protein denotes glucocorticoid receptors
T6 967-990 protein denotes glucocorticoid receptor
T7 1044-1076 protein denotes morning glucocorticoid receptors
T8 1309-1344 protein denotes lymphocyte glucocorticoid receptors

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-75 Sentence denotes Lymphocyte glucocorticoid receptor number in posttraumatic stress disorder.
S2 76-308 Sentence denotes OBJECTIVE: The authors' objective was to investigate the possibility that glucocorticoid receptor changes may be involved in the dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis in posttraumatic stress disorder (PTSD).
S3 309-542 Sentence denotes METHOD: They measured the number of lymphocyte cytosolic glucocorticoid receptors and plasma cortisol concentrations in 15 consecutively admitted male combat Vietnam veterans with PTSD and in a normal comparison group of 11 subjects.
S4 543-744 Sentence denotes RESULTS: Both the patients and the normal comparison subjects showed a morning-to-afternoon decline in glucocorticoid receptor concentrations, paralleling the normal diurnal decline in cortisol levels.
S5 745-902 Sentence denotes The number of glucocorticoid receptors was 63% greater in the morning and 26% greater in the afternoon in the patients with PTSD than in the normal subjects.
S6 903-1029 Sentence denotes No group differences in cortisol levels were observed, nor were glucocorticoid receptor number and cortisol levels correlated.
S7 1030-1137 Sentence denotes The number of morning glucocorticoid receptors was positively correlated with symptoms of PTSD and anxiety.
S8 1138-1234 Sentence denotes CONCLUSIONS: These results provide further evidence for a dysregulation of the HPA axis in PTSD.
S9 1235-1495 Sentence denotes The finding that patients with PTSD had a substantially greater number of lymphocyte glucocorticoid receptors than normal comparison subjects is consistent with the authors' previous observations of low 24-hour urinary cortisol excretion in subjects with PTSD.
S10 1496-1599 Sentence denotes Furthermore, the receptor changes observed are opposite of those reported in major depressive disorder.
S11 1600-1779 Sentence denotes The present data, along with other findings of HPA abnormalities in PTSD, support the possibility of a greater negative feedback sensitivity at one or more levels of the HPA axis.

genia-medco-coref

Id Subject Object Predicate Lexical cue
C2 0-34 NP denotes Lymphocyte glucocorticoid receptor
C1 0-41 NP denotes Lymphocyte glucocorticoid receptor number
C3 45-74 NP denotes posttraumatic stress disorder
C4 87-99 NP denotes The authors'
C6 150-173 NP denotes glucocorticoid receptor
C5 150-181 NP denotes glucocorticoid receptor changes
C9 222-262 NP denotes the hypothalamic-pituitary-adrenal (HPA)
C8 222-267 NP denotes the hypothalamic-pituitary-adrenal (HPA) axis
C10 271-307 NP denotes posttraumatic stress disorder (PTSD)
C7 201-307 NP denotes the dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis in posttraumatic stress disorder (PTSD)
C11 317-321 NP denotes They
C12 331-390 NP denotes the number of lymphocyte cytosolic glucocorticoid receptors
C14 489-493 NP denotes PTSD
C13 429-493 NP denotes 15 consecutively admitted male combat Vietnam veterans with PTSD
C15 501-541 NP denotes a normal comparison group of 11 subjects
C16 557-569 NP denotes the patients
C17 574-604 NP denotes the normal comparison subjects
C18 646-669 NP denotes glucocorticoid receptor
C19 728-743 NP denotes cortisol levels
C21 759-783 NP denotes glucocorticoid receptors
C20 745-783 NP denotes The number of glucocorticoid receptors
C23 869-873 NP denotes PTSD
C22 851-873 NP denotes the patients with PTSD
C24 882-901 NP denotes the normal subjects
C25 927-942 NP denotes cortisol levels
C27 967-990 NP denotes glucocorticoid receptor
C26 967-997 NP denotes glucocorticoid receptor number
C28 1002-1017 NP denotes cortisol levels
C29 1120-1124 NP denotes PTSD
C31 1213-1225 NP denotes the HPA axis
C32 1229-1233 NP denotes PTSD
C30 1194-1233 NP denotes a dysregulation of the HPA axis in PTSD
C33 1235-1246 NP denotes The finding
C34 1247-1251 NP denotes that
C36 1266-1270 NP denotes PTSD
C35 1252-1270 NP denotes patients with PTSD
C37 1309-1344 NP denotes lymphocyte glucocorticoid receptors
C38 1350-1376 NP denotes normal comparison subjects
C39 1396-1408 NP denotes the authors'
C41 1490-1494 NP denotes PTSD
C40 1476-1494 NP denotes subjects with PTSD
C44 1509-1521 NP denotes the receptor
C43 1509-1529 NP denotes the receptor changes
C42 1509-1538 NP denotes the receptor changes observed
C45 1555-1560 NP denotes those
C46 1647-1650 NP denotes HPA
C47 1668-1672 NP denotes PTSD
C49 1770-1773 NP denotes HPA
C48 1766-1778 NP denotes the HPA axis
R1 C6 C2 coref-other glucocorticoid receptor,Lymphocyte glucocorticoid receptor
R2 C10 C3 coref-ident posttraumatic stress disorder (PTSD),posttraumatic stress disorder
R3 C11 C4 coref-pron They,The authors'
R4 C12 C1 coref-other the number of lymphocyte cytosolic glucocorticoid receptors,Lymphocyte glucocorticoid receptor number
R5 C14 C10 coref-ident PTSD,posttraumatic stress disorder (PTSD)
R6 C16 C13 coref-ident the patients,15 consecutively admitted male combat Vietnam veterans with PTSD
R7 C17 C15 coref-ident the normal comparison subjects,a normal comparison group of 11 subjects
R8 C18 C6 coref-other glucocorticoid receptor,glucocorticoid receptor
R9 C21 C18 coref-other glucocorticoid receptors,glucocorticoid receptor
R10 C20 C12 coref-other The number of glucocorticoid receptors,the number of lymphocyte cytosolic glucocorticoid receptors
R11 C23 C14 coref-ident PTSD,PTSD
R12 C22 C16 coref-ident the patients with PTSD,the patients
R13 C24 C17 coref-ident the normal subjects,the normal comparison subjects
R14 C25 C19 coref-ident cortisol levels,cortisol levels
R15 C27 C21 coref-other glucocorticoid receptor,glucocorticoid receptors
R16 C26 C20 coref-other glucocorticoid receptor number,The number of glucocorticoid receptors
R17 C28 C25 coref-ident cortisol levels,cortisol levels
R18 C29 C23 coref-ident PTSD,PTSD
R19 C31 C8 coref-ident the HPA axis,the hypothalamic-pituitary-adrenal (HPA) axis
R20 C32 C29 coref-ident PTSD,PTSD
R21 C30 C7 coref-ident a dysregulation of the HPA axis in PTSD,the dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis in posttraumatic stress disorder (PTSD)
R22 C34 C33 coref-relat that,The finding
R23 C36 C32 coref-ident PTSD,PTSD
R24 C35 C22 coref-other patients with PTSD,the patients with PTSD
R25 C37 C27 coref-other lymphocyte glucocorticoid receptors,glucocorticoid receptor
R26 C38 C24 coref-other normal comparison subjects,the normal subjects
R27 C39 C4 coref-ident the authors',The authors'
R28 C41 C36 coref-ident PTSD,PTSD
R29 C40 C35 coref-ident subjects with PTSD,patients with PTSD
R30 C44 C37 coref-other the receptor,lymphocyte glucocorticoid receptors
R31 C42 C5 coref-other the receptor changes observed,glucocorticoid receptor changes
R32 C45 C44 coref-pron those,the receptor
R33 C46 C9 coref-ident HPA,the hypothalamic-pituitary-adrenal (HPA)
R34 C47 C41 coref-ident PTSD,PTSD
R35 C49 C46 coref-ident HPA,HPA
R36 C48 C31 coref-ident the HPA axis,the HPA axis

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 0-10 other_name denotes Lymphocyte
T2 11-34 protein_family_or_group denotes glucocorticoid receptor
T3 150-173 protein_family_or_group denotes glucocorticoid receptor
T4 205-218 other_name denotes dysregulation
T5 226-267 body_part denotes hypothalamic-pituitary-adrenal (HPA) axis
T6 271-300 other_name denotes posttraumatic stress disorder
T7 302-306 other_name denotes PTSD
T8 345-365 protein_domain_or_region denotes lymphocyte cytosolic
T9 366-390 protein_family_or_group denotes glucocorticoid receptors
T10 395-410 lipid denotes plasma cortisol
T11 455-483 multi_cell denotes male combat Vietnam veterans
T12 489-493 other_name denotes PTSD
T13 533-541 multi_cell denotes subjects
T14 561-569 multi_cell denotes patients
T15 578-604 multi_cell denotes normal comparison subjects
T16 646-669 protein_family_or_group denotes glucocorticoid receptor
T17 728-736 lipid denotes cortisol
T18 759-783 protein_family_or_group denotes glucocorticoid receptors
T19 855-863 multi_cell denotes patients
T20 869-873 other_name denotes PTSD
T21 886-901 multi_cell denotes normal subjects
T22 927-935 lipid denotes cortisol
T23 967-990 protein_family_or_group denotes glucocorticoid receptor
T24 1002-1010 lipid denotes cortisol
T25 1044-1051 protein_family_or_group denotes morning
T26 1052-1076 protein_family_or_group denotes glucocorticoid receptors
T27 1120-1124 other_name denotes PTSD
T28 1129-1136 other_name denotes anxiety
T29 1217-1225 body_part denotes HPA axis
T30 1229-1233 other_name denotes PTSD
T31 1252-1260 multi_cell denotes patients
T32 1266-1270 other_name denotes PTSD
T33 1309-1319 protein_family_or_group denotes lymphocyte
T34 1320-1344 protein_family_or_group denotes glucocorticoid receptors
T35 1446-1453 other_name denotes urinary
T36 1454-1462 lipid denotes cortisol
T37 1490-1494 other_name denotes PTSD
T38 1573-1598 other_name denotes major depressive disorder
T39 1647-1664 other_name denotes HPA abnormalities
T40 1668-1672 other_name denotes PTSD
T41 1711-1740 other_name denotes negative feedback sensitivity
T42 1770-1778 body_part denotes HPA axis